Pulse pressure variation and stroke volume variation predict fluid responsiveness in mechanically ventilated patients experiencing intra-abdominal hypertension.

abstract：:Recently, men who have sex with men (MSM) have become a population at high risk ofHIV infection in China, and more investigations of and intervention programs targeting this hidden population are urgently needed. The objective of this study was to assess the prevalence of HIV-positive individuals, HIV-related knowledg...

journal_title：Bioscience trends

authors： Tao X,Gai R,Zhang X,Zhang N,Zheng W,Xu A,Li S

更新日期：2008-06-01 00:00:00

abstract：:Postmenopausal osteoporosis (PMO) has become a public health problem worldwide. Hormonal replacement therapy (HRT) is the most popular treatment for PMO at present, but the side effects, including increased risk of endometrial cancer and breast cancer, limit its clinical use. Therefore, finding a new medication with h...

journal_title：Bioscience trends

authors： Wu S,Zhao F,Zhao J,Li H,Chen J,Xia Y,Wang J,Zhao B,Zhao S,Li N

更新日期：2019-11-13 00:00:00

abstract：:In-stent restenosis is highly related to the deposition of inflammatory extracellular matrix and the migration of endothelial and vascular smooth muscle cells. The miR-17/TIMP-1/interleukin pathway regulates vascular matrix remodeling and plays an important role in the inflammatory reaction. This study identified miR-...

journal_title：Bioscience trends

authors： Jiang F,Zhang X,Lu YM,Li YG,Zhou X,Wang YS

更新日期：2019-11-13 00:00:00

abstract：:Information about medical students' choice of specialty can be helpful for planning health manpower. However, such information from medical students in Malaysian medical schools is lacking. We carried out a cross-sectional questionnaire survey among fourth- and fifth-year medical undergraduate students at Melaka-Manip...

journal_title：Bioscience trends

authors： Chew YW,Rajakrishnan S,Low CA,Jayapalan PK,Sreeramareddy CT

更新日期：2011-01-01 00:00:00

abstract：:In patients at risk of hepatocarcinogenesis, tumors are frequently detected with atypical radiological patterns related to hepatocellular carcinoma (HCC) on imaging studies. Despite their high potential for malignancy, whether to resect such lesions immediately is controversial. Based on histological findings, patient...

journal_title：Bioscience trends

authors： Higaki T,Midorikawa Y,Nakashima Y,Nakayama H,Matsuoka S,Moriyama M,Sugitani M,Takayama T

更新日期：2017-07-24 00:00:00

abstract：:Audiological characteristics were investigated in 81 ears of 53 infants with abnormal transient evoked otoacoustic emission (TEOAE) and normal auditory brainstem response (ABR). The relationship between ABR and other hearing testing methods, including 40Hz auditory event-related potential (40Hz-AERP), auditory steady ...

journal_title：Bioscience trends

authors： Huang L,Han D,Guo Y,Liu S,Cui X,Mo L,Qi B,Cai Z,Liu H,En H,Guo L

更新日期：2008-10-01 00:00:00

abstract：:This study is an extension of the previous enhancement of dissolution properties of repaglinide using liquisolid compacts. The development and validation of a highperformance liquid chromatography (HPLC) assay for the determination of repaglinide concentration in rabbit plasma for pharmacokinetic studies is described....

journal_title：Bioscience trends

authors： El-Houssieny BM,Wahman L,Arafa NM

更新日期：2010-02-01 00:00:00

abstract：:The mortality rate of fulminant hepatic failure was high until liver transplantation was presented as a potential therapy. We encountered a patient with hyperacute fulminant hepatic failure due to hepatitis B virus infection. Living donor liver transplantation was planned but abandoned because her brain edema progress...

journal_title：Bioscience trends

authors： Takemura N,Sugawara Y,Tamura S,Kakeno J,Matsui Y,Makuuchi M

更新日期：2007-08-01 00:00:00

abstract：:The present study investigated the effect of the VEGF165 gene on adhesion, migration, and proliferation of endothelial progenitor cells (EPCs) derived from peripheral blood of rabbits. Peripheral blood mononuclear cells were isolated from rabbits by density gradient centrifugation with Ficoll-Plaque Plus. EPCs were ch...

journal_title：Bioscience trends

authors： Gu X,Miao X,Xu J,Cao J

更新日期：2012-10-01 00:00:00

abstract：:Previous studies demonstrated that miR-15a-5p was probably associated with human hepatocellular carcinoma, while the function of miR-15a-5p in OA (Osteoarthritis) still remains unknown. Here, we uncovered the potential role of miR-15a-5p on OA pathogenesis and confirmed its predicted target VEGFA (Vascular Endothelial...

journal_title：Bioscience trends

authors： Chen H,Tian Y

更新日期：2017-01-16 00:00:00

abstract：:A research project involving sheets of retinal pigment epithelium constructed from iPS cells derived from patients with age-related maculopathy is one step closer to being approved for clinical trials by the Japanese Government. Now is the time to make therapies using iPS cells clinically available. ...

journal_title：Bioscience trends

authors： Song P,Inagaki Y,Sugawara Y,Kokudo N

更新日期：2013-06-01 00:00:00

abstract：:In oocytes, many maternally supplied products are stored, and these products play important roles in cell cycle regulation and early development. Mos protein, which is coded on the c-mos gene, promotes oocyte maturation and is involved in MAP-kinase signaling pathway. In Xenopus, maternally supplied c-mos mRNA undergo...

journal_title：Bioscience trends

authors： Suzuki H,Tsukahara T,Inoue K

更新日期：2009-06-01 00:00:00

abstract：:Since the first outbreak of human infection with avian influenza A (H7N9) virus was identified in 2013, five seasonal outbreaks have occurred in China. The fifth outbreak started earlier than usual. A sudden increase in cases of human infection with avian influenza A (H7N9) virus has been reported in China since Septe...

journal_title：Bioscience trends

authors： Shen Y,Lu H

更新日期：2017-03-22 00:00:00

abstract：:We have recently demonstrated that unconjugated bilirubin (UCB) limits the overexpression of adhesion molecules and inhibits the PMN endothelial adhesion induced by the pro-inflammatory cytokine TNFalpha. To understand the molecular events involved we investigated whether the inhibitory effect is determined by a direc...

journal_title：Bioscience trends

authors： Mazzone GL,Rigato I,Ostrow JD,Tiribelli C

更新日期：2009-08-01 00:00:00

abstract：:Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been...

journal_title：Bioscience trends

authors： Lin J,Chen L,Qiu X,Zhang N,Guo Q,Wang Y,Wang M,Gober HJ,Li D,Wang L

更新日期：2017-07-24 00:00:00

abstract：:The aim of this study is to compare the efficacy of endoluminal ultrasonography (EUS) and spiral computerized tomography (SCT) in preoperative local staging of rectal carcinoma. EUS and SCT were performed prior to surgery in 78 patients with rectal carcinoma. After radical surgery, the preoperative findings were compa...

journal_title：Bioscience trends

authors： Ju H,Xu D,Li D,Chen G,Shao G

更新日期：2009-04-01 00:00:00

abstract：:The dominant-negative inhibition of KCNJ2-encoded inward rectifier potassium channels (Kir2) is currently considered the best approach to biological pacemakers. We hypothesized that inhibition of the inward rectifier potassium current (IK1) in ventricular myocytes by RNA interference (RNAi) would convert ventricular m...

journal_title：Bioscience trends

authors： Hu B,Zhu XL,Fan QX,Li HX,Zou CW

更新日期：2012-02-01 00:00:00

abstract：:As is similar to glial cell line-derived neurotrophic factor (GDNF), the Yangjing Capsule (YC) extract could also lead to proliferation of spermatogonial stem cells (SSCs) by stimulating the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway; however, the regulatory effect of YC extract on the expression ...

journal_title：Bioscience trends

authors： Jin B,Cai B,Sun D,Zhang X,Cui Y,Deng W,Gao C

更新日期：2017-03-22 00:00:00

abstract：:In Japan, a cost-containment policy has been implemented with health care system reform. Increasing medical expenses are inevitable due to aging of the population, health transitions, and expanded and advanced medical services. Policies such as the introduction of regressive reimbursement for inpatient services as par...

journal_title：Bioscience trends

authors： Idezuki Y

更新日期：2008-04-01 00:00:00

abstract：:Dengue is an acute febrile illness resulting from infection by a flavivirus transmitted by the Aedes mosquito. It is characterized by bleeding manifestations and a plasma leak syndrome. Hepatic involvement in the form of elevation in transaminases is common. However, acute hepatic failure is uncommon. It is not known ...

journal_title：Bioscience trends

authors： Agarwal MP,Giri S,Sharma V,Roy U,Gharsangi K

更新日期：2011-01-01 00:00:00

abstract：:We construct and validate a non-invasive clinical scoring model to predict mortality in HIV/TB patients at end stage of AIDS in China. There were 1,007 HIV/TB patients admitted to Beijing Ditan Hospital from August 2009 to January 2018 included in this study, who were randomly assigned to form derivation cohort and va...

journal_title：Bioscience trends

authors： Zhang Z,Xu L,Pang X,Zeng Y,Hao Y,Wang Y,Wu L,Gao G,Yang D,Zhao H,Xiao J

更新日期：2019-05-12 00:00:00

abstract：:Complete loss of function in the WRN: RecQ3 DNA/RNA helicase gene causes Werner Syndrome (WS). WS patients with genetic instability manifest an early onset of age-related diseases including diabetes mellitus (DM), osteoporosis, atherosclerosis, and malignancy as well as early death. In 1,420 patients, WS was reported ...

journal_title：Bioscience trends

authors： Goto M

更新日期：2008-08-01 00:00:00

abstract：:Laparoscopic liver resection (LLR) has garnered attention as a new form of liver surgery. In China, many hepatobiliary surgeons are now encouraging the examination and assessment of LLC in order to improve its outcomes, and several young hepatobiliary surgeons recently shared their clinical experiences and the results...

journal_title：Bioscience trends

authors： Zhao X,Song P,Zhang Y,Huang J

更新日期：2018-01-01 00:00:00

abstract：:MLS128 is an anti-carbohydrate monoclonal antibody (mAb) that binds three or two consecutive Tn-antigens. MLS128 bound 110-210 kDa glycoproteins (GPs) and inhibited the growth of LS180 and HT29 colon and MCF-7 breast cancer cells. One possible mechanism of MLS128's inhibition of growth may be via insulin-like growth f...

journal_title：Bioscience trends

authors： Zamri N,Masuda N,Oura F,Yajima Y,Nakada H,Fujita-Yamaguchi Y

更新日期：2012-12-01 00:00:00

abstract：:Citrus unshiu peel has been used to prevent and treat various diseases in traditional East-Asian medicine including in Korea. Extracts of C. unshiu peel are known to have various pharmacological effects including antioxidant, anti-inflammatory, and antibacterial properties. Although the possibility of their anti-cance...

journal_title：Bioscience trends

authors： Ahn KI,Choi EO,Kwon DH,HwangBo H,Kim MY,Kim HJ,Ji SY,Hong SH,Jeong JW,Park C,Kim ND,Kim WJ,Choi YH

更新日期：2017-11-20 00:00:00

abstract：:Obesity has become a severe public health problem worldwide. Crocin, a natural product, has been reported to have a number of pharmacological activities, including anti-inflammatory, anti-cancer, neuroprotective, antihypertensive, and cardioprotective action. The aims of the current study were to identify the benefici...

journal_title：Bioscience trends

authors： Gu M,Luo L,Fang K

更新日期：2018-01-01 00:00:00

abstract：:It has been hypothesized that subjective well-being (SWB) is determined by a combination of individual characteristics, social environment, and physical environment. However, few studies have simultaneously examined the relationships of the social and physical attributes of a neighborhood with SWB. Accordingly, the pr...

journal_title：Bioscience trends

authors： Gao J,Weaver SR,Fu H,Jia Y,Li J

更新日期：2017-11-20 00:00:00

abstract：:This meta-analysis aimed to review the regeneration rate of future liver remnant (FLR) and perioperative outcomes after associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) and two-stage hepatectomy (TSH). A web search was performed in "MEDLINE", "EMBASE", and "SCIENCE DIRECT" databases ...

journal_title：Bioscience trends

authors： Sun Z,Tang W,Sakamoto Y,Hasegawa K,Kokudo N

更新日期：2015-10-01 00:00:00

abstract：:On October 25, 2018, the National Health Commission of China issued the National Essential Medicines List (2018 edition) [NEML (2018)]. The NEML (2018) contains 685 drugs, which consist of 417 chemicals and biological products and 268 Chinese patent medicines. Compared to the 2012 version of the NEML, a total number o...

journal_title：Bioscience trends

authors： He J,Tang M,Ye Z,Jiang X,Chen D,Song P,Jin C

更新日期：2018-01-01 00:00:00

abstract：:Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Antibiotic resistance is rising to dangerously high levels in all parts of the world, leading to higher medical costs, prolonged hospital stays, and inc...

journal_title：Bioscience trends

authors： Tang Q,Song P,Li J,Kong F,Sun L,Xu L

更新日期：2016-02-01 00:00:00