Models of gastroenteropancreatic neuroendocrine neoplasms - Current status and future directions.

abstract：:The properties of neuronal-type nicotinic acetylcholine receptors (nAChRs) present on the neuroendocrine cells of the porcine pars intermedia of the pituitary were studied in intact single cell using measurements of the free intracellular Ca2+ concentration ([Ca]i) with the calcium-sensitive dye fura 2. Local applicat...

journal_title：Neuroendocrinology

authors： Poisbeau P,Trouslard J,Feltz P,Schlichter R

更新日期：1994-10-01 00:00:00

abstract：:The differential role of porcine follicular fluid (pFF) in regulating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release in vivo in situations of different gonadotropin releasing hormone (GnRH) backgrounds was studied. In experiment 1, 2-week ovariectomized rats injected intravenously with 4, 16 o...

journal_title：Neuroendocrinology

authors： Charlesworth MC,Grady RR,Shin L,Vale WW,Rivier C,Rivier J,Schwartz NB

更新日期：1984-03-01 00:00:00

abstract：:A patch-clamp study was conducted on cultured frog pituitary melanotrophs, in order to investigate the effects of adrenaline on the electrical activity of these cells. In the whole-cell configuration, adrenaline (1 microM) caused hyperpolarization that was accompanied by a fall in membrane input resistance and a block...

journal_title：Neuroendocrinology

authors： Valentijn JA,Vaudry H,Cazin L

更新日期：1994-01-01 00:00:00

abstract：:Single rat neurohypophyses were impaled on a platinum electrode, perifused with isotonic medium and fractions of perifusate collected each minute. Arginine vasopressin content of the fractions was measured by radioimmunoassay. The basal release of arginine vasopressin varied from 50 to 350 pg (0.02-0.14 mU/min) betwee...

journal_title：Neuroendocrinology

authors： Bicknell RJ,Leng G

更新日期：1981-11-01 00:00:00

abstract：:We have investigated the effects of exposure to short-term constant light (LL) on the spontaneous, proestrous luteinizing hormone (LH) surge in the female rat. Exposure to LL during the 3 days preceding proestrus delayed and reduced the magnitude of the LH surge which was measured in blood samples taken from conscious...

journal_title：Neuroendocrinology

authors： Watts AG,Fink G

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Neuroendocrine tumors (NETs) are rare and characterized by a heterogeneous clinical course and an unmet need for better prognostic markers. Plasma cell-free DNA (cfDNA) has prognostic value in other malignancies but is not previously investigated in NETs. We studied cfDNA levels in patients with mainly low g...

journal_title：Neuroendocrinology

authors： Oversoe SK,Sorensen BS,Tabaksblat EM,Gronbaek H,Kelsen J

更新日期：2021-01-18 00:00:00

abstract：:A consistent group of gonadotropin-releasing hormone (GnRH) cell bodies occurs in the ventral hypothalamic tract at the infundibular lip (IL), just below the arcuate nucleus (ARC), at the site of the so-called GnRH 'pulse generator'. Immunocytochemical studies were performed to examine contacts between these GnRH neur...

journal_title：Neuroendocrinology

authors： Thind KK,Goldsmith PC

更新日期：1988-03-01 00:00:00

abstract：:Knowledge of specific neurotransmitters as well as the pathways and mechanisms regulating appetite in ruminants that continually graze, such as sheep, is incomplete. Although fundamentally agouti-related protein (AGRP) has a similar function across species to increase food intake, the regulation of AGRP may vary acros...

journal_title：Neuroendocrinology

authors： Wagner CG,McMahon CD,Marks DL,Daniel JA,Steele B,Sartin JL

更新日期：2004-01-01 00:00:00

abstract：:The effects of acute stress exposure upon cholecystokinin (CCK) and substance P (SP) concentrations in discrete hypothalamic regions of the adult male rat brain were studied. Animals were exposed to foot shock stress for periods of 2, 4, 10, 30 or 60 min duration; immediately afterwards they were decapitated; brains w...

journal_title：Neuroendocrinology

authors： Siegel RA,Düker EM,Pahnke U,Wuttke W

更新日期：1987-06-01 00:00:00

abstract：:Using specific antibodies to corticotrophin-releasing factor (CRF) and arginine vasopressin (AVP) we have immunocytochemically located cells and fibres containing these peptides in sheep fetuses. CRF neurones were first detected, in low frequency, in the paraventricular nuclei of fetuses of 90 days of gestation (term ...

journal_title：Neuroendocrinology

authors： Levidiotis M,Oldfield B,Wintour EM

更新日期：1987-11-01 00:00:00

abstract：:The mechanisms involved in the activation of the hypothalamus-pituitary-adrenal axis after administration of Mycoplasma fermentans were examined. Male rats were injected intracerebroventricularly (i.c.v.) with heat-inactivated M. fermentas (6 micrograms protein/10 microliters/rat) or vehicle and were killed 2 h later....

journal_title：Neuroendocrinology

authors： Wohlman A,Gallily R,Yirmiya R,Weidenfeld J

更新日期：1997-09-01 00:00:00

abstract：:Incubation of cultured goldfish pituitary cells with 10 nM to 1 microM apomorphine (APO), a non-selective dopamine agonist, increased growth hormone (GH) release in a dose-dependent manner. GH release was also stimulated in a dose-dependent manner by 0.1 nM to 1 microM salmon gonadotropin (GTH)-releasing hormone (sGnR...

journal_title：Neuroendocrinology

authors： Chang JP,Yu KL,Wong AO,Peter RE

更新日期：1990-06-01 00:00:00

abstract：INTRODUCTION:Small-intestinal neuroendocrine tumors (SI-NET) are situated preferentially within the ileum. The aim was to describe a potential difference in location between unifocal and multiple ileal-NET. METHODS:Between December 2010 and December 2019, all consecutive patients who underwent resection in our Europea...

journal_title：Neuroendocrinology

authors： Kalifi M,Walter T,Milot L,Hervieu V,Millot I,Gibert B,Roche C,Forestier J,Lombard-Bohas C,Pasquer A,Poncet G

更新日期：2020-09-30 00:00:00

abstract：:In rats anesthetized with sodium pentobarbital, adrenal venous blood samples were collected and analyzed for epinephrine and norepinephrine by the fluorometric method. Stimulation of the inferior fovea or adjacent areas resulted in a significant increase in epinephrine secretion. Stimulation of some other areas of the...

journal_title：Neuroendocrinology

authors： Matsui H

更新日期：1979-01-01 00:00:00

abstract：:Intracranial implants of estradiol benzoate (EB) were used to explore sites of action for the activation of masculine copulatory behavior in castrated male rats. In experiment 1, 27 or 30 gauge implants were placed unilaterally throughout the hypothalamus and preoptic area. Dihydrotestosterone (DHT) was administered s...

journal_title：Neuroendocrinology

authors： Davis PG,Barfield RJ

更新日期：1979-01-01 00:00:00

abstract：:Visual average evoked responses (AERs) to 4 intensities of light were studied in 5 patients with adrenal cortical insufficiency. Patients were tested off all medications, on ACTH while off all medications, and during replacement with carbohydrate-active steroids. Off treatment, when steroid levels were low, AERs were ...

journal_title：Neuroendocrinology

authors： Buchsbaum MS,Henkin RI

更新日期：1975-01-01 00:00:00

abstract：:In pituitary cells, c-fos transcription induced by releasing hormones and growth factors results from enhanced initiation of transcription, and sustained elongation of transcripts beyond the first intron. We studied the regulatory role of the first intron of the mouse c-fos gene for the control of its transcription in...

journal_title：Neuroendocrinology

authors： van Haasteren G,Li S,Ryser S,Schlegel W

更新日期：2000-12-01 00:00:00

abstract：:Adenylate cyclase activity was studied in anterior pituitary homogenates from young adult (6 months) and old (20 and 24 months) male rats. Basal, NaF-, GTP-, 5'-guanylimidodiphosphate (Gpp(NH)p)- and forskolin-stimulated activities were similar in the three groups, implying that the stimulatory guanyl nucleotide regul...

journal_title：Neuroendocrinology

authors： Robberecht P,Gillard M,Waelbroeck M,Camus JC,De Neef P,Christophe J

更新日期：1986-01-01 00:00:00

abstract：:alpha-Methyl-p-tyrosine (alpha-MT), a competitive inhibitor of tyrosine hydroxylase, was used to block the synthesis of hypothalamic catecholamines in immature female rats of 14, 16 and 30 days of age and in castrated adults. The administration of alpha-MT (300 mg/kg body weight, free base) induced a significant decay...

journal_title：Neuroendocrinology

authors： Moguilevsky JA,Arias P,Szwarcfarb B,Carbone S,Rondina D

更新日期：1990-10-01 00:00:00

abstract：:Ghrelin is a 28-amino-acid gastric peptide that potently stimulates growth hormone (GH) secretion in vivo and in vitro. Ghrelin-expressing cells have been found in the oxyntic region of the stomach and in the arcuate nucleus of the hypothalamus. The aim of this work was to investigate the regional distribution and dev...

journal_title：Neuroendocrinology

authors： Torsello A,Scibona B,Leo G,Bresciani E,Avallone R,Bulgarelli I,Luoni M,Zoli M,Rindi G,Cocchi D,Locatelli V

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND/AIMS:The medial amygdala (MeA) responds to olfactory stimuli and alters reproductive physiology. However, the neuronal circuit that relays signals from the MeA to the reproductive axis remains poorly defined. This study aimed to test whether MeA kisspeptin (MeAKiss) neurons in male mice are sensitive to sexu...

journal_title：Neuroendocrinology

authors： Aggarwal S,Tang C,Sing K,Kim HW,Millar RP,Tello JA

更新日期：2019-01-01 00:00:00

abstract：:Previous studies have shown that prepubertal olfactory bulbectomy will prevent the testicular regression associated with short photoperiod in golden hamsters. The gonadal regression which normally occurs in hamsters on short photoperiod is known to be due in part to an increased responsiveness of the reproductive neur...

journal_title：Neuroendocrinology

authors： Pieper DR,Unthank PD,Shuttie DA,Lobocki CA,Swann JM,Newman S,Subramanian MG

更新日期：1987-10-01 00:00:00

abstract：:The effect of aging on the release of gonadotropin-releasing hormone (GnRH) in vitro and of luteinizing hormone (LH) both in vivo and in vitro in ovariectomized (Ovx) rats was studied. Old (21-24 months) and young (3-4 months) rats were Ovx before use. They were injected subcutaneously with estradiol benzoate (25 micr...

journal_title：Neuroendocrinology

authors： Hwang C,Pu HF,Hwang CY,Liu JY,Yao HC,Tung YF,Wang PS

更新日期：1990-08-01 00:00:00

abstract：:Hypothalamic norepinephrine (NE) and dopamine content was studied in dogs with spontaneous and iatrogenic hypercortisolism and in untreated normal dogs. The concentration of NE in the hypothalamus was subnormal in 4 of 8 dogs with pituitary-dependent hyperadrenocorticism (PDH), whereas long-term administration of cort...

journal_title：Neuroendocrinology

authors： Meijer JC,Croughs RJ,Rijnberk A,Versteeg DH,van Ree JM

更新日期：1981-04-01 00:00:00

abstract：:Specific lesions of different brain structures known to contain or to be coursed by LHRH neurons have been carried out in intact cycling female rats in order to investigate the role played by central LHRH and neuronal systems in the regulation of ovarian and hypophyseal LHRH receptor (LHRH-R) levels, using the stable ...

journal_title：Neuroendocrinology

authors： Marchetti B,Cioni M,Scapagnini U

更新日期：1985-10-01 00:00:00

abstract：:Somatostatin receptors on lactotroph cells of the anterior pituitary are positively regulated by estradiol. In the present work, we investigated whether estradiol regulation of somatostatin receptors also occurred in the female rat brain. 125I-Tyr0-DTrp8-somatostatin (125I-SRIF: 780 Ci/mM) was used as a ligand. Female...

journal_title：Neuroendocrinology

authors： Slama A,Videau C,Kordon C,Epelbaum J

更新日期：1992-08-01 00:00:00

abstract：:Dehydration is a classic homeostatic stressor in rats that leads to a series of endocrine responses including stimulation of the hypothalamo-pituitary-adrenal (HPA) axis. During the last decade, it has been well established that perinatal food restriction is associated with the onset of diseases in adults. Our previou...

journal_title：Neuroendocrinology

authors： Sebaai N,Lesage J,Breton C,Vieau D,Deloof S

更新日期：2004-01-01 00:00:00

abstract：:Structural and functional impairment of the skeletal system remains an important cause of morbidity and disability in patients with Cushing's syndrome (CS). Glucocorticoid (GC) excess inhibits bone formation and calcium absorption from the gut, increases bone resorption, and alters the secretion of gonadotropin and gr...

journal_title：Neuroendocrinology

authors： Kaltsas G,Makras P

更新日期：2010-01-01 00:00:00

abstract：:The relationship between the growth hormone/insulin-like growth factor (GH-IGF)-I status and memory performance is studied in 24 elderly males and females, aged 75-85 years. Positron emission tomography (PET) was used to measure differences in regional cerebral blood flow during the performance of a delayed-non-match-...

journal_title：Neuroendocrinology

authors： Arwert LI,Veltman DJ,Deijen JB,Lammertsma AA,Jonker C,Drent ML

更新日期：2005-01-01 00:00:00

abstract：:Neurons in the adult rat ventromedial hypothalamic nucleus (VMN, 4-6 neurons per brain; 3-7 brains per group) were studied under various hormonal conditions using the single-section Golgi impregnation technique. Intact rats of both sexes and ovariectomized females treated with oil, estrogen or estrogen and progesteron...

journal_title：Neuroendocrinology

authors： Frankfurt M,Gould E,Woolley CS,McEwen BS

更新日期：1990-05-01 00:00:00