Abstract：
:The concentrations of the trace amines, m-tyramine, p-tyramine, phenylethylamine and tryptamine, were measured in the striatum of the brain and in the kidney of adult rats treated with alpha-monofluoromethyldopa (MFMD), an inhibitor of aromatic amino acid decarboxylase. While MFMD decreased the levels of all four amines in the kidney, only phenylethylamine and tryptamine levels were decreased in the striatum compared to control. Striatal p-tyramine levels were not affected, while striatal m-tyramine levels were increased by MFMD. When the rats were injected with a monoamine oxidase (MAO) inhibitor before MFMD administration, similar changes in striatal and kidney trace amine levels were observed compared to MFMD alone.
journal_name
Life Scijournal_title
Life sciencesauthors
Dyck LEdoi
10.1016/0024-3205(87)90371-7subject
Has Abstractpub_date
1987-02-09 00:00:00pages
571-5issue
6eissn
0024-3205issn
1879-0631pii
0024-3205(87)90371-7journal_volume
40pub_type
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