Comparative aspects of GH and metabolic regulation in lower vertebrates.

Abstract:

:In all vertebrates, the regulations of growth and energy balance are complex phenomena which involve elaborate interactions between the brain and peripheral signals. Most vertebrates adopt and maintain a life style after birth, but lower vertebrates may have complex life histories involving metamorphoses, migrations and long periods of fasting. In order to achieve the complex developmental programs associated with these changes, coordinated regulation of all aspects of energy metabolism is required. Somatotropic axis (somatostatin (SRIH) growth hormone (GH) and insulin-like growth factor 1 (IGF1), is known to be involved in the regulation of growth and energy balance. Interestingly, recent studies showed that additional factors such as pituitary adenylate cyclase-activated polypeptide (PACAP), corticotropin-releasing hormone (CRH), ghrelin and leptin could also have major roles in the control of growth and metabolism in lower vertebrates (fish, amphibians and reptiles). This mini-review will survey the function of GH and metabolic regulation in lower vertebrates.

journal_name

Neuroendocrinology

journal_title

Neuroendocrinology

authors

Rousseau K,Dufour S

doi

10.1159/000101029

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

165-74

issue

3

eissn

0028-3835

issn

1423-0194

pii

000101029

journal_volume

86

pub_type

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