Ancillary studies in fine needle aspiration of the kidney.

abstract：BACKGROUND:Human papillomavirus (HPV) tests and genotyping have been used in clinical risk assessment. The purpose of this study was to analyze the performance of 2 common HPV testing platforms in detecting high-grade cervical lesions (high-grade squamous intraepithelial lesion [HSIL] or worse [≥HSIL]). METHODS:Betwee...

journal_title：Cancer cytopathology

authors： Ge Y,Christensen P,Luna E,Armylagos D,Schwartz MR,Mody DR

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) is routinely used to help clarify atypical urinary cytology. However, to the authors' knowledge, little is known regarding the frequency of chromosomal aberrations in non-neoplastic conditions that could potentially lead to false-positive FISH results. The objective ...

journal_title：Cancer cytopathology

authors： Tapia C,Glatz K,Obermann EC,Grilli B,Barascud A,Herzog M,Schönegg R,Savic S,Bubendorf L

更新日期：2011-12-25 00:00:00

abstract：BACKGROUND:The sensitivity of conventional cytology for the detection of malignant cells in pleural effusion is insufficient. GLUT1 and CAIX are the hallmarks of metabolic change in cancer cells. The aim of this study was to evaluate the usefulness of GLUT1 and CAIX expression to the detection of cancer cells in pleura...

journal_title：Cancer cytopathology

authors： Liao ND,Shieh JM,Lee WY

更新日期：2011-10-25 00:00:00

abstract：BACKGROUND:The usefulness of GATA3 (GATA-binding protein 3 to DNA sequence [A/T]GATA[A/G]) as a marker for metastatic breast carcinoma in serous effusion specimens was investigated. METHODS:Cell block sections from 74 serous effusion specimens (32 ascitic, 2 pericardial, and 40 pleural fluids) were stained with an ant...

journal_title：Cancer cytopathology

authors： Shield PW,Papadimos DJ,Walsh MD

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The Bethesda System for Reporting Thyroid Cytopathology category of atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) includes fine-needle aspiration (FNA) specimens that cannot straightforwardly be classified as benign or malignant. To determine whether morphologi...

journal_title：Cancer cytopathology

authors： Bellevicine C,Sgariglia R,Migliatico I,Vigliar E,D'Anna M,Nacchio MA,Serra N,Malapelle U,Bongiovanni M,Troncone G

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:New developments in the treatment of lung cancer have necessitated the further histologic and cytologic subtyping of nonsmall cell lung carcinomas. Thyroid transcription factor-1 (TTF-1) long has served as the predominant marker for demonstrating lung origin. However, it is also expressed in a variety of oth...

journal_title：Cancer cytopathology

authors： Stoll LM,Johnson MW,Gabrielson E,Askin F,Clark DP,Li QK

更新日期：2010-12-25 00:00:00

abstract：BACKGROUND:Morphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated. METHODS:Thyroid fine-needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extra...

journal_title：Cancer cytopathology

authors： Heymann JJ,Yoxtheimer LM,Park HJ,Fernandez EM,Facey KE,Alperstein SA,Tran HV,Baek I,Scognamiglio T,Rennert H,Siddiqui MT,Song W

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:In pediatric patients, a cutaneous nodule is usually diagnosed by performing an excisional biopsy, but fine-needle cytology (FNC) is a safer and noninvasive diagnostic method widely used to obtain diagnostic specimens with little stress to the patient. The authors compared the ability of FNC and biopsy to di...

journal_title：Cancer cytopathology

authors： Fassina A,Olivotto A,Cappellesso R,Vendraminelli R,Fassan M

更新日期：2011-04-25 00:00:00

abstract：BACKGROUND:The Paris System (TPS) for Reporting Urinary Cytology aims to standardize urine cytology reporting. Per TPS, the diagnosis of "suspicious for high-grade urothelial carcinoma (SHGUC)" is applied in cases that have few urothelial cells with severe atypia but are quantitatively insufficient for a diagnosis of "...

journal_title：Cancer cytopathology

authors： Nguyen L,Nilforoushan N,Krane JF,Bose S,Bakkar R

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The recent revision in terminology, with noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) replacing noninvasive follicular variant of papillary thyroid carcinoma, has reclassified the clinically indolent tumor as nonmalignant. The objective of this study was to evaluate th...

journal_title：Cancer cytopathology

authors： Hang JF,Westra WH,Zhou AG,Cooper DS,Ali SZ

更新日期：2018-05-01 00:00:00

abstract：:A pediatric cytopathology symposium was held at the recent 20th International Congress of Cytology, which convened in Sydney, Australia, in May 2019. This educational event brought together cytopathologists from different countries and different institutions to discuss some of the practical considerations when applyin...

journal_title：Cancer cytopathology

authors： Monaco SE,Baloch ZW,Rossi ED,Teot LA,Wright C

更新日期：2019-10-01 00:00:00

abstract：:The American Society of Cytopathology has provided guidelines for goals and objectives for cytopathology fellows. There are 90 Accreditation Council for Graduate Medical Education-accredited cytopathology fellowship training programs in the United States, each with its own unique curriculum designed to achieve these g...

journal_title：Cancer cytopathology

authors： Naritoku WY,Black-Schaffer WS

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:The use of topically applied hemostatic substances during surgery has become a common practice. In some cases, the material is not absorbed or induces a granulomatous reaction resulting in a pseudotumoral lesion. With imaging studies, it is not possible to differentiate this from a tumor recurrence or absces...

journal_title：Cancer cytopathology

authors： Hernández-Bonilla S,Rodríguez-García AM,Jiménez-Heffernan JA,Muñoz-Hernández P,Palacios-Lázaro E,López-Ferrer P,González-Peramato P,Vicandi B

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Antigen retrieval, a crucial technique for immunostaining, is often carried out on formalin-fixed, paraffin-embedded (FFPE) tissue sections. The role of antigen retrieval in immunostaining of ethanol-fixed smears remains unclear. The authors evaluated the effects of 2 common antigen retrieval procedures, hea...

journal_title：Cancer cytopathology

authors： Denda T,Kamoshida S,Kawamura J,Harada K,Kawai K,Kuwao S

更新日期：2012-06-25 00:00:00

abstract：BACKGROUND:Limited studies have examined the impact of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and specifically the category of atypia or follicular lesion of undetermined significance (AUS/FLUS). We studied their effects on reporting rates, subsequent management, and surgical outcome over a 10-...

journal_title：Cancer cytopathology

authors： Sullivan PS,Hirschowitz SL,Fung PC,Apple SK

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:High-risk human papillomavirus (hrHPV) DNA detection is generally accepted for the triage of women with a cytologic diagnosis of atypical squamous cells of undetermined significance (ASC-US). However, no consensus has been reached on the optimal management of low-grade squamous intraepithelial lesions (LSIL)...

journal_title：Cancer cytopathology

authors： Verdoodt F,Szarewski A,Halfon P,Cuschieri K,Arbyn M

更新日期：2013-12-01 00:00:00

abstract：:The American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines for the management of women with abnormal cervical screening test results is a powerful, evidence-based document representing an advance in the consistent treatment of women with cervical abnormalities. Nevertheless, the complexity of the gu...

journal_title：Cancer cytopathology

authors： Colgan TJ

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:Mutations of AT-rich interactive domain 1 (ARID1A) have been associated with a worse outcome after intravesical treatment with bacille Calmette-Guérin in patients with non-muscle-invasive bladder cancer (NMIBC). Loss of ARID1A protein expression in urine cytology may serve as an indication of an ARID1A mutat...

journal_title：Cancer cytopathology

authors： Dugas SG,Müller DC,Le Magnen C,Federer-Gsponer J,Seifert HH,Ruiz C,Savic Prince S,Vlajnic T,Zellweger T,Mertz KD,Bacon JVW,Wyatt AW,Rentsch CA,Bubendorf L

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Urine cytology results that are suspicious for urothelial carcinoma (UC) are challenging. The objective of this study was to elucidate the clinical significance of such results in patients who have a negative cystoscopy. METHODS:In this prospective study, 83 patients who had urine cytology that was suspicio...

journal_title：Cancer cytopathology

authors： Montalbo R,Izquierdo L,Ingelmo-Torres M,Galve P,Solé M,Franco A,Ribal MJ,Alcaraz A,Mengual L

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Second-opinion diagnosis (SOD) on pathological material is an accepted practice before definitive therapy is considered for referred patients. The thyroid gland is an anatomical site prone to diagnostic disagreement between pathologists. We performed a review of the literature that addressed the role of inte...

journal_title：Cancer cytopathology

authors： Gerhard R,Boerner SL

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Accurate fine-needle aspiration (FNA) diagnosis of metastatic melanoma is of therapeutic and prognostic significance and often requires ancillary studies. To the authors' knowledge, the reliability of immunostaining using a pan-melanoma cocktail, Sry-related HMG-BOX gene 10 (SOX10), and microphthalmia transc...

journal_title：Cancer cytopathology

authors： Clevenger J,Joseph C,Dawlett M,Guo M,Gong Y

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Liquid-based cytology (LBC) is a useful cytopathological method, and LBC lung adenocarcinoma specimens may be used for genetic analysis in the near future. In the current study, the authors determined whether LBC specimens can be used for epidermal growth factor receptor (EGFR) mutation analysis in human lun...

journal_title：Cancer cytopathology

authors： Matsuo Y,Yoshida T,Yamashita K,Satoh Y

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Personalized oncology requires molecular analysis of tumor cells. Several studies have demonstrated that cytological material is suitable for DNA analysis, but to the authors' knowledge there are no systematic studies comparing how the yield and quality of extracted DNA is affected by the various techniques ...

journal_title：Cancer cytopathology

authors： Dejmek A,Zendehrokh N,Tomaszewska M,Edsjö A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Recommendations regarding how many nodules to biopsy with thyroid fine-needle aspiration vary. METHODS:The authors reviewed fine-needle aspiration specimens of 12,763 nodules from 10,506 patients and correlated them with the number of nodules biopsied. RESULTS:Compared with patients in whom only a single n...

journal_title：Cancer cytopathology

authors： Renshaw AA,Gould EW

更新日期：2017-11-01 00:00:00

abstract：:Ocular cytology specimens are small, with limited options for a repeat biopsy. Appropriate handling of these specimens and triaging for ancillary testing can be taxing. In this article, the author reviews a selection of potentially challenging diagnoses and current common practices and methods used in diagnosing ocula...

journal_title：Cancer cytopathology

authors： Laver NMV

更新日期：2020-11-02 00:00:00

abstract：BACKGROUND:BRAF mutations are highly specific for papillary thyroid carcinoma (PTC) and many cytology specimens with BRAF mutations are expected to demonstrate cytologic features typical of PTC. However, indeterminate thyroid cytology cases are inevitable and understanding the significance of the BRAF mutation within t...

journal_title：Cancer cytopathology

authors： Ohori NP,Singhal R,Nikiforova MN,Yip L,Schoedel KE,Coyne C,McCoy KL,LeBeau SO,Hodak SP,Carty SE,Nikiforov YE

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) to identify specific DNA target sequences in the nuclei of nondividing cells of numerous solid neoplasms has contributed to the introduction of molecular cytogenetics as a useful adjunct to cytology, leading recently to the "marriage" of the 2 disciplines. Numerous c...

journal_title：Cancer cytopathology

authors： Caria P,Frau DV,Dettori T,Boi F,Lai ML,Mariotti S,Vanni R

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:The current study was conducted to compare DNA yield, including normalization to nuclear area, DNA amplification functionality, and detection of KRAS mutations between matched fine-needle aspiration (FNA) specimens and pancreatic resections diagnostic of pancreatic ductal adenocarcinoma. METHODS:A retrospec...

journal_title：Cancer cytopathology

authors： Hartley CP,Mahajan AM,Selvaggi SM,Rehrauer WM

更新日期：2017-11-01 00:00:00

abstract：:The practice of cytopathology has dramatically changed due to advances in genomics and information technology. Cytology laboratories have accordingly become increasingly dependent on pathology informatics support to meet the emerging demands of precision medicine. Pathology informatics deals with information technolog...

journal_title：Cancer cytopathology

authors： Hanna MG,Pantanowitz L

更新日期：2017-06-01 00:00:00

abstract：:BACKGROUND.: Pancreatic ductal adenocarcinoma is rarely detected early enough for patients to be cured. The objective of the authors was to develop a monoclonal antibody to distinguish adenocarcinoma and precancerous intraductal papillary mucinous neoplasia (IPMN) from benign epithelium. METHODS.: Mice were immunized ...

journal_title：Cancer cytopathology

authors： Morgan TK,Hardiman K,Corless CL,White SL,Bonnah R,Van de Vrugt H,Sheppard BC,Grompe M,Cosar EF,Streeter PR

更新日期：2013-01-01 00:00:00