Global concern regarding the fifth epidemic of human infection with avian influenza A (H7N9) virus in China.

abstract：:Information about medical students' choice of specialty can be helpful for planning health manpower. However, such information from medical students in Malaysian medical schools is lacking. We carried out a cross-sectional questionnaire survey among fourth- and fifth-year medical undergraduate students at Melaka-Manip...

journal_title：Bioscience trends

authors： Chew YW,Rajakrishnan S,Low CA,Jayapalan PK,Sreeramareddy CT

更新日期：2011-01-01 00:00:00

abstract：:The present study investigated the effect of the VEGF165 gene on adhesion, migration, and proliferation of endothelial progenitor cells (EPCs) derived from peripheral blood of rabbits. Peripheral blood mononuclear cells were isolated from rabbits by density gradient centrifugation with Ficoll-Plaque Plus. EPCs were ch...

journal_title：Bioscience trends

authors： Gu X,Miao X,Xu J,Cao J

更新日期：2012-10-01 00:00:00

abstract：:Atrazine (ATR), one of the most widely used herbicides worldwide, has caused a series of toxicological and environmental problems. This study sought to investigate the effects of ATR on the immune system of mice. Four-week-old female C57B l/6 mice were treated with 5, 25, and 125 mg/kg ATR for 28 days. On day 29, bloo...

journal_title：Bioscience trends

authors： Zhao S,Liu J,Zhao F,Liu W,Li N,Suo Q,Zhao J,Zhao L

更新日期：2013-08-01 00:00:00

abstract：:It has been hypothesized that subjective well-being (SWB) is determined by a combination of individual characteristics, social environment, and physical environment. However, few studies have simultaneously examined the relationships of the social and physical attributes of a neighborhood with SWB. Accordingly, the pr...

journal_title：Bioscience trends

authors： Gao J,Weaver SR,Fu H,Jia Y,Li J

更新日期：2017-11-20 00:00:00

abstract：:A research project involving sheets of retinal pigment epithelium constructed from iPS cells derived from patients with age-related maculopathy is one step closer to being approved for clinical trials by the Japanese Government. Now is the time to make therapies using iPS cells clinically available. ...

journal_title：Bioscience trends

authors： Song P,Inagaki Y,Sugawara Y,Kokudo N

更新日期：2013-06-01 00:00:00

abstract：:Our purpose was to explore the remission of insulin resistance after bariatric surgery to discover the mechanism of diabetes remission excluding dietary factors. A retrospective case control study was conducted on patients with type 2 diabetes, who underwent laparoscopic sleeve gastrectomy (LSG) or laparoscopic gastri...

journal_title：Bioscience trends

authors： Zhu Y,Sun Z,Du Y,Xu G,Gong K,Zhu B,Zhang N

更新日期：2017-01-01 00:00:00

abstract：:We have recently demonstrated that unconjugated bilirubin (UCB) limits the overexpression of adhesion molecules and inhibits the PMN endothelial adhesion induced by the pro-inflammatory cytokine TNFalpha. To understand the molecular events involved we investigated whether the inhibitory effect is determined by a direc...

journal_title：Bioscience trends

authors： Mazzone GL,Rigato I,Ostrow JD,Tiribelli C

更新日期：2009-08-01 00:00:00

abstract：:Aster yomena (Kitam.) Honda has been widely used as a traditional herbal medicine for centuries to treat cough, asthma, insect bites, etc. Recent reports indicate that A. yomena possesses a wide spectrum of pharmacological activities; however, few experiments have described its anti-inflammatory properties. The presen...

journal_title：Bioscience trends

authors： Kang HJ,Jeong JS,Park NJ,Go GB,Kim SO,Park C,Kim BW,Hong SH,Choi YH

更新日期：2017-03-22 00:00:00

abstract：:Malignant mesothelioma (MM) is an insidious, lethal asbestos-related cancer that is poorly responsive to current treatments. Specific and sensitive biomarkers providing early MM diagnosis in exposed subjects, who are at high-risk of developing it, are sorely needed. MicroRNAs (miRNAs) are endogenous, non-coding, small...

journal_title：Bioscience trends

authors： Micolucci L,Rippo MR,Olivieri F,Procopio AD

更新日期：2017-03-22 00:00:00

abstract：:The effects of anesthesia with sevoflurane and with propofol on glucose utilization in rats were investigated. Sevoflurane significantly impairs glucose utilization whereas propofol does not. Both insulin secretion and sensitivity affect glucose utilization. Propofol is hydrophobic, and anesthesia with this agent is a...

journal_title：Bioscience trends

authors： Li X,Kitamura T,Kawamura G,Mori Y,Sato K,Araki Y,Sato R,Yamada Y

更新日期：2014-06-01 00:00:00

abstract：:Spontaneous esophageal perforation (Boerhaave's syndrome) is an uncommon and challenging condition with significant morbidity and mortality. Surgical treatment is indicated in the large majority of cases and different procedures have been described in this respect. We present the results of a mono-institutional evalua...

journal_title：Bioscience trends

authors： Pezzetta E,Kokudo T,Uldry E,Yamaguchi T,Kudo H,Ris HB,Christodoulou M,Vuilleumier H,Halkic N

更新日期：2016-05-23 00:00:00

abstract：:Bu-Shen-Ning-Xin decoction (BSNXD), a traditional Chinese medicine, has been used to prevent and treat age-related diseases such as postmenopausal osteoporosis (PMO) for decades. This study sought to investigate the underlying mechanisms of BSNXD in terms of receptor activation of nuclear factor κB ligand (RANKL)-indu...

journal_title：Bioscience trends

authors： Gui Y,Qiu X,Xu Y,Li D,Wang L

更新日期：2015-06-01 00:00:00

abstract：:The aim of this study is to compare the efficacy of endoluminal ultrasonography (EUS) and spiral computerized tomography (SCT) in preoperative local staging of rectal carcinoma. EUS and SCT were performed prior to surgery in 78 patients with rectal carcinoma. After radical surgery, the preoperative findings were compa...

journal_title：Bioscience trends

authors： Ju H,Xu D,Li D,Chen G,Shao G

更新日期：2009-04-01 00:00:00

abstract：:We construct and validate a non-invasive clinical scoring model to predict mortality in HIV/TB patients at end stage of AIDS in China. There were 1,007 HIV/TB patients admitted to Beijing Ditan Hospital from August 2009 to January 2018 included in this study, who were randomly assigned to form derivation cohort and va...

journal_title：Bioscience trends

authors： Zhang Z,Xu L,Pang X,Zeng Y,Hao Y,Wang Y,Wu L,Gao G,Yang D,Zhao H,Xiao J

更新日期：2019-05-12 00:00:00

abstract：:This study is an extension of the previous enhancement of dissolution properties of repaglinide using liquisolid compacts. The development and validation of a highperformance liquid chromatography (HPLC) assay for the determination of repaglinide concentration in rabbit plasma for pharmacokinetic studies is described....

journal_title：Bioscience trends

authors： El-Houssieny BM,Wahman L,Arafa NM

更新日期：2010-02-01 00:00:00

abstract：:The purpose of the present study was to evaluate whether pulse pressure variation (PPV) and stroke volume variation (SVV) can predict fluid responsiveness in patients with intra-abdominal hypertension (IAH) in either a supine or Trendelenburg position. Forty mechanically ventilated patients that exhibited IAH resultin...

journal_title：Bioscience trends

authors： Liu X,Fu Q,Mi W,Liu H,Zhang H,Wang P

更新日期：2013-04-01 00:00:00

abstract：:Once-daily tacrolimus (denoted here simply as OD) is a recently developed extended release drug formulation. The purpose of the present study was to pharmacokinetically evaluate tacrolimus exposure and determine the feasibility of its de novo use in liver transplant recipients in the perioperative period. This was an ...

journal_title：Bioscience trends

authors： Sugawara Y,Miyata Y,Kaneko J,Tamura S,Aoki T,Sakamoto Y,Hasegawa K,Yamashiki N,Kokudo N

更新日期：2011-08-01 00:00:00

abstract：:Cardiomyocyte nutrient deprivation is a common clinical event that mediates various cardiac ischemic processes and is associated with autophagy activation and cell survival or death. Luteolin-7-O-glucoside (LUTG) was one of the flavonoid glycosides isolated from Dracocephalum tanguticum. Previous research had showed t...

journal_title：Bioscience trends

authors： Yao H,Zhou L,Tang L,Guan Y,Chen S,Zhang Y,Han X

更新日期：2017-11-20 00:00:00

abstract：:The aim of the current study was to investigate the effects of FL118, a novel camptothecin analogue, on migration and invasion of human breast cancer cells and the underlying mechanisms of those effects. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and a plate clone formation assay we...

journal_title：Bioscience trends

authors： Yang Z,Ji L,Jiang G,Liu R,Liu Z,Yang Y,Ma Q,Zhao H

更新日期：2018-01-01 00:00:00

abstract：:Information about the muscarinic receptor subtype(s) mediating pulmonary circulatory vasodilator responses to acetylcholine (ACh) is limited. The aim of this study was to pharmacologically characterize the muscarinic receptors associated with ACh-induced pulmonary vasodilation in a pulmonary hypertension model. Vasodi...

journal_title：Bioscience trends

authors： Orii R,Sugawara Y,Sawamura S,Yamada Y

更新日期：2010-10-01 00:00:00

abstract：:Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Antibiotic resistance is rising to dangerously high levels in all parts of the world, leading to higher medical costs, prolonged hospital stays, and inc...

journal_title：Bioscience trends

authors： Tang Q,Song P,Li J,Kong F,Sun L,Xu L

更新日期：2016-02-01 00:00:00

abstract：:The purpose of this study was to evaluate the 2-day seminar in 2 consecutive years respectively for community health professionals. We prepared the child-rearing support manual (CRSM) and conducted a seminar program to improve skills to provide mental assessments and postnatal care support for mothers and their famili...

journal_title：Bioscience trends

authors： Kamibeppu K,Furuta M,Yamashita H,Sugishita K,Suzumiya H,Yoshida K

更新日期：2009-02-01 00:00:00

abstract：:In all malignant diseases, several clinical and histopathological tests are established as standard methods for diagnosis. Alternative diagnostic quantitative methods are still lacking or conflicting in cancer of the cervix. Although DNA analysis was one of the earliest applications in flow cytometry and the DNA conte...

journal_title：Bioscience trends

authors： Chhavi,Saxena M,Negi MP,Singh S,Singh PK,Singh U,Bhatt ML

更新日期：2010-06-01 00:00:00

abstract：:In-stent restenosis is highly related to the deposition of inflammatory extracellular matrix and the migration of endothelial and vascular smooth muscle cells. The miR-17/TIMP-1/interleukin pathway regulates vascular matrix remodeling and plays an important role in the inflammatory reaction. This study identified miR-...

journal_title：Bioscience trends

authors： Jiang F,Zhang X,Lu YM,Li YG,Zhou X,Wang YS

更新日期：2019-11-13 00:00:00

abstract：:Tissue engineering has been one of the most promising strategies for the regeneration of impaired tissue. Application of three-dimensional porous scaffolds has greatly improved the outcome of tissue engineering in many categories. Cell seeding is one of the key issues in tissue regeneration. It depends not only on the...

journal_title：Bioscience trends

authors： Dai W,Dong J,Chen G,Uemura T

更新日期：2009-12-01 00:00:00

abstract：:Inflammation-based markers are considered prognostic indicators for patients with hepatocellular carcinoma (HCC) after liver resection. However, there is little information concerning whether they are useful for HCC patients with clinically significant portal hypertension (CSPH). In this study, 1452 patients were enro...

journal_title：Bioscience trends

authors： Qin L,Li C,Xie F,Wang Z,Wen T

更新日期：2020-09-21 00:00:00

abstract：:The current study retrospectively investigated variations in audiological phenotypes in children with GJB2 gene mutations. Subjects were 128 infants and young children who were seen as outpatients by Otology at Beijing Tongren Hospital from 2012 to 2018. Of the 128 subjects, 99 had biallelic truncating (T/T) mutations...

journal_title：Bioscience trends

authors： Wang X,Huang L,Zhao X,Wang X,Cheng X,Du Y,Liu D

更新日期：2018-09-19 00:00:00

abstract：:Recently, men who have sex with men (MSM) have become a population at high risk ofHIV infection in China, and more investigations of and intervention programs targeting this hidden population are urgently needed. The objective of this study was to assess the prevalence of HIV-positive individuals, HIV-related knowledg...

journal_title：Bioscience trends

authors： Tao X,Gai R,Zhang X,Zhang N,Zheng W,Xu A,Li S

更新日期：2008-06-01 00:00:00

abstract：:Dengue is an acute febrile illness resulting from infection by a flavivirus transmitted by the Aedes mosquito. It is characterized by bleeding manifestations and a plasma leak syndrome. Hepatic involvement in the form of elevation in transaminases is common. However, acute hepatic failure is uncommon. It is not known ...

journal_title：Bioscience trends

authors： Agarwal MP,Giri S,Sharma V,Roy U,Gharsangi K

更新日期：2011-01-01 00:00:00

abstract：:Complete loss of function in the WRN: RecQ3 DNA/RNA helicase gene causes Werner Syndrome (WS). WS patients with genetic instability manifest an early onset of age-related diseases including diabetes mellitus (DM), osteoporosis, atherosclerosis, and malignancy as well as early death. In 1,420 patients, WS was reported ...

journal_title：Bioscience trends

authors： Goto M

更新日期：2008-08-01 00:00:00