Trends in the use of preconditioning to hypoxia for early prevention of future life diseases.

abstract：:Malignant pericardial effusion is one of the severe complications in advanced lung cancer patients, seriously affecting the patient's cardiopulmonary function and even life. Pericardial drainage and instillation of anti-neoplastic drugs in the pericardial cavity seems to offer the best chance of controlling pericardia...

journal_title：Bioscience trends

authors： Sun T,Zhang Y,Shen Y,Hu K,Zuo M

更新日期：2014-08-01 00:00:00

abstract：:The present observational study aimed to clarify the relationship between the tip position of an indwelling venous catheter and the subcutaneous edema using ultrasonography images. Data were obtained before catheter removal in a medical ward of a university hospital in Tokyo, Japan. Two hundred peripheral intravenous ...

journal_title：Bioscience trends

authors： Murayama R,Takahashi T,Tanabe H,Yabunaka K,Oe M,Oya M,Uchida M,Komiyama C,Sanada H

更新日期：2015-12-01 00:00:00

abstract：:Information about the muscarinic receptor subtype(s) mediating pulmonary circulatory vasodilator responses to acetylcholine (ACh) is limited. The aim of this study was to pharmacologically characterize the muscarinic receptors associated with ACh-induced pulmonary vasodilation in a pulmonary hypertension model. Vasodi...

journal_title：Bioscience trends

authors： Orii R,Sugawara Y,Sawamura S,Yamada Y

更新日期：2010-10-01 00:00:00

abstract：:The current study retrospectively investigated variations in audiological phenotypes in children with GJB2 gene mutations. Subjects were 128 infants and young children who were seen as outpatients by Otology at Beijing Tongren Hospital from 2012 to 2018. Of the 128 subjects, 99 had biallelic truncating (T/T) mutations...

journal_title：Bioscience trends

authors： Wang X,Huang L,Zhao X,Wang X,Cheng X,Du Y,Liu D

更新日期：2018-09-19 00:00:00

abstract：:Transplantation with Wharton's jelly derived mesenchymal stem cells (WJ-MSCs) showed great benefits for restoring myocardial function. However, the outcome of WJ-MSCs transplantation was unsuccessful due to multiple factors including oxidative damage. The presence of oxidative stress due to myocardium injury influence...

journal_title：Bioscience trends

authors： Nimsanor N,Phetfong J,Kitiyanant N,Kamprom W,Supokawej A

更新日期：2019-11-13 00:00:00

abstract：:Previous studies demonstrated that miR-15a-5p was probably associated with human hepatocellular carcinoma, while the function of miR-15a-5p in OA (Osteoarthritis) still remains unknown. Here, we uncovered the potential role of miR-15a-5p on OA pathogenesis and confirmed its predicted target VEGFA (Vascular Endothelial...

journal_title：Bioscience trends

authors： Chen H,Tian Y

更新日期：2017-01-16 00:00:00

abstract：:Once-daily tacrolimus (denoted here simply as OD) is a recently developed extended release drug formulation. The purpose of the present study was to pharmacokinetically evaluate tacrolimus exposure and determine the feasibility of its de novo use in liver transplant recipients in the perioperative period. This was an ...

journal_title：Bioscience trends

authors： Sugawara Y,Miyata Y,Kaneko J,Tamura S,Aoki T,Sakamoto Y,Hasegawa K,Yamashiki N,Kokudo N

更新日期：2011-08-01 00:00:00

abstract：:Since the first outbreak of human infection with avian influenza A (H7N9) virus was identified in 2013, five seasonal outbreaks have occurred in China. The fifth outbreak started earlier than usual. A sudden increase in cases of human infection with avian influenza A (H7N9) virus has been reported in China since Septe...

journal_title：Bioscience trends

authors： Shen Y,Lu H

更新日期：2017-03-22 00:00:00

abstract：:Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been...

journal_title：Bioscience trends

authors： Lin J,Chen L,Qiu X,Zhang N,Guo Q,Wang Y,Wang M,Gober HJ,Li D,Wang L

更新日期：2017-07-24 00:00:00

abstract：:Hepatitis B induced by hepatitis B virus (HBV) remains a major public health problem worldwide. Although several antiviral drugs have been approved for hepatitis B, they cause significant dose-dependent side-effects (interferon-alpha) and drug resistance (lamivudine, etc.). Safe and potent new anti-HBV drugs are urgen...

journal_title：Bioscience trends

authors： Cui X,Wang Y,Kokudo N,Fang D,Tang W

更新日期：2010-04-01 00:00:00

abstract：:Human serum albumin (HSA) is used as an important plasma volume expander in clinical practice. In the present study, HSA was N-terminally PEGylated and a PEGylated HAS (PEG-HSA) carrying one chain of PEG (20 kDa) per HSA molecule was obtained. The purity, secondary structure and hydrodynamic radius of the modified pro...

journal_title：Bioscience trends

authors： Zhao T,Yang Y,Zong A,Tan H,Song X,Meng S,Song C,Pang G,Wang F

更新日期：2012-04-01 00:00:00

abstract：:Benign portal vein stenosis is a rare complication following pancreaticoduodenectomy. Because a direct surgical approach to the portal vein is difficult due to severe adhesions following pancreaticoduodenectomy, portal vein stent placement is considered a good treatment option. Herein, we report 3 cases of severe port...

journal_title：Bioscience trends

authors： Sawai Y,Kokudo T,Sakamoto Y,Takao H,Kazami Y,Nishioka Y,Akamatsu N,Arita J,Kaneko J,Hasegawa K

更新日期：2019-01-22 00:00:00

abstract：:Information about medical students' choice of specialty can be helpful for planning health manpower. However, such information from medical students in Malaysian medical schools is lacking. We carried out a cross-sectional questionnaire survey among fourth- and fifth-year medical undergraduate students at Melaka-Manip...

journal_title：Bioscience trends

authors： Chew YW,Rajakrishnan S,Low CA,Jayapalan PK,Sreeramareddy CT

更新日期：2011-01-01 00:00:00

abstract：:Audiological characteristics were investigated in 81 ears of 53 infants with abnormal transient evoked otoacoustic emission (TEOAE) and normal auditory brainstem response (ABR). The relationship between ABR and other hearing testing methods, including 40Hz auditory event-related potential (40Hz-AERP), auditory steady ...

journal_title：Bioscience trends

authors： Huang L,Han D,Guo Y,Liu S,Cui X,Mo L,Qi B,Cai Z,Liu H,En H,Guo L

更新日期：2008-10-01 00:00:00

abstract：:Precise diagnosis is a key measurement for malaria control and elimination, traditional microscopy and rapid diagnostic tests cannot satisfy the requirements especially in the low transmission endemic areas or in the malaria elimination phase. Polymerase chain reaction (PCR) with high sensitivity and specificity can b...

journal_title：Bioscience trends

authors： Yin J,Li M,Yan H,Zhou S

更新日期：2018-01-01 00:00:00

abstract：:Obesity has become a severe public health problem worldwide. Crocin, a natural product, has been reported to have a number of pharmacological activities, including anti-inflammatory, anti-cancer, neuroprotective, antihypertensive, and cardioprotective action. The aims of the current study were to identify the benefici...

journal_title：Bioscience trends

authors： Gu M,Luo L,Fang K

更新日期：2018-01-01 00:00:00

abstract：:At the end of 2013, a Japanese newspaper reported that 4,173 children were unidentified or missing in Japan. The article concluded that child abuse was a matter of national concern. In examining the strengths and weaknesses of Japan's welfare system in regard to child abuse, it would seem that a weakness exists with r...

journal_title：Bioscience trends

authors： Takahashi K,Kanda H,Sugaya N

更新日期：2014-08-01 00:00:00

abstract：:The effects of anesthesia with sevoflurane and with propofol on glucose utilization in rats were investigated. Sevoflurane significantly impairs glucose utilization whereas propofol does not. Both insulin secretion and sensitivity affect glucose utilization. Propofol is hydrophobic, and anesthesia with this agent is a...

journal_title：Bioscience trends

authors： Li X,Kitamura T,Kawamura G,Mori Y,Sato K,Araki Y,Sato R,Yamada Y

更新日期：2014-06-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an insidious, lethal asbestos-related cancer that is poorly responsive to current treatments. Specific and sensitive biomarkers providing early MM diagnosis in exposed subjects, who are at high-risk of developing it, are sorely needed. MicroRNAs (miRNAs) are endogenous, non-coding, small...

journal_title：Bioscience trends

authors： Micolucci L,Rippo MR,Olivieri F,Procopio AD

更新日期：2017-03-22 00:00:00

abstract：:The maternal mortality ratio in Laos in 2005 was 660 per 100,000 lives birth which was the third highest in Asia-Pacific Region. The objective was to determine the availability and use of emergency obstetric care (EmOC) in provincial and district hospitals in Borikhamxay, Khammouane, and Savannakhet provinces using UN...

journal_title：Bioscience trends

authors： Douangphachanh X,Ali M,Outavong P,Alongkon P,Sing M,Chushi K

更新日期：2010-12-01 00:00:00

abstract：:In oocytes, many maternally supplied products are stored, and these products play important roles in cell cycle regulation and early development. Mos protein, which is coded on the c-mos gene, promotes oocyte maturation and is involved in MAP-kinase signaling pathway. In Xenopus, maternally supplied c-mos mRNA undergo...

journal_title：Bioscience trends

authors： Suzuki H,Tsukahara T,Inoue K

更新日期：2009-06-01 00:00:00

abstract：:Whether radioactive iodine treatment of Graves' disease (GD) during pregnancy will increase pregnancy loss and affect fetal development is still a matter of concern. From May 2005 to December 2015, 2,276 childbearing-age women with GD received iodine-131 treatment in our departments and were retrospectively enrolled i...

journal_title：Bioscience trends

authors： Guan L,Chen G,Zhang J,Wang L

更新日期：2016-09-05 00:00:00

abstract：:In patients at risk of hepatocarcinogenesis, tumors are frequently detected with atypical radiological patterns related to hepatocellular carcinoma (HCC) on imaging studies. Despite their high potential for malignancy, whether to resect such lesions immediately is controversial. Based on histological findings, patient...

journal_title：Bioscience trends

authors： Higaki T,Midorikawa Y,Nakashima Y,Nakayama H,Matsuoka S,Moriyama M,Sugitani M,Takayama T

更新日期：2017-07-24 00:00:00

abstract：:The mortality rate of fulminant hepatic failure was high until liver transplantation was presented as a potential therapy. We encountered a patient with hyperacute fulminant hepatic failure due to hepatitis B virus infection. Living donor liver transplantation was planned but abandoned because her brain edema progress...

journal_title：Bioscience trends

authors： Takemura N,Sugawara Y,Tamura S,Kakeno J,Matsui Y,Makuuchi M

更新日期：2007-08-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is shown to have apparent efficacy and acceptable safety against COVID-19 associated pneumonia in mul...

journal_title：Bioscience trends

authors： Gao J,Tian Z,Yang X

更新日期：2020-03-16 00:00:00

abstract：:Granzyme 3 (Gr3) is known as a tryptase-type member of the granzyme family and exists in the granules of immunocompetent cells. Granule proteases including granzymes, are transported into the cytoplasm of tumor cells or virus-infected cells by perforin function, degrade cytoplasmic or nuclear proteins and subsequently...

journal_title：Bioscience trends

authors： Hirata Y,Inagaki H,Shimizu T,Kawada T

更新日期：2014-04-01 00:00:00

abstract：:Aster yomena (Kitam.) Honda has been widely used as a traditional herbal medicine for centuries to treat cough, asthma, insect bites, etc. Recent reports indicate that A. yomena possesses a wide spectrum of pharmacological activities; however, few experiments have described its anti-inflammatory properties. The presen...

journal_title：Bioscience trends

authors： Kang HJ,Jeong JS,Park NJ,Go GB,Kim SO,Park C,Kim BW,Hong SH,Choi YH

更新日期：2017-03-22 00:00:00

abstract：:Human herpesvirus 8 (HHV8) is an important opportunistic infection of HIV/AIDS. However, very little is known about antibody seropositivities to HHV8 lytic and latent antigens among HIV-infected patients in China. Therefore, a cross-sectional study was conducted to explore HHV8 serostatus among 316 HIV-infected patien...

journal_title：Bioscience trends

authors： Zhang TJ,He N,Ding YY,Jiang QW,Wood C

更新日期：2012-06-01 00:00:00

abstract：:The initial processes involved in radiation carcinogenesis have not been clearly elucidated. We isolated mouse mutant cells exhibiting plasticity in their mutation phenotypes. These mutant cells were originally isolated from an irradiated cell population as 6-thioguanine resistant (6TGR) mutants that were deficient in...

journal_title：Bioscience trends

authors： Yamauchi M,Fukutsu K,Sakagami M,Yamada Y

更新日期：2010-08-01 00:00:00

abstract：:Cardiomyocyte nutrient deprivation is a common clinical event that mediates various cardiac ischemic processes and is associated with autophagy activation and cell survival or death. Luteolin-7-O-glucoside (LUTG) was one of the flavonoid glycosides isolated from Dracocephalum tanguticum. Previous research had showed t...

journal_title：Bioscience trends

authors： Yao H,Zhou L,Tang L,Guan Y,Chen S,Zhang Y,Han X

更新日期：2017-11-20 00:00:00