Abstract:
:The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in multicenter clinical trials conducted in China. The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People's Republic of China for treatment of COVID-19 infection in larger populations in the future.
journal_name
Biosci Trendsjournal_title
Bioscience trendsauthors
Gao J,Tian Z,Yang Xdoi
10.5582/bst.2020.01047subject
Has Abstractpub_date
2020-03-16 00:00:00pages
72-73issue
1eissn
1881-7815issn
1881-7823journal_volume
14pub_type
杂志文章abstract::The purpose of the present study was to evaluate whether pulse pressure variation (PPV) and stroke volume variation (SVV) can predict fluid responsiveness in patients with intra-abdominal hypertension (IAH) in either a supine or Trendelenburg position. Forty mechanically ventilated patients that exhibited IAH resultin...
journal_title:Bioscience trends
pub_type: 临床试验,杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::Audiological characteristics were investigated in 81 ears of 53 infants with abnormal transient evoked otoacoustic emission (TEOAE) and normal auditory brainstem response (ABR). The relationship between ABR and other hearing testing methods, including 40Hz auditory event-related potential (40Hz-AERP), auditory steady ...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2008-10-01 00:00:00
abstract::To determine the feasibility of using a nanoparticle immunoassay for clinical therapeutic drug monitoring (TDM) of docetaxel concentrations, a sensitive and simple method of liquid chromatography-tandem mass spectrometry (LC-MS/MS) was established to measure the docetaxel concentration in human plasma and the results ...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01029
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2019.01191
更新日期:2019-11-13 00:00:00
abstract::The present observational study aimed to clarify the relationship between the tip position of an indwelling venous catheter and the subcutaneous edema using ultrasonography images. Data were obtained before catheter removal in a medical ward of a university hospital in Tokyo, Japan. Two hundred peripheral intravenous ...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2015.01114
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abstract::Adjuvant therapy after resection of hepatocellular carcinoma (HCC) is limited. Here, we evaluated the effects of postoperative sorafenib on recurrence and survival in HCC patients. Recurrence-free survival and overall survival were analyzed as the main endpoint, recurrence rate, and mortality rate were analyzed as sec...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2014.01120
更新日期:2014-12-01 00:00:00
abstract::The present study investigated the effect of the VEGF165 gene on adhesion, migration, and proliferation of endothelial progenitor cells (EPCs) derived from peripheral blood of rabbits. Peripheral blood mononuclear cells were isolated from rabbits by density gradient centrifugation with Ficoll-Plaque Plus. EPCs were ch...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2012.v6.5.270
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abstract::The dominant-negative inhibition of KCNJ2-encoded inward rectifier potassium channels (Kir2) is currently considered the best approach to biological pacemakers. We hypothesized that inhibition of the inward rectifier potassium current (IK1) in ventricular myocytes by RNA interference (RNAi) would convert ventricular m...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2012.v6.1.26
更新日期:2012-02-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章,评审
doi:10.5582/bst.2017.01056
更新日期:2017-07-24 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2015.01172
更新日期:2016-02-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2020.03180
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2010-02-01 00:00:00
abstract::The effects of anesthesia with sevoflurane and with propofol on glucose utilization in rats were investigated. Sevoflurane significantly impairs glucose utilization whereas propofol does not. Both insulin secretion and sensitivity affect glucose utilization. Propofol is hydrophobic, and anesthesia with this agent is a...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2014.01060
更新日期:2014-06-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01187
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.8.126
更新日期:2014-04-01 00:00:00
abstract::The mortality rate of fulminant hepatic failure was high until liver transplantation was presented as a potential therapy. We encountered a patient with hyperacute fulminant hepatic failure due to hepatitis B virus infection. Living donor liver transplantation was planned but abandoned because her brain edema progress...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2007-08-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01111
更新日期:2017-11-20 00:00:00
abstract::Malignant pericardial effusion is one of the severe complications in advanced lung cancer patients, seriously affecting the patient's cardiopulmonary function and even life. Pericardial drainage and instillation of anti-neoplastic drugs in the pericardial cavity seems to offer the best chance of controlling pericardia...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2014.01073
更新日期:2014-08-01 00:00:00
abstract::The aim of the current study was to investigate the effects of FL118, a novel camptothecin analogue, on migration and invasion of human breast cancer cells and the underlying mechanisms of those effects. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and a plate clone formation assay we...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01288
更新日期:2018-01-01 00:00:00
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journal_title:Bioscience trends
pub_type: 临床试验,杂志文章
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abstract::In-stent restenosis is highly related to the deposition of inflammatory extracellular matrix and the migration of endothelial and vascular smooth muscle cells. The miR-17/TIMP-1/interleukin pathway regulates vascular matrix remodeling and plays an important role in the inflammatory reaction. This study identified miR-...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2019.01274
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journal_title:Bioscience trends
pub_type: 杂志文章
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01211
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journal_title:Bioscience trends
pub_type: 杂志文章
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01240
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2012-04-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
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