NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold.

abstract：:Metabolomic studies by NMR spectroscopy are increasingly employed for a variety of biomedical applications. A very standardized 1D proton NMR protocol is generally employed for data acquisition, associated with multivariate statistical tests. Even if targeted approaches have been proposed to quantify metabolites from ...

journal_title：NMR in biomedicine

authors： Martineau E,Tea I,Akoka S,Giraudeau P

更新日期：2012-08-01 00:00:00

abstract：:Increased sensitivity and chemical shift dispersion at ultra-high magnetic fields enable the precise quantification of an extended range of brain metabolites from (1)H MRS. However, all previous neurochemical profiling studies using single-voxel MRS at 7 T have been limited to data acquired from the occipital lobe wit...

journal_title：NMR in biomedicine

authors： Emir UE,Auerbach EJ,Van De Moortele PF,Marjańska M,Uğurbil K,Terpstra M,Tkáč I,Oz G

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to acquire high-quality in vivo (1) H spectra concurrently from two voxels at ultra-high field (7 T) without specialized hardware. To this end, an acquisition scheme was developed in which first-order shims and flip angles are dynamically updated to acquire spectra from both of the brain's mo...

journal_title：NMR in biomedicine

authors： Lemke C,Hess A,Clare S,Bachtiar V,Stagg C,Jezzard P,Emir U

更新日期：2015-07-01 00:00:00

abstract：:The reliability, relation to whole-body maximal oxygen uptake (VO(2max)), and force-level sensitivity of (31)P MRS markers of mitochondrial function were studied in 39 normal-weight women. Following 90 s isometric plantar-flexion exercises at 45, 70 and 100% of maximum voluntary contraction, skeletal muscle mitochondr...

journal_title：NMR in biomedicine

authors： Larson-Meyer DE,Newcomer BR,Hunter GR,Hetherington HP,Weinsier RL

更新日期：2000-01-01 00:00:00

abstract：:The applications of in vivo electron paramagnetic resonance (EPR) or electron spin resonance (ESR) spectroscopy have been impressive over a relatively short period despite the many obstacles which had to be overcome, such as dielectric absorption and biodestruction. The loop-gap resonators and modified loop coil syste...

journal_title：NMR in biomedicine

authors： Fujii H,Berliner LJ

更新日期：2004-08-01 00:00:00

abstract：:This paper describes the use of off-resonance saturation to further manipulate the blood oxygenation level dependent (BOLD) contrast of fMRI. A customized narrow bandwidth radiofrequency pulse, applied with a range of frequency offsets prior to selection of each slice, was designed and incorporated into a gradient ech...

journal_title：NMR in biomedicine

authors： Song AW,Wolff SD,Balaban RS,Jezzard P

更新日期：1997-06-01 00:00:00

abstract：:The progression of Parkinson's disease (PD) seems to vary according to the disease stage, which greatly influences the management of PD patients. However, the underlying mechanism of progression in PD remains unclear. This study was designed to explore the progressive pattern of iron accumulation at different stages i...

journal_title：NMR in biomedicine

authors： Guan X,Xuan M,Gu Q,Huang P,Liu C,Wang N,Xu X,Luo W,Zhang M

更新日期：2017-04-01 00:00:00

abstract：:In imaging of human lungs with hyperpolarised noble gases, measurements of apparent diffusion coefficient (ADC) and relaxation time provide valuable information for the assessment of lung microstructure. In this work, a sequence was developed for interleaved acquisition of ventilation images, ADC, T(2)* and flip angle...

journal_title：NMR in biomedicine

authors： Ajraoui S,Parra-Robles J,Marshall H,Deppe MH,Clemence M,Wild JM

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study is to fabricate and test a novel flexible flat cable antenna (FFCA) for MRI of the knee at different flexion angles. The FFCA was made of a flat cable, a tuning/matching circuit and a signal transmission line. To test its feasibility and validity, in vitro and in vivo experiments were carried out...

journal_title：NMR in biomedicine

authors： Jia F,Yuan H,Zhou D,Zhang J,Wang X,Fang J

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To develop a novel respiratory motion compensated three-dimensional (3D) cardiac magnetic resonance fingerprinting (cMRF) approach for whole-heart myocardial T1 and T2 mapping from a free-breathing scan. METHODS:Two-dimensional (2D) cMRF has been recently proposed for simultaneous, co-registered T1 and T2 mapp...

journal_title：NMR in biomedicine

authors： Cruz G,Jaubert O,Qi H,Bustin A,Milotta G,Schneider T,Koken P,Doneva M,Botnar RM,Prieto C

更新日期：2020-10-01 00:00:00

abstract：:During magnetic resonance imaging (MRI) examinations, the average specific absorption rate (SAR) of the whole body is calculated as an index of global energy deposition in biological tissue without taking into account the presence of metallic implants or conductive materials. However, this global SAR calculation is no...

journal_title：NMR in biomedicine

authors： Saniour I,Gaborit G,Perrier AL,Gillette L,Revillod G,Sablong R,Duvillaret L,Beuf O

更新日期：2018-01-01 00:00:00

abstract：:Qualitative and quantitative (1) H NMR analysis of lipid extracts of gallbladder tissue in chronic cholecystitis (CC, benign) (n = 14), xanthogranulomatous cholecystitis (XGC, intermediate) (n = 9) and gallbladder cancer (GBC, malignant) (n = 8) was carried out to understand the mechanisms involved in the transformati...

journal_title：NMR in biomedicine

authors： Jayalakshmi K,Sonkar K,Behari A,Kapoor VK,Sinha N

更新日期：2011-05-01 00:00:00

abstract：:In the unstimulated brain energy is primarily supplied by the oxidation of glucose. However the oxygen-to-glucose index (OGI), which is the ratio of metabolic rates of oxygen to glucose, CMR(O2)/CMR(glc), diverges from the theoretical value of 6 as activity is increased. In vivo measurements of brain lactate show its ...

journal_title：NMR in biomedicine

authors： Shulman RG,Hyder F,Rothman DL

更新日期：2001-11-01 00:00:00

abstract：:133Cs NMR is a valuable tool for non-invasively probing biological systems. As a congener of potassium, it accumulates in the intracellular space, primarily through the action of the Na+-K+ pump (ATPase). In addition, it is possible to resolve the MR signal of 133Cs in different tissue compartments on the basis of che...

journal_title：NMR in biomedicine

authors： Goodman J,Neil JJ,Ackerman JJ

更新日期：2005-04-01 00:00:00

abstract：:Free cytosolic [Mg2+] can be assessed in vivo by 31P MRS from the chemical shift of beta-ATP which in turn depends on the fraction of total ATP complexed to Mg2+ ions. The reliability of these in vivo measurements depends on the availability of an appropriate in vitro calibration to determine the limits of chemical sh...

journal_title：NMR in biomedicine

authors： Iotti S,Frassineti C,Alderighi L,Sabatini A,Vacca A,Barbiroli B

更新日期：1996-02-01 00:00:00

abstract：:The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and their metabolites efficiently, for which specialized imaging sequences are required. In this work, a multi-echo balanced steady-state free precession (me-bSSFP) sequence with Iterative Decomposition with Echo Asymmetry and Leas...

journal_title：NMR in biomedicine

authors： Müller CA,Hundshammer C,Braeuer M,Skinner JG,Berner S,Leupold J,Düwel S,Nekolla SG,Månsson S,Hansen AE,von Elverfeldt D,Ardenkjaer-Larsen JH,Schilling F,Schwaiger M,Hennig J,Hövener JB

更新日期：2020-06-01 00:00:00

abstract：:Chemical exchange saturation transfer (CEST)-derived, pH-weighted, amide proton transfer (APT) MRI has shown promise in animal studies for the prediction of infarction risk in ischemic tissue. Here, APT MRI was translated to patients with acute stroke (1-24 h post-symptom onset), and assessments of APT contrast, perfu...

journal_title：NMR in biomedicine

authors： Tietze A,Blicher J,Mikkelsen IK,Østergaard L,Strother MK,Smith SA,Donahue MJ

更新日期：2014-02-01 00:00:00

abstract：:A quantitative magnetization transfer (qMT) technique was employed to quantify the ratio of the sizes of the bound and free water proton pools in ex vivo mouse brains. The goal was to determine the pool size ratio sensitivity to myelin. Fixed brains from both shiverer mice and control littermates were imaged. The pool...

journal_title：NMR in biomedicine

authors： Ou X,Sun SW,Liang HF,Song SK,Gochberg DF

更新日期：2009-06-01 00:00:00

abstract：:Glucose metabolism in control and estrogen stimulated rat uteri was investigated using 13C NMR spectroscopy. By employing an NMR adapted perifusion system, and developing protocols and methods based on the application of [1-13C]glucose labeling, it was possible to measure, with a temporal resolution of 10 min, the kin...

journal_title：NMR in biomedicine

authors： Shinkarenko L,Kaye AM,Degani H

更新日期：1994-08-01 00:00:00

abstract：:This paper compares two spectral processing methods for obtaining quantitative measures from in vivo prostate spectra, evaluates their effectiveness, and discusses the necessary modifications for accurate results. A frequency domain analysis (FDA) method based on peak integration was compared with a time domain fittin...

journal_title：NMR in biomedicine

authors： Pels P,Ozturk-Isik E,Swanson MG,Vanhamme L,Kurhanewicz J,Nelson SJ,Van Huffel S

更新日期：2006-04-01 00:00:00

abstract：:An MR thermometry method is proposed for measuring in vivo small temperature changes engendered by external RF heat sources. The method relies on reproducible and stable respiration and therefore currently applies to ventilated animals whose breathing is carefully controlled. It first consists in characterizing the st...

journal_title：NMR in biomedicine

authors： Boulant N,Bottlaender M,Uhrig L,Giacomini E,Luong M,Amadon A,Massire A,Larrat B,Vignaud A

更新日期：2015-01-01 00:00:00

abstract：:In this study, Blood Oxygenation Level Dependent (BOLD) contrast in the detection of human brain activation was compared between spin-echo and gradient-echo echo-planar sequences at 1.5 T. Time course series of spin-echo and gradient-echo images containing the primary motor cortex were collected during rest (no finger...

journal_title：NMR in biomedicine

authors： Bandettini PA,Wong EC,Jesmanowicz A,Hinks RS,Hyde JS

更新日期：1994-03-01 00:00:00

abstract：:In order to keep subscribers up-to-date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of NMR in biomedicine. Each bibliography is divided into 9 sections: 1 Books, Re...

journal_title：NMR in biomedicine

authors： Wennerberg AB,Jonsson T,Forssberg H,Li TQ

更新日期：2001-02-01 00:00:00

abstract：:In this study, metabolic changes in the 79A/C3H, ME7/VM, ME7/C3H, 87V/VM and 22A/SV scrapie mouse models were investigated during the clinical phase of the disease, using in vitro proton nuclear magnetic resonance spectroscopy. N-acetyl-aspartate was found to be significantly reduced in infected mice of the ME7/ C3H (...

journal_title：NMR in biomedicine

authors： Chung YL,Williams A,Chong A,Hope J,Williams SC,Bell JD

更新日期：1996-12-01 00:00:00

abstract：:An indirect method for in vivo T2 mapping of 13 C-labeled metabolites using T2 and T2 * information of water protons obtained a priori is proposed. The T2 values of 13 C metabolites are inferred using the relationship to T2 ' of coexisting 1 H and the T2 * of 13 C metabolites, which is measured using routine hyperpola...

journal_title：NMR in biomedicine

authors： Joe E,Lee H,Lee J,Yang S,Choi YS,Wang E,Song HT,Kim DH

更新日期：2017-05-01 00:00:00

abstract：:The relaxation properties of water and metabolites were measured in rat brain following the occlusion of the middle cerebral artery (MCA) with localized 1H MRS. The PRESS sequence was employed to select volumes of 39 microL in the ischemic and the contralateral hemisphere. T1 and T2 relaxation times and peak intensiti...

journal_title：NMR in biomedicine

authors： van der Toorn A,Dijkhuizen RM,Tulleken CA,Nicolay K

更新日期：1995-09-01 00:00:00

abstract：:The goal of the study was to establish early hyperpolarized (HP) 13 C MRI metabolic and perfusion changes that predict effective high-intensity focused ultrasound (HIFU) ablation and lead to improved adjuvant treatment of partially treated regions. To accomplish this a combined HP dual-agent (13 C pyruvate and 13 C ur...

journal_title：NMR in biomedicine

authors： Lee JE,Diederich CJ,Bok R,Sriram R,Santos RD,Noworolski SM,Salgaonkar VA,Adams MS,Vigneron DB,Kurhanewicz J

更新日期：2019-10-01 00:00:00

abstract：:Transceiver surface coil arrays improve transmit performance (B1/√kW) and B1 homogeneity for head imaging up to 9.4 T. To further improve reception performance and parallel imaging, the number of array elements must be increased with a corresponding decrease in their size. With a large number of small interacting ante...

journal_title：NMR in biomedicine

authors： Avdievich NI,Pan JW,Hetherington HP

更新日期：2013-11-01 00:00:00

abstract：:Cross-talk between adipose tissue and liver is disturbed in the metabolic syndrome. Moreover, the relative fatty acid composition of adipose and liver fat is poorly characterized. Long-TE (1)H MRS can determine the unsaturation and polyunsaturation of adipose tissue. The aim of this study was to use long-TE (1)H MRS t...

journal_title：NMR in biomedicine

authors： Lundbom J,Hakkarainen A,Söderlund S,Westerbacka J,Lundbom N,Taskinen MR

更新日期：2011-04-01 00:00:00

abstract：:A number of NMR spectroscopic and microscopic MRI (microMRI) techniques were used to study proton dynamics in canine tendon and articular cartilage immersed in normal saline solution (NaCl solution) and high-concentration phosphate-buffered saline (PBS) solution. In a proton CPMG experiment on tendons, the T(2) relaxa...

journal_title：NMR in biomedicine

authors： Zheng S,Xia Y

更新日期：2009-02-01 00:00:00