Abstract:
OBJECTIVE:Studies of the relationship between obesity and chronic kidney disease (CKD) in nationally representative population samples are limited. Our study aimed to determine if overweight and obesity were independently associated with the risk for CKD in the 2010 Health Survey for England (HSE). DESIGN:The HSE is an annually conducted cross-sectional study. In 2010 serum creatinine was included to determine the incidence of CKD in the population. CKD was defined as estimated glomerular filtration rate (eGFR) <60 ml/min per 1.73 m2 using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula. Multivariable logistic regression models were developed to calculate odds ratios and 95% confidence intervals for CKD risk by BMI (reference category: BMI=18.5-24.9 kg/m2) and adjusted for age, gender, ethnicity, smoking, diabetes and hypertension. SETTING:A random sample of nationally representative households in England. SUBJECTS:Adults (n 3463) with calculable eGFR and BMI were included. RESULTS:The prevalence of CKD was 5.9%. The risk of CKD was over 2.5 times higher in obese participants compared with normal-weight participants in the fully adjusted model (BMI=30.0-39.9 kg/m2: adjusted OR=2.78 (95% CI 1.75, 4.43); BMI ≥ 40.0 kg/m2: adjusted OR=2.68 (95% CI 1.05, 6.85)). CONCLUSIONS:Obesity is associated with an increased risk of CKD in a national sample of the UK population, even after adjustment for known CKD risk factors, which may have implications for CKD screening and future national health service planning and delivery.
journal_name
Public Health Nutrjournal_title
Public health nutritionauthors
MacLaughlin HL,Hall WL,Sanders TA,Macdougall ICdoi
10.1017/S1368980015000488subject
Has Abstractpub_date
2015-12-01 00:00:00pages
3349-54issue
18eissn
1368-9800issn
1475-2727pii
S1368980015000488journal_volume
18pub_type
杂志文章abstract:OBJECTIVE:To describe the knowledge, attitudes and practices of type 2 diabetics in Yakeshi City and to assess the effect of implementation of nutritional and eating education in enhancing knowledge and practices regarding a healthy diet. DESIGN:A questionnaire-based survey was conducted with 162 diabetics to determin...
journal_title:Public health nutrition
pub_type: 杂志文章,多中心研究,随机对照试验
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pub_type: 杂志文章
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更新日期:2016-06-01 00:00:00
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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更新日期:2020-09-16 00:00:00
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