Should "suspicious for high-grade urothelial carcinoma" and "positive for high-grade urothelial carcinoma" remain separate categories?

abstract：BACKGROUND:Accurate fine-needle aspiration (FNA) diagnosis of metastatic melanoma is of therapeutic and prognostic significance and often requires ancillary studies. To the authors' knowledge, the reliability of immunostaining using a pan-melanoma cocktail, Sry-related HMG-BOX gene 10 (SOX10), and microphthalmia transc...

journal_title：Cancer cytopathology

authors： Clevenger J,Joseph C,Dawlett M,Guo M,Gong Y

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Adequacy assessment is one of the most controversial and overlooked components in the daily practice of cytopathology, because it is generally determined from limited samples. Because voided urine varies widely in terms of its volume and cellularity, there is little consensus about the proper role for these ...

journal_title：Cancer cytopathology

authors： VandenBussche CJ,Rosenthal DL,Olson MT

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma (ES) is a rare mesenchymal tumor that is divided into 2 types: classic and proximal. To the authors' knowledge, ES has been poorly studied in cytology, with fewer than 50 cases reported to date. The objective of the current study was to analyze the cytological and immunohistochemical info...

journal_title：Cancer cytopathology

authors： Gajdzis P,Laé M,Klijanienko J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Much of the reluctance about using cytology specimens rather than histology specimens to assess programmed death ligand 1 (PD-L1) expression for guiding the use of immune modulating drugs in the management of non-small cell lung cancer (NSCLC) is based on the belief that the alcohol-based fixatives favored b...

journal_title：Cancer cytopathology

authors： Gosney JR,Haragan A,Chadwick C,Giles TE,Grundy S,Tippett V,Gumparthy KP,Wight A,Tan HG

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the diagnostic accuracy of the Bladder EpiCheck test in the follow-up of patients with non-muscle-invasive bladder cancer (NMIBC) and to compare it with the accuracy of urinary cytology, cystoscopy, and/or histology. METHODS:In total, 243 patients were enrolled in...

journal_title：Cancer cytopathology

authors： Trenti E,D'Elia C,Mian C,Schwienbacher C,Hanspeter E,Pycha A,Kafka M,Degener S,Danuser H,Roth S,Pycha A

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Germline and somatic mutations of DICER1 have been identified in various types of neoplastic lesions, with germline DICER1 mutation being linked to autosomal dominant hereditary pleiotropic tumor syndrome (DICER1 syndrome). Patients with DICER1 syndrome are at increased risk of developing thyroid disease, in...

journal_title：Cancer cytopathology

authors： Darbinyan A,Morotti R,Cai G,Prasad ML,Christison-Lagay E,Dinauer C,Adeniran AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The Paris System for Reporting Urinary Cytology (TPS) defines clear morphologic criteria to classify urinary specimens into 7 diagnostic categories. According to TPS, a nuclear-to-cytoplasmic ratio (N:C ratio) >0.7 and hyperchromasia must be observed to render a diagnosis of high-grade urothelial carcinoma (...

journal_title：Cancer cytopathology

authors： Richardson CJ,Pambuccian SE,Barkan GA

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Tumor spread through air spaces (STAS), a significant prognostic indicator, has been described recently as a pattern of invasion in pulmonary carcinomas. However, questions remain regarding preoperative identification of STAS and whether it represents an in vivo phenomenon versus an ex vivo artifact. METHOD...

journal_title：Cancer cytopathology

authors： Medina MA,Onken AM,de Margerie-Mellon C,Heidinger BH,Chen Y,Bankier AA,VanderLaan PA

更新日期：2020-04-01 00:00:00

abstract：:Follicular cell-derived carcinomas of the thyroid gland comprise a heterogeneous group of malignant neoplasms of the thyroid gland with varied histologic appearance and molecular profiles. In most patients, these tumors represent relatively indolent neoplasms; however, certain subtypes/variants behave in an aggressive...

journal_title：Cancer cytopathology

authors： Lastra RR,LiVolsi VA,Baloch ZW

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:New developments in the treatment of lung cancer have necessitated the further histologic and cytologic subtyping of nonsmall cell lung carcinomas. Thyroid transcription factor-1 (TTF-1) long has served as the predominant marker for demonstrating lung origin. However, it is also expressed in a variety of oth...

journal_title：Cancer cytopathology

authors： Stoll LM,Johnson MW,Gabrielson E,Askin F,Clark DP,Li QK

更新日期：2010-12-25 00:00:00

abstract：BACKGROUND:The Papanicolaou Society of Cytopathology has recently published a new proposal for pancreaticobiliary cytology terminology. For the current study, the authors applied this new classification for pancreaticobiliary cytology to a set of previously diagnosed endoscopic ultrasound (EUS)-guided fine-needle aspir...

journal_title：Cancer cytopathology

authors： Saieg MA,Munson V,Colletti S,Nassar A

更新日期：2015-08-01 00:00:00

abstract：:Cervical cancer and anal cancer share many similarities including causation by oncogenic human papillomaviruses; however, significant differences exist in their epidemiology, risk factors, biologic behavior, management, and treatment. Although rare, the incidence of anal cancer is alarmingly high and continues to incr...

journal_title：Cancer cytopathology

authors： Darragh TM,Winkler B

更新日期：2011-02-25 00:00:00

abstract：BACKGROUND:The authors conducted an analysis of 2 telepathology systems with different resolutions to determine how resolution affects the pathologists' ability to provide preliminary diagnoses for fine-needle aspirations (FNA). METHODS:FNA cases evaluated by telepathology between February 1, 2011 and January 18, 2012...

journal_title：Cancer cytopathology

authors： McMahon RQ,McCarthy EE,Hetzel SJ,Das K,Stewart J 3rd

更新日期：2014-07-01 00:00:00

abstract：:Ocular cytology specimens are small, with limited options for a repeat biopsy. Appropriate handling of these specimens and triaging for ancillary testing can be taxing. In this article, the author reviews a selection of potentially challenging diagnoses and current common practices and methods used in diagnosing ocula...

journal_title：Cancer cytopathology

authors： Laver NMV

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:Current immunohistochemical and in situ hybridization (ISH) assays are generally inconclusive for clonality unless plasmacytic differentiation is present. This study examined a series of cytology specimens and explored the ability of a branched-chain RNA (bRNA) ISH assay for immunoglobulin κ constant (IGKC) ...

journal_title：Cancer cytopathology

authors： Arora K,Chebib I,Zukerberg L,Gandhi M,Rivera M,Ting D,Deshpande V

更新日期：2016-03-01 00:00:00

abstract：:In diagnostic cytology, the known site-specific false positive rates at various anatomical sites for the risk malignancy (ROM) when a confirmed malignant diagnosis is made are comparatively well documented. ROM figures for diagnostic cytology specimens may vary according to the anatomical site of the specimen, the exa...

journal_title：Cancer cytopathology

authors： Poller DN,Schmitt F

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Personalized oncology requires molecular analysis of tumor cells. Several studies have demonstrated that cytological material is suitable for DNA analysis, but to the authors' knowledge there are no systematic studies comparing how the yield and quality of extracted DNA is affected by the various techniques ...

journal_title：Cancer cytopathology

authors： Dejmek A,Zendehrokh N,Tomaszewska M,Edsjö A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Morphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated. METHODS:Thyroid fine-needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extra...

journal_title：Cancer cytopathology

authors： Heymann JJ,Yoxtheimer LM,Park HJ,Fernandez EM,Facey KE,Alperstein SA,Tran HV,Baek I,Scognamiglio T,Rennert H,Siddiqui MT,Song W

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The usefulness of GATA3 (GATA-binding protein 3 to DNA sequence [A/T]GATA[A/G]) as a marker for metastatic breast carcinoma in serous effusion specimens was investigated. METHODS:Cell block sections from 74 serous effusion specimens (32 ascitic, 2 pericardial, and 40 pleural fluids) were stained with an ant...

journal_title：Cancer cytopathology

authors： Shield PW,Papadimos DJ,Walsh MD

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Carbonic anhydrase IX (CAIX) is a hallmark of metabolic change in cancer cells. The aim was to evaluate the utility of CAIX expression for the detection of malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry. METHODS:A total of 97 pleural effusions including 54 b...

journal_title：Cancer cytopathology

authors： Liao ND,Lee WY

更新日期：2012-08-25 00:00:00

abstract：BACKGROUND:Transbronchial needle aspiration (TBNA) of peripheral lung nodules can be difficult with conventional devices due to their limited flexibility. A promising new technology for accessing these lesions is the PeriView FLEX TBNA device, which has a flexible spiral-grooved needle. The present study reports the un...

journal_title：Cancer cytopathology

authors： Naso J,Bras J,Villamil C,Ionescu DN,Wang G,Shaipanich T,Beaudoin EL,Myers R,Lam S,Zhou C

更新日期：2020-05-01 00:00:00

abstract：:The American Society of Cytopathology has provided guidelines for goals and objectives for cytopathology fellows. There are 90 Accreditation Council for Graduate Medical Education-accredited cytopathology fellowship training programs in the United States, each with its own unique curriculum designed to achieve these g...

journal_title：Cancer cytopathology

authors： Naritoku WY,Black-Schaffer WS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The newly unveiled Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has proposed salivary gland neoplasm of uncertain malignant potential (SUMP) as an indeterminate category. The category is reserved for fine-needle aspiration (FNA) cases that are diagnostic of a salivary gland neoplasm but c...

journal_title：Cancer cytopathology

authors： Hang JF,Alruwaii F,Zeng BR,Lai CR,Wu HH

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Limited studies have examined the impact of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and specifically the category of atypia or follicular lesion of undetermined significance (AUS/FLUS). We studied their effects on reporting rates, subsequent management, and surgical outcome over a 10-...

journal_title：Cancer cytopathology

authors： Sullivan PS,Hirschowitz SL,Fung PC,Apple SK

更新日期：2014-12-01 00:00:00

abstract：:The recent emergence of immune checkpoint inhibitors for cancer therapy has created much excitement among cancer patients, drug and diagnostic developers, and health care professionals. This is due largely to the dramatic and sustained responses among some advanced cancers that were previously refractory to therapy. U...

journal_title：Cancer cytopathology

authors： Clark DP

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The Milan System for Reporting Salivary Gland Cytopathology is a tiered classification scheme that includes 6 diagnostic categories. Neoplasm, which is 1 of the 6 proposed categories, consists of benign neoplasm and neoplasm of uncertain malignant potential (NUMP). NUMP is reserved for a salivary gland neopl...

journal_title：Cancer cytopathology

authors： Liu H,Ljungren C,Lin F,Zarka MA,Chen L

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Urine cytology results that are suspicious for urothelial carcinoma (UC) are challenging. The objective of this study was to elucidate the clinical significance of such results in patients who have a negative cystoscopy. METHODS:In this prospective study, 83 patients who had urine cytology that was suspicio...

journal_title：Cancer cytopathology

authors： Montalbo R,Izquierdo L,Ingelmo-Torres M,Galve P,Solé M,Franco A,Ribal MJ,Alcaraz A,Mengual L

更新日期：2020-07-01 00:00:00

abstract：:BACKGROUND.: Pancreatic ductal adenocarcinoma is rarely detected early enough for patients to be cured. The objective of the authors was to develop a monoclonal antibody to distinguish adenocarcinoma and precancerous intraductal papillary mucinous neoplasia (IPMN) from benign epithelium. METHODS.: Mice were immunized ...

journal_title：Cancer cytopathology

authors： Morgan TK,Hardiman K,Corless CL,White SL,Bonnah R,Van de Vrugt H,Sheppard BC,Grompe M,Cosar EF,Streeter PR

更新日期：2013-01-01 00:00:00

abstract：:An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multi...

journal_title：Cancer cytopathology

authors： Renshaw AA,Gould EW

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) tests and genotyping have been used in clinical risk assessment. The purpose of this study was to analyze the performance of 2 common HPV testing platforms in detecting high-grade cervical lesions (high-grade squamous intraepithelial lesion [HSIL] or worse [≥HSIL]). METHODS:Betwee...

journal_title：Cancer cytopathology

authors： Ge Y,Christensen P,Luna E,Armylagos D,Schwartz MR,Mody DR

更新日期：2017-08-01 00:00:00