Abstract:
:Endotracheal intubation (ETI) and laryngeal mask airway (LMA) in terms of hemodynamics and reaction were compared. A total of 54 general anesthesia patients were randomized into two groups with 27 cases in each group. Acceleration index (ACI), cardiac index (CI), cardiac output (CO), left cardiac work (LCW), systemic circulation resistance (SVR), mean arterial pressure (MAP), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded at 12 time-points: before surgery (T0), start effect (T1), lost consciousness (T2), before ETI or LMA (T3), 1 min (T4), 3 min (T5), 5 min (T6) after ETI or LMA, the beginning of surgery (T7), 30 min (T8), 1 hour (T9) after surgery, the end of surgery (T10) and extubation (T11). In each group these indexes went down and rose up gently during surgery except for T4 (intubation) and T11 (extubation) in ETI. These indexes reached the highest at T11 (extubation). This is due to the stimulus on mucosa and muscle of root of tongue, throat and epiglottis from the windpipe. The stimulus excites sympathetic nerve and increases the release of catecholamine. As a result, the heart beats faster and blood pressure rises. However, the range in the LMA group is smaller especially at T4 and T11. This is most likely due to LMA not stimulating the trachea. SVR, MAP, HR, SBP and DBP were lower in LMA with statistical significance in some time-points. The other indexes such as ACI, CI, CO and LCW were significantly higher in LMA (P<0.05). These results indicated that LMA can be suitable for use in general anesthesia for less stimulation. The airway with LMA in patients undergoing gynecological cancer operation is better than ETI in keeping stable hemodynamics and producing less anesthetic complications with smooth recovery from general anesthesia.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Song Z,Tan J,Fang J,Bian Q,Gu Ldoi
10.3892/ol.2018.9813subject
Has Abstractpub_date
2019-02-01 00:00:00pages
2344-2350issue
2eissn
1792-1074issn
1792-1082pii
OL-0-0-9813journal_volume
17pub_type
杂志文章相关文献
Oncology Letters文献大全abstract::Cisplatin resistance has been a major factor limiting its clinical use as a chemotherapy drug. The present study aimed to investigate whether SET and MYND domain-containing protein 3 (SMYD3), a histone methyltransferase closely associated with tumors can affect the sensitivity of tumors to cisplatin chemotherapy. Real...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.11465
更新日期:2020-05-01 00:00:00
abstract::Expression of mineral dust-induced gene (mdig) in lung cancer NCI-H1650 cells was detected to investigate the effects of mdig on proliferation and apoptosis of NCI-H1650 cells. NCI-H1650 lung cancer cells were cultured in vitro. The expression of mdig in NCI-H1650 cells was lowered using ribonucleic acid interference ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.9528
更新日期:2018-12-01 00:00:00
abstract::The tumor suppressor protein p53 (TP53) gene is associated with various types of cancer; however, little is known about TP53 expression in patients with childhood acute lymphoblastic leukemia (ALL). The aim of the present study was to investigate the prognostic value of TP53 expression in childhood ALL. To achieve thi...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.11064
更新日期:2020-01-01 00:00:00
abstract::Lung cancer is the most frequent cause of cancer-associated mortality among men and women globally. The skeleton is one of the most common metastatic sites. The majority of patients exhibiting bone metastases are treated using systemic therapy or symptom-based palliative approaches without surgery. The present study a...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2016.4190
更新日期:2016-03-01 00:00:00
abstract::The expression level and roles of microRNA-497 (miR-497) have been frequently reported in previous studies on cancer. However, its expression, function and associated molecular mechanisms in retinoblastoma remain unknown. In the present study, miR-497 expression levels in human retinoblastoma tissues, normal retinal t...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.6083
更新日期:2017-06-01 00:00:00
abstract::The aim of the present study was to investigate the long non-coding RNA (lncRNA)-microRNA (miRNA)-mRNA regulatory network in gastric cancer (GC) using bioinformatics analysis. Two mRNA gene expression profiles, GSE79973 and GSE54129, and two miRNA expression profiles, GSE93415 and GSE78091, were downloaded from the Ge...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.10922
更新日期:2019-12-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) contributes to 14.8% of all cancer mortality in Egypt, which has a high prevalence of hepatitis C virus (HCV). We have previously shown alterations in the insulin-like growth factor-1 (IGF-1) receptor signalling pathway during experimental hepatocarcinogenesis. The aim of this study was ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2011.546
更新日期:2012-03-01 00:00:00
abstract::Changes in filamin A (FLNa) expression contribute to the development and progression of numerous malignancies. However, in vitro studies of breast cancer have shown conflicting results. Thus, the present study aimed to detect the expression of FLNa in breast cancer tissue samples and the association with clinicopathol...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1454
更新日期:2013-09-01 00:00:00
abstract::Gastric cancer is one of leading causes of cancer-related mortality worldwide and is a notable disease due to its heterogeneity. Recently, numerous studies have investigated the molecular basis of gastric cancer, involving the alteration of pathogenesis, and invasion and metastasis. With the development of modern tech...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.2959
更新日期:2015-04-01 00:00:00
abstract::Lung cancer is the most common type of malignancy to metastasize to the brain, with the median survival time of patients being 6-11 months. In the present study, the aim was to compare the actionable gene mutation profiles of primary lung adenocarcinoma (LC) samples and LC brain metastasis (LCBM) samples through targe...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.7859
更新日期:2018-04-01 00:00:00
abstract::The role of laparoscopic resection for large gastric gastrointestinal stromal tumors (GISTs), particularly those >5 cm, remains under debate due the possibility of intraoperative tumor rupture. To determine the feasibility and safety of the laparoscopic approach in the treatment of large gastric GISTs, a prospective s...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3547
更新日期:2015-10-01 00:00:00
abstract::Gastric cancer (GC) is the second leading cause of cancer-related mortality worldwide. The usual treatment of GC consists of surgery with additional adjuvant chemotherapy. In the present study, the feasibility and safety of adjuvant S-1 plus oxaliplatin (SOX) chemotherapy for patients with GC and the optimal dosage of...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.2821
更新日期:2015-03-01 00:00:00
abstract::Phospholipase C (PLC) is a membrane-associated enzyme that regulates several cellular behaviors including cell motility, growth, transformation and differentiation. PLC is involved in cancer migration, invasion and drug resistance. However, the expression status and prognostic role of PLCB4 in acute myeloid leukemia (...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.10921
更新日期:2019-12-01 00:00:00
abstract::The aim of the present study was to evaluate the clinical importance of melanoma-associated antigen D4 (MAGE-D4) expression in glioma, and to identify it as a valuable prognostic biomarker and therapeutic target. To achieve this, the expression of MAGE-D4 protein in 124 tumor tissues from patients with glioma was meas...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.7884
更新日期:2018-04-01 00:00:00
abstract::The aim of the present study was to explore the therapeutic effect of 20 kHz ultrasound (US) and microbubbles (MBs) on rabbit VX2 liver tumors by spiral computed tomography (CT) scanning. A total of 16 New Zealand rabbits with hepatic VX2 tumors were divided into four groups: Control, MB, low-frequency US and US + MB....
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.6557
更新日期:2017-09-01 00:00:00
abstract::Interleukin-8 (IL-8), an important inflammatory factor, is induced by Helicobacter pylori infection and is clearly associated with gastric cancer. IL-8 levels have been revealed to correlate significantly with the adhesion, migration and invasion of gastric cancer cells. However, whether IL-8 influences cell prolifera...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.2531
更新日期:2014-12-01 00:00:00
abstract::The purpose of this study was to evaluate the cytotoxic effect of thalidomide on 4T1 and 4THMpc mouse breast cancer cell lines. Mouse breast cancer cells (4T1) and cells derived from metastatic lesions (4THMpc) were treated with various doses of thalidomide [10(-2)-100 µM dissolved in dimethyl sulfoxide (DMSO) as reco...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2012.559
更新日期:2012-04-01 00:00:00
abstract::In the present study, the functions and mechanisms of rotundic acid (RA) underlying its induction of apoptosis in caspase-3-transfected MCF-7 human breast cancer cells (Cas3-MCF-7 cells) were investigated. RA induced apoptosis in Cas3-MCF-7 cells more efficiently compared with that in MCF-7 cells transfected with cont...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.9616
更新日期:2019-01-01 00:00:00
abstract::Previously, the preoperative neutrophil-to-lymphocyte ratio (NLR) has been demonstrated to be a beneficial prognostic marker in patients with upper tract urothelial carcinoma (UTUC). However, to the best of our knowledge, the postoperative NLR has rarely been investigated. Therefore, the present study evaluated the pr...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.10178
更新日期:2019-06-01 00:00:00
abstract::The underlying molecular mechanisms of pancreatic neuroendocrine tumor (pNET) development have not yet been clearly identified. The present study revealed that thrombospondin 2 (THBS2) was downregulated in pNET tissues and cells. Forced expression of THBS2 inhibited the proliferation and migration of pNET cells in vit...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.11273
更新日期:2020-03-01 00:00:00
abstract::Interleukins (ILs) are involved in the occurrence and development of numerous types of cancer, and serve a critical role in the development of effective cancer therapeutics. The aim of the present study was to investigate the effect of IL-27 on chemotherapy resistance in lung cancer cells, and analyze its potential mo...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.12275
更新日期:2021-01-01 00:00:00
abstract::Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.2919
更新日期:2015-04-01 00:00:00
abstract::The present study aimed to investigate the clinical characteristics, diagnosis and treatment of accessory breast cancer, and contribute valuable information regarding this rare tumour to the current literature, ultimately facilitating the development of improved treatment strategies. The present study reported the cas...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3388
更新日期:2015-09-01 00:00:00
abstract::Natural products are a promising source for the development of novel cancer therapies, due to their potential effectiveness and low toxicity profiles. As a main component of Herba oxytropis, 2',4'-dihydroxychalcone (TFC) is known to demonstrate anti-tumor activity in vitro. In the present study, TFC was found to potent...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3795
更新日期:2015-12-01 00:00:00
abstract::A tissue-specific promoter can control downstream gene expression in tissues or organs. The human involucrin (hINV) promoter (pINV) that contains 2474 bp of hINV upstream sequence is able to regulate tissue-specific gene expression. This tissue specificity may be important for the prevention and treatment of human pap...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.2736
更新日期:2015-02-01 00:00:00
abstract::The clinicopathological characteristics of squamous cell/adenosquamous carcinoma (SC/ASC) are currently not well documented, and as the prevalence of SC/ASC is uncommon in gallbladder cancers, a prognostic marker has not yet been found. In the present study, the expression of tumor susceptibility gene (TSG) 101 and pa...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.1886
更新日期:2014-04-01 00:00:00
abstract::In order to estimate the effects of small interfering RNA (siRNA) targeting retinoblastoma binding protein 2 (RBP2) on the proliferation, expression, invasion, migration and tumorigenicity abilities of papillary thyroid carcinoma K1 cells, siRNA targeting RBP2 (RBP2-siRNA) and negative control siRNA were transfected i...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3782
更新日期:2015-12-01 00:00:00
abstract::Lung cancer, a malignant tumor, is the most frequently fatal cancer, with poor survival rates in the advanced stages. In order to improve the understanding of this disease, and to improve the outcomes of patients, additional studies are required. In the present study, differentially expressed genes (DEGs) in patients ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.7329
更新日期:2018-01-01 00:00:00
abstract::Elevated expression of the retinoic acid-metabolizing enzyme cytochrome P450 26A1 (CYP26A1) has been demonstrated to have an oncogenic function in carcinogenesis. In order to address the oncogenic capacity of CYP26A1 in vivo, transgenic mice that ubiquitously overexpressed CYP26A1 driven by the cytomegalovirus promote...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.8599
更新日期:2018-06-01 00:00:00
abstract::Follicular lymphoma (FL) occurs primarily in the gastrointestinal tract, with the stomach being one of the rarest sites. According to the literature, <20 cases of primary gastric FL have been reported, with the number of cases with detailed pathological descriptions being even less. The aim of the present study was to...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.8744
更新日期:2018-07-01 00:00:00