Abstract:
PURPOSE:A MR thermometry (MRT) method with field monitoring is proposed to improve the measurement of small temperature variations induced in brain MRI exams. METHODS:MR thermometry experiments were performed at 7 Tesla with concurrent field monitoring and RF heating. Images were reconstructed with nominal k-space trajectories and with first-order spherical harmonics correction. Experiments were performed in vitro with deliberate field disturbances and on an anesthetized macaque in 2 different specific absorption rate regimes, that is, at 50% and 100% of the maximal specific absorption rate level allowed in the International Electrotechnical Commission normal mode of operation. Repeatability was assessed by running a second separate session on the same animal. RESULTS:Inclusion of magnetic field fluctuations in the reconstruction improved temperature measurement accuracy in vitro down to 0.02°C. Measurement precision in vivo was on the order of 0.15°C in areas little affected by motion. In the same region, temperature increase reached 0.5 to 0.8°C after 20 min of heating at 100% specific absorption rates and followed a rough factor of 2 with the 50% specific absorption rate scans. A horizontal temperature plateau, as predicted by Pennes bioheat model with thermal constants from the literature and constant blood temperature assumption, was not observed. CONCLUSION:Inclusion of field fluctuations in image reconstruction was beneficial for the measurement of small temperature rises encountered in standard brain exams. More work is needed to correct for motion-induced field disturbances to extract reliable temperature maps.
journal_name
Magn Reson Medjournal_title
Magnetic resonance in medicineauthors
Le Ster C,Mauconduit F,Mirkes C,Bottlaender M,Boumezbeur F,Djemai B,Vignaud A,Boulant Ndoi
10.1002/mrm.28501subject
Has Abstractpub_date
2021-03-01 00:00:00pages
1282-1293issue
3eissn
0740-3194issn
1522-2594journal_volume
85pub_type
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