Intake of B vitamins in childhood and adult life in relation to psychological distress among women in a British birth cohort.

Abstract:

BACKGROUND:Lower levels of B vitamins (particularly folate, vitamin B12 and vitamin B6) may be associated with psychological distress. Little is known about the impact of childhood nutrition on psychological distress in adult life. OBJECTIVE:We investigated whether prospectively measured childhood and adult dietary intakes of thiamin, riboflavin, niacin, folate, vitamin B6 and vitamin B12 were related to the psychological distress of women in mid-age, taking into account socio-economic, behavioural and lifestyle factors. DESIGN:Prospective data were collected from a cohort of 636 British women followed up since their birth in 1946. Participants completed a 28-item, scaled version of the General Health Questionnaire (GHQ-28) to measure psychological distress at age 53 years. Dietary intakes in childhood (at age four) were determined by 24h recall and in adulthood (at age 36, 43 and 53 years) by a 5d food record. RESULTS:Low dietary vitamin B12 intake at age 53 was associated with higher psychological distress at that age. Women in the lowest third of vitamin B12 intake in adulthood had a higher GHQ-28 score compared with those in the highest third (percentage change, adjusted regression coefficient, 21 (95% CI 3, 39)). There were no other significant associations between dietary B vitamin intake in childhood or adulthood and psychological distress in the cohort. CONCLUSIONS:Overall, there is evidence that intake of vitamin B12 at age 53 is related to adult psychological distress but there is no evidence for the effects of other adult B vitamin intakes or childhood intakes on psychological distress.

journal_name

Public Health Nutr

journal_title

Public health nutrition

authors

Mishra GD,McNaughton SA,O'Connell MA,Prynne CJ,Kuh D

doi

10.1017/S1368980008002413

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

166-74

issue

2

eissn

1368-9800

issn

1475-2727

pii

S1368980008002413

journal_volume

12

pub_type

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