A system for automated noise parameter measurements on MR preamplifiers and application to high B(0) fields.

abstract：:The accuracy and precision of the quantification of metabolite concentrations in in vivo (1) H NMR spectroscopy are affected by linewidth and signal-to-noise ratio (SNR). To study the effect of both factors in in vivo (1) H NMR spectra acquired at ultrahigh field, a reference spectrum was generated by summing nine in ...

journal_title：NMR in biomedicine

authors： Hong ST,Pohmann R

更新日期：2013-01-01 00:00:00

abstract：:Spatiotemporally structured noise, such as physiological noise, is a potential source of artifacts in functional magnetic resonance imaging (fMRI) and is the main limiting factor for the detection of small blood oxygen level-dependent (BOLD) signal variations. fMRI was employed to detect low-frequency BOLD signal fluc...

journal_title：NMR in biomedicine

authors： Goerke U,Möller HE,Norris DG,Schwarzbauer C

更新日期：2005-12-01 00:00:00

abstract：:Determination of the apparent diffusion coefficient (ADC) of the prostate in men (n = 60) with raised prostate-specific antigen (PSA) or an abnormal digital rectal examination (DRE) prior to transrectal ultrasound (TRUS) guided biopsy using endorectal DWI is reported. Patients were categorized into different groups ba...

journal_title：NMR in biomedicine

authors： Kumar V,Jagannathan NR,Kumar R,Thulkar S,Gupta SD,Dwivedi SN,Hemal AK,Gupta NP

更新日期：2007-08-01 00:00:00

abstract：:Proton NMR spectroscopy of biological fluids has produced interesting results lately. We used the technique to investigate the effects of cryopreservation on primary porcine hepatocytes as successful cryopreservation of primary porcine hepatocytes is of importance to the development of bioartificial liver support syst...

journal_title：NMR in biomedicine

authors： Dabos KJ,Parkinson JA,Hewage C,Nelson LJ,Sadler IH,Hayes PC,Plevris JN

更新日期：2002-05-01 00:00:00

abstract：:Proton magnetic resonance spectroscopy (MRS) was employed to determine the concentrations of N-acetylaspartate (NAA), total creatine (tCr), choline-containing compounds (Cho), myo-inositol (Ins), glucose (Glc), and lactate (Lac) in rat brain before and after 10 days of oral supplementation of 2.6 g Cr-monohydrate per ...

journal_title：NMR in biomedicine

authors： Michaelis T,Wick M,Fujimori H,Matsumura A,Frahm J

更新日期：1999-08-01 00:00:00

abstract：INTRODUCTION:Sarcoidosis is a systemic granulomatous disease affecting in particular the respiratory tract. Cardiac magnetic resonance (CMR), including a measurement of T1 relaxation time, could potentially detect early stadia of sarcoidosis of the heart. The study aims to assess T1 mapping in the detection of early ca...

journal_title：NMR in biomedicine

authors： Panovský R,Doubková M,Holeček T,Máchal J,Feitová V,Masárová L,Opatřil L,Mojica-Pisciotti ML,Kincl V

更新日期：2020-11-01 00:00:00

abstract：:This study aimed to demonstrate a reliable automatic segmentation method for independently separating reduced diffusion and decreased perfusion areas in ischemic stroke brains using constrained nonnegative matrix factorization (cNMF) pattern recognition in directional intravoxel incoherent motion MRI (IVIM-MRI). First...

journal_title：NMR in biomedicine

authors： Jang M,Jin S,Kang M,Han S,Cho H

更新日期：2020-05-01 00:00:00

abstract：:One of the major goals of hyperpolarized-gas MR imaging has been to obtain (129)Xe dissolved-phase images in humans. Since the dissolved-phase signal is much weaker than the gas-phase signal, highly optimized MR pulse sequences are required to obtain adequate images during a single breath-hold. In particular, a solid ...

journal_title：NMR in biomedicine

authors： Ruppert K,Brookeman JR,Hagspiel KD,Driehuys B,Mugler JP 3rd

更新日期：2000-06-01 00:00:00

abstract：:The aim of the study was to establish the normal range and to evaluate the reproducibility of dynamic contrast enhanced MRI (DCE-MRI) parameter estimates in normal human pelvic tissues. Nineteen patients with prostate cancer, undergoing androgen deprivation treatment, had paired DCE-MRI examinations of the pelvis usin...

journal_title：NMR in biomedicine

authors： Padhani AR,Hayes C,Landau S,Leach MO

更新日期：2002-04-01 00:00:00

abstract：:The purpose of this paper is to facilitate the comparison of magnetic resonance (MR) spectra acquired from unknown brain lesions with published spectra in order to help identify unknown lesions in clinical settings. The paper includes lists of references for published MR spectra of various brain diseases, including py...

journal_title：NMR in biomedicine

authors： Kingsley PB,Shah TC,Woldenberg R

更新日期：2006-06-01 00:00:00

abstract：:Metabolomic studies by NMR spectroscopy are increasingly employed for a variety of biomedical applications. A very standardized 1D proton NMR protocol is generally employed for data acquisition, associated with multivariate statistical tests. Even if targeted approaches have been proposed to quantify metabolites from ...

journal_title：NMR in biomedicine

authors： Martineau E,Tea I,Akoka S,Giraudeau P

更新日期：2012-08-01 00:00:00

abstract：:Two FDA-approved agents, ferumoxides (Feridex), a suspension of superparamagnetic iron oxide (SPIO) nanoparticles and protamine sulfate, a drug used to reverse heparin anticoagulation, can be complexed and used to label cells magnetically ex vivo. Labeling stem cells with ferumoxides-protamine sulfate (FePro) complexe...

journal_title：NMR in biomedicine

authors： Arbab AS,Yocum GT,Rad AM,Khakoo AY,Fellowes V,Read EJ,Frank JA

更新日期：2005-12-01 00:00:00

abstract：:The current study aims to evaluate the feasibility of creatine (Cr) chemical exchange saturation transfer (CEST)-weighted MRI at 7 T in the human brain by optimizing the saturation pulse parameters and computing contrast using a Z-spectral fitting approach. The Cr-weighted (Cr-w) CEST contrast was computed from phanto...

journal_title：NMR in biomedicine

authors： Singh A,Debnath A,Cai K,Bagga P,Haris M,Hariharan H,Reddy R

更新日期：2019-12-01 00:00:00

abstract：:Reconstruction of MRI data is based on exact knowledge of all magnetic field dynamics, since the interplay of RF and gradient pulses generates the signal, defines the contrast and forms the basis of resolution in spatial and spectral dimensions. Deviations caused by various sources, such as system imperfections, delay...

journal_title：NMR in biomedicine

authors： Brunner DO,Dietrich BE,Çavuşoğlu M,Wilm BJ,Schmid T,Gross S,Barmet C,Pruessmann KP

更新日期：2016-09-01 00:00:00

abstract：:MRI detects changes in blood-oxygenation-level dependent (BOLD) contrast in tumors caused by tumor oxygenating agents. These changes can be used to guide the design of improved tumor oxygenating treatments (TOXs). The conventional approach to detection of BOLD effects assumes that the water resonance is a single, homo...

journal_title：NMR in biomedicine

authors： Al-Hallaq HA,Fan X,Zamora M,River JN,Moulder JE,Karczmar GS

更新日期：2002-02-01 00:00:00

abstract：:A review of the theory, technology, and use of radio frequency (RF) coils for small-animal MRI is presented. It includes a brief overview of MR signal-to-noise (S/N) analysis and discussions of the various coils commonly used in small-animal MR: surface coils, linear volume coils, birdcages, and their derivatives. The...

journal_title：NMR in biomedicine

authors： Doty FD,Entzminger G,Kulkarni J,Pamarthy K,Staab JP

更新日期：2007-05-01 00:00:00

abstract：:In this study, metabolic changes in the 79A/C3H, ME7/VM, ME7/C3H, 87V/VM and 22A/SV scrapie mouse models were investigated during the clinical phase of the disease, using in vitro proton nuclear magnetic resonance spectroscopy. N-acetyl-aspartate was found to be significantly reduced in infected mice of the ME7/ C3H (...

journal_title：NMR in biomedicine

authors： Chung YL,Williams A,Chong A,Hope J,Williams SC,Bell JD

更新日期：1996-12-01 00:00:00

abstract：:The availability of high-field-strength magnetic resonance imaging (MRI) systems has brought about the development of techniques that aim to map myelination via the exploitation of various contrast mechanisms. Myelin mapping techniques have the potential to provide tools for the diagnosis and treatment of diseases, su...

journal_title：NMR in biomedicine

authors： Ziser L,Meyer-Schell N,Kurniawan ND,Sullivan R,Reutens D,Chen M,Vegh V

更新日期：2018-03-01 00:00:00

abstract：:The present work aims to show the applicability of an analytical model for the optimisation of the STEAM sequence timing parameters for lactate detection at ultra high-field. The effects of the chemical shift displacement artefact on the J-modulated signal for a weakly-coupled spin system were considered in the three ...

journal_title：NMR in biomedicine

authors： Fernandes CC,Lanz B,Chen C,Morris PG,Salmon CG

更新日期：2020-11-02 00:00:00

abstract：:This review highlights various magnetic resonance image (MRI) segmentation algorithms that employ pattern recognition. The procedures are grouped into two categories: low- to intermediate-level, and high-level image processing. The former consists of grey level histogram analysis, texture definition, edge identificati...

journal_title：NMR in biomedicine

authors： Saeed N

更新日期：1998-06-01 00:00:00

abstract：:Previous studies have demonstrated that using hyperpolarized [2-13 C]pyruvate as a contrast agent can reveal 13 C signals from metabolites associated with the tricarboxylic acid (TCA) cycle. However, the metabolites detectable from TCA cycle-mediated oxidation of [2-13 C]pyruvate are the result of several metabolic st...

journal_title：NMR in biomedicine

authors： Chen AP,Lau AZ,Gu YP,Schroeder MA,Barry J,Cunningham CH

更新日期：2018-01-01 00:00:00

abstract：:In many studies, it has been demonstrated that (1)H MRSI of the human prostate has great potential to aid prostate cancer management, e.g. in the detection and localisation of cancer foci in the prostate or in the assessment of its aggressiveness. It is particularly powerful in combination with T2 -weighted MRI. Never...

journal_title：NMR in biomedicine

authors： Kobus T,Wright AJ,Scheenen TW,Heerschap A

更新日期：2014-01-01 00:00:00

abstract：:Nonbiological total disc replacement is currently being used for the treatment of intervertebral disc (IVD) disease and injury, but these implants are prone to mechanical wear, tear and possible dislodgement. Recently, tissue-engineered total disc replacement (TE-TDR) has been investigated as a possible alternative to...

journal_title：NMR in biomedicine

authors： Bowles RD,Gebhard HH,Dyke JP,Ballon DJ,Tomasino A,Cunningham ME,Härtl R,Bonassar LJ

更新日期：2012-03-01 00:00:00

abstract：:The steady-state distribution of the general anesthetic halothane in different rat tissues, including a renal adenocarcinoma with and without hyperthermia treatment, has been evaluated by in vivo 19F NMR spectroscopy. The 19F spectra of halothane (which is a hydrophobic probe) from within tissue show differences in th...

journal_title：NMR in biomedicine

authors： Burt CT,Moore RR,Roberts MF

更新日期：1993-09-01 00:00:00

abstract：:In this work, we report a case study of a stroke model in animals using two methods of quantification of the deviations from Gaussian behaviour: diffusion kurtosis imaging (DKI) and log-normal distribution function imaging (LNDFI). The affected regions were predominantly in grey rather than in white matter. The parame...

journal_title：NMR in biomedicine

authors： Grinberg F,Ciobanu L,Farrher E,Shah NJ

更新日期：2012-11-01 00:00:00

abstract：:Obesity causes damage to several organs, including the brain. Recent studies have been focusing on understanding the mechanisms through which obesity affects brain structure and function using neuroimaging techniques. A functional biomarker, such as cerebral blood flow (CBF), is a powerful tool that can be used to exp...

journal_title：NMR in biomedicine

authors： Peng SL,Chen CM

更新日期：2020-10-01 00:00:00

abstract：:Given the importance of genetically modified mice in studies of mammalian brain development and human congenital brain diseases, MRI has the potential to provide an efficient in vivo approach for analyzing mutant phenotypes in the early postnatal mouse brain. The combination of reduced tissue contrast at the high magn...

journal_title：NMR in biomedicine

authors： Wadghiri YZ,Blind JA,Duan X,Moreno C,Yu X,Joyner AL,Turnbull DH

更新日期：2004-12-01 00:00:00

abstract：:An indirect method for in vivo T2 mapping of 13 C-labeled metabolites using T2 and T2 * information of water protons obtained a priori is proposed. The T2 values of 13 C metabolites are inferred using the relationship to T2 ' of coexisting 1 H and the T2 * of 13 C metabolites, which is measured using routine hyperpola...

journal_title：NMR in biomedicine

authors： Joe E,Lee H,Lee J,Yang S,Choi YS,Wang E,Song HT,Kim DH

更新日期：2017-05-01 00:00:00

abstract：:T2 relaxation time is a quantitative MRI in vivo surrogate of cerebral tissue damage in multiple sclerosis (MS) patients. Cortical T2 prolongation is a known feature in later disease stages, but has not been demonstrated in the cortical normal appearing gray matter (NAGM) in early MS. This study centers on the quantit...

journal_title：NMR in biomedicine

authors： Gracien RM,Reitz SC,Hof SM,Fleischer V,Zimmermann H,Droby A,Steinmetz H,Zipp F,Deichmann R,Klein JC

更新日期：2016-04-01 00:00:00

abstract：:A special characteristic of the brain is the usage of lactate as alternative fuel instead of glucose to preserve its energy homeostasis. This physiological function is valid for sufficient cerebral glucose supply, as well as presumably during hypoglycemia, given that exogenous lactate infusion suppresses hormonal coun...

journal_title：NMR in biomedicine

authors： Richter J,Rabe D,Duysen K,Melchert UH,Oltmanns KM

更新日期：2019-11-01 00:00:00