Abstract:
:In oocytes, many maternally supplied products are stored, and these products play important roles in cell cycle regulation and early development. Mos protein, which is coded on the c-mos gene, promotes oocyte maturation and is involved in MAP-kinase signaling pathway. In Xenopus, maternally supplied c-mos mRNA undergoes poly(A) addition, and translational activation via CPE (cytoplasmic polyadenylation element) and CPEB (CPE binding protein). The elongated poly(A) is shortened and the c-mos mRNA is degraded during early embryogenesis via EDEN (embryo deadenylation element) and EDEN-BP (EDEN-binding protein). We cloned the full-length zebrafish c-mos gene, which is conserved at the protein coding region in vertebrates. c-mos mRNA has two putative CPE sequences in its 3'UTR, which binds to zebrafish CPEB homologous protein, Zor-1. We could not observe EDEN sequence, and could not detect interaction between c-mos mRNA and zebrafish EDEN-BP homologous protein, Brul, even though immuno precipitation and RT-PCR experiments suggested that c-mos mRNA interacts with Zor-1 in vivo. Interestingly, we found c-mos mRNA is located in the animal cortex of zebrafish oocyte, where Zor-1 protein exists. Taken together, these results suggest that the animal cortex is the central core of oocyte maturation in zebrafish.
journal_name
Biosci Trendsjournal_title
Bioscience trendsauthors
Suzuki H,Tsukahara T,Inoue Ksubject
Has Abstractpub_date
2009-06-01 00:00:00pages
96-104issue
3eissn
1881-7815issn
1881-7823journal_volume
3pub_type
杂志文章abstract::Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when bacteria change in response to the use of these medicines. Antibiotic resistance is rising to dangerously high levels in all parts of the world, leading to higher medical costs, prolonged hospital stays, and inc...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01034
更新日期:2016-02-01 00:00:00
abstract::In all malignant diseases, several clinical and histopathological tests are established as standard methods for diagnosis. Alternative diagnostic quantitative methods are still lacking or conflicting in cancer of the cervix. Although DNA analysis was one of the earliest applications in flow cytometry and the DNA conte...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2010-06-01 00:00:00
abstract::Aster yomena (Kitam.) Honda has been widely used as a traditional herbal medicine for centuries to treat cough, asthma, insect bites, etc. Recent reports indicate that A. yomena possesses a wide spectrum of pharmacological activities; however, few experiments have described its anti-inflammatory properties. The presen...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01217
更新日期:2017-03-22 00:00:00
abstract::The effects of anesthesia with sevoflurane and with propofol on glucose utilization in rats were investigated. Sevoflurane significantly impairs glucose utilization whereas propofol does not. Both insulin secretion and sensitivity affect glucose utilization. Propofol is hydrophobic, and anesthesia with this agent is a...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2014.01060
更新日期:2014-06-01 00:00:00
abstract::We retrospectively analyzed newborns with deafness gene mutations and summarized the relationship between genotype and phenotype to provide a basis for genetic counseling. We studied 582 subjects positive for deafness gene mutations that were treated in the otology outpatient department of Beijing Tongren Hospital, Ca...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01070
更新日期:2017-09-12 00:00:00
abstract::Laparoscopic liver resection (LLR) has garnered attention as a new form of liver surgery. In China, many hepatobiliary surgeons are now encouraging the examination and assessment of LLC in order to improve its outcomes, and several young hepatobiliary surgeons recently shared their clinical experiences and the results...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01086
更新日期:2018-01-01 00:00:00
abstract::The initial processes involved in radiation carcinogenesis have not been clearly elucidated. We isolated mouse mutant cells exhibiting plasticity in their mutation phenotypes. These mutant cells were originally isolated from an irradiated cell population as 6-thioguanine resistant (6TGR) mutants that were deficient in...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
abstract::Whether radioactive iodine treatment of Graves' disease (GD) during pregnancy will increase pregnancy loss and affect fetal development is still a matter of concern. From May 2005 to December 2015, 2,276 childbearing-age women with GD received iodine-131 treatment in our departments and were retrospectively enrolled i...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01008
更新日期:2016-09-05 00:00:00
abstract::In-stent restenosis is highly related to the deposition of inflammatory extracellular matrix and the migration of endothelial and vascular smooth muscle cells. The miR-17/TIMP-1/interleukin pathway regulates vascular matrix remodeling and plays an important role in the inflammatory reaction. This study identified miR-...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2019.01274
更新日期:2019-11-13 00:00:00
abstract::Adjuvant therapy after resection of hepatocellular carcinoma (HCC) is limited. Here, we evaluated the effects of postoperative sorafenib on recurrence and survival in HCC patients. Recurrence-free survival and overall survival were analyzed as the main endpoint, recurrence rate, and mortality rate were analyzed as sec...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2014.01120
更新日期:2014-12-01 00:00:00
abstract::Transplantation with Wharton's jelly derived mesenchymal stem cells (WJ-MSCs) showed great benefits for restoring myocardial function. However, the outcome of WJ-MSCs transplantation was unsuccessful due to multiple factors including oxidative damage. The presence of oxidative stress due to myocardium injury influence...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2019.01191
更新日期:2019-11-13 00:00:00
abstract::The current study retrospectively investigated variations in audiological phenotypes in children with GJB2 gene mutations. Subjects were 128 infants and young children who were seen as outpatients by Otology at Beijing Tongren Hospital from 2012 to 2018. Of the 128 subjects, 99 had biallelic truncating (T/T) mutations...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01159
更新日期:2018-09-19 00:00:00
abstract::Tissue engineering has been one of the most promising strategies for the regeneration of impaired tissue. Application of three-dimensional porous scaffolds has greatly improved the outcome of tissue engineering in many categories. Cell seeding is one of the key issues in tissue regeneration. It depends not only on the...
journal_title:Bioscience trends
pub_type: 杂志文章,评审
doi:
更新日期:2009-12-01 00:00:00
abstract::It has been hypothesized that subjective well-being (SWB) is determined by a combination of individual characteristics, social environment, and physical environment. However, few studies have simultaneously examined the relationships of the social and physical attributes of a neighborhood with SWB. Accordingly, the pr...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01170
更新日期:2017-11-20 00:00:00
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journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2012.v6.5.270
更新日期:2012-10-01 00:00:00
abstract::The aim of this study is to compare the efficacy of endoluminal ultrasonography (EUS) and spiral computerized tomography (SCT) in preoperative local staging of rectal carcinoma. EUS and SCT were performed prior to surgery in 78 patients with rectal carcinoma. After radical surgery, the preoperative findings were compa...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2009-04-01 00:00:00
abstract::At the end of 2013, a Japanese newspaper reported that 4,173 children were unidentified or missing in Japan. The article concluded that child abuse was a matter of national concern. In examining the strengths and weaknesses of Japan's welfare system in regard to child abuse, it would seem that a weakness exists with r...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract::The emerging novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has swept across the world and become a global threat to public health. More than 200 countries and territories worldwide are suffering from this COVID-19 pandemic. Worryingly, no specific vaccine...
journal_title:Bioscience trends
pub_type: 杂志文章,评审
doi:10.5582/bst.2020.03345
更新日期:2020-11-04 00:00:00
abstract::Precise diagnosis is a key measurement for malaria control and elimination, traditional microscopy and rapid diagnostic tests cannot satisfy the requirements especially in the low transmission endemic areas or in the malaria elimination phase. Polymerase chain reaction (PCR) with high sensitivity and specificity can b...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01198
更新日期:2018-01-01 00:00:00
abstract::Human papillomavirus (HPV) infections are common and generally harmless, but persistent infections can bring health problems like cancer and genital warts. For the uninfected group, HPV vaccines provide safe and effective protection, but they're type-restricted and expensive. For those infected, so far there have been...
journal_title:Bioscience trends
pub_type: 杂志文章,评审
doi:10.5582/bst.2017.01056
更新日期:2017-07-24 00:00:00
abstract::Obesity has become a severe public health problem worldwide. Crocin, a natural product, has been reported to have a number of pharmacological activities, including anti-inflammatory, anti-cancer, neuroprotective, antihypertensive, and cardioprotective action. The aims of the current study were to identify the benefici...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01240
更新日期:2018-01-01 00:00:00
abstract::Cardiomyocyte nutrient deprivation is a common clinical event that mediates various cardiac ischemic processes and is associated with autophagy activation and cell survival or death. Luteolin-7-O-glucoside (LUTG) was one of the flavonoid glycosides isolated from Dracocephalum tanguticum. Previous research had showed t...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01111
更新日期:2017-11-20 00:00:00
abstract::Postmenopausal osteoporosis (PMO) has become a public health problem worldwide. Hormonal replacement therapy (HRT) is the most popular treatment for PMO at present, but the side effects, including increased risk of endometrial cancer and breast cancer, limit its clinical use. Therefore, finding a new medication with h...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2019.01186
更新日期:2019-11-13 00:00:00
abstract::Dengue is an acute febrile illness resulting from infection by a flavivirus transmitted by the Aedes mosquito. It is characterized by bleeding manifestations and a plasma leak syndrome. Hepatic involvement in the form of elevation in transaminases is common. However, acute hepatic failure is uncommon. It is not known ...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2011.v5.1.44
更新日期:2011-01-01 00:00:00
abstract::Information about the muscarinic receptor subtype(s) mediating pulmonary circulatory vasodilator responses to acetylcholine (ACh) is limited. The aim of this study was to pharmacologically characterize the muscarinic receptors associated with ACh-induced pulmonary vasodilation in a pulmonary hypertension model. Vasodi...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:
更新日期:2010-10-01 00:00:00
abstract::Spontaneous esophageal perforation (Boerhaave's syndrome) is an uncommon and challenging condition with significant morbidity and mortality. Surgical treatment is indicated in the large majority of cases and different procedures have been described in this respect. We present the results of a mono-institutional evalua...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2016.01009
更新日期:2016-05-23 00:00:00
abstract::On October 25, 2018, the National Health Commission of China issued the National Essential Medicines List (2018 edition) [NEML (2018)]. The NEML (2018) contains 685 drugs, which consist of 417 chemicals and biological products and 268 Chinese patent medicines. Compared to the 2012 version of the NEML, a total number o...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2018.01265
更新日期:2018-01-01 00:00:00
abstract::The purpose of the present study was to evaluate whether pulse pressure variation (PPV) and stroke volume variation (SVV) can predict fluid responsiveness in patients with intra-abdominal hypertension (IAH) in either a supine or Trendelenburg position. Forty mechanically ventilated patients that exhibited IAH resultin...
journal_title:Bioscience trends
pub_type: 临床试验,杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract::Information about medical students' choice of specialty can be helpful for planning health manpower. However, such information from medical students in Malaysian medical schools is lacking. We carried out a cross-sectional questionnaire survey among fourth- and fifth-year medical undergraduate students at Melaka-Manip...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2011.v5.2.69
更新日期:2011-01-01 00:00:00
abstract::In patients at risk of hepatocarcinogenesis, tumors are frequently detected with atypical radiological patterns related to hepatocellular carcinoma (HCC) on imaging studies. Despite their high potential for malignancy, whether to resect such lesions immediately is controversial. Based on histological findings, patient...
journal_title:Bioscience trends
pub_type: 杂志文章
doi:10.5582/bst.2017.01110
更新日期:2017-07-24 00:00:00