Abstract:
OBJECTIVE:To evaluate the prevalence of vitamin D deficiency and insufficiency, as well as their association with Hb and elevated blood lead levels (BLL) in children in China. DESIGN:A cross-sectional and 1-year retrospective study. SETTING:Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, China. SUBJECTS:Children aged from 6 months to 14 years living in south-west China who were taken to physical examinations (January-December 2011). RESULTS:Of 1218 children included in the study, 25-hydroxyvitamin D (25(OH)D) concentration (mean 33.18 (sd 16.48) ng/ml) was deficient in 21.6% and insufficient in 27.4%, which were higher than the prevalence of both anaemia at 8.5% and elevated BLL (Pb ≥ 10 μg/dl) at 1.8%, but lower than mildly elevated BLL prevalence (5 μg/dl ≤ Pb < 10 μg/dl) at 56.9%. There was a negative correlation between 25(OH)D concentration and BLL (r = -0.216, P < 0.001) while no significant relationship was found between 25(OH)D concentration and Hb (r = -0.012, P > 0.05). After multivariable adjustment, the significant predictors of 25(OH)D deficiency and insufficiency were increasing child age especially between 8 and 14 years (OR = 18.29; 95% CI 10.14, 32.99; P < 0.001) and BLL (OR = 1.01; 95% CI 1.00, 1.02; P = 0.045). CONCLUSIONS:The prevalence of 25(OH)D deficiency and insufficiency was much higher than that of anaemia or elevated BLL in south-west China, and associated with increasing age and BLL.
journal_name
Public Health Nutrjournal_title
Public health nutritionauthors
Chang L,Liu X,Shi H,Dai W,Wang H,Jiang Ydoi
10.1017/S1368980013001675subject
Has Abstractpub_date
2014-04-01 00:00:00pages
827-32issue
4eissn
1368-9800issn
1475-2727pii
S1368980013001675journal_volume
17pub_type
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journal_title:Public health nutrition
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journal_title:Public health nutrition
pub_type: 杂志文章,评审
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