Diagnostic value of metabolic phenotypes in malignant pleural effusions: expression of GLUT1 and CAIX by immunocytochemistry.

abstract：BACKGROUND:Fine-needle aspiration (FNA) is widely accepted in the preoperative management of salivary gland lesions. The proposed Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) aims to standardize reporting terminology. Studies regarding the risk of malignancy (ROM) for the proposed categories continu...

journal_title：Cancer cytopathology

authors： Viswanathan K,Sung S,Scognamiglio T,Yang GCH,Siddiqui MT,Rao RA

更新日期：2018-08-01 00:00:00

abstract：:BACKGROUND.: Pancreatic ductal adenocarcinoma is rarely detected early enough for patients to be cured. The objective of the authors was to develop a monoclonal antibody to distinguish adenocarcinoma and precancerous intraductal papillary mucinous neoplasia (IPMN) from benign epithelium. METHODS.: Mice were immunized ...

journal_title：Cancer cytopathology

authors： Morgan TK,Hardiman K,Corless CL,White SL,Bonnah R,Van de Vrugt H,Sheppard BC,Grompe M,Cosar EF,Streeter PR

更新日期：2013-01-01 00:00:00

abstract：:A pediatric cytopathology symposium was held at the recent 20th International Congress of Cytology, which convened in Sydney, Australia, in May 2019. This educational event brought together cytopathologists from different countries and different institutions to discuss some of the practical considerations when applyin...

journal_title：Cancer cytopathology

authors： Monaco SE,Baloch ZW,Rossi ED,Teot LA,Wright C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The workup of a malignant effusion usually requires immunostaining with a panel of markers. Although nuclear Wilms tumor 1 (WT1) expression is widely used to detect tumors of ovarian and mesothelial origin, it is less well known that WT1 is also expressed in the cytoplasm of melanomas and mesenchymal tumors....

journal_title：Cancer cytopathology

authors： Conner JR,Cibas ES,Hornick JL,Qian X

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The separation of benign from malignant mesothelial proliferations on effusion cytology can be difficult. Loss of methylthioadenosine phosphorylase (MTAP) by immunohistochemistry is an established marker of malignancy in mesothelial proliferations, but to the authors' knowledge largely has been applied only ...

journal_title：Cancer cytopathology

authors： Berg KB,Churg AM,Cheung S,Dacic S

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Morphologic and genetic analysis of thyroid nodules may be performed from a single vial. Preanalytic variables that affect nucleic acid extracted from a single vial are evaluated. METHODS:Thyroid fine-needle aspiration (FNA) specimens collected in CytoLyt were evaluated. A ThinPrep slide was prepared. Extra...

journal_title：Cancer cytopathology

authors： Heymann JJ,Yoxtheimer LM,Park HJ,Fernandez EM,Facey KE,Alperstein SA,Tran HV,Baek I,Scognamiglio T,Rennert H,Siddiqui MT,Song W

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Mutations of AT-rich interactive domain 1 (ARID1A) have been associated with a worse outcome after intravesical treatment with bacille Calmette-Guérin in patients with non-muscle-invasive bladder cancer (NMIBC). Loss of ARID1A protein expression in urine cytology may serve as an indication of an ARID1A mutat...

journal_title：Cancer cytopathology

authors： Dugas SG,Müller DC,Le Magnen C,Federer-Gsponer J,Seifert HH,Ruiz C,Savic Prince S,Vlajnic T,Zellweger T,Mertz KD,Bacon JVW,Wyatt AW,Rentsch CA,Bubendorf L

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Urine cytology has been used for screening of bladder cancer but has been limited by its low sensitivity. UroVysion is a multiprobe fluorescence in situ hybridization (FISH) assay that detects common chromosome abnormalities in bladder cancers. For this study, the authors evaluated the effectiveness of multi...

journal_title：Cancer cytopathology

authors： Dimashkieh H,Wolff DJ,Smith TM,Houser PM,Nietert PJ,Yang J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Accurate fine-needle aspiration (FNA) diagnosis of metastatic melanoma is of therapeutic and prognostic significance and often requires ancillary studies. To the authors' knowledge, the reliability of immunostaining using a pan-melanoma cocktail, Sry-related HMG-BOX gene 10 (SOX10), and microphthalmia transc...

journal_title：Cancer cytopathology

authors： Clevenger J,Joseph C,Dawlett M,Guo M,Gong Y

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) is routinely used to help clarify atypical urinary cytology. However, to the authors' knowledge, little is known regarding the frequency of chromosomal aberrations in non-neoplastic conditions that could potentially lead to false-positive FISH results. The objective ...

journal_title：Cancer cytopathology

authors： Tapia C,Glatz K,Obermann EC,Grilli B,Barascud A,Herzog M,Schönegg R,Savic S,Bubendorf L

更新日期：2011-12-25 00:00:00

abstract：BACKGROUND:Allogenic hematopoietic stem cell transplantation (allo-HSCT) is a common procedure in hematological disorders and is preceded by a conditioning regimen that usually includes busulfan. The immunosuppression caused by the conditioning regimen and graft-versus-host disease prophylaxis is associated with human ...

journal_title：Cancer cytopathology

authors： Saco A,Alòs S,Esteve R,Suárez-Lledó M,Martínez C,Perez FM,Vega N,Martí C,Torne A,Ordi J,Del Pino M

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Undifferentiated carcinoma (UC) is a rare, aggressive subtype of endometrial carcinoma. Dedifferentiated carcinomas (DCs) are UCs associated with a component of well differentiated endometrioid carcinoma. The authors sought to describe the morphologic features of UCs and DCs in cytologic specimens. METHODS:...

journal_title：Cancer cytopathology

authors： Akbari AH,Wang L,Soslow RA,Murali R

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The aim of this study was to validate clinical utilization of routinely prepared cytology specimens for molecular testing to detect EGFR or KRAS mutations in lung cancer. METHODS:From September 2009 to April 2010, the authors collected 209 cytology specimens from patients with lung cancer at the MD Anderson...

journal_title：Cancer cytopathology

authors： Billah S,Stewart J,Staerkel G,Chen S,Gong Y,Guo M

更新日期：2011-04-25 00:00:00

abstract：BACKGROUND:The diagnosis of breast lesions is usually confirmed by fine-needle aspiration cytology (FNAC) or histological biopsy. Although there is increasing literature regarding the advantages and limitations of both modalities, there is no literature regarding the accuracy of these modalities for diagnosing breast l...

journal_title：Cancer cytopathology

authors： Georgieva RD,Obdeijn IM,Jager A,Hooning MJ,Tilanus-Linthorst MM,van Deurzen CH

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The Papanicolaou Society of Cytopathology has recently published a new proposal for pancreaticobiliary cytology terminology. For the current study, the authors applied this new classification for pancreaticobiliary cytology to a set of previously diagnosed endoscopic ultrasound (EUS)-guided fine-needle aspir...

journal_title：Cancer cytopathology

authors： Saieg MA,Munson V,Colletti S,Nassar A

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Carbonic anhydrase IX (CAIX) is a hallmark of metabolic change in cancer cells. The aim was to evaluate the utility of CAIX expression for the detection of malignant pleural effusions by enzyme-linked immunosorbent assay (ELISA) and immunocytochemistry. METHODS:A total of 97 pleural effusions including 54 b...

journal_title：Cancer cytopathology

authors： Liao ND,Lee WY

更新日期：2012-08-25 00:00:00

abstract：BACKGROUND:Liquid-based cytology (LBC) is a useful cytopathological method, and LBC lung adenocarcinoma specimens may be used for genetic analysis in the near future. In the current study, the authors determined whether LBC specimens can be used for epidermal growth factor receptor (EGFR) mutation analysis in human lun...

journal_title：Cancer cytopathology

authors： Matsuo Y,Yoshida T,Yamashita K,Satoh Y

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Atypical glandular cells (AGC) is a very important diagnosis in gynecological cytology. In the current study, the authors investigated the usefulness of Cellient cell blocks (CB) for characterizing AGC on Papanicolaou (Pap) tests. METHODS:A total of 148 patients with an AGC diagnosis based on Pap tests by c...

journal_title：Cancer cytopathology

authors： Xing W,Hou AY,Fischer A,Owens CL,Jiang Z

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess how atypical diagnostic category (ADC) is followed up, its outcomes, and the predictors that are associated with subsequent diagnosis of neoplasm/malignancy. METHODS:We reviewed pancreatic endoscopic ultrasound fine-needle aspiration (EUS-FNA) with ADC and compared ...

journal_title：Cancer cytopathology

authors： Alston E,Bae S,Eltoum IA

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Limited studies have examined the impact of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) and specifically the category of atypia or follicular lesion of undetermined significance (AUS/FLUS). We studied their effects on reporting rates, subsequent management, and surgical outcome over a 10-...

journal_title：Cancer cytopathology

authors： Sullivan PS,Hirschowitz SL,Fung PC,Apple SK

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:BRAF mutations are highly specific for papillary thyroid carcinoma (PTC) and many cytology specimens with BRAF mutations are expected to demonstrate cytologic features typical of PTC. However, indeterminate thyroid cytology cases are inevitable and understanding the significance of the BRAF mutation within t...

journal_title：Cancer cytopathology

authors： Ohori NP,Singhal R,Nikiforova MN,Yip L,Schoedel KE,Coyne C,McCoy KL,LeBeau SO,Hodak SP,Carty SE,Nikiforov YE

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the diagnostic accuracy of the Bladder EpiCheck test in the follow-up of patients with non-muscle-invasive bladder cancer (NMIBC) and to compare it with the accuracy of urinary cytology, cystoscopy, and/or histology. METHODS:In total, 243 patients were enrolled in...

journal_title：Cancer cytopathology

authors： Trenti E,D'Elia C,Mian C,Schwienbacher C,Hanspeter E,Pycha A,Kafka M,Degener S,Danuser H,Roth S,Pycha A

更新日期：2019-07-01 00:00:00

abstract：:The 8th Annual National Molecular Cytopathology Meeting, held in Naples, Italy, on December 2 to 3, 2019, addressed updates in diagnostic cytopathology and molecular classifications and specifically focused on lung cancer biomarker testing in cytology samples. Lung cancer continues to be the most commonly diagnosed no...

journal_title：Cancer cytopathology

authors： Rossi ED,Wiles A,Vecchione A

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The accumulation of cyclin-dependent kinase inhibitor 2A (p16ink4a ) protein in a cell is associated with neoplastic progression in precancerous cervical lesions. Dual staining for p16ink4a and Ki-67 has been proposed as a triage test in cervical cancer screening for women who test positive for human papillo...

journal_title：Cancer cytopathology

authors： Benevolo M,Allia E,Gustinucci D,Rollo F,Bulletti S,Cesarini E,Passamonti B,Giovagnoli MR,Carico E,Carozzi FM,Mongia A,Fantacci G,Confortini M,Rubino T,Fodero C,Prandi S,Marchi N,Farruggio A,Coccia A,Macrì L,Ghirin

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Although thyroid fine-needle aspiration (TFNA) is an excellent test in evaluating thyroid nodules, there are occasionally false negatives (FN). The clinical impact and pathologic features of FN TFNA is understudied in the peer-reviewed literature. METHODS:A cohort of patients with thyroid cancer was separat...

journal_title：Cancer cytopathology

authors： Jean-Gilles J,Fischer AH,Luu MH,Owens CL

更新日期：2012-10-25 00:00:00

abstract：BACKGROUND:Fluorescent in situ hybridization (FISH) analysis of urine samples has proven to be a valuable adjunctive test to urine cytology for both diagnosis and monitoring recurrence of urothelial carcinoma. Automated FISH analysis has the potential to improve laboratory efficiency and to reduce interobserver and int...

journal_title：Cancer cytopathology

authors： Marganski WA,El-Sirgany Costa V,Kilpatrick MW,Tafas T,Yim J,Matthews M

更新日期：2011-08-25 00:00:00

abstract：BACKGROUND:New developments in the treatment of lung cancer have necessitated the further histologic and cytologic subtyping of nonsmall cell lung carcinomas. Thyroid transcription factor-1 (TTF-1) long has served as the predominant marker for demonstrating lung origin. However, it is also expressed in a variety of oth...

journal_title：Cancer cytopathology

authors： Stoll LM,Johnson MW,Gabrielson E,Askin F,Clark DP,Li QK

更新日期：2010-12-25 00:00:00

abstract：BACKGROUND:The use of topically applied hemostatic substances during surgery has become a common practice. In some cases, the material is not absorbed or induces a granulomatous reaction resulting in a pseudotumoral lesion. With imaging studies, it is not possible to differentiate this from a tumor recurrence or absces...

journal_title：Cancer cytopathology

authors： Hernández-Bonilla S,Rodríguez-García AM,Jiménez-Heffernan JA,Muñoz-Hernández P,Palacios-Lázaro E,López-Ferrer P,González-Peramato P,Vicandi B

更新日期：2019-12-01 00:00:00

abstract：:Follicular cell-derived carcinomas of the thyroid gland comprise a heterogeneous group of malignant neoplasms of the thyroid gland with varied histologic appearance and molecular profiles. In most patients, these tumors represent relatively indolent neoplasms; however, certain subtypes/variants behave in an aggressive...

journal_title：Cancer cytopathology

authors： Lastra RR,LiVolsi VA,Baloch ZW

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration of the thyroid is a common procedure, with an established role in reducing unnecessary thyroid surgery and identifying neoplasms and malignancies. METHODS:The study evaluated 1558 responses in the American Society for Clinical Pathology (ASCP) Non-GYN Assessment program of aspirates o...

journal_title：Cancer cytopathology

authors： Eilers SG,LaPolice P,Mukunyadzi P,Kapur U,Wendel Spiczka A,Shah A,Saleh H,Adeniran A,Nunez A,Balachandran I,Clark JJ,Lemon L

更新日期：2014-10-01 00:00:00