Performing laparoscopic surgery - Perspectives of young Chinese hepatobiliary surgeons.

abstract：:We construct and validate a non-invasive clinical scoring model to predict mortality in HIV/TB patients at end stage of AIDS in China. There were 1,007 HIV/TB patients admitted to Beijing Ditan Hospital from August 2009 to January 2018 included in this study, who were randomly assigned to form derivation cohort and va...

journal_title：Bioscience trends

authors： Zhang Z,Xu L,Pang X,Zeng Y,Hao Y,Wang Y,Wu L,Gao G,Yang D,Zhao H,Xiao J

更新日期：2019-05-12 00:00:00

abstract：:Information about medical students' choice of specialty can be helpful for planning health manpower. However, such information from medical students in Malaysian medical schools is lacking. We carried out a cross-sectional questionnaire survey among fourth- and fifth-year medical undergraduate students at Melaka-Manip...

journal_title：Bioscience trends

authors： Chew YW,Rajakrishnan S,Low CA,Jayapalan PK,Sreeramareddy CT

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study is to compare the efficacy of endoluminal ultrasonography (EUS) and spiral computerized tomography (SCT) in preoperative local staging of rectal carcinoma. EUS and SCT were performed prior to surgery in 78 patients with rectal carcinoma. After radical surgery, the preoperative findings were compa...

journal_title：Bioscience trends

authors： Ju H,Xu D,Li D,Chen G,Shao G

更新日期：2009-04-01 00:00:00

abstract：:Noninvasive prenatal testing (NIPT) is increasingly recognized and utilized in the antenatal care field. In the current study, we aimed to evaluate the clinical application and compare test outcomes of two generations of currently used NIPT techniques for detecting fetal chromosome abnormalities in a high-risk prenata...

journal_title：Bioscience trends

authors： Du Y,Lin J,Lan L,Dong Y,Zhu J,Jiang W,Pan X,Lu Y,Li D,Wang L

更新日期：2018-07-17 00:00:00

abstract：:Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Antibiotic resistance is rising to dangerously high levels in all parts of the world, leading to higher medical costs, prolonged hospital stays, and inc...

journal_title：Bioscience trends

authors： Tang Q,Song P,Li J,Kong F,Sun L,Xu L

更新日期：2016-02-01 00:00:00

abstract：:We identified the prevalence of depression and quality of life (QOL) of Japanese children with childhood cancer after discharge using the Birleson Depression Self-rating Scale for Children (DSRS-C) and the Pediatric Quality of Life Inventory (PedsQL). Subjects were 118 caregivers who raised children ages 2-18 with chi...

journal_title：Bioscience trends

authors： Wakimizu R,Hiraga N,Furuya K,Fukushima T,Tsuchida M,Koike K,Yamamoto T

更新日期：2011-12-01 00:00:00

abstract：:Adjuvant therapy after resection of hepatocellular carcinoma (HCC) is limited. Here, we evaluated the effects of postoperative sorafenib on recurrence and survival in HCC patients. Recurrence-free survival and overall survival were analyzed as the main endpoint, recurrence rate, and mortality rate were analyzed as sec...

journal_title：Bioscience trends

authors： Zhang W,Zhao G,Wei K,Zhang Q,Ma W,Song T,Wu Q,Zhang T,Kong D,Li Q

更新日期：2014-12-01 00:00:00

abstract：:Environmental factors during fetal life program the health outcomes regarding many diseases in future life. This idea has been supported by worldwide epidemiological studies, but the underlying mechanisms are still poorly understood. Three questions should be answered. (i) Does a common underlying cause of ordinary pa...

journal_title：Bioscience trends

authors： Basovich SN

更新日期：2013-02-01 00:00:00

abstract：:The present study investigated the effect of the VEGF165 gene on adhesion, migration, and proliferation of endothelial progenitor cells (EPCs) derived from peripheral blood of rabbits. Peripheral blood mononuclear cells were isolated from rabbits by density gradient centrifugation with Ficoll-Plaque Plus. EPCs were ch...

journal_title：Bioscience trends

authors： Gu X,Miao X,Xu J,Cao J

更新日期：2012-10-01 00:00:00

abstract：:To determine the feasibility of using a nanoparticle immunoassay for clinical therapeutic drug monitoring (TDM) of docetaxel concentrations, a sensitive and simple method of liquid chromatography-tandem mass spectrometry (LC-MS/MS) was established to measure the docetaxel concentration in human plasma and the results ...

journal_title：Bioscience trends

authors： Geng C,Li P,Chen X,Yuan G,Guo N,Liu H,Zhang R,Guo R

更新日期：2017-05-23 00:00:00

abstract：:Postmenopausal osteoporosis (PMO) has become a public health problem worldwide. Hormonal replacement therapy (HRT) is the most popular treatment for PMO at present, but the side effects, including increased risk of endometrial cancer and breast cancer, limit its clinical use. Therefore, finding a new medication with h...

journal_title：Bioscience trends

authors： Wu S,Zhao F,Zhao J,Li H,Chen J,Xia Y,Wang J,Zhao B,Zhao S,Li N

更新日期：2019-11-13 00:00:00

abstract：:Spontaneous esophageal perforation (Boerhaave's syndrome) is an uncommon and challenging condition with significant morbidity and mortality. Surgical treatment is indicated in the large majority of cases and different procedures have been described in this respect. We present the results of a mono-institutional evalua...

journal_title：Bioscience trends

authors： Pezzetta E,Kokudo T,Uldry E,Yamaguchi T,Kudo H,Ris HB,Christodoulou M,Vuilleumier H,Halkic N

更新日期：2016-05-23 00:00:00

abstract：:Complete loss of function in the WRN: RecQ3 DNA/RNA helicase gene causes Werner Syndrome (WS). WS patients with genetic instability manifest an early onset of age-related diseases including diabetes mellitus (DM), osteoporosis, atherosclerosis, and malignancy as well as early death. In 1,420 patients, WS was reported ...

journal_title：Bioscience trends

authors： Goto M

更新日期：2008-08-01 00:00:00

abstract：:Dengue is an acute febrile illness resulting from infection by a flavivirus transmitted by the Aedes mosquito. It is characterized by bleeding manifestations and a plasma leak syndrome. Hepatic involvement in the form of elevation in transaminases is common. However, acute hepatic failure is uncommon. It is not known ...

journal_title：Bioscience trends

authors： Agarwal MP,Giri S,Sharma V,Roy U,Gharsangi K

更新日期：2011-01-01 00:00:00

abstract：:Inflammation-based markers are considered prognostic indicators for patients with hepatocellular carcinoma (HCC) after liver resection. However, there is little information concerning whether they are useful for HCC patients with clinically significant portal hypertension (CSPH). In this study, 1452 patients were enro...

journal_title：Bioscience trends

authors： Qin L,Li C,Xie F,Wang Z,Wen T

更新日期：2020-09-21 00:00:00

abstract：:Hepatitis B induced by hepatitis B virus (HBV) remains a major public health problem worldwide. Although several antiviral drugs have been approved for hepatitis B, they cause significant dose-dependent side-effects (interferon-alpha) and drug resistance (lamivudine, etc.). Safe and potent new anti-HBV drugs are urgen...

journal_title：Bioscience trends

authors： Cui X,Wang Y,Kokudo N,Fang D,Tang W

更新日期：2010-04-01 00:00:00

abstract：:In patients at risk of hepatocarcinogenesis, tumors are frequently detected with atypical radiological patterns related to hepatocellular carcinoma (HCC) on imaging studies. Despite their high potential for malignancy, whether to resect such lesions immediately is controversial. Based on histological findings, patient...

journal_title：Bioscience trends

authors： Higaki T,Midorikawa Y,Nakashima Y,Nakayama H,Matsuoka S,Moriyama M,Sugitani M,Takayama T

更新日期：2017-07-24 00:00:00

abstract：:In oocytes, many maternally supplied products are stored, and these products play important roles in cell cycle regulation and early development. Mos protein, which is coded on the c-mos gene, promotes oocyte maturation and is involved in MAP-kinase signaling pathway. In Xenopus, maternally supplied c-mos mRNA undergo...

journal_title：Bioscience trends

authors： Suzuki H,Tsukahara T,Inoue K

更新日期：2009-06-01 00:00:00

abstract：:On October 25, 2018, the National Health Commission of China issued the National Essential Medicines List (2018 edition) [NEML (2018)]. The NEML (2018) contains 685 drugs, which consist of 417 chemicals and biological products and 268 Chinese patent medicines. Compared to the 2012 version of the NEML, a total number o...

journal_title：Bioscience trends

authors： He J,Tang M,Ye Z,Jiang X,Chen D,Song P,Jin C

更新日期：2018-01-01 00:00:00

abstract：:MLS128 is an anti-carbohydrate monoclonal antibody (mAb) that binds three or two consecutive Tn-antigens. MLS128 bound 110-210 kDa glycoproteins (GPs) and inhibited the growth of LS180 and HT29 colon and MCF-7 breast cancer cells. One possible mechanism of MLS128's inhibition of growth may be via insulin-like growth f...

journal_title：Bioscience trends

authors： Zamri N,Masuda N,Oura F,Yajima Y,Nakada H,Fujita-Yamaguchi Y

更新日期：2012-12-01 00:00:00

abstract：:Spinal cord injury (SCI) is a serious injury of the central nervous system and up until now there is no evident effective treatment for SCI. Axonal regeneration is the only way to restore functions after serious SCI that interrupt the long tracts mediating motor and sensory function. The hurdles for axonal regeneratio...

journal_title：Bioscience trends

authors： Cui X,Chen L,Ren Y,Ji Y,Liu W,Liu J,Yan Q,Cheng L,Sun YE

更新日期：2013-10-01 00:00:00

abstract：:The aim of the current study was to investigate the effects of FL118, a novel camptothecin analogue, on migration and invasion of human breast cancer cells and the underlying mechanisms of those effects. A 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and a plate clone formation assay we...

journal_title：Bioscience trends

authors： Yang Z,Ji L,Jiang G,Liu R,Liu Z,Yang Y,Ma Q,Zhao H

更新日期：2018-01-01 00:00:00

abstract：:Obesity has become a severe public health problem worldwide. Crocin, a natural product, has been reported to have a number of pharmacological activities, including anti-inflammatory, anti-cancer, neuroprotective, antihypertensive, and cardioprotective action. The aims of the current study were to identify the benefici...

journal_title：Bioscience trends

authors： Gu M,Luo L,Fang K

更新日期：2018-01-01 00:00:00

abstract：:A research project involving sheets of retinal pigment epithelium constructed from iPS cells derived from patients with age-related maculopathy is one step closer to being approved for clinical trials by the Japanese Government. Now is the time to make therapies using iPS cells clinically available. ...

journal_title：Bioscience trends

authors： Song P,Inagaki Y,Sugawara Y,Kokudo N

更新日期：2013-06-01 00:00:00

abstract：:The initial processes involved in radiation carcinogenesis have not been clearly elucidated. We isolated mouse mutant cells exhibiting plasticity in their mutation phenotypes. These mutant cells were originally isolated from an irradiated cell population as 6-thioguanine resistant (6TGR) mutants that were deficient in...

journal_title：Bioscience trends

authors： Yamauchi M,Fukutsu K,Sakagami M,Yamada Y

更新日期：2010-08-01 00:00:00

abstract：:Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been...

journal_title：Bioscience trends

authors： Lin J,Chen L,Qiu X,Zhang N,Guo Q,Wang Y,Wang M,Gober HJ,Li D,Wang L

更新日期：2017-07-24 00:00:00

abstract：:This meta-analysis aimed to review the regeneration rate of future liver remnant (FLR) and perioperative outcomes after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and two-stage hepatectomy (TSH). A web search was performed in "MEDLINE", "EMBASE", and "SCIENCE DIRECT" databases ...

journal_title：Bioscience trends

authors： Sun Z,Tang W,Sakamoto Y,Hasegawa K,Kokudo N

更新日期：2015-10-01 00:00:00

abstract：:Recently, men who have sex with men (MSM) have become a population at high risk ofHIV infection in China, and more investigations of and intervention programs targeting this hidden population are urgently needed. The objective of this study was to assess the prevalence of HIV-positive individuals, HIV-related knowledg...

journal_title：Bioscience trends

authors： Tao X,Gai R,Zhang X,Zhang N,Zheng W,Xu A,Li S

更新日期：2008-06-01 00:00:00

abstract：:Granzyme 3 (Gr3) is known as a tryptase-type member of the granzyme family and exists in the granules of immunocompetent cells. Granule proteases including granzymes, are transported into the cytoplasm of tumor cells or virus-infected cells by perforin function, degrade cytoplasmic or nuclear proteins and subsequently...

journal_title：Bioscience trends

authors： Hirata Y,Inagaki H,Shimizu T,Kawada T

更新日期：2014-04-01 00:00:00

abstract：:Catalpol is a natural iridoid glycoside with diverse bioactivities that is found in abundance in Rehmannia glutinosa Libosch. (Scrophulariaceae). The present study assessed whether catalpol treatment (5, 10, or 20 mg/kg for 14 days by intragastric administration (i.g.)) has an antidepressant-like effect on mice perfor...

journal_title：Bioscience trends

authors： Wang J,Cui Y,Feng W,Zhang Y,Wang G,Wang X,Zhou G

更新日期：2014-10-01 00:00:00