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Depressive state and chronic fatigue in multiple sclerosis and neuromyelitis optica.

Abstract：

:Depression and chronic fatigue are frequently present in multiple sclerosis (MS); however, the prevalence rates have not been investigated in neuromyelitis optica (NMO). Thirty-nine consecutive NMO and 75 MS patients were compared using self-rating questionnaires for depressive states, daily activity, and fatigue, as well as serum carnitine levels. A subgroup of patients with low carnitine levels were re-evaluated regarding depression and fatigue after levocarnitine treatment. Depression and fatigue were equally prevalent in MS and NMO and were strongly correlated with one another. Measurement of the serum carnitine levels and the administration of levocarnitine did not appear to be beneficial.

journal_name

J Neuroimmunol

journal_title

Journal of neuroimmunology

authors

Akaishi T,Nakashima I,Misu T,Fujihara K,Aoki M

doi

10.1016/j.jneuroim.2015.05.007

subject

Has Abstract

pub_date

2015-06-15 00:00:00

pages

70-3

eissn

0165-5728

issn

1872-8421

pii

S0165-5728(15)00119-8

journal_volume

283

pub_type

杂志文章

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