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[CUN-BAE formula and biochemical factors as predictive markers of obesity and cardiovascular disease in patients before and after sleeve gastrectomy].

Abstract：

INTRODUCTION:Body Mass Index (BMI) is one of the most used parameters in bariatric surgery. However, it does not discriminate the weight associated with adiposity. CUN-BAE formula is an equation that calculates Body Fat Percentage or adiposity, based on easily available values (age, sex and BMI). With this new classification many of the subjects that was considered normal weight or overweight (BMI ≤30 kg/m2) really have a higher adiposity and they have comorbidities associated with obesity. The objective of this study is to evaluate the adiposity by formula CUN-BAE as a predictive marker of cardiovascular risk in morbidly obese patients before and after sleeve gastrectomy. MATERIAL AND METHODS:We performed a retrospective observational study of women that were intervened with sleeve gastrectomy, between 2007 and 2012 at the Universitary General Hospital of Elche. The adiposity was calculated by formula CUN-BAE preoperatively and 12 months after surgery. These values were correlated with different metabolic and cardiovascular risk parameters. RESULTS:50 women were studied. Preoperatively, the mean BMI was 50.4 ± 7 kg/m2 and adiposity 54.8 ± 3%. One year after surgery, the mean BMI was 27.7 ± 3 and adiposity 39.4 ± 4%. The adiposity was significantly correlated with 3 biochemical factors associated with increased cardiovascular risk (cortisol, vitamin D and ratio TG/HDL). CONCLUSION:Adiposity, according to the formula CUNBAE, and biochemical analysis of predictive factors of obesity together represent useful tools for assessing the risk of cardiovascular disease after sleeve gastrectomy. Introducción:Introducción: El Índice de Masa Corporal (IMC) es uno de los parámetros más utilizados en cirugía bariátrica. Sin embargo, no discrimina el peso asociado a adiposidad. La fórmula CUN-BAE es una ecuación que permite calcular el Porcentaje de Grasa Corporal (PGC) o adiposidad, basándose en valores fáciles de disponer (edad, sexo e IMC). Con esta nueva clasificación muchos de los sujetos considerados con normopeso o sobrepeso (IMC ≤30 kg/m2) en realidad tienen un PGC alto y presentan comorbilidades asociadas a la obesidad. El objetivo de este estudio es evaluar PGC cuantificado mediante fórmula CUN-BAE como marcador predictivo de riesgo cardiovascular en pacientes obesos mórbidos, antes y después de ser sometidos a Gastrectomía Vertical (GV). Material y métodos:Realizamos un estudio observacional retrospectivo de mujeres intervenidas de GV entre 2007 y 2012 en el Hospital General Universitario de Elche, calculando el PGC mediante la fórmula CUN-BAE de forma preoperatoria y 12 meses tras la intervención. Se correlacionaron estos valores con diferentes parámetros metabólicos y de riesgo cardiovascular. Resultados:Se estudiaron 50 mujeres. Preoperatoriamente, el IMC medio de 50,4 ± 7,4 kg/m2 y PGC del 54,8 ± 3%. Al año de la intervención, el IMC medio era de 27,7 ± 2,6 y el PGC 39,4 ± 3,7%. La PGC se correlacionó significativamente con 3 factores bioquímicos asociados con mayor riesgo cardiovascular (cortisol, vitamina D y cociente TG/HDL). Conclusión:la adiposidad, según la fórmula CUN-BAE, y el análisis de factores bioquímicos predictivos de obesidad, de forma conjunta suponen herramientas útiles para valorar el riesgo de enfermedad cardiovascular, después de GV.

journal_name

Nutr Hosp

journal_title

Nutricion hospitalaria

authors

Zubiaga Toro L,Ruiz-Tovar Polo J,Díez-Tabernilla M,Giner Bernal L,Arroyo Sebastián A,Calpena Rico R

doi

10.3305/nh.2014.30.2.7581

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

281-6

issue

eissn

0212-1611

issn

1699-5198

journal_volume

pub_type

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[CUN-BAE formula and biochemical factors as predictive markers of obesity and cardiovascular disease in patients before and after sleeve gastrectomy].