Abstract:
OBJECTIVE:Hepatic impairment resulting from the use of conventional drugs is widely acknowledged, but there is less awareness of the potential hepatotoxicity of herbal preparations and other botanicals, many of which are believed to be harmless and are commonly used for self-medication without supervision. The aim of this paper is to examine the evidence for hepatotoxicity of botanicals and draw conclusions regarding their pathology, safety and applications. DESIGN:Current literature on the hepatotoxicity of herbal drugs and other botanicals is reviewed. The aetiology, clinical picture and treatment of mushroom (Amanita) poisoning are described. RESULTS:Hepatotoxic effects have been reported for some Chinese herbal medicines (such as Jin Bu Huan, Ma-Huang and Sho-saiko-to), pyrrolizidine alkaloid-containing plants, germander (Teucrium chamaedrys), chaparral (Larrea tridentata), Atractylis gummifera, Callilepsis laureola, and others. The frequency with which botanicals cause hepatic damage is unclear. There is a lack of controlled treatment trials and the few studies published to date do not clarify the incidence of adverse effects. Many plant products do not seem to lead to toxic effects in everyone taking them, and they commonly lack a strict dose-dependency. For some products, such as Sho-saiko-to, the picture is confused further by demonstrations of hepatoprotective properties for some components. Mushroom poisoning is mostly due to the accidental consumption of Amanita species. Treatment with silymarin, thioctic acid, penicillin and liver transplantation have been shown to be effective but require early diagnosis. CONCLUSIONS:Severe liver injury, including acute and chronic abnormalities and even cirrhotic transformation and liver failure, has been described after the ingestion of a wide range of herbal products and other botanical ingredients, such as mushrooms. It is concluded that in certain situations herbal products may be just as harmful as conventional drugs.
journal_name
Public Health Nutrjournal_title
Public health nutritionauthors
Stickel F,Egerer G,Seitz HKdoi
10.1017/s1368980000000161subject
Has Abstractpub_date
2000-06-01 00:00:00pages
113-24issue
2eissn
1368-9800issn
1475-2727pii
S1368980000000161journal_volume
3pub_type
杂志文章,评审abstract:OBJECTIVE:Perceptions of social-contextual food environments and associated factors that influence food purchases are understudied in American Indian (AI) communities. The purpose of the present study was to: (i) understand the perceived local food environment; (ii) investigate social-contextual factors that influence ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980019001095
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:Relationships among race/ethnicity, individual socio-economic status (SES), neighbourhood SES and acculturation are complex. We sought to answer whether: (i) race/ethnicity, individual SES and neighbourhood SES have independent effects on women's fruit and vegetable consumption (FVC); (ii) SES modifies the ef...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980015003225
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:To date, no data exist on the agreement of food choice measured using an online tool with subsequent actual consumption. This needs to be shown before food choice, measured by means of an online tool, is used as a dependent variable to examine intake in the general population. DESIGN:A 'web-buffet' was devel...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980014002456
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Low- and middle-income countries are experiencing rises in the prevalence of adult obesity. Whether these increases disproportionately affect vulnerable subpopulations is unclear because most previous investigations were not nationally representative, were limited to women, or relied on self-reported anthropo...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980013003418
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:The relation between several measures of body iron and atherosclerotic disease, particularly acute myocardial infarction (AMI), is debated. This is of specific interest since iron is frequently included in supplementation and fortification of foods. We assessed the relation between dietary iron intake and the...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1079/phn2005869
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility and efficacy of in-restaurant interventions aiming to promote healthy choices via fundraising incentives benefiting school wellness programmes and point-of-purchase nutrition promotion. DESIGN:Twelve schools were randomly assigned to one of the two intervention periods: Fundraising ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980019004609
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:Diet and nutrition in childhood has been associated with the risk of chronic disease later in life. The aim of this review was to identify key characteristics of successful experiential nutrition interventions aimed to change nutrition-related cognitive and behavioural outcomes in primary schoolchildren. DES...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980020004024
更新日期:2020-10-14 00:00:00
abstract:OBJECTIVE:To examine associations of various psychosocial factors with fruit and vegetable intake in African-American adults. METHODS:A cross-sectional survey of a population-based sample of 658 African-Americans, aged 18-70 years, in North Carolina. Information was collected on diet-related psychosocial (predisposing...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980007662284
更新日期:2007-07-01 00:00:00
abstract:OBJECTIVE:The current study characterizes associations between physical and social contexts of self-reported primary episodes of eating/drinking and sociodemographic and obesity-related variables in US adults. DESIGN:Multinomial logistic regression was used to analyse a nationally representative sample of adults from ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980013003315
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:The current mixed-methods study explored qualitative accounts of prior childhood experiences and current contextual factors around family meals across three quantitatively informed categories of family meal frequency patterns from adolescence to parenthood: (i) 'maintainers' of family meals across generations...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980018003920
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVE:To pilot-test a brief written prescription recommending lifestyle changes delivered by general practitioners (GPs) to their patients. DESIGN:The Active Nutrition Script (ANS) included five nutrition messages and personalised exercise advice for a healthy lifestyle and/or the prevention of weight gain. GPs we...
journal_title:Public health nutrition
pub_type: 临床试验,杂志文章
doi:10.1017/s1368980006009803
更新日期:2006-12-01 00:00:00
abstract:OBJECTIVE:The risk factors for fractures are incompletely understood. An outstanding question concerns the optimal amount of dietary calcium needed to minimise the risk of fracture. DESIGN:We examined the associations of dietary calcium and other nutrients with self-reported fracture risk in a prospective cohort study...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980007696402
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVE:To describe the development and application of the School Food Environment Assessment Tools and a novel scoring system to assess the integration of healthy and environmentally sustainable food initiatives in elementary and secondary schools. DESIGN:The cross-sectional study included direct observations of ph...
journal_title:Public health nutrition
pub_type: 杂志文章,评审
doi:10.1017/S1368980015000531
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:To investigate trends in child anthropometry in Senegal between 1990 and 2015 and relate them with potential causes. Several hypotheses were tested: changes in health status, income, diet and socio-economic status. DESIGN:Statistical analysis of trends in anthropometric data: height, weight, BMI and associat...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980019003598
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Stunting (height-for-age < -2 sd) is one of the forms of undernutrition and is frequent among children of low- and middle-income countries. But stunting perse is not a synonym of undernutrition. We investigated association between body height and indicators of energetic undernutrition at three critical thresh...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980020003067
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Obesity and hyperglycaemia contribute to the atherosclerotic process in part through oxidative modifications to lipoprotein particles. The present study aimed to evaluate the effects of a lifestyle intervention on markers of oxidized lipoproteins in obese Latino adolescents with prediabetes. DESIGN:Pre-post ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980018003476
更新日期:2018-12-27 00:00:00
abstract:OBJECTIVE:To describe the diet costs of adults in the National Diet and Nutrition Study (NDNS) and explore patterns in costs according to sociodemographic indicators. DESIGN:Cross-sectional diet diary information was matched to a database of food prices to assign a cost to each food or non-alcoholic beverage consumed....
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980013002905
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To describe dietary habits and extent of overweight and obesity among Cree youth. DESIGN:Dietary intake and habits were assessed by a 24 h recall and FFQ as part of a cross-sectional survey. SETTING:Three Cree communities in northern Québec, Canada. SUBJECTS:A total of 125 youth aged 9-18 years. RESULTS:O...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980010000406
更新日期:2010-11-01 00:00:00
abstract:OBJECTIVE:To examine the effects of lunches with different dietary energy densities on food preferences between genders. DESIGN:Randomized crossover study. Participants were administered the following packed test meals once weekly on a specified day during six sessions: control (150 g of rice with a sautéed beef entré...
journal_title:Public health nutrition
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/S1368980014001426
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:Much is known about national trends in child undernutrition, but there is little information on how socio-economic inequalities are evolving over time. We aimed to assess socio-economic inequalities in stunting prevalence over time. DESIGN:We selected nationally representative surveys carried out since the m...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980014002924
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Many public health campaigns encourage increased fibre consumption, but short-term studies suggest that various components of dietary fibre inhibit the absorption of certain micronutrients including carotenoids. These do not take into account long-term adaptation to nutrient intake levels. We aimed to investi...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1079/PHN2003571
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:To develop and apply a socio-ecological model (SEM) for healthy eating in school students, to better understand the association between factors at different levels of the SEM and pupils' dietary choices. DESIGN:Student-level data, collected through anonymised questionnaires, included reported dietary choices...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980011002655
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:Drinking water instead of beverages with added sugar can help prevent obesity and cavities and promote overall health. Children spend much of their day in school, where they have variable access to drinking water. In 2010, federal and state law required California public schools to provide free potable water ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980019003975
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:This paper investigates the roles of the individual stakeholders involved in the development of functional foods and the implications of their actions for public perception of this new food concept. RESULTS:At a time when consumer awareness of the link between diet and health is strong, a new food concept in...
journal_title:Public health nutrition
pub_type: 杂志文章,评审
doi:10.1079/phn2001268
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVE:To describe fruit and vegetable (FV) feeding practices at 6 months, and to examine whether these practices predict children's FV intake at 7 years of age. DESIGN:A prospective, longitudinal design was adopted. The mothers completed self-reported questionnaires at 6 months and 7 years postpartum, containing q...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980010000790
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:The insulin-like growth factor (IGF) system has been implicated in the aetiopathogenesis of cancer, cardiovascular disease and diabetes. Since dietary factors and ethnicity are considered contributory to the development of these diseases, we examined the IGF system in relation to nutritional intake by ethnic ...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1079/PHN2002414
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:To assess sociodemographic correlates of micronutrient intakes from food and dietary supplements in an urban, ethnically diverse sample of pregnant women in the USA. DESIGN:Cross-sectional analyses of data collected using a validated semi-quantitative FFQ. Associations between racial, ethnic and sociodemogra...
journal_title:Public health nutrition
pub_type: 杂志文章,多中心研究
doi:10.1017/S1368980013003224
更新日期:2014-09-01 00:00:00
abstract:OBJECTIVE:To determine the association of gestational weight gain (GWG) or pre-pregnancy BMI with postpartum weight retention (PPWR). DESIGN:Meta-analysis. SETTING:PubMed, Cochrane Controlled Trials Register, EMBASE, Science Citation Index Expanded, Current Contents Connects and Biosis Previews were used to search ar...
journal_title:Public health nutrition
pub_type: 杂志文章,meta分析,评审
doi:10.1017/S1368980014002523
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:Dietary intake is a leading risk factor for hypertension. We aimed to assess longitudinal associations between overall dietary patterns and incident hypertension among adults in Thailand. DESIGN:Prospective large Thai Cohort Study (TCS) conducted nationwide from 2005 to 2013. Dietary patterns were identified...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980018002203
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The incidence of osteoporosis increases with age and is most frequently observed in postmenopausal women. The objective of the present population-based cohort study was to assess the influence of Ca intake from dairy sources on hip bone mineral density and hip fracture incidence in a group of Polish women ove...
journal_title:Public health nutrition
pub_type: 杂志文章
doi:10.1017/S1368980012005307
更新日期:2014-02-01 00:00:00