Analysis of histologic follow-up and risk of malignancy for salivary gland neoplasm of uncertain malignant potential proposed by the Milan System for Reporting Salivary Gland Cytopathology.

abstract：BACKGROUND:Morphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated. METHODS:Thyroid fine-needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extra...

journal_title：Cancer cytopathology

authors： Heymann JJ,Yoxtheimer LM,Park HJ,Fernandez EM,Facey KE,Alperstein SA,Tran HV,Baek I,Scognamiglio T,Rennert H,Siddiqui MT,Song W

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Mutations of AT-rich interactive domain 1 (ARID1A) have been associated with a worse outcome after intravesical treatment with bacille Calmette-Guérin in patients with non-muscle-invasive bladder cancer (NMIBC). Loss of ARID1A protein expression in urine cytology may serve as an indication of an ARID1A mutat...

journal_title：Cancer cytopathology

authors： Dugas SG,Müller DC,Le Magnen C,Federer-Gsponer J,Seifert HH,Ruiz C,Savic Prince S,Vlajnic T,Zellweger T,Mertz KD,Bacon JVW,Wyatt AW,Rentsch CA,Bubendorf L

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Subtyping non-small cell lung carcinomas (NSCLC) into adenocarcinoma (ACA) or squamous cell carcinoma (SQCC) is important for treatment and specimen triage for molecular studies. To preserve tissue for molecular studies in cytology/small biopsy specimens, a 2-antibody cocktail for NSCLC subtyping was develop...

journal_title：Cancer cytopathology

authors： Nishino M,Hoang MP,Della Pelle P,Morales-Oyarvide V,Huynh TG,Mark EJ,Mino-Kenudson M

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The Bethesda System for Reporting Thyroid Cytopathology category of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) includes fine-needle aspiration (FNA) specimens that cannot straightforwardly be classified as benign or malignant. To determine whether morphologi...

journal_title：Cancer cytopathology

authors： Bellevicine C,Sgariglia R,Migliatico I,Vigliar E,D'Anna M,Nacchio MA,Serra N,Malapelle U,Bongiovanni M,Troncone G

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess how atypical diagnostic category (ADC) is followed up, its outcomes, and the predictors that are associated with subsequent diagnosis of neoplasm/malignancy. METHODS:We reviewed pancreatic endoscopic ultrasound fine-needle aspiration (EUS-FNA) with ADC and compared ...

journal_title：Cancer cytopathology

authors： Alston E,Bae S,Eltoum IA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Germline and somatic mutations of DICER1 have been identified in various types of neoplastic lesions, with germline DICER1 mutation being linked to autosomal dominant hereditary pleiotropic tumor syndrome (DICER1 syndrome). Patients with DICER1 syndrome are at increased risk of developing thyroid disease, in...

journal_title：Cancer cytopathology

authors： Darbinyan A,Morotti R,Cai G,Prasad ML,Christison-Lagay E,Dinauer C,Adeniran AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The 2007 Bethesda classification for thyroid cytology defines follicular neoplasm as a category of cases with cellular specimens demonstrating abundant follicular cells arranged in a microfollicular pattern with little or no colloid. The current recommendation for the management of these cases is diagnostic ...

journal_title：Cancer cytopathology

authors： Ustun B,Chhieng D,Van Dyke A,Carling T,Holt E,Udelsman R,Adeniran AJ

更新日期：2014-07-01 00:00:00

abstract：:The recent emergence of immune checkpoint inhibitors for cancer therapy has created much excitement among cancer patients, drug and diagnostic developers, and health care professionals. This is due largely to the dramatic and sustained responses among some advanced cancers that were previously refractory to therapy. U...

journal_title：Cancer cytopathology

authors： Clark DP

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Personalized oncology requires molecular analysis of tumor cells. Several studies have demonstrated that cytological material is suitable for DNA analysis, but to the authors' knowledge there are no systematic studies comparing how the yield and quality of extracted DNA is affected by the various techniques ...

journal_title：Cancer cytopathology

authors： Dejmek A,Zendehrokh N,Tomaszewska M,Edsjö A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The Paris System (TPS) for Reporting Urinary Cytology aims to standardize urine cytology reporting. Per TPS, the diagnosis of "suspicious for high-grade urothelial carcinoma (SHGUC)" is applied in cases that have few urothelial cells with severe atypia but are quantitatively insufficient for a diagnosis of "...

journal_title：Cancer cytopathology

authors： Nguyen L,Nilforoushan N,Krane JF,Bose S,Bakkar R

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the diagnostic accuracy of the Bladder EpiCheck test in the follow-up of patients with non-muscle-invasive bladder cancer (NMIBC) and to compare it with the accuracy of urinary cytology, cystoscopy, and/or histology. METHODS:In total, 243 patients were enrolled in...

journal_title：Cancer cytopathology

authors： Trenti E,D'Elia C,Mian C,Schwienbacher C,Hanspeter E,Pycha A,Kafka M,Degener S,Danuser H,Roth S,Pycha A

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy of spindled mesenchymal lesions, including schwannomas, are challenging because of overlapping cytomorphological features. The objective of the current study was to identify key diagnostic cytological criteria for the diagnosis of schwannoma and to distinguish it from its common...

journal_title：Cancer cytopathology

authors： Chebib I,Hornicek FJ,Nielsen GP,Deshpande V

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:The authors conducted an analysis of 2 telepathology systems with different resolutions to determine how resolution affects the pathologists' ability to provide preliminary diagnoses for fine-needle aspirations (FNA). METHODS:FNA cases evaluated by telepathology between February 1, 2011 and January 18, 2012...

journal_title：Cancer cytopathology

authors： McMahon RQ,McCarthy EE,Hetzel SJ,Das K,Stewart J 3rd

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Liquid-based cytology (LBC) is a useful cytopathological method, and LBC lung adenocarcinoma specimens may be used for genetic analysis in the near future. In the current study, the authors determined whether LBC specimens can be used for epidermal growth factor receptor (EGFR) mutation analysis in human lun...

journal_title：Cancer cytopathology

authors： Matsuo Y,Yoshida T,Yamashita K,Satoh Y

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Homozygous deletion of 9p21 detected by fluorescence in situ hybridization (FISH) and loss of BRCA1-associated protein 1 (BAP1) expression detected by immunohistochemistry (IHC) are useful for the differentiation between malignant pleural mesothelioma (MPM) and reactive mesothelial hyperplasia. The authors p...

journal_title：Cancer cytopathology

authors： Kinoshita Y,Hida T,Hamasaki M,Matsumoto S,Sato A,Tsujimura T,Kawahara K,Hiroshima K,Oda Y,Nabeshima K

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Carbonic anhydrase IX (CAIX) is a hallmark of metabolic change in cancer cells. The aim was to evaluate the utility of CAIX expression for the detection of malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry. METHODS:A total of 97 pleural effusions including 54 b...

journal_title：Cancer cytopathology

authors： Liao ND,Lee WY

更新日期：2012-08-25 00:00:00

abstract：BACKGROUND:Diagnosing giant cell-rich bone tumors can be challenging on limited biopsies. H3 histone family member 3A (H3F3A) (G34W/V/R/L) mutations are present in the majority of giant cell tumors (GCTs) of bone and H3 histone family member 3B (H3F3B) (K36M) mutations are present in nearly all chondroblastomas, but ar...

journal_title：Cancer cytopathology

authors： Schaefer IM,Fletcher JA,Nielsen GP,Shih AR,Ferrone ML,Hornick JL,Qian X

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Epithelioid sarcoma (ES) is a rare mesenchymal tumor that is divided into 2 types: classic and proximal. To the authors' knowledge, ES has been poorly studied in cytology, with fewer than 50 cases reported to date. The objective of the current study was to analyze the cytological and immunohistochemical info...

journal_title：Cancer cytopathology

authors： Gajdzis P,Laé M,Klijanienko J

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Urine cytology has been used for screening of bladder cancer but has been limited by its low sensitivity. UroVysion is a multiprobe fluorescence in situ hybridization (FISH) assay that detects common chromosome abnormalities in bladder cancers. For this study, the authors evaluated the effectiveness of multi...

journal_title：Cancer cytopathology

authors： Dimashkieh H,Wolff DJ,Smith TM,Houser PM,Nietert PJ,Yang J

更新日期：2013-10-01 00:00:00

abstract：:The American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines for the management of women with abnormal cervical screening test results is a powerful, evidence-based document representing an advance in the consistent treatment of women with cervical abnormalities. Nevertheless, the complexity of the gu...

journal_title：Cancer cytopathology

authors： Colgan TJ

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:High-risk human papillomavirus (hrHPV) DNA detection is generally accepted for the triage of women with a cytologic diagnosis of atypical squamous cells of undetermined significance (ASC-US). However, no consensus has been reached on the optimal management of low-grade squamous intraepithelial lesions (LSIL)...

journal_title：Cancer cytopathology

authors： Verdoodt F,Szarewski A,Halfon P,Cuschieri K,Arbyn M

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Much of the reluctance about using cytology specimens rather than histology specimens to assess programmed death ligand 1 (PD-L1) expression for guiding the use of immune modulating drugs in the management of non-small cell lung cancer (NSCLC) is based on the belief that the alcohol-based fixatives favored b...

journal_title：Cancer cytopathology

authors： Gosney JR,Haragan A,Chadwick C,Giles TE,Grundy S,Tippett V,Gumparthy KP,Wight A,Tan HG

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to investigate the clinical performance of detecting high-grade lesions with the CINtec PLUS p16(INK4a)/Ki-67 dual stain and the APTIMA human papillomavirus (HPV) Assay in a cohort of women with low-grade squamous intraepithelial lesion (LSIL) cytology. The authors also...

journal_title：Cancer cytopathology

authors： Waldstrøm M,Christensen RK,Ørnskov D

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The primary goal of this study was to compare the clinical performance of an optimized and rigorously controlled immunocytochemical (ICC) assay for p16(INK4a) to high-risk (HR) human papillomavirus (HPV) detection by polymerase chain reaction (PCR) as diagnostic adjuncts for cytology specimens from colposcop...

journal_title：Cancer cytopathology

authors： Samarawardana P,Dehn DL,Singh M,Franquemont D,Thompson C,Gaido L,Torkko KC,Homer P,Burke S,Titmus MA,Nayi V,Shroyer KR

更新日期：2010-06-25 00:00:00

abstract：:An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multi...

journal_title：Cancer cytopathology

authors： Renshaw AA,Gould EW

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The separation of benign from malignant mesothelial proliferations on effusion cytology can be difficult. Loss of methylthioadenosine phosphorylase (MTAP) by immunohistochemistry is an established marker of malignancy in mesothelial proliferations, but to the authors' knowledge largely has been applied only ...

journal_title：Cancer cytopathology

authors： Berg KB,Churg AM,Cheung S,Dacic S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:p16(INK4a) Is overexpressed in almost all precancerous and carcinomatous lesions of the uterine cervix, secondary to interference between high-risk human papillomaviruses (hr-HPVs) and the retinoblastoma gene product. Overexpression of p16(INK4a) has also been identified in patients with high-grade urothelia...

journal_title：Cancer cytopathology

authors： Piaton E,Casalegno JS,Advenier AS,Decaussin-Petrucci M,Mege-Lechevallier F,Ruffion A,Mekki Y

更新日期：2014-10-01 00:00:00

abstract：:The 8th Annual National Molecular Cytopathology Meeting, held in Naples, Italy, on December 2 to 3, 2019, addressed updates in diagnostic cytopathology and molecular classifications and specifically focused on lung cancer biomarker testing in cytology samples. Lung cancer continues to be the most commonly diagnosed no...

journal_title：Cancer cytopathology

authors： Rossi ED,Wiles A,Vecchione A

更新日期：2020-09-01 00:00:00

abstract：:Ocular cytology specimens are small, with limited options for a repeat biopsy. Appropriate handling of these specimens and triaging for ancillary testing can be taxing. In this article, the author reviews a selection of potentially challenging diagnoses and current common practices and methods used in diagnosing ocula...

journal_title：Cancer cytopathology

authors： Laver NMV

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:Tumor spread through air spaces (STAS), a significant prognostic indicator, has been described recently as a pattern of invasion in pulmonary carcinomas. However, questions remain regarding preoperative identification of STAS and whether it represents an in vivo phenomenon versus an ex vivo artifact. METHOD...

journal_title：Cancer cytopathology

authors： Medina MA,Onken AM,de Margerie-Mellon C,Heidinger BH,Chen Y,Bankier AA,VanderLaan PA

更新日期：2020-04-01 00:00:00