Hypothalamic catecholamine levels in dogs with spontaneous hyperadrenocorticism.

abstract：:The reuptake of dopamine into nerve terminals is the primary mechanism of inactivation of this neurotransmitter in the synaptic cleft. We report sex differences and estrous cycle variations of rat striatal dopamine uptake sites. During the estrous cycle, peak density of striatal dopamine uptake sites labelled with [3H...

journal_title：Neuroendocrinology

authors： Morissette M,Di Paolo T

更新日期：1993-07-01 00:00:00

abstract：:Corticosteroids regulate gene expression through the activation of mineralocorticoid and glucocorticoid receptors. The hippocampus contains the highest density of mineralocorticoid and glucocorticoid receptors in the central nervous system. The modulation of neuron excitability by corticosteroids in hippocampal subfie...

journal_title：Neuroendocrinology

authors： Okuhara DY,Beck SG

更新日期：1998-01-01 00:00:00

abstract：:The influence of catecholamines (CA) on hypothalamic somatostatin (HPT-SRIF) was investigated in rats by using several drugs which interfere with brain CA metabolism. Depletion of brain CA stores by alpha-methyl-rho-tyrosine (AMT) increased HPT-SRIF, while augmented brain CA levels following L-dopa administration decr...

journal_title：Neuroendocrinology

authors： Torres I,Guaza C,Fernandez-Durango R,Borrell J,Charro AL

更新日期：1982-01-01 00:00:00

abstract：:In all vertebrates, the regulations of growth and energy balance are complex phenomena which involve elaborate interactions between the brain and peripheral signals. Most vertebrates adopt and maintain a life style after birth, but lower vertebrates may have complex life histories involving metamorphoses, migrations a...

journal_title：Neuroendocrinology

authors： Rousseau K,Dufour S

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:The pituitary gland has a high expression of somatostatin receptors (SSTRs) and is therefore a potential organ at risk for radiation-induced toxicity after 177Lu-DOTATATE treatment. OBJECTIVE:To study changes in pituitary function in patients with neuroendocrine tumors (NETs) treated with dosimetry-based ...

journal_title：Neuroendocrinology

authors： Sundlöv A,Sjögreen-Gleisner K,Tennvall J,Dahl L,Svensson J,Åkesson A,Bernhardt P,Lindgren O

更新日期：2020-04-08 00:00:00

abstract：:Studies were conducted to determine if the hypothermic effects of barbiturates were responsible for their ability to suppress luteinizing hormone (LH) secretion in rats following ovariectomy or treatment with gonadal steroids. In both ovariectomized rats and rats treated with estradiol and progesterone, pentobarbital ...

journal_title：Neuroendocrinology

authors： Simpkins JW,Katovich MJ

更新日期：1987-09-01 00:00:00

abstract：:The differential role of porcine follicular fluid (pFF) in regulating follicle-stimulating hormone (FSH) and luteinizing hormone (LH) release in vivo in situations of different gonadotropin releasing hormone (GnRH) backgrounds was studied. In experiment 1, 2-week ovariectomized rats injected intravenously with 4, 16 o...

journal_title：Neuroendocrinology

authors： Charlesworth MC,Grady RR,Shin L,Vale WW,Rivier C,Rivier J,Schwartz NB

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND/AIMS:Stress exacerbates neuron loss in many CNS injuries via the actions of adrenal glucocorticoid (GC) hormones. For some injuries, this GC endangerment of neurons is accompanied by greater immune cell activation in the CNS, a surprising outcome given the potent immunosuppressive properties of GCs. METHODS...

journal_title：Neuroendocrinology

authors： Sorrells SF,Munhoz CD,Manley NC,Yen S,Sapolsky RM

更新日期：2014-01-01 00:00:00

abstract：:Intestinal gluconeogenesis is a recently described function in intestinal glucose metabolism. In particular, the intestine contributes around 20-25% of total endogenous glucose production during fasting. Intestinal gluconeogenesis appears to regulate energy homeostasis via a neurally mediated mechanism linking the ent...

journal_title：Neuroendocrinology

authors： Mithieux G

更新日期：2014-01-01 00:00:00

abstract：:The ability of the flutamide metabolite Sch 16423 to block androgen receptor binding and inhibit masculine copulatory behavior in male rats was examined. Restoration of copulatory behavior was prevented in Sch 16423-treated rats given two 10-mm testosterone (T)-filled Silastic capsules plus 15 mg Sch 16423 daily for 1...

journal_title：Neuroendocrinology

authors： McGinnis MY,Mirth MC

更新日期：1986-01-01 00:00:00

abstract：:It is known that the neonatal treatment of rats with monosodium L-glutamate (MSG) induces several metabolic abnormalities, resulting in enhanced adiposity and hyperleptinemia. Our study was designed to explore the consequences of MSG-induced chronic hyperleptinemia on adrenal sensitivity to the inhibitory effect of ex...

journal_title：Neuroendocrinology

authors： Perelló M,Gaillard RC,Chisari A,Spinedi E

更新日期：2003-09-01 00:00:00

abstract：:Gastric carcinoids are rare neuroendocrine tumors, usually classified as type I, if associated with atrophic body gastritis; type II, if associated with Zollinger-Ellison syndrome and multiple endocrine neoplasia type I, and type III, in the absence of any gastric pathology (sporadic tumors). The pathological features...

journal_title：Neuroendocrinology

authors： Delle Fave G,Capurso G,Annibale B,Panzuto F

更新日期：2004-01-01 00:00:00

abstract：:Using two tests in intact adult rats, it has been found that a high positive correlation exists (p less than 0.005) between the ovulation inhibiting and the serotonin antagonistic activities measured in vivo of five tricyclic compounds and ten ergot derivatives. In these chemically different classes of compounds, cert...

journal_title：Neuroendocrinology

authors： Markó M,Flückiger E

更新日期：1980-04-01 00:00:00

abstract：:Adrenocorticotropic hormone (ACTH) is the major regulator of adrenocortical steroidogenesis in mammals. By comparing the sensitivity to ACTH of isolated adrenocortical cells from two sources of the same strain (Sprague-Dawley, SD) of outbred rats, we have identified a source of rat with low sensitivity to ACTH in vitr...

journal_title：Neuroendocrinology

authors： Matthys L,Castello R,Zilz A,Widmaier EP

更新日期：1998-06-01 00:00:00

abstract：:An influence of thyroid status on the secretory activity of hypothalamic dopaminergic neurons was observed in adult rats and its involvement in the regulation of prolactin (PRL) secretion was examined. The secretory activity of the tuberoinfundibular dopaminergic (TIDA) neurons was evaluated by measurement of dopamine...

journal_title：Neuroendocrinology

authors： Reymond MJ,Benotto W,Lemarchand-Béraud T

更新日期：1987-06-01 00:00:00

abstract：:Prolactin (PRL) secretion in the female rat is regulated by an endogenous stimulatory rhythm (ESR), which is normally under the tonic inhibition of dopamine (DA). The ESR consists of a nocturnal (N) component which peaks at approximately 03.00 h, and a diurnal (D) component which peaks at approximately 17.00 h. This E...

journal_title：Neuroendocrinology

authors： Arey BJ,Kanyicska B,Freeman ME

更新日期：1991-01-01 00:00:00

abstract：:Brain angiotensin II (AII) receptors play a role in the regulation of luteinizing hormone release. This action is thought to involve luteinizing hormone-releasing hormone containing neurons in the preoptic-anterior hypothalamic (POAH) area of the brain. Previous studies have demonstrated a discrete locus of AII recept...

journal_title：Neuroendocrinology

authors： Grove KL,Cook VI,Speth RC

更新日期：1992-08-01 00:00:00

abstract：:The polyphenol curcumin (diferuloylmethane) is the active componenet of the spice plant Curcuma longa and has been shown to exert multiple actions on mammalian cells. We have studied its effect on folliculostellate (FS) TtT/GF mouse pituitary cells, representative of a multifunctional, endocrine inactive cell type of ...

journal_title：Neuroendocrinology

authors： Schaaf C,Shan B,Onofri C,Stalla GK,Arzt E,Schilling T,Perone MJ,Renner U

更新日期：2010-01-01 00:00:00

abstract：:The presence of vasopressin (VP) in pars distalis of rats and pigs was investigated. Using radioimmunoassay and bioassay of VP, a substance with immunological and biological properties of this hormone was found. This substance was not detected in the adenohypophysis of rats with diabetes insipidus. A partial purificat...

journal_title：Neuroendocrinology

authors： Chateau M,Marchetti J,Burlet A,Boulange M

更新日期：1979-01-01 00:00:00

abstract：:alpha-Methyl-p-tyrosine (alpha-MT), a competitive inhibitor of tyrosine hydroxylase, was used to block the synthesis of hypothalamic catecholamines in immature female rats of 14, 16 and 30 days of age and in castrated adults. The administration of alpha-MT (300 mg/kg body weight, free base) induced a significant decay...

journal_title：Neuroendocrinology

authors： Moguilevsky JA,Arias P,Szwarcfarb B,Carbone S,Rondina D

更新日期：1990-10-01 00:00:00

abstract：:Endogenous gonadoliberin was localized by using immunocytological methods in the hypothalamic neurons which synthetize the peptide and in the hypophysial target cells. The rat tissues were fixed and frozen. Ultrathin sections were obtained by cryoultramicrotomy. In the pituitary gland, GnRH was observed in both gonado...

journal_title：Neuroendocrinology

authors： Morel G,Dubois PM

更新日期：1982-03-01 00:00:00

abstract：:The injection of purified alpha-bungarotoxin (alpha-BTX), an antagonist of the muscle nicotinic cholinergic receptors, into the third ventricle (3rd V) of ovariectomized rats decreased the frequency of pulses of luteinizing hormone (LH) but had no significant effect on the amplitude or nadir of LH secretion. Approxima...

journal_title：Neuroendocrinology

authors： Kalash J,Romita V,Billiar RB

更新日期：1989-05-01 00:00:00

abstract：:Hypothalamic dopamine (DA) tonically inhibits prolactin (PRL) release from the anterior pituitary gland. Transient escapes from this DA tone elicit a pronounced potentiation of the PRL-releasing action of secretagogues such as thyrotropin-releasing hormone (TRH). Previous evidence has suggested that modulation of Ca(2...

journal_title：Neuroendocrinology

authors： del Mar Hernández M,García Ferreiro RE,García DE,Hernández ME,Clapp C,Martínez de la Escalera G

更新日期：1999-07-01 00:00:00

abstract：:Progesterone is readily reduced in humans to its A-ring metabolites, allopregnanolone (3 alpha-hydroxy-5 alpha-pregnan-20-one) and pregnanolone (3 alpha-hydroxy-5 beta-pregnan-20-one). The latter have been reported to have anxiolytic, hypnotic and anesthetic actions when administered to laboratory animals and (or) hum...

journal_title：Neuroendocrinology

authors： Freeman EW,Purdy RH,Coutifaris C,Rickels K,Paul SM

更新日期：1993-10-01 00:00:00

abstract：:Rats bearing transplanted prolactin-secreting tumors are known to have very high prolactin levels in the serum, reduced hypothalamic opiate concentrations, increasing hypothalamic dopamine synthesis and increased hypophyseal portal blood dopamine levels. Further, it has been shown that incubation in 3H-leucine of ante...

journal_title：Neuroendocrinology

authors： Login IS,Nagy I,MacLeod RM

更新日期：1981-08-01 00:00:00

abstract：:Correlations between the specific binding of radiolabelled adrenoligands in frontal cortex and hypothalamus, and plasma testosterone levels were investigated in inbred mouse strains. Binding values were structure and genotype dependent. There were significant negative intrastrain and interstrain correlations between h...

journal_title：Neuroendocrinology

authors： Shishkina GT,Naumenko EV

更新日期：1995-06-01 00:00:00

abstract：:In previous studies we obtained evidence that serotonin release by p-chloroamphetamine (PCA) causes an increase in corticosterone secretion but that this effect is not mediated via the raphe nuclei in the midbrain. In contrast, PCA-induced prolactin secretion was abolished by dorsal raphe lesions. In the present study...

journal_title：Neuroendocrinology

authors： Van de Kar LD,Karteszi M,Bethea CL,Ganong WF

更新日期：1985-11-01 00:00:00

abstract：:Tissue-specific stem cells are uncovered in a growing number of organs by their molecular expression profile and their potential for self-renewal, multipotent differentiation and tissue regeneration. Whether the pituitary gland also contains a pool of versatile 'master' cells that drive homeostatic, plastic and regene...

journal_title：Neuroendocrinology

authors： Vankelecom H

更新日期：2007-01-01 00:00:00

abstract：:An abolishment of 24 h periodicity of the adrenocortical activity was observed in rats subjected to a prolonged food deprivation of 7--8 days. Total locomotor activity progressively decreased and its circadian rhythm faded out in a similar fashion as the adrenocortical rhythm. The circadian rhythms of both locomotor a...

journal_title：Neuroendocrinology

authors： Kobayashi K,Takahashi K

更新日期：1979-01-01 00:00:00

abstract：:This study was carried out to clarify the central effects of neuropeptide Y (NPY) on gonadotropin and prolactin (PRL) release in the male rat and to evaluate the hypothesis that it may play a role in negative feedback regulation of gonadotropin secretion in the male. NPY (4 micrograms in 2 microliters 0.9% NaCl) or an...

journal_title：Neuroendocrinology

authors： Reznikov AG,McCann SM

更新日期：1993-06-01 00:00:00