Lysis inhibition in Escherichia coli infected with bacteriophage T4.

abstract：:Poliovirus proteins, except P3-7c, are associated with the endoplasmic reticulum after extraction of the cytoplasm and centrifugation of membranes to equilibrium in sucrose gradients. Proteins P3-2, P2-X, and P3-9 are found preferentially among the rough endoplasmic reticulum, whereas P3-7c is located in smooth endopl...

journal_title：Journal of virology

authors： Tershak DR

更新日期：1984-12-01 00:00:00

abstract：:Mammalian cells infected with herpes simplex virus (HSV) express a novel ribonucleotide reductase which is biochemically and immunologically distinct from the uninfected-cell enzyme. Using polyvalent rabbit antiserum raised against partially purified HSV type 2 reductase as well as monoclonal antibodies to HSV type 1 ...

journal_title：Journal of virology

authors： Bacchetti S,Evelegh MJ,Muirhead B,Sartori CS,Huszar D

更新日期：1984-02-01 00:00:00

abstract：UNLABELLED:PD-1 is an inhibitory receptor that has a major role in T cell dysfunction during chronic infections and cancer. While demethylation of the PD-1 promoter DNA is observed in exhausted T cells isolated from chronically infected individuals, little is known about when this stable demethylation of PD-1 promoter ...

journal_title：Journal of virology

authors： Ahn E,Youngblood B,Lee J,Lee J,Sarkar S,Ahmed R

更新日期：2016-09-12 00:00:00

abstract：:The human T-cell leukemia virus type 1 (HTLV-1) envelope protein is required for virus spread. This study further characterizes the role of the envelope protein in HTLV-1 immortalization. Viruses with single amino acid substitutions within the SU protein at residue 75, 81, 95, 101, 105, or 195 or with a C-terminal cyt...

journal_title：Journal of virology

authors： Tsukahara T,Wielgosz MM,Ratner L

更新日期：2001-10-01 00:00:00

abstract：:The active site serine of the acetylesterase of influenza C virus was localized to amino acid 71 of the hemagglutinin-esterase protein by affinity labeling with 3H-labeled diisopropylfluorophosphate. This serine and the adjacent amino acids (Phe-Gly-Asp-Ser) are part of a consensus sequence motif found in serine hydro...

journal_title：Journal of virology

authors： Vlasak R,Muster T,Lauro AM,Powers JC,Palese P

更新日期：1989-05-01 00:00:00

abstract：:The limited efficiency of in vivo gene transfer by replication-deficient retroviral vectors remains an obstacle to achieving effective gene therapy for solid tumors. One approach to circumvent this problem is the use of replication-competent retroviral vectors. However, the application of such vectors is at a comparat...

journal_title：Journal of virology

authors： Paar M,Schwab S,Rosenfellner D,Salmons B,Günzburg WH,Renner M,Portsmouth D

更新日期：2007-07-01 00:00:00

abstract：UNLABELLED:Human noroviruses are icosahedral single-stranded RNA viruses. The capsid protein is divided into shell (S) and protruding (P) domains, which are connected by a flexible hinge region. There are numerous genetically and antigenically distinct noroviruses, and the dominant strains evolve every other year. Vacc...

journal_title：Journal of virology

authors： Koromyslova AD,Hansman GS

更新日期：2015-03-01 00:00:00

abstract：:The early steps of the intracellular trafficking of human papillomavirus type 16 (HPV-16), -31, and -58 pseudovirions were studied by investigating the effects of drugs acting at defined points of endocytosis pathways on virus-like particle-mediated pseudoinfection by overexpression of a dominant-negative form of the ...

journal_title：Journal of virology

authors： Bousarghin L,Touzé A,Sizaret PY,Coursaget P

更新日期：2003-03-01 00:00:00

abstract：:Dendritic cells (DCs) play a central role in instructing antiviral immune responses. DCs, however, can become targeted by different viruses themselves. We recently demonstrated that human DCs can be productively infected with echoviruses (EVs), but not coxsackie B viruses (CVBs), both of which are RNA viruses belongin...

journal_title：Journal of virology

authors： Kramer M,Schulte BM,Toonen LW,Barral PM,Fisher PB,Lanke KH,Galama JM,van Kuppeveld FJ,Adema GJ

更新日期：2008-03-01 00:00:00

abstract：:Fanconi anemia (FA) patients have an increased risk for squamous cell carcinomas (SCCs) at sites of predilection for infection with high-risk human papillomavirus (HPV) types, including the oral cavity and the anogenital tract. We show here that activation of the FA pathway is a frequent event in cervical SCCs. We fou...

journal_title：Journal of virology

authors： Spardy N,Duensing A,Charles D,Haines N,Nakahara T,Lambert PF,Duensing S

更新日期：2007-12-01 00:00:00

abstract：:The products of the A33R and A36R genes of vaccinia virus are incorporated into the membranes of intracellular enveloped virions (IEV). When extracts of cells that had been infected with vaccinia virus and labeled with H(3)(32)PO(4) were immunoprecipitated with antibodies against the A33R protein, two prominent bands ...

journal_title：Journal of virology

authors： Wolffe EJ,Weisberg AS,Moss B

更新日期：2001-01-01 00:00:00

abstract：:A hydrophilic region consisting of strikingly clustered charged amino acids is present at the center of human immunodeficiency virus type 1 (HIV-1) Vif. In this study, the role for this central hydrophilic region (E(88)WRKKR(93)) in the virus replication in nonpermissive H9 cells was investigated by extensive deletion...

journal_title：Journal of virology

authors： Fujita M,Sakurai A,Yoshida A,Miyaura M,Koyama AH,Sakai K,Adachi A

更新日期：2003-01-01 00:00:00

abstract：:We have analyzed the production of tumor necrosis factor alpha (TNF-alpha) induced by in vitro infection with African swine fever (ASF) virus (ASFV) and the systemic and local release of this inflammatory cytokine upon in vivo infection. An early increase in TNF-alpha mRNA expression was detected in ASFV-infected alve...

journal_title：Journal of virology

authors： Gómez del Moral M,Ortuño E,Fernández-Zapatero P,Alonso F,Alonso C,Ezquerra A,Domínguez J

更新日期：1999-03-01 00:00:00

abstract：UNLABELLED:Epstein-Barr virus (EBV) is a well-established B-cell-tropic virus associated with various lymphoproliferative diseases of both B-cell and non-B-cell origin. EBV is associated with a number of T-cell lymphomas; however, in vitro studies utilizing prototypical EBV type 1 (EBV-1) laboratory strains have genera...

journal_title：Journal of virology

authors： Coleman CB,Wohlford EM,Smith NA,King CA,Ritchie JA,Baresel PC,Kimura H,Rochford R

更新日期：2015-02-01 00:00:00

abstract：:The effects of human papillomavirus type 18 (HPV-18) E6 and E7 proteins on global patterns of host gene expression in primary human keratinocytes grown in organotypic raft culture system were assessed. Primary human keratinocytes were infected with retroviruses that express the wild-type HPV-18 E6 and E7 genes from th...

journal_title：Journal of virology

authors： Garner-Hamrick PA,Fostel JM,Chien WM,Banerjee NS,Chow LT,Broker TR,Fisher C

更新日期：2004-09-01 00:00:00

abstract：:Cells nonproductively transformed by a variant of the Snyder-Theilen strain of feline sarcoma virus (FeSV) expressed an 85,000-dalton polyprotein (P85) with associated tyrosine-specific protein kinase activity. We identified within this polyprotein a single tyrosine acceptor site for its enzyme activity. This acceptor...

journal_title：Journal of virology

authors： Blomberg J,Van de Ven WJ,Reynolds FH Jr,Nalewaik RP,Stephenson JR

更新日期：1981-06-01 00:00:00

abstract：:Recently, it was demonstrated that the coxsackievirus B3 variant PD (CVB3 PD) is able to infect coxsackievirus-adenovirus receptor (CAR)-lacking cells by using heparan sulfates (HS) as additional receptors (A. E. Zautner, U. Korner, A. Henke, C. Badorff, and M. Schmidtke, J. Virol. 77:10071-10077, 2003). For this stud...

journal_title：Journal of virology

authors： Zautner AE,Jahn B,Hammerschmidt E,Wutzler P,Schmidtke M

更新日期：2006-07-01 00:00:00

abstract：:Mouse cytomegalovirus (MCMV) encodes two potential seven-transmembrane-spanning proteins with homologies to cellular chemokine receptors, M33 and M78. While these virus-encoded chemokine receptors are necessary for the in vivo pathogenesis of MCMV, the function of these proteins is unknown. Since vascular smooth muscl...

journal_title：Journal of virology

authors： Melnychuk RM,Smith P,Kreklywich CN,Ruchti F,Vomaske J,Hall L,Loh L,Nelson JA,Orloff SL,Streblow DN

更新日期：2005-08-01 00:00:00

abstract：UNLABELLED:Enterovirus A71 (EV-A71) is a major cause of hand, foot, and mouth disease (HFMD) and is particularly prevalent in parts of Southeast Asia, affecting thousands of children and infants each year. Revealing the evolutionary and epidemiological dynamics of EV-A71 through time and space is central to understandi...

journal_title：Journal of virology

authors： Geoghegan JL,Tan le V,Kühnert D,Halpin RA,Lin X,Simenauer A,Akopov A,Das SR,Stockwell TB,Shrivastava S,Ngoc NM,Uyen le TT,Tuyen NT,Thanh TT,Hang VT,Qui PT,Hung NT,Khanh TH,Thinh le Q,Nhan le NT,Van HM,Viet do C

更新日期：2015-09-01 00:00:00

abstract：:The cytoplasmic domains of the transmembrane (TM) envelope proteins (TM-CDs) of most retroviruses have a Tyr-based motif, YXXO, in their membrane-proximal regions. This signal is involved in the trafficking and endocytosis of membrane receptors via clathrin-associated AP-1 and AP-2 adaptor complexes. We have used CD8-...

journal_title：Journal of virology

authors： Berlioz-Torrent C,Shacklett BL,Erdtmann L,Delamarre L,Bouchaert I,Sonigo P,Dokhelar MC,Benarous R

更新日期：1999-02-01 00:00:00

abstract：:A prerequisite for understanding the molecular function of the human cytomegalovirus (HCMV) gH (UL75)-gL (UL115) complex is a detailed knowledge of the structure of this complex in its functional form, as it is present in mature virions. The gH protein is known to be a component of a 240-kDa envelope complex designate...

journal_title：Journal of virology

authors： Huber MT,Compton T

更新日期：1997-07-01 00:00:00

abstract：:The human immunodeficiency virus (HIV) integrase protein (IN) catalyzes two reactions required to integrate HIV DNA into the human genome: 3' processing of the viral DNA ends and integration. IN has three domains, the N-terminal zinc-binding domain, the catalytic core, and the C-terminal SH3 domain. Previously, it was...

journal_title：Journal of virology

authors： van den Ent FM,Vos A,Plasterk RH

更新日期：1999-04-01 00:00:00

abstract：:Human immunodeficiency virus type 2 (HIV-2), like other lentiviruses, is capable of infecting nondividing T cells and macrophages. The present work shows that in HIV-2-infected cells, Vpx is necessary for efficient nuclear import of the preintegration complex. In agreement with this finding, the subcellular localizati...

journal_title：Journal of virology

authors： Pancio HA,Vander Heyden N,Ratner L

更新日期：2000-07-01 00:00:00

abstract：:A consensus binding site for the human papillomavirus (HPV) E2 protein was determined from an unbiased set of degenerate oligonucleotides using cyclic amplification and selection of targets (CASTing). Detectable DNA-protein complexes were formed after six to nine cycles of CASTing. A population of selected binding sit...

journal_title：Journal of virology

authors： Newhouse CD,Silverstein SJ

更新日期：2001-02-01 00:00:00

abstract：:We have evaluated the potential of conferring protective immunity to herpes simplex virus type 2 (HSV-2) by selectively inducing an HSV-specific CD8(+) cytotoxic T-lymphocyte (CTL) response directed against a single major histocompatibility complex class I-restricted CTL recognition epitope. We generated a recombinant...

journal_title：Journal of virology

authors： Blaney JE Jr,Nobusawa E,Brehm MA,Bonneau RH,Mylin LM,Fu TM,Kawaoka Y,Tevethia SS

更新日期：1998-12-01 00:00:00

abstract：:When herpes simplex virus was inoculated into the flank of a BALB/c mouse by scarification, the local replication of virus was followed by the establishment of an acute ganglionic infection. The subsequent centrifugal spread of this virus along nerves to the skin of the whole dermatome led to the development of a band...

journal_title：Journal of virology

authors： Simmons A,Nash AA

更新日期：1985-03-01 00:00:00

abstract：:Humans differ substantially with respect to susceptibility to human immunodeficiency virus type 1 (HIV-1). We evaluated variants of nine host genes participating in the viral life cycle for their role in modulating HIV-1 infection. Alleles were assessed ex vivo for their impact on viral replication in purified CD4 T c...

journal_title：Journal of virology

authors： Bleiber G,May M,Martinez R,Meylan P,Ott J,Beckmann JS,Telenti A,Swiss HIV Cohort Study.

更新日期：2005-10-01 00:00:00

abstract：:Varicella-zoster virus DNA was digested with 11 restriction endonucleases, and the resulting fragments were separated on agarose gels. Terminal fragments were identified by lambda exonuclease digestion. Physical maps were then constructed using a combination of double restriction enzyme digestion and hybridization to ...

journal_title：Journal of virology

authors： Mishra L,Dohner DE,Wellinghoff WJ,Gelb LD

更新日期：1984-05-01 00:00:00

abstract：:Transcription of herpesviral late genes is stimulated after the onset of viral DNA replication but otherwise restricted. Late gene expression in gammaherpesviruses requires the coordination of six early viral proteins, termed viral transactivation factors (vTFs). Here, we mapped the organization of this protein comple...

journal_title：Journal of virology

authors： Davis ZH,Hesser CR,Park J,Glaunsinger BA

更新日期：2015-10-14 00:00:00

abstract：:The EFII cis element is a 38-bp sequence at the 5' end of the Rous sarcoma virus long terminal repeat, extending from nucleotides -229 to -192 (with respect to the viral transcription start site), which is recognized by sequence-specific DNA-binding proteins in avian fibroblast nuclear extracts (L. Sealy and R. Chalkl...

journal_title：Journal of virology

authors： Sears RC,Sealy L

更新日期：1992-11-01 00:00:00