Full genome sequence analysis of a wild, non-MLV-related type 2 Hungarian PRRSV variant isolated in Europe.

abstract：:Since 2002 there has been a rise in arthrogryposis/hydranencephaly (AGH) incidence in Israel, caused by Akabane (AKA) and, possibly, Aino viruses. To test the ability to control the disease, three siRNA genes targeted to the S genome segment were designed and prepared in the form of siRNA cassettes. For the design all...

journal_title：Virus research

authors： Levin A,Kutznetova L,Kahana R,Rubinstein-Guini M,Stram Y

更新日期：2006-09-01 00:00:00

abstract：:VP28 and VP24 are two major envelope proteins of white spot syndrome virus (WSSV). The direct interaction between VP28 and VP24 has been described in previous studies. In this study, we confirmed this interaction and mapped the interaction domains of VP28 and VP24 by constructing a series of deletion mutants. By co-im...

journal_title：Virus research

authors： Li Z,Chen W,Xu L,Li F,Yang F

更新日期：2015-03-16 00:00:00

abstract：:A recombinant baculovirus, the genome of which contains DNA encoding Marek's disease virus serotype 1 (MDV1) homolog of glycoprotein D (gD) of herpes simplex virus under the polyhedrin promoter was constructed and designated rAcMDV1gD. Five monoclonal antibodies (MAbs) which recognize the MDV1 homolog of gD (MDV1 gD) ...

journal_title：Virus research

authors： Ono M,Jang HK,Maeda K,Kawaguchi Y,Tohya Y,Niikura M,Mikami T

更新日期：1995-10-01 00:00:00

abstract：:The epitopes of six monoclonal antibodies generated against type A12 foot-and-mouth disease virus (FMDV) VP1 or its largest cyanogen bromide fragment (13 kd) were characterized. Five of these monoclonal antibodies neutralized viral infectivity. Solid-phase and competitive antigen binding assays using virion-derived an...

journal_title：Virus research

authors： Robertson BH,Morgan DO,Moore DM

更新日期：1984-09-01 00:00:00

abstract：:The complete cDNA sequence corresponding to the genomic RNA of a South American strain of potato virus X (PVXc) is reported. The sequence (6432 nucleotides) contains five open reading frames coding for polypeptides with molecular weights of 165.3, 24.3, 12.3, 7.6 and 25.0 and displays an overall homology of 77.4% with...

journal_title：Virus research

authors： Orman BE,Celnik RM,Mandel AM,Torres HN,Mentaberry AN

更新日期：1990-07-01 00:00:00

abstract：:To gain more insights into the epidemiology of hantaviruses in China, the hantaviral S, M and L segment sequences were recovered from two Microtus fortis captured in Shenyang and four M. fortis trapped in Yuanjiang in China. Genetic analysis revealed that Shenyang sequences are closely related to the sequences of Fuso...

journal_title：Virus research

authors： Zou Y,Xiao QY,Dong X,Lv W,Zhang SP,Li MH,Plyusnin A,Zhang YZ

更新日期：2008-10-01 00:00:00

abstract：:The release of retrovirus particles from the infected cell is greatly stimulated by short motifs, known as "late" or "L" domains, present within the Gag precursor protein. Three distinct classes of L domains have been identified; these bear the core sequence: Pro-Thr/Ser-Ala-Pro [P(T/S)AP], Pro-Pro-x-Tyr (PPxY), or Ty...

journal_title：Virus research

authors： Demirov DG,Freed EO

更新日期：2004-12-01 00:00:00

abstract：:In this study we demonstrated that Macrobrachium rosenbergii nodavirus (MrNV) was able to internalize and replicate in Sf9 insect cells, with levels of infection altered by substances affecting the caveolin-(CAV) mediated endocytosis pathway. The use of Sf9 cells for efficient MrNV replication and propagation was demo...

journal_title：Virus research

authors： Somrit M,Watthammawut A,Chotwiwatthanakun C,Weerachatyanukul W

更新日期：2016-09-02 00:00:00

abstract：:The attenuated equine infectious anemia virus (EIAV) vaccine was the first attenuated lentivirus vaccine to be used in a large-scale application and has been used to successfully control the spread of equine infectious anemia (EIA) in China. To better understand the potential role of cytokines in the pathogenesis of E...

journal_title：Virus research

authors： Lin YZ,Cao XZ,Li L,Li L,Jiang CG,Wang XF,Ma J,Zhou JH

更新日期：2011-09-01 00:00:00

abstract：:The influenza A virus RNA-dependent RNA polymerase catalyzes several reactions in transcription and replication of the genome RNA. The first step in viral mRNA synthesis is the recognition of the 5' end cap structure of host cell hnRNA and the cleavage of the RNA substrate between 10 and 14 nucleotides from the 5' end...

journal_title：Virus research

authors： Shi L,Galarza JM,Summers DF

更新日期：1996-06-01 00:00:00

abstract：:As master transcription factors for lipogenesis, sterol regulatory element-binding protein-1 (SREBP-1) has two isoforms, SREBP-1a and SREBP-1c. Hepatitis B virus X (HBx) can up-regulate the transcription of both SREBP-1a and SREBP-1c. HBx is a small protein consisting of 154 amino acids. Truncated forms of HBx, often ...

journal_title：Virus research

authors： Wu Q,Liu Q

更新日期：2015-12-02 00:00:00

abstract：:A sero-epidemiologic survey of 74 IVDUs and 86 age-matched controls was performed to investigate the prevalence, clinical significance, and genetic distribution of GB virus C (GBV-C)/hepatitis G virus (HGV) infection among intravenous drug users (IVDUs) in Japan. GBV-C/HGV RNA was detected by reverse transcriptase-hem...

journal_title：Virus research

authors： Noguchi S,Sata M,Suzuki H,Ohba K,Mizokami M,Tanikawa K

更新日期：1997-06-01 00:00:00

abstract：:Equine rhinitis A virus (ERAV) is a picornavirus which causes an acute respiratory infection in horses worldwide, and virus neutralization (VN) has been the standard method for the detection of ERAV antibody in horse serum. Previous studies have identified recombinant virion protein VP1 (rVP1) purified under native co...

journal_title：Virus research

authors： Kriegshäuser G,Kuechler E,Skern T

更新日期：2009-07-01 00:00:00

abstract：:Dengue (Den) viruses cause apoptosis in mammalian cells, but usually result in high progeny yields without evident damage in mosquito cells. By using subtractive hybridization, 13 potentially virus-induced genes were selected in Den-2 virus-infected Aedes albopictus C6/36 cells. Based on semi-quantitative and real-tim...

journal_title：Virus research

authors： Lin CC,Yang CF,Tu CH,Huang CG,Shih YT,Chuang CK,Chen WJ

更新日期：2007-03-01 00:00:00

abstract：:We have found that an HIV-1 accessory gene product Vpr enhanced HIV-1 reproduction in U1 cells chiefly by the induction of TNF, a proinflammatory cytokine, which was also known to be an activator of HIV-1 reproduction. We have generated the functional HIV-1 accessory gene product Vpr in bacterial cells. Vpr was genera...

journal_title：Virus research

authors： Nakamura T,Suzuki H,Okamoto T,Kotani S,Atsuji Y,Tanaka T,Ito Y

更新日期：2002-12-01 00:00:00

abstract：:The cDNA of the nucleocapsid (core) protein of classical swine fever virus (CSFV) was generated by reverse transcription-polymerase chain reaction (RT-PCR) and cloned into a eukaryotic expression vector. The effect of the recombinant core protein on the transcriptional regulation of cellular as well as viral promoters...

journal_title：Virus research

authors： Liu JJ,Wong ML,Chang TJ

更新日期：1998-01-01 00:00:00

abstract：:Reports of human infections with highly pathogenic H5N1 avian influenza viruses in many countries in Asia and Africa with varying case fatality rates highlight the pandemic potential of these viruses. In order to contain a rapidly spreading influenza virus in a pandemic scenario, a vaccine which can induce rapid and r...

journal_title：Virus research

authors： Vemula SV,Amen O,Katz JM,Donis R,Sambhara S,Mittal SK

更新日期：2013-12-26 00:00:00

abstract：:The immunopathogenesis of severe hand, foot and mouth disease (HFMD) remains elusive. This study revealed that enterovirus 71 (EV71) epitope-specific CD4+ T cell responses of HFMD patients were skewed toward a Th2 cytokine profile. Patients that demonstrated higher levels of IL-4 expression in their CD4 T cells follow...

journal_title：Virus research

authors： Wei R,Xu L,Zhang N,Zhu K,Yang J,Yang C,Deng C,Zhu Z,De Groot AS,Altmeyer R,Zeng M,Leng Q

更新日期：2013-10-01 00:00:00

abstract：:Hepatitis B virus (HBV) surface antigen (HBsAg), which is encoded by the HBV S gene, is conventionally classified into 4 serological subtypes, adw, adr, ayw and ayr. To determine the relationship between the HBsAg seroreactivity and the nucleotide sequence diversity of the HBV S gene, the nucleotide sequences of S gen...

journal_title：Virus research

authors： Ohba K,Mizokami M,Ohno T,Suzuki K,Orito E,Lau JY,Ina Y,Ikeo K,Gojobori T

更新日期：1995-11-01 00:00:00

abstract：:The complete nucleotide sequence (2209 nucleotides) of the RNA 3 of the cucumber mosaic virus strain Trk7 was determined. Trk7-CMV possesses two open reading frames which encode the 3a protein (279 amino acids) and the coat protein (218 amino acids). Sequence analysis proved the earlier biological and serological clas...

journal_title：Virus research

authors： Salánki K,Thole V,Balázs E,Burgyán J

更新日期：1994-03-01 00:00:00

abstract：:Single-cell sequencing (SCS) has emerged as a valuable tool to study cellular heterogeneity in diverse fields, including virology. By studying the viral and cellular genome and/or transcriptome, the dynamics of viral infection can be investigated at single cell level. Most studies have explored the impact of cell-to-c...

journal_title：Virus research

authors： Rato S,Golumbeanu M,Telenti A,Ciuffi A

更新日期：2017-07-15 00:00:00

abstract：:Zika virus is an emergent arbovirus that has caused a public health emergency in South America. Zika virus infection is known to cause microcephaly and other congenital defects and Guillain-Barré syndrome. Unfortunately no direct antiviral treatments are available at present. IFN-stimulated gene 15 (ISG15) is one of t...

journal_title：Virus research

authors： Wang Y,Ren K,Li S,Yang C,Chen L

更新日期：2020-10-02 00:00:00

abstract：:A comprehensive phylogenetic study based on the hemagglutinin (H) protein of all known African measles virus (MV) isolates is presented. The study includes 64 new H gene sequences from Ghana. Nigeria and South Africa as well as viruses from Zambia and The Gambia for which only incomplete sequencing data were available...

journal_title：Virus research

authors： Truong AT,Kreis S,Ammerlaan W,Hartter HK,Adu F,Omilabu SA,Oyefolu AO,Berbers GA,Muller CP

更新日期：1999-07-01 00:00:00

abstract：:Helminthosporium victoriae virus 190S (HvV190S) is the type species of the genus Victorivirus under the family Totiviridae. To date, HvV190S has never been found in places outside of the USA and has Helminthosporium victoriae as its only know natural host fungus in the field. Here, we report the identification of 4 do...

journal_title：Virus research

authors： Wu R,Yang Y,Duan X,An H,Du Z,Zhang S,Zhang X

更新日期：2020-08-01 00:00:00

abstract：:Nearly 100 years after its discovery poliovirus remains one of most thoroughly studied and best understood virus models for the molecular virologist. While poliovirus has been of vital importance for our insight into picornavirus biology at the cellular and biochemical level, it is ironic to note that, due to the earl...

journal_title：Virus research

authors： Mueller S,Wimmer E,Cello J

更新日期：2005-08-01 00:00:00

abstract：:DMV, dolphin morbillivirus, a paramyxovirus of uncertain origin recently emerged in Mediterranean dolphins. This study presents the complete nucleotide sequence of the hemagglutinin (H) gene including the gene boundaries. The single open reading frame of the DMV H gene encodes a protein of 604 residues which exhibits ...

journal_title：Virus research

authors： Blixenkrone-Møller M,Bolt G,Jensen TD,Harder T,Svansson V

更新日期：1996-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV), a human herpesvirus, is linked to both epithelial and lymphoid malignancies. Induction of EBV reactivation is a potential therapeutic strategy for EBV-associated tumors. In this study, we assessed the effects of rapamycin on EBV reactivation in gastric carcinoma cells. We found that rapamycin...

journal_title：Virus research

authors： Wang M,Wu W,Zhang Y,Yao G,Gu B

更新日期：2018-01-15 00:00:00

abstract：:Viral replication and neutralization of hepatitis C viruses (HCV) have been studied using the infectious molecular clone JFH-1. By passaging JFH-1 in hepatoma cells in the absence or presence of HCV neutralizing antibodies (nAbs), we investigated the molecular mechanisms of cell-culture adaptation and sensitivity to n...

journal_title：Virus research

authors： Song H,Ren F,Li J,Shi S,Yan L,Gao F,Li K,Zhuang H

更新日期：2012-10-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In addition, RTA intera...

journal_title：Virus research

authors： Papugani A,Coleman T,Jones C,Zhang L

更新日期：2008-01-01 00:00:00

abstract：:Tick-borne encephalitis virus (TBEV) strains were isolated from ticks in Western Siberia for 12 years. Molecular hybridization of the 46 viral RNA with the TBEV cDNA and oligonucleotide probes revealed differences between the Siberian and Far Eastern strains. A comparison of the viral E gene fragment nucleotide sequen...

journal_title：Virus research

authors： Bakhvalova VN,Rar VA,Tkachev SE,Matveev VA,Matveev LE,Karavanov AS,Dobrotvorsky AK,Morozova OV

更新日期：2000-09-01 00:00:00