Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review).

abstract：:Lung cancer is one of the most common malignancies worldwide; however, its detailed molecular mechanism remains largely unknown. Long non-coding RNAs (lncRNAs) have been identified to serve critical roles in tumorigenesis. The aim of the present study was to investigate the role of a newly identified lncRNA, overexpre...

journal_title：Oncology letters

authors： Zou Y,Zhang B,Mao Y,Zhang H,Hong W

更新日期：2019-09-01 00:00:00

abstract：:[This retracts the article DOI: 10.3892/ol.2016.5302.]. ...

journal_title：Oncology letters

authors： Zhang XY,Zhang PY

更新日期：2020-11-01 00:00:00

abstract：:Anesthetic effect of propofol combined with remifentanil or sevoflurane intravenous anesthesia on patients undergoing radical gastrectomy was evaluated. The clinical data of 516 cancer patients who received radical gastrectomy in the First Bethune Hospital of Jilin University between January 2011 and December 2017 wer...

journal_title：Oncology letters

authors： Feng Y,Li J,Wang H,Duan Z

更新日期：2019-06-01 00:00:00

abstract：:The CyberKnife® is expected to be a novel local treatment for hepatocellular carcinoma (HCC), however, a long-term follow-up using dynamic computed tomography and magnetic resonance imaging is required to determine the effect of treatment in a number of the affected patients. Therefore, there is a requirement to evalu...

journal_title：Oncology letters

authors： Shiozawa K,Watanabe M,Ikehara T,Kobayashi K,Ochi Y,Suzuki Y,Fuchinoue K,Yoneda M,Kenmochi T,Okubo Y,Mori T,Makino H,Tsukamoto N,Igarashi Y,Sumino Y

更新日期：2016-01-01 00:00:00

abstract：:In the present study, aspiration biopsy cytology (ABC) was used for the diagnosis of peripheral nodular lesions in the lung (PNLL), and liquid-based cytology (LBC) was carried out on the material collected to evaluate it in comparison with the conventional method (CM). The subjects comprised 130 cases that underwent c...

journal_title：Oncology letters

authors： Imura J,Abe K,Uchida Y,Shibata M,Tsunematsu K,Sathoh M,Miwa S,Nakajima T,Nomoto K,Hayashi S,Tsuneyama K

更新日期：2014-03-01 00:00:00

abstract：:The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells i...

journal_title：Oncology letters

authors： Alam B,Majumder R,Akter S,Lee SH

更新日期：2015-02-01 00:00:00

abstract：:Bone metastasis is an uncommon event in advanced gastric cancer patients and bone metastases are rarely detected as isolated lesions. However, eleven years after treatment for locally advanced gastric cancer, including total gastrectomy followed by adjuvant chemotherapy, a 49-year-old female was admitted to the IX Div...

journal_title：Oncology letters

authors： Iovino F,Orditura M,Auriemma PP,Ciorra FR,Giordano G,Orabona C,Bara F,Sergio R,Savastano B,Fabozzi A,Laterza MM,Ventriglia J,Petrillo A,Della Corte CM,DE Vita F

更新日期：2015-03-01 00:00:00

abstract：:Early mitotic inhibitor-1 (Emi1), as a key cell cycle regulatory gene, induces S phase and mitotic entry by controlling anaphase-promoting complex substrates. Emi1 overexpression may be a prognostic factor for patients with invasive breast cancer. However, its expression and clinical significance in esophageal squamou...

journal_title：Oncology letters

authors： Guan C,Zhang J,Zhang J,Shi H,Ni R

更新日期：2016-07-01 00:00:00

abstract：:In our previous study, we demonstrated that type II cGMP-dependent protein kinase (PKG II) was expressed at lower levels in different human cancer cell lines and that exogenous PKG II inhibited epidermal growth factor (EGF)-induced MAPK/ERK signaling. In order to investigate its functions further in this signaling pat...

journal_title：Oncology letters

authors： Tao Y,Gu YJ,Cao ZH,Bian XJ,Lan T,Sang JR,Jiang L,Wang Y,Qian H,Chen YC

更新日期：2012-11-01 00:00:00

abstract：:Prostate cancer is a significant health concern. In the early stages, prostate cancer cells depend on androgens for growth and survival, hence androgen-ablation therapy at this time may be effective in causing tumor regression. However, treatment options for advanced hormone-refractory prostate cancers are still relat...

journal_title：Oncology letters

authors： Zhu G,Wang X,Yang Z,Cao H,Meng Z,Wang Y,Chen D

更新日期：2011-11-01 00:00:00

abstract：:Microglia, once assimilated to peripheral macrophages, in gliomas has long been discussed and currently it is hypothesized to play a pro-tumor role in tumor progression. Uncertain between M1 and M2 polarization, it exchanges signals with glioma cells to create an immunosuppressive microenvironment and stimulates cell ...

journal_title：Oncology letters

authors： Annovazzi L,Mellai M,Bovio E,Mazzetti S,Pollo B,Schiffer D

更新日期：2018-01-01 00:00:00

abstract：:Mangiferin, a flavonoid extracted from the mango tree, possesses anti-inflammatory, antibacterial, anti-herpes simplex and antitumor activity, and is able to affect immune function. The present study investigated the anticancer effects of mangiferin treatment on PC3 human prostate cancer cells, and the potential under...

journal_title：Oncology letters

authors： Li M,Ma H,Yang L,Li P

更新日期：2016-01-01 00:00:00

abstract：:Solitary fibrous tumors (SFTs) represent a rare type of soft tissue tumor. Extrathoracic SFTs (ESFTs) in the soft tissues of the abdominopelvic cavity are extremely rare. Between January 2002 and January 2013, 10 patients were identified with abdominopelvic SFTs at the Northern Jiangsu People's Hospital. The clinicopa...

journal_title：Oncology letters

authors： Wang H,Chen P,Zhao W,Shi L,Gu X,Xu Q

更新日期：2014-04-01 00:00:00

abstract：:For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. To the best of our knowledge, this is the 4th reported case of ost...

journal_title：Oncology letters

authors： Kukwa W,Oziębło A,Oecińska A,Czarnecka AM,Włodarski K,Kukwa A

更新日期：2010-03-01 00:00:00

abstract：:A promising nutraceutical, apigenin, was recently revealed to exhibit biological activity in inhibiting several types of cancer. The effects of apigenin on the growth inhibition and apoptosis of the cholangiocarcinoma HuCCA-1 cell line were investigated. Protein alterations subsequent to apigenin treatment were studie...

journal_title：Oncology letters

authors： Subhasitanont P,Chokchaichamnankit D,Chiablaem K,Keeratichamroen S,Ngiwsara L,Paricharttanakul NM,Lirdprapamongkol K,Weeraphan C,Svasti J,Srisomsap C

更新日期：2017-10-01 00:00:00

abstract：:The present study investigated the correlations of the Tspan-1 gene expression with the clinical characteristics and survival prognoses of patients with advanced gastric cancer. A total of 150 patients with advanced gastric cancer were enrolled in the present study, of whom 84 were at stage II and 66 were at stage III...

journal_title：Oncology letters

authors： Cai Y,Zheng M,Zhao Z,Huang H,Fu W,Xu X

更新日期：2017-09-01 00:00:00

abstract：:Bovine lactoferricin P13 (LfcinB-P13) is a peptide derived from LfcinB. In the present study, the effect of LfcinB-P13 on the human liver cancer cell line SMMC7721 was investigated in vitro and in vivo. The results of the present study indicate that LfcinB-P13 significantly decreased SMMC7721 cell viability in vitro (...

journal_title：Oncology letters

authors： Meng L,Xu G,Li J,Liu W,Jia W,Ma J,Wei D

更新日期：2017-01-01 00:00:00

abstract：:The study aim was to evaluate the association of the expression of serum microribonucleic acid-590 (miR-590) with the risk of lung squamous cell carcinoma (LUSC), clinicopathological staging and prognosis. A total of 237 patients with LUSC and 100 healthy volunteers (control group) were included in the study. Total RN...

journal_title：Oncology letters

authors： Ma Z,Wang Y,He B,Cui J,Zhang C,Wang H,Feng W,Wang B,Wei D,Wu Y,Zeng Y,Yu G

更新日期：2018-02-01 00:00:00

abstract：:Macrophages are a heterogeneous group of phagocytes that play critical roles in inflammation, infection and tumor growth. Macrophages respond to different environmental factors and are thereby polarized into specialized functional subsets. Although hypoxia is an important environmental factor, its impact on human macr...

journal_title：Oncology letters

authors： Ke X,Chen C,Song Y,Cai Q,Li J,Tang Y,Han X,Qu W,Chen A,Wang H,Xu G,Liu D

更新日期：2019-12-01 00:00:00

abstract：:The clinical resistance of non-small cell lung cancer (NSCLC) to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has been linked to EGFR T790M resistance mutations or MET amplifications. Additional mechanisms underlying EGFR-TKI drug resistance remain unclear. The present study demonstrated t...

journal_title：Oncology letters

authors： Zhai Y,Zhang Y,Nan K,Liang X

更新日期：2017-05-01 00:00:00

abstract：:Wiskott-Aldrich syndrome protein family member 3 (WASF3) is required for invasion and metastasis in different cancer cell types, and has been demonstrated to possess prognostic value in various types of human cancer. However, to the best of our knowledge, the expression profile of WASF3 and its correlations with the c...

journal_title：Oncology letters

authors： Wu J,Wang GC,Chen XJ,Xue ZR

更新日期：2014-09-01 00:00:00

abstract：:The current report presents the case of a 41-year-old male exhibiting a giant cell tumor of the tendon sheath (GCT-TS) arising from the patellar tendon sheath. Plain radiography and magnetic resonance imaging revealed a well-localized mass that wrapped around the patellar tendon, and extended from the subcutis into th...

journal_title：Oncology letters

authors： Akahane T,Mori N,Yoshida K

更新日期：2014-12-01 00:00:00

abstract：:Wilms tumor (WT) is the most common pediatric renal malignancy. A recent ontogenic model suggests that undifferentiated tumor state, and hence poor prognosis, in WT is determined by stabilization of β-catenin in the nucleus. Forkhead box M1 (FOXM1) is a downstream component of the Wnt pathway and promotes nuclear loca...

journal_title：Oncology letters

authors： Apelt N,Hubertus J,Mayr D,Graf N,Furtwängler R,Von Schweinitz D,Kappler R

更新日期：2016-10-01 00:00:00

abstract：:Natural products are a promising source for the development of novel cancer therapies, due to their potential effectiveness and low toxicity profiles. As a main component of Herba oxytropis, 2',4'-dihydroxychalcone (TFC) is known to demonstrate anti-tumor activity in vitro. In the present study, TFC was found to potent...

journal_title：Oncology letters

authors： Sheng Y,Zou M,Wang Y,Li Q

更新日期：2015-12-01 00:00:00

abstract：:Central nervous system-based cancers have a much higher mortality rate with the 2016 estimates at 6.4 for incidence and 4.3 for deaths per 100,000 individuals. Grade IV astrocytomas, known as glioblastomas are highly aggressive and show a high proliferation index, diffused infiltration, angiogenesis, microvascular pro...

journal_title：Oncology letters

authors： Huang WJ,Chen WW,Zhang X

更新日期：2016-10-01 00:00:00

abstract：:Spontaneous remission (SR) in acute lymphoblastic leukemia (ALL) is a rare phenomenon, but the disease course and its underlying processes are of basic and clinical interest. Herein is reported the case of a pregnant, 31-year-old patient who developed ALL, followed by septic shock and SR of ALL. Information is summari...

journal_title：Oncology letters

authors： Höres T,Wendelin K,Schaefer-Eckart K

更新日期：2018-01-01 00:00:00

abstract：:The present study reviewed three patients with acute myeloid leukemia (AML) who had the specific genetic abnormality t(16;21)(p11;q22). To investigate the clinical and laboratory characteristics of AML with t(16;21)(p11;q22) translocation, the similarities and differences of clinical characteristics and laboratory exa...

journal_title：Oncology letters

authors： Zhang Z,Zou J,Li Y,Liu Z,Xu R,Tian W,Zhao Z,Sun H,Han J,Wang J,Zhang B,Ju Y

更新日期：2015-05-01 00:00:00

abstract：:AR-42 is a member of a novelly discovered class of phenylbutyrate-derived histone deacetylase inhibitors, and has a number of antitumor effects in a variety of tumor types; however, the role of AR-42 and its possible mechanisms have not been reported in the treatment of breast cancer. The aim of the present study was ...

journal_title：Oncology letters

authors： Zhou R,Wu J,Tang X,Wei X,Ju C,Zhang F,Sun J,Shuai D,Zhang Z,Liu Q,Lv XB

更新日期：2018-08-01 00:00:00

abstract：:An elevated neutrophil to lymphocyte ratio (NLR) has been reported to be associated with the pathological response to neoadjuvant therapies in numerous types of cancer. The aim of the current study was to clarify the association between pre-treatment NLR and the pathological response to preoperative chemoradiotherapy ...

journal_title：Oncology letters

authors： Hasegawa S,Eguchi H,Tomokuni A,Tomimaru Y,Asaoka T,Wada H,Hama N,Kawamoto K,Kobayashi S,Marubashi S,Konnno M,Ishii H,Mori M,Doki Y,Nagano H

更新日期：2016-02-01 00:00:00

abstract：:To determine the radiosensitizing effect of apatinib on esophageal cancer cells, and to preliminarily investigate the underlying mechanism, KYSE-150 cells were treated with apatinib, x-ray or apatinib combined with x-ray, and compared with a blank control. It was observed that apatinib significantly inhibited vascular...

journal_title：Oncology letters

authors： Hu L,Sun F,Sun Z,Ni X,Wang J,Wang J,Zhou M,Feng Y,Kong Z,Hua Q,Yu J

更新日期：2019-02-01 00:00:00