Abstract:
:The early steps of the intracellular trafficking of human papillomavirus type 16 (HPV-16), -31, and -58 pseudovirions were studied by investigating the effects of drugs acting at defined points of endocytosis pathways on virus-like particle-mediated pseudoinfection by overexpression of a dominant-negative form of the Eps15 protein to inhibit clathrin-mediated endocytosis and by electron microscopy. The results obtained suggested the involvement of clathrin-mediated endocytosis in HPV-16 and HPV-58 entry and caveola-mediated endocytosis in HPV-31 entry.
journal_name
J Viroljournal_title
Journal of virologyauthors
Bousarghin L,Touzé A,Sizaret PY,Coursaget Pdoi
10.1128/jvi.77.6.3846-3850.2003subject
Has Abstractpub_date
2003-03-01 00:00:00pages
3846-50issue
6eissn
0022-538Xissn
1098-5514journal_volume
77pub_type
杂志文章abstract::Recognition of virus infections by pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), retinoic acid-inducible gene I (RIG-I), and melanoma differentiation associated gene 5 (MDA5), activates signaling pathways, leading to the induction of inflammatory cytokines that limit viral replication. To d...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02008-08
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abstract::Cells that express glycoprotein D (gD) of herpes simplex virus type 1 (HSV-1) resist infection by HSV-1 and HSV-2 because of interference with viral penetration. The results presented here show that both HSV-1 and HSV-2 gD can mediate interference and that various HSV-1 and HSV-2 strains differ in sensitivity to this ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.69.8.5171-5176.1995
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abstract::In vivo decay rates for the individual T7 early mRNA species were determined. The physical half-lives, measured at 37 C, range from 1.1 min for gene 0.7 RNA to 4.5 min for gene 0.3 RNA. Physical half-lives, as observed after rifampin inhibition of RNA synthesis and polyacylamide electrophoresis of RNAs, are approximat...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.17.2.642-658.1976
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abstract::Chromatography of RNA polymerase purified from vaccinia virions and from vaccinia virus-infected HeLa cells resulted in the separation of populations active for early and late transcription. An RNA polymerase population immunodepleted for the vaccinia virus H4 gene peptide could support late transcription. ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.69.4.2602-2604.1995
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abstract::The Kresse strain of porcine parvovirus (PPV) was cloned into pUC19, and independent infectious clones were sequenced. The PPV Kresse and NADL-2 strains, which have different pathogenicities, shared an identical genomic organization and a high degree of sequence identity. Partial genomes (1.5 or 1.6 kb) of 15 field is...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.70.4.2508-2515.1996
更新日期:1996-04-01 00:00:00
abstract::The tegument of herpesviruses is a highly complex structural layer between the nucleocapsid and the envelope of virions. Tegument proteins play both structural and regulatory functions during replication and spread, but the interactions and functions of many of these proteins are poorly understood. Here we focus on tw...
journal_title:Journal of virology
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doi:10.1128/JVI.02196-16
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abstract::Vaccine-elicited humoral immune responses comprise an array of antibody forms and specificities, with only a fraction contributing to protective host immunity. Elucidation of antibody effector functions responsible for protective immunity against human immunodeficiency virus type 1 (HIV-1) acquisition is a major goal ...
journal_title:Journal of virology
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doi:10.1128/JVI.01552-17
更新日期:2018-03-14 00:00:00
abstract::Murine cytomegalovirus encodes three regulators of antigen presentation to antiviral CD8 T cells. According to current paradigms, all three regulators are committed to the inhibition of the presentation of antigenic peptides. Whereas m152/gp40 catalyzes the retention of peptide-loaded major histocompatibility complex ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00723-06
更新日期:2006-08-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.69.11.6925-6931.1995
更新日期:1995-11-01 00:00:00
abstract::The interaction of the mouse hepatitis virus (MHV) nucleocapsid protein (N) and viral RNA was examined. Monoclonal antibody specific for N protein coimmunoprecipitated MHV genomic RNA as well as all six MHV subgenomic mRNAs found in MHV-infected cells. In contrast, monoclonal antibodies to the MHV E2 or E1 envelope gl...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.62.11.4280-4287.1988
更新日期:1988-11-01 00:00:00
abstract::Varicella-zoster virus DNA was digested with 11 restriction endonucleases, and the resulting fragments were separated on agarose gels. Terminal fragments were identified by lambda exonuclease digestion. Physical maps were then constructed using a combination of double restriction enzyme digestion and hybridization to ...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.50.2.615-618.1984
更新日期:1984-05-01 00:00:00
abstract:UNLABELLED:Broadly neutralizing antibodies (bNAbs) specific for conserved epitopes on the HIV-1 envelope (Env) are believed to be essential for protection against multiple HIV-1 clades. However, vaccines capable of stimulating the production of bNAbs remain a major challenge. Given that polyreactivity and autoreactivit...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02904-14
更新日期:2015-04-01 00:00:00
abstract::Precursor polyproteins containing translational products of the gag gene of Moloney murine leukemia virus were purified by gel electrophoresis and cleaved into large fragments by hydroxylamine, mild acid hydrolysis, or cyanogen bromide. The hydroxylamine cleavage method (specific for asparagine-glycine bonds) was adap...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.46.3.841-859.1983
更新日期:1983-06-01 00:00:00
abstract::Analysis of the complete sequence of a human immunodeficiency virus (HIV) isolate (Ant70) obtained from a Cameroonian patient indicates that this virus is the most divergent strain within the HIV-1 family hitherto described. Comparison of the Pol protein, usually highly conserved within the HIV-1 family, shows only ab...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.68.3.1586-1596.1994
更新日期:1994-03-01 00:00:00
abstract::Lymphocyte antigen 6E (LY6E) is a GPI-anchored, interferon-inducible protein that has been shown to modulate viral infection in a cell type-dependent manner. Our recent work showed that LY6E promotes HIV-1 infection in some high-CD4-expressing cells, including human peripheral blood mononuclear cells (PBMCs) and the S...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.01866-18
更新日期:2019-03-21 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.77.19.10448-10455.2003
更新日期:2003-10-01 00:00:00
abstract::Infectious cDNA clones of mild (CHV1-Euro7) and severe (CHV1-EP713) hypovirus strains responsible for virulence attenuation (hypovirulence) of the chestnut blight fungus Cryphonectria parasitica were used to construct viable chimeric viruses. Differences in virus-mediated alterations of fungal colony morphology, growt...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.74.16.7562-7567.2000
更新日期:2000-08-01 00:00:00
abstract::An immunochemical analysis of the hemagglutinin (VP4) of the simian rotavirus SA11 was performed to better understand the structure and function of this molecule. Following immunization of mice with double-shelled virus particles and VP4-enriched fractions from CsCl gradients, a battery of anti-SA11 hybridomas was gen...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.62.6.2164-2172.1988
更新日期:1988-06-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.77.4.2615-2622.2003
更新日期:2003-02-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.46.2.626-628.1983
更新日期:1983-05-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.62.2.545-551.1988
更新日期:1988-02-01 00:00:00
abstract::Meq is the major Marek's disease virus (MDV)-encoded oncoprotein and is essential for T-cell lymphomagenesis. Meq and several noncoding RNAs, including three microRNA (MiR) clusters, are expressed from the repeats of the MDV genome during latent infection of T cells. To investigate the state of the chromatin in this a...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.06113-11
更新日期:2012-02-01 00:00:00
abstract::The N termini of the capsid proteins VP1 and VP2 of adeno-associated virus (AAV) play important roles in subcellular steps of infection and contain motifs that are highly homologous to a phospholipase A(2) (PLA(2)) domain and nuclear localization signals (NLSs). To more clearly understand how virion components influen...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.00687-10
更新日期:2010-09-01 00:00:00
abstract::The structural polypeptides of purified Plodia interpunctella granulosis virus were analyzed by three different two-dimensional gel systems. Isoelectric focusing followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis allowed resolution of 53 acidic polypeptides in the enveloped nucleocapsid of the virus...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.60.1.82-89.1986
更新日期:1986-10-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.02230-12
更新日期:2012-11-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.70.10.6653-6657.1996
更新日期:1996-10-01 00:00:00
abstract::Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible cells, and expression of the vpg15 marker is decreased in FIV-infected cells in vitro. These results suggest that the antib...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.67.3.1667-1671.1993
更新日期:1993-03-01 00:00:00
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journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.77.16.8812-8818.2003
更新日期:2003-08-01 00:00:00
abstract::Polydnaviridae is a unique family of DNA viruses that are symbiotically associated with parasitoid wasps. Upon oviposition, wasps inject these viruses into their hosts, where they cause several physiological alterations, including suppression of the cellular immune response. Here we report that expression of the glc1....
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/JVI.79.3.1861-1870.2005
更新日期:2005-02-01 00:00:00
abstract::The phosphoprotein (P protein) of respiratory syncytial virus (RSV) is a key component of the viral RNA-dependent RNA polymerase complex. The protein is constitutively phosphorylated at the two clusters of serine residues (116, 117, and 119 [116/117/119] and 232 and 237 [232/237]). To examine the role of phosphorylati...
journal_title:Journal of virology
pub_type: 杂志文章
doi:10.1128/jvi.76.21.10776-10784.2002
更新日期:2002-11-01 00:00:00