A 13-question approach to resolving serological discrepancies in the transfusion medicine laboratory.

abstract：BACKGROUND:Consanguineous marriage, a common practice in South India, increase the incidence of autosomal recessive diseases such as nonsyndromic hearing loss (NSHL) in offspring. This trend was noted in the children with hearing impairment (HI) who received cochlear implants (CI) at our University hospital in Porur, C...

journal_title：Laboratory medicine

authors： Arunachalam RK,Koshy T,Venkatesan V,Dawson GP,Franklin Durairaj Paul S,George P

更新日期：2020-01-02 00:00:00

abstract：:The main clinical distinction between post-transfusion purpura (PTP) and idiopathic thrombocytopenic purpura (ITP) is the sudden development of severe thrombocytopenia in the days after transfusion. Herein, we report the case of a 53-year-old Caucasian woman who developed multiple myeloma (MM) after peripheral blood-s...

journal_title：Laboratory medicine

authors： Milito C,Masel D,Henrichs K,Schmidt AE,Kirkley S,Aljitawi O,Becker M,Blumberg N,Refaai MA

更新日期：2019-10-10 00:00:00

abstract：OBJECTIVE:To determine and optimize the sensitivity of the CellaVision DM96 automated image-analysis system in detecting platelet (PLT) clumps on blood smears and to assess the reliability of the traditional laboratory practice of examining only the feather edge of the smear for PLT clumps. METHODS:We processed 102 bl...

journal_title：Laboratory medicine

authors： Gulati G,Uppal G,Florea AD,Gong J

更新日期：2014-10-01 00:00:00

abstract：Objective:To compare a manual squamous cell carcinoma antigen (SCCA) assay and an automated SCCA assay in a clinical setting. Methods:We included, in this study, a total of 158 specimens that had been tested using the manual SCCA assay. The CanAg SCC EIA assay and the Elecsys SCC were compared for their clinical setti...

journal_title：Laboratory medicine

authors： Lee S,Kim J,Uh Y,Kim HS,Lee JH

更新日期：2018-07-05 00:00:00

abstract：:Rhizobium radiobacter is an opportunistic, usually saprophytic, gram-negative bacillus found in agricultural soil. Isolation from blood has been reported most often in hospitalized patients harboring malignant neoplasms or human immunodeficiency virus (HIV) associated immunosuppression, who have catheter or medical de...

journal_title：Laboratory medicine

authors： Sawhney S,Naab T,Oneal P

更新日期：2016-08-01 00:00:00

abstract：PATIENT:47-year-old African American man. CHIEF COMPLAINT:Initially, serious finger abscess. The patient reported severe pain that was localized to that finger only. HISTORY OF PRESENT ILLNESS:His finger had become sore and then progressively more painful and swollen. PAST MEDICAL HISTORY:A few weeks earlier, the pa...

journal_title：Laboratory medicine

authors： Rausch S

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To analyze the performance characteristics, stability, and clinical value of lipoprotein-associated phospholipase A2 (Lp-PLA2) using an enzymatic kinetic method. METHODS:The performance characteristics included reference intervals, precision, and accuracy. We assessed Lp-PLA2 stability by comparing Lp-PLA2 c...

journal_title：Laboratory medicine

authors： Lu M,Lv L

更新日期：2019-07-16 00:00:00

abstract：:Storage pool deficiency (SPD) is a group of rare platelet disorders that result from deficiencies in α-granules, δ-granules, or both. One type of α-SPD is gray platelet syndrome (GPS), caused by mutations in the neurobeachin-like 2 (NBEAL2) gene that results in a bleeding diathesis, thrombocytopenia, splenomegaly, and...

journal_title：Laboratory medicine

authors： Riley R,Khan A,Pai S,Warmke L,Winkler M,Gunning W

更新日期：2019-10-10 00:00:00

abstract：PATIENT:78-year-old African-American man. PAST MEDICAL HISTORY:Chronic lymphocytic leukemia first diagnosed in 2003, with a subsequent relapse in 2006 and another in 2010. HISTORY OF PRESENT ILLNESS:In late 2011, the patient was admitted to the hospital for cholelithiasis, at which time his treating physician inciden...

journal_title：Laboratory medicine

authors： Sartori A,Staley B,Skipper A

更新日期：2014-07-01 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a form of lymphoplasmacytic lymphoma that can cause hyperviscosity syndrome due to unchecked monoclonal antibody production. Some patients are also found to have associated cryoglobulinemia, which can cause systemic complications including vasculitis, renal disease, and pulmonary ...

journal_title：Laboratory medicine

authors： Beech C,Kumar D,Hendrickson J,Perincheri S,Tormey C,Bahar B

更新日期：2019-07-16 00:00:00

abstract：Background:Early access for routine testing with the Alinity c clinical chemistry system (Abbot Laboratories) presented the opportunity to characterize the analytical performance of multiple analytes across clinical laboratories in Europe. Methods:A total of 8 laboratories from 7 European countries evaluated 10 high-v...

journal_title：Laboratory medicine

authors： Krintus M,Fernandez JA,Chesters C,Colla R,Ford C,Frattolillo D,Köller U,Mairesse J,Jimenez DM,Motol J,Padmore K,Sharrod-Cole H,Sypniewska G

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To establish a new indicator derived from reticulocyte hemoglobin (Ret-He) content and red blood cell (RBC) indices for screening for iron deficiency anemia (IDA) in an area in whch thalassemia is prevalent. METHODS:Blood specimens from 304 women aged between 18 and 30 years residing in northeast Thailand we...

journal_title：Laboratory medicine

authors： Jamnok J,Sanchaisuriya K,Chaitriphop C,Sanchaisuriya P,Fucharoen G,Fucharoen S

更新日期：2020-09-01 00:00:00

abstract：:Primary amoebic meningoencephalitis (PAM) is a rare and almost always fatal disease that is caused by Naegleria fowleri, a freshwater thermophilic amoeba. Our case involves an adolescent female who presented with fever of unknown origin. A lumbar puncture was performed, and the Wright-Giemsa and Gram stained cerebrosp...

journal_title：Laboratory medicine

authors： Dunn AL,Reed T,Stewart C,Levy RA

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Multirules are often employed to monitor quality control (QC). The performance of multirules is usually determined by simulation and is difficult to predict. Previous studies have not provided computer code that would enable one to experiment with multirules. It would be helpful for analysts to have computer...

journal_title：Laboratory medicine

authors： Walker BS,Pearson LN,Schmidt RL

更新日期：2020-01-02 00:00:00

abstract：BACKGROUND:Preparation of the patient for laboratory tests is crucial. Our aim was to investigate the current practice and regional variability of recommendations regarding patient preparation for laboratory testing. METHODS:A call for data was posted by email. Spanish laboratories were invited to fill out and submit ...

journal_title：Laboratory medicine

authors： Salinas M,López-Garrigós M,Flores E,Leiva-Salinas C

更新日期：2020-05-06 00:00:00

abstract：Objective:To determine the effect of presence of high concentrations of nicotinamide adenine dinucleotide (NADH)- and nicotinamide adenine dinucleotide phosphate (NADPH)-consuming enzymes on the accuracy of glutamate dehydrogenase (GLDH) assay for ammonia. Methods:We measured ammonia concentrations using GLDH and NADH...

journal_title：Laboratory medicine

authors： Vodenicarovova M,Skalska H,Holecek M

更新日期：2017-11-08 00:00:00

abstract：:Rivaroxaban (Xarelto; Johnson & Johnson Services, Inc) is a direct oral anticoagulant (DOAC) that works by directly inhibiting the active site of factor Xa (FXa). Rivaroxaban is metabolized and cleared via the kidney and liver. The results of various studies have shown that patients with severe renal impairment should...

journal_title：Laboratory medicine

authors： Milito C,McRae H,Victor A,Refaai MA,Schmidt AE

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:Oxidative stress has been associated with the progression of atherosclerosis and activation of genes that lead to increased deposition of proteins in the extracellular matrix. Bone sialoprotein (BSP) and osteonectin are proteins involved in the initiation and progression of vascular calcification. OBJECTIVE...

journal_title：Laboratory medicine

authors： Farrokhi E,Samani KG,Chaleshtori MH

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in urine with chronic kidney disease (CKD). METHODS:Case-control study including 50 patients with CKD and 20 healthy volunteers. RESULTS:SAM level and SAM/SAH ratio in urine were significantly lower in patients than i...

journal_title：Laboratory medicine

authors： Kruglova MP,Grachev SV,Bulgakova PO,Ivanov AV,Virus ED,Nikiforova KA,Fedoseev AN,Savina GD,Kubatiev AA

更新日期：2020-01-02 00:00:00

abstract：OBJECTIVE:To determine whether K2-ethylenediaminetetraacetic acid (EDTA) and K3-EDTA Greiner tubes could be used interchangeably for glycosylated hemoglobin, type A1C (HbA1c) measurement via the Abbott Laboratories ARCHITECT chemiluminescent microparticle HbA1c assay on the ARCHITECT i2000SR immunoanalyzer at our unive...

journal_title：Laboratory medicine

authors： Vrtaric A,Filipi P,Hemar M,Nikolac N,Simundic AM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The University of Maryland Medical System, like all other medical systems, is faced with providing the highest quality care in an environment of increased demands and competition for resources. Some responses to this pressure include improved integration, coordination, and efficiency. Laboratory integration ...

journal_title：Laboratory medicine

authors： Cook J

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Knowledge of transfusion medicine is the key element of better transfusion practices. This deficit observed at the blood bank end on daily basis exposing the patients for redundant risk. We assessed the knowledge of transfusion medicine among post intern doctors. OBJECTIVE:To assess the knowledge of transfu...

journal_title：Laboratory medicine

authors： Kumarage S,Fernando R,Gunasekara L

更新日期：2017-02-01 00:00:00

abstract：:Hormographiella is a rare fungal pathogen in humans; however, case reports have described disseminated infection in immunocompromised hosts. This pathogen has been described to yield poor prognosis in patients who harbor it. Herein, we present a case report of autopsy-proven disseminated Hormographiella aspergillata i...

journal_title：Laboratory medicine

authors： Chauhan A,Gruenberg J,Arbefeville S,Mettler T,Brent CH,Ferrieri P

更新日期：2019-10-10 00:00:00

abstract：OBJECTIVE:To evaluate broad-range 16S ribosomal DNA (rDNA) polymerase chain reaction (PCR) as a rapid screening tool to detect bacterial contamination of stem-cell products. METHODS:We performed the evaluation using whole blood spiked with serially diluted bacterial-type strains. Detection sensitivity was defined as t...

journal_title：Laboratory medicine

authors： Tokuno O,Hayakawa A,Yanai T,Mori T,Ohnuma K,Tani A,Minami H,Sugimoto T

更新日期：2015-01-01 00:00:00

abstract：:Myeloperoxidase (MPO) deficiency, one of the most common inherited phagocyte defects, and may exist as a transient phenomenon in combination with some clinical condition. Hematological analyzer ADVIA 2120i is used to identify the different types of leukocytes based on their size and staining properties, and by mean pe...

journal_title：Laboratory medicine

authors： Roh S,Ham JY,Song KE,Hwang N,Lee NY

更新日期：2020-03-10 00:00:00

abstract：PATIENT:44-year-old white woman. CHIEF COMPLAINTS:Cramping, nausea, shortness of breath, visual disturbances ("seeing yellow dots"). MEDICAL HISTORY:Status asthmticus, tobacco use, hypertension, migraines. PRINCIPLE LABORATORY FINDINGS:TABLES 1-7, FIGURES 1-4: . ...

journal_title：Laboratory medicine

authors： Bashiti O

更新日期：2016-02-01 00:00:00

abstract：:Herein, we present a case of extensive lymph node involvement by disseminated Cryptococcus infection developing in the immediate period after liver transplantation and initiation of immunosuppressive therapy. The patient, a 56 year old ethnicity unknown man, received a liver transplant for acute decompensated liver. B...

journal_title：Laboratory medicine

authors： Gilles SR,Arbefeville SS,Ferrieri P,Courville EL

更新日期：2018-07-05 00:00:00

abstract：:Cell-derived microparticles (MPs) are small fragments released from various cells when they are activated or undergo apoptosis. In the field of transfusion medicine, a number of studies have documented increased levels of MPs in blood products, which have been associated with multiple factors, including donor variabil...

journal_title：Laboratory medicine

authors： Noulsri E

更新日期：2020-09-01 00:00:00

abstract：Background:Thromboelastography (TEG) has become the standard of care in liver-transplant surgery to identify real-time abnormalities in the coagulation cascade. To our knowledge, no studies have been performed to measure the intrasubject reproducibility of TEG parameters in cirrhotic patients. Objective:To perform a v...

journal_title：Laboratory medicine

authors： George G,Manatasahit W,Balasubramanian M,Navarro V

更新日期：2018-07-05 00:00:00

abstract：:We report a case of a false-positive HIV result in an apparently healthy pregnant woman. Since no prenatal HIV testing had been performed, we screened for HIV reactivity utilizing the Architect HIV-Ag/Ab Combo assay. Results obtained were inconsistent in that they were repeatedly HIV reactive on a single serum sample ...

journal_title：Laboratory medicine

authors： Akl P,Blick KE

更新日期：2014-07-01 00:00:00