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The molecular weight of the endothelial cell IL-1 receptor is 78,000.

Abstract：

:Human endothelial cells have been shown to be distinctive from other IL-1 responsive cells (e.g. murine thymocytes), in the equal units of murine and human IL-1 do not have the same endothelial cell stimulatory effect, as measured by increased lymphocyte adherence. In this paper, the cell surface IL-1 receptors of human endothelial cells, fibroblasts and T-lymphocytes have been compared, to investigate whether endothelial cells have a unique receptor for IL-1. IL-1 receptors were isolated by both immunoprecipitation and chemical cross-linking to the ligand. Both techniques demonstrated that human endothelial cells are similar to human T-lymphocytes and fibroblasts, in that they all have a 78,000 mol. wt IL-1 receptor.

journal_name

Mol Immunol

journal_title

Molecular immunology

authors

Thieme TR,Wagner CR

doi

10.1016/0161-5890(89)90078-3

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

249-53

issue

3

eissn

0161-5890

issn

1872-9142

journal_volume

26

pub_type

杂志文章

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