p16(INK4a) overexpression is not linked to oncogenic human papillomaviruses in patients with high-grade urothelial cancer cells.

abstract：BACKGROUND:Limited studies have examined the impact of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and specifically the category of atypia or follicular lesion of undetermined significance (AUS/FLUS). We studied their effects on reporting rates, subsequent management, and surgical outcome over a 10-...

journal_title：Cancer cytopathology

authors： Sullivan PS,Hirschowitz SL,Fung PC,Apple SK

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:BRAF mutations are highly specific for papillary thyroid carcinoma (PTC) and many cytology specimens with BRAF mutations are expected to demonstrate cytologic features typical of PTC. However, indeterminate thyroid cytology cases are inevitable and understanding the significance of the BRAF mutation within t...

journal_title：Cancer cytopathology

authors： Ohori NP,Singhal R,Nikiforova MN,Yip L,Schoedel KE,Coyne C,McCoy KL,LeBeau SO,Hodak SP,Carty SE,Nikiforov YE

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the diagnostic value of cell block (CB) as an adjunct to ThinPrep liquid-based cytology (LBC) of bronchial washing specimens in the detection and subclassification of pulmonary neoplasms has not been well evaluated. The objective of the current study was to evaluate the diagnostic ...

journal_title：Cancer cytopathology

authors： Collins GR,Thomas J,Joshi N,Zhang S

更新日期：2012-04-25 00:00:00

abstract：:An increasing number of renal cell carcinomas (RCCs) require ancillary studies for diagnosis. The majority of renal fine needle aspirates do not require ancillary studies. Among the most common useful stains are cytokeratin 7 (separating clear cell RCC [negative] from papillary RCC, clear cell papillary RCC, and multi...

journal_title：Cancer cytopathology

authors： Renshaw AA,Gould EW

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Urine cytology has been used for screening of bladder cancer but has been limited by its low sensitivity. UroVysion is a multiprobe fluorescence in situ hybridization (FISH) assay that detects common chromosome abnormalities in bladder cancers. For this study, the authors evaluated the effectiveness of multi...

journal_title：Cancer cytopathology

authors： Dimashkieh H,Wolff DJ,Smith TM,Houser PM,Nietert PJ,Yang J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Germline and somatic mutations of DICER1 have been identified in various types of neoplastic lesions, with germline DICER1 mutation being linked to autosomal dominant hereditary pleiotropic tumor syndrome (DICER1 syndrome). Patients with DICER1 syndrome are at increased risk of developing thyroid disease, in...

journal_title：Cancer cytopathology

authors： Darbinyan A,Morotti R,Cai G,Prasad ML,Christison-Lagay E,Dinauer C,Adeniran AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Subtyping non-small cell lung carcinomas (NSCLC) into adenocarcinoma (ACA) or squamous cell carcinoma (SQCC) is important for treatment and specimen triage for molecular studies. To preserve tissue for molecular studies in cytology/small biopsy specimens, a 2-antibody cocktail for NSCLC subtyping was develop...

journal_title：Cancer cytopathology

authors： Nishino M,Hoang MP,Della Pelle P,Morales-Oyarvide V,Huynh TG,Mark EJ,Mino-Kenudson M

更新日期：2016-07-01 00:00:00

abstract：:A pediatric cytopathology symposium was held at the recent 20th International Congress of Cytology, which convened in Sydney, Australia, in May 2019. This educational event brought together cytopathologists from different countries and different institutions to discuss some of the practical considerations when applyin...

journal_title：Cancer cytopathology

authors： Monaco SE,Baloch ZW,Rossi ED,Teot LA,Wright C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration of the thyroid is a common procedure, with an established role in reducing unnecessary thyroid surgery and identifying neoplasms and malignancies. METHODS:The study evaluated 1558 responses in the American Society for Clinical Pathology (ASCP) Non-GYN Assessment program of aspirates o...

journal_title：Cancer cytopathology

authors： Eilers SG,LaPolice P,Mukunyadzi P,Kapur U,Wendel Spiczka A,Shah A,Saleh H,Adeniran A,Nunez A,Balachandran I,Clark JJ,Lemon L

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The accumulation of cyclin-dependent kinase inhibitor 2A (p16ink4a ) protein in a cell is associated with neoplastic progression in precancerous cervical lesions. Dual staining for p16ink4a and Ki-67 has been proposed as a triage test in cervical cancer screening for women who test positive for human papillo...

journal_title：Cancer cytopathology

authors： Benevolo M,Allia E,Gustinucci D,Rollo F,Bulletti S,Cesarini E,Passamonti B,Giovagnoli MR,Carico E,Carozzi FM,Mongia A,Fantacci G,Confortini M,Rubino T,Fodero C,Prandi S,Marchi N,Farruggio A,Coccia A,Macrì L,Ghirin

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:The Paris System for Reporting Urinary Cytology (TPS) defines clear morphologic criteria to classify urinary specimens into 7 diagnostic categories. According to TPS, a nuclear-to-cytoplasmic ratio (N:C ratio) >0.7 and hyperchromasia must be observed to render a diagnosis of high-grade urothelial carcinoma (...

journal_title：Cancer cytopathology

authors： Richardson CJ,Pambuccian SE,Barkan GA

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Antigen retrieval, a crucial technique for immunostaining, is often carried out on formalin-fixed, paraffin-embedded (FFPE) tissue sections. The role of antigen retrieval in immunostaining of ethanol-fixed smears remains unclear. The authors evaluated the effects of 2 common antigen retrieval procedures, hea...

journal_title：Cancer cytopathology

authors： Denda T,Kamoshida S,Kawamura J,Harada K,Kawai K,Kuwao S

更新日期：2012-06-25 00:00:00

abstract：:BACKGROUND.: Pancreatic ductal adenocarcinoma is rarely detected early enough for patients to be cured. The objective of the authors was to develop a monoclonal antibody to distinguish adenocarcinoma and precancerous intraductal papillary mucinous neoplasia (IPMN) from benign epithelium. METHODS.: Mice were immunized ...

journal_title：Cancer cytopathology

authors： Morgan TK,Hardiman K,Corless CL,White SL,Bonnah R,Van de Vrugt H,Sheppard BC,Grompe M,Cosar EF,Streeter PR

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The current study was conducted to compare DNA yield, including normalization to nuclear area, DNA amplification functionality, and detection of KRAS mutations between matched fine-needle aspiration (FNA) specimens and pancreatic resections diagnostic of pancreatic ductal adenocarcinoma. METHODS:A retrospec...

journal_title：Cancer cytopathology

authors： Hartley CP,Mahajan AM,Selvaggi SM,Rehrauer WM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Atypical glandular cells (AGC) is a very important diagnosis in gynecological cytology. In the current study, the authors investigated the usefulness of Cellient cell blocks (CB) for characterizing AGC on Papanicolaou (Pap) tests. METHODS:A total of 148 patients with an AGC diagnosis based on Pap tests by c...

journal_title：Cancer cytopathology

authors： Xing W,Hou AY,Fischer A,Owens CL,Jiang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Mantle cell lymphoma (MCL) demonstrates cytologic features that overlap with those of other types of B-cell non-Hodgkin lymphomas (B-cell NHLs) containing small to medium-sized cells. The accurate diagnosis of MCL is important because MCL has relatively more aggressive biologic behavior and thus requires spe...

journal_title：Cancer cytopathology

authors： Zhang YH,Liu J,Dawlett M,Guo M,Sun X,Gong Y

更新日期：2014-12-01 00:00:00

abstract：:The American Society of Cytopathology has provided guidelines for goals and objectives for cytopathology fellows. There are 90 Accreditation Council for Graduate Medical Education-accredited cytopathology fellowship training programs in the United States, each with its own unique curriculum designed to achieve these g...

journal_title：Cancer cytopathology

authors： Naritoku WY,Black-Schaffer WS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The workup of a malignant effusion usually requires immunostaining with a panel of markers. Although nuclear Wilms tumor 1 (WT1) expression is widely used to detect tumors of ovarian and mesothelial origin, it is less well known that WT1 is also expressed in the cytoplasm of melanomas and mesenchymal tumors....

journal_title：Cancer cytopathology

authors： Conner JR,Cibas ES,Hornick JL,Qian X

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Allogenic hematopoietic stem cell transplantation (allo-HSCT) is a common procedure in hematological disorders and is preceded by a conditioning regimen that usually includes busulfan. The immunosuppression caused by the conditioning regimen and graft-versus-host disease prophylaxis is associated with human ...

journal_title：Cancer cytopathology

authors： Saco A,Alòs S,Esteve R,Suárez-Lledó M,Martínez C,Perez FM,Vega N,Martí C,Torne A,Ordi J,Del Pino M

更新日期：2019-06-01 00:00:00

abstract：:In diagnostic cytology, the known site-specific false positive rates at various anatomical sites for the risk malignancy (ROM) when a confirmed malignant diagnosis is made are comparatively well documented. ROM figures for diagnostic cytology specimens may vary according to the anatomical site of the specimen, the exa...

journal_title：Cancer cytopathology

authors： Poller DN,Schmitt F

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The use of topically applied hemostatic substances during surgery has become a common practice. In some cases, the material is not absorbed or induces a granulomatous reaction resulting in a pseudotumoral lesion. With imaging studies, it is not possible to differentiate this from a tumor recurrence or absces...

journal_title：Cancer cytopathology

authors： Hernández-Bonilla S,Rodríguez-García AM,Jiménez-Heffernan JA,Muñoz-Hernández P,Palacios-Lázaro E,López-Ferrer P,González-Peramato P,Vicandi B

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Urine cytology results that are suspicious for urothelial carcinoma (UC) are challenging. The objective of this study was to elucidate the clinical significance of such results in patients who have a negative cystoscopy. METHODS:In this prospective study, 83 patients who had urine cytology that was suspicio...

journal_title：Cancer cytopathology

authors： Montalbo R,Izquierdo L,Ingelmo-Torres M,Galve P,Solé M,Franco A,Ribal MJ,Alcaraz A,Mengual L

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Angiomyolipoma (AML), typically composed of smooth muscle, vessels, and fat, is generally a benign tumor in the kidneys. However, it occasionally occurs in extrarenal sites and behaves like a malignant tumor. AML is uncommonly encountered in fine-needle aspiration (FNA) samples and can cause diagnostic diffi...

journal_title：Cancer cytopathology

authors： Zhou H,Guo M,Gong Y

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The availability of suitable biospecimens is critical to the success of advanced genomic analyses. The objective of this study was to assess the sensitivity of fine-needle aspiration (FNA) compared with gross surgical sampling (GSS) from surgical specimens for the detection of somatic mutations in breast can...

journal_title：Cancer cytopathology

authors： Lee HB,Joung JG,Kim J,Lee KM,Ryu HS,Lee HO,Moon HG,Park WY,Noh DY,Han W

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Personalized oncology requires molecular analysis of tumor cells. Several studies have demonstrated that cytological material is suitable for DNA analysis, but to the authors' knowledge there are no systematic studies comparing how the yield and quality of extracted DNA is affected by the various techniques ...

journal_title：Cancer cytopathology

authors： Dejmek A,Zendehrokh N,Tomaszewska M,Edsjö A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:In the United States, the rate of cervical cancer is disproportionally higher in Hispanic and Black women compared with White women. In the current study, the authors compared human papillomavirus (HPV) testing and cytology results among Black and White women over a 24-month period. They then assessed the ra...

journal_title：Cancer cytopathology

authors： Miller D,Morris CP,Maleki Z,White M,Rodriguez EF

更新日期：2020-11-01 00:00:00

abstract：:The recent emergence of immune checkpoint inhibitors for cancer therapy has created much excitement among cancer patients, drug and diagnostic developers, and health care professionals. This is due largely to the dramatic and sustained responses among some advanced cancers that were previously refractory to therapy. U...

journal_title：Cancer cytopathology

authors： Clark DP

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Adequacy assessment is one of the most controversial and overlooked components in the daily practice of cytopathology, because it is generally determined from limited samples. Because voided urine varies widely in terms of its volume and cellularity, there is little consensus about the proper role for these ...

journal_title：Cancer cytopathology

authors： VandenBussche CJ,Rosenthal DL,Olson MT

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess how atypical diagnostic category (ADC) is followed up, its outcomes, and the predictors that are associated with subsequent diagnosis of neoplasm/malignancy. METHODS:We reviewed pancreatic endoscopic ultrasound fine-needle aspiration (EUS-FNA) with ADC and compared ...

journal_title：Cancer cytopathology

authors： Alston E,Bae S,Eltoum IA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:New developments in the treatment of lung cancer have necessitated the further histologic and cytologic subtyping of nonsmall cell lung carcinomas. Thyroid transcription factor-1 (TTF-1) long has served as the predominant marker for demonstrating lung origin. However, it is also expressed in a variety of oth...

journal_title：Cancer cytopathology

authors： Stoll LM,Johnson MW,Gabrielson E,Askin F,Clark DP,Li QK

更新日期：2010-12-25 00:00:00