Inbreeding and purging at the genomic Level: the Chillingham cattle reveal extensive, non-random SNP heterozygosity.

abstract：:Rumplessness in Hongshan chickens has been reported as a novel sex-linked characteristic. Re-sequencing data suggest that a pseudogene on the Z chromosome, LOC431648, is affiliated with this phenotype. In this study, we chose 23 rumpless and 25 normal Hongshan chickens to localize the potential variation by means of a...

journal_title：Animal genetics

authors： Wang Q,Pi J,Shen J,Pan A,Qu L

更新日期：2018-08-01 00:00:00

abstract：:Cytochrome P450-aromatase enzyme (CYP19), which catalyses the conversion of androgens to oestrogens, is critical in ovarian differentiation and hence in the sex differentiation pathways of non-mammalian vertebrates. As in other fish species, distinct ovarian and brain aromatase genes have been identified in the Nile T...

journal_title：Animal genetics

authors： Harvey SC,Kwon JY,Penman DJ

更新日期：2003-02-01 00:00:00

abstract：:Comparative anchor tagged sequence (CATS) consensus primers from loci mapped to human chromosomes 9, 10, 20, and 22 have been used to amplify homologous loci in pigs. Of 53, CATS primers tested in pigs, only 23 yielded products homologous to the human locus (42% success). Ten loci were physically mapped (43% success r...

journal_title：Animal genetics

authors： Lee JH,Zhang W,Moran C

更新日期：2001-10-01 00:00:00

abstract：:Specific alloprecipitins were found in blood plasma of pigs, immunized by sera of Lpr1 positive donors. These precipitins detected a new allotype of the lipoprotein Lpr system which was designated Lpr3. Genetic studies confirmed its codominant inheritance and subgroup character. This linear subgroup of allotype Lpr1 i...

journal_title：Animal genetics

authors： Hojný J,Janik A,Schröffel J Jr

更新日期：1993-12-01 00:00:00

abstract：:A specific white spotting phenotype, termed finching or line-backed spotting, is known for all Pinzgauer cattle and occurs occasionally in Tux-Zillertaler cattle, two Austrian breeds. The so-called Pinzgauer spotting is inherited as an autosomal incompletely dominant trait. A genome-wide association study using 27 whi...

journal_title：Animal genetics

authors： Küttel L,Letko A,Häfliger IM,Signer-Hasler H,Joller S,Hirsbrunner G,Mészáros G,Sölkner J,Flury C,Leeb T,Drögemüller C

更新日期：2019-10-01 00:00:00

abstract：:Genetic differences which exist in the prion protein gene (PRNP) have been reported to influence susceptibility of humans, sheep and goats to prion diseases. In cattle, however, none of the known coding polymorphisms has a direct effect on bovine spongiform encephalopathy (BSE). It has been reported that 23-bp inserti...

journal_title：Animal genetics

authors： Msalya G,Shimogiri T,Nishitani K,Okamoto S,Kawabe K,Minesawa M,Maeda Y

更新日期：2010-04-01 00:00:00

abstract：:The European sea bass (Dicentrarchus labrax L.) is a marine fish of key economic and cultural importance in Europe. It is now more an aquaculture than a fisheries species (>96% of the production in 2016), although modern rearing techniques date back only from the late 1980s. It also has high interest for evolutionary ...

journal_title：Animal genetics

authors： Vandeputte M,Gagnaire PA,Allal F

更新日期：2019-06-01 00:00:00

abstract：:We present the first radiation hybrid (RH) map of river buffalo (Bubalus bubalis) chromosome 6 (BBU6) developed with a recently constructed river buffalo whole-genome RH panel (BBURH(5000)). The preliminary map contains 33 cattle-derived markers, including 12 microsatellites, 19 coding genes and two ESTs, distributed ...

journal_title：Animal genetics

authors： Stafuzza NB,Ianella P,Miziara MN,Agarwala R,Schäffer AA,Riggs PK,Womack JE,Amaral ME

更新日期：2007-08-01 00:00:00

abstract：:MicroRNA (miRNA) is a class of single-stranded small (19-24nt) regulatory RNA that silences gene expression post-transcriptionally. miRNAs regulate a wide range of biological processes through the recognition of complementary sequences between miRNAs and their target genes. Profiling studies in livestock have revealed...

journal_title：Animal genetics

authors： Liu HC,Hicks JA,Trakooljul N,Zhao SH

更新日期：2010-06-01 00:00:00

abstract：:Previously, we re-sequenced the whole genomes of eight Holstein bulls with high or low milk protein and fat percentage, and we detected two indels in the ACACB (acetyl-CoA carboxylase beta) gene that were polymorphic between the two groups. Thus, we considered ACACB as a promising candidate gene potentially affecting ...

journal_title：Animal genetics

authors： Han B,Liang W,Liu L,Li Y,Sun D

更新日期：2018-06-01 00:00:00

abstract：:Summary Long-chain acyl-CoA synthetase (ACSL) catalyses the formation of long-chain acyl-CoA from fatty acid, ATP and CoA, activating fatty acids for subsequent reactions. Long-chain acyl-CoA synthetase thus plays an essential role in both lipid biosynthesis and fatty acid degradation. The ACSL4 gene was evaluated as ...

journal_title：Animal genetics

authors： Mercadé A,Estellé J,Pérez-Enciso M,Varona L,Silió L,Noguera JL,Sánchez A,Folch JM

更新日期：2006-06-01 00:00:00

abstract：:Embryonic survival rate, an important factor in the fecundity of sows, is affected by endometrium-secreting histotroph. A higher concentration of calcium ion has been observed in the uterus of highly prolific Erhualian sows (EH) compared with those of less prolific (EL) sows. This suggests that EH sows have better est...

journal_title：Animal genetics

authors： Ma X,Li P,Zhang Q,He L,Su G,Huang Y,Lu Z,Hu W,Ding H,Huang R

更新日期：2019-08-01 00:00:00

abstract：:In this study, we have characterized the mitochondrial diversity of 81 swine from Uganda. Median-joining network analysis of D-loop sequences from these individuals and others characterized in previous studies allowed us to determine that Ugandan pigs cluster with populations from the West (Europe/North Africa), Far E...

journal_title：Animal genetics

authors： Noce A,Amills M,Manunza A,Muwanika V,Muhangi D,Aliro T,Mayega J,Ademun R,Sànchez A,Egbhalsaied S,Mercadé A,Masembe C

更新日期：2015-08-01 00:00:00

abstract：:The objectives of this study were to assign both microsatellite and gene-based markers on porcine chromosome X to two radiation hybrid (RH) panels and to develop a more extensive integrated map of SSC-X. Thirty-five microsatellite and 20 gene-based markers were assigned to T43RH, and 16 previously unreported microsate...

journal_title：Animal genetics

authors： McCoard SA,Fahrenkrug SC,Alexander LJ,Freking BA,Rohrer GA,Wise TH,Ford JJ

更新日期：2002-06-01 00:00:00

abstract：:A putative functional mutation (rs109231213) near PLAG1 (BTA14) associated with stature was studied in beef cattle. Data from 8199 Bos taurus, Bos indicus and Tropical Composite cattle were used to test the associations between rs109231213 and various phenotypes. Further, 23 496 SNPs located on BTA14 were tested for a...

journal_title：Animal genetics

authors： Fortes MR,Kemper K,Sasazaki S,Reverter A,Pryce JE,Barendse W,Bunch R,McCulloch R,Harrison B,Bolormaa S,Zhang YD,Hawken RJ,Goddard ME,Lehnert SA

更新日期：2013-12-01 00:00:00

abstract：:A quantitative trait locus (QTL) for boar fat androstenone levels has been identified near the SSC7 centromere in a Large White × Meishan cross. Backcrosses were produced to isolate the Chinese haplotype in a European genetic background. The expression of 25 genes from the QTL region was studied in the testes and live...

journal_title：Animal genetics

authors： Robic A,Fève K,Larzul C,Billon Y,van Son M,Liaubet L,Sarry J,Milan D,Grindflek E,Bidanel JP,Riquet J

更新日期：2011-12-01 00:00:00

abstract：:In this study, we performed a sequence characterization of the duck melanocortin 1 receptor (alpha-melanocyte stimulating hormone receptor) (MC1R) gene to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extended black (E) and non-extended black (e(+) ) a...

journal_title：Animal genetics

authors： Yu W,Wang C,Xin Q,Li S,Feng Y,Peng X,Gong Y

更新日期：2013-04-01 00:00:00

abstract：:Africa is host to diverse and locally adapted cattle breeds that are expected to survive the harsh and extreme tropical environments associated with diseases and parasite infections, heat stress and episodes of feed and water scarcity. Genomic copy number variations (CNVs) are considered to be primary role players in ...

journal_title：Animal genetics

authors： Wang MD,Dzama K,Rees DJ,Muchadeyi FC

更新日期：2016-04-01 00:00:00

abstract：:A synthetic oligodeoxyribonucleotide probe (OAT36) comprising nine repeats of 5'GACA 3' and several enzymes were used to analyse cow, (Bos taurus) and buffalo (Bubalus bubalis) genomes and a number of monomorphic loci were detected in both the species. Different animals from the same species showed an almost 'similar'...

journal_title：Animal genetics

authors： Ali S,Gauri,Bala S

更新日期：1993-06-01 00:00:00

abstract：:Recurrent airway obstruction (RAO) in horses is the result of an interaction of genetic and environmental factors and shares many characteristics with human asthma. Many studies have suggested that the interleukin-4 receptor gene (IL4R) is associated with this disease, and a QTL region on chromosome 13 containing IL4R...

journal_title：Animal genetics

authors： Klukowska-Rötzler J,Swinburne JE,Drögemüller C,Dolf G,Janda J,Leeb T,Gerber V

更新日期：2012-08-01 00:00:00

abstract：:The myxovirus resistance (Mx) proteins belong to the dynamin superfamily and are important for innate host defence against RNA viruses. In this study, we demonstrate that positive elements are present in the two promoter regions of -2713 to -2565 and -688 to -431 in the porcine MX1 gene. Sequencing and alignment of th...

journal_title：Animal genetics

authors： Li Y,Liang S,Liu H,Sun Y,Kang L,Jiang Y

更新日期：2015-08-01 00:00:00

abstract：:We have for the first time assessed the ability of the Sleeping Beauty (SB) transposon system to enhance transgenesis in chicken and turkey cells. The efficiency of transgenesis with a transposon encoding an antibiotic resistance gene was dramatically enhanced 15- to 35-fold when transposase was supplied by co-transfe...

journal_title：Animal genetics

authors： Kong BW,Carlson DF,Fahrenkrug SC,Foster DN

更新日期：2008-04-01 00:00:00

abstract：:The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was t...

journal_title：Animal genetics

authors： Jäderkvist Fegraeus K,Hirschberg I,Árnason T,Andersson L,Velie BD,Andersson LS,Lindgren G

更新日期：2017-12-01 00:00:00

abstract：:The genetic consequences of population differentiation and isolation have been the subject of conservation biology. In this study, we analysed the genetic diversity and structure of Mongolian sheep in China. These animals belong to a traditional local breed with high production, extensive adaption, early maturity and ...

journal_title：Animal genetics

authors： Zhong T,Han JL,Guo J,Zhao QJ,Fu BL,Pu YB,He XH,Jeon JT,Guan WJ,Ma YH

更新日期：2011-10-01 00:00:00

abstract：:Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B-G restriction fragment length polymorphism (RFLP) analysis, allele-specific PCR typing test for B-LBII family...

journal_title：Animal genetics

authors： Livant EJ,Zheng D,Johnson LW,Shi W,Ewald SJ

更新日期：2001-06-01 00:00:00

abstract：:Tibial dyschondroplasia (TD) is a genetic leg defect in broilers with a lesion of avascular, non-calcified cartilage below the growth plate of the proximal tibiatarsus. This disease is considered to result from the inability of chondrocytes to undergo terminal differentiation. Thyroid hormones are required for chondro...

journal_title：Animal genetics

authors： Shen S,Berry W,Jaques S,Pillai S,Zhu J

更新日期：2004-04-01 00:00:00

abstract：:Genomic imprinting is a mammalian developmental process that uses epigenetic mechanisms to induce monoallelic and parental-specific expression of particular autosomal genes. A crucial epigenetic event consists of DNA methylation of CpG-islands, which become differentially methylated regions (DMRs) on the maternal and ...

journal_title：Animal genetics

authors： Colosimo A,Di Rocco G,Curini V,Russo V,Capacchietti G,Berardinelli P,Mattioli M,Barboni B

更新日期：2009-12-01 00:00:00

abstract：:DNA samples obtained from sheep homozygous for HbA, for HbB and heterozygous were subjected to Southern blot analysis using a goat beta F and a rabbit beta 1-globin gene as probes. Sheep homozygous for HbA show a different restriction pattern from that of sheep homozygous for HbB with each of the used endonucleases. T...

journal_title：Animal genetics

authors： Di Gregorio P,Rando A,Masina P

更新日期：1987-01-01 00:00:00

abstract：:Overlapping runs of homozygosity (ROH islands) shared by the majority of a population are hypothesized to be the result of selection around a target locus. In this study we investigated the impact of selection for coat color within the Noriker horse on autozygosity and ROH patterns. We analyzed overlapping homozygous ...

journal_title：Animal genetics

authors： Grilz-Seger G,Druml T,Neuditschko M,Mesarič M,Cotman M,Brem G

更新日期：2019-08-01 00:00:00

abstract：:The crest in chicken consists of elongated and upraised feathers, as seen in various breeds such as the Silkie chicken. Recently, the still unknown causative mutation for the crest phenotype was assigned to chromosome 33 and an ectopic expression of HOXC8 was shown. The aim this study was to evaluate whether the crest...

journal_title：Animal genetics

authors： Joller S,Ammann P,Flury C,Drögemüller C

更新日期：2018-08-01 00:00:00