Traditional Chinese medicine for human papillomavirus (HPV) infections: A systematic review.

Abstract:

:Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been a handful of treatments for HPV-associated benign or malignant diseases, traditional Chinese medicine being one of them. This systematic review focuses on the application of traditional Chinese medicine in HPV infection and related diseases on the basis of clinical findings. Moreover it covers compositions and mechanisms based on in vitro laboratory methods and animal models. Traditional Chinese medicine improves clinical index in the treatment of cervical cancer and genital warts; the mechanisms behind the effectiveness might be the regulation of cell apoptosis, viral gene transcription and translation, cell signal transduction pathways, and immune function.

journal_name

Biosci Trends

journal_title

Bioscience trends

authors

Lin J,Chen L,Qiu X,Zhang N,Guo Q,Wang Y,Wang M,Gober HJ,Li D,Wang L

doi

10.5582/bst.2017.01056

subject

Has Abstract

pub_date

2017-07-24 00:00:00

pages

267-273

issue

3

eissn

1881-7815

issn

1881-7823

journal_volume

11

pub_type

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