听力与言语-语言病理学

行为科学

医学伦理学

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  • Quantification of disease progression in spinal muscular atrophy with muscle MRI-a pilot study.

    abstract:OBJECTIVES:Quantitative MRI (qMRI) of muscles is a promising tool to measure disease progression or to assess therapeutic effects in neuromuscular diseases. Longitudinal imaging studies are needed to show sensitivity of qMRI in detecting disease progression in spinal muscular atrophy (SMA). In this pilot study we there...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4473

    authors: Otto LAM,Froeling M,van Eijk RPA,Asselman FL,Wadman R,Cuppen I,Hendrikse J,van der Pol WL

    更新日期:2021-01-22 00:00:00

  • The effect of maternal position on venous return for pregnant women during MRI.

    abstract::Magnetic resonance imaging (MRI) in pregnancy is commonly undertaken in the left lateral tilt (LLT) position to prevent inferior vena cava (IVC) compression and supine hypotensive events, although this may be suboptimal for image quality. The supine position may also have an adverse effect on fetal well-being. The spi...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4475

    authors: Hughes EJ,Price AN,McCabe L,Hiscocks S,Waite L,Green E,Hutter J,Pegoretti K,Cordero-Grande L,Edwards DA,Hajnal JV,Rutherford MA

    更新日期:2021-01-21 00:00:00

  • The impact of edema and fiber crossing on diffusion MRI metrics assessed in an ex vivo nerve phantom: Multi-tensor model vs. diffusion orientation distribution function.

    abstract::Diffusion tensor imaging (DTI) has been employed for over 2 decades to noninvasively quantify central nervous system diseases/injuries. However, DTI is an inadequate simplification of diffusion modeling in the presence of coexisting inflammation, edema and crossing nerve fibers. We employed a tissue phantom using fixe...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4414

    authors: Ye Z,Gary SE,Sun P,Mustafi SM,Glenn GR,Yeh FC,Merisaari H,Song C,Yang R,Huang GS,Kao HW,Lin CY,Wu YC,Jensen JH,Song SK

    更新日期:2021-01-01 00:00:00

  • In silico GABA+ MEGA-PRESS: Effects of signal-to-noise ratio and linewidth on modeling the 3 ppm GABA+ resonance.

    abstract::To investigate the GABA+ modeling accuracy of MEGA-PRESS GABA+-edited MRS data with various spectral quality scenarios, the influence of varying signal-to-noise ratio (SNR) and linewidth on the model estimates was quantified. MEGA-PRESS data from 46 volunteers were averaged to generate a template MEGA-PRESS spectrum, ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4410

    authors: Zöllner HJ,Oeltzschner G,Schnitzler A,Wittsack HJ

    更新日期:2021-01-01 00:00:00

  • Optimization methods for magnetic resonance imaging gradient waveform design.

    abstract::The development and implementation of novel MRI pulse sequences remains challenging and laborious. Gradient waveforms are typically designed using a combination of analytical and ad hoc methods to construct each gradient waveform axis independently. This strategy makes coding the pulse sequence complicated, in additio...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4308

    authors: Middione MJ,Loecher M,Moulin K,Ennis DB

    更新日期:2020-12-01 00:00:00

  • Fast multicomponent 3D-T1ρ relaxometry.

    abstract::NMR relaxometry can provide information about the relaxation of the magnetization in different tissues, increasing our understanding of molecular dynamics and biochemical composition in biological systems. In general, tissues have complex and heterogeneous structures composed of multiple pools. As a result, bulk magne...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4318

    authors: Zibetti MVW,Helou ES,Sharafi A,Regatte RR

    更新日期:2020-12-01 00:00:00

  • Physiological variation of the vertebral bone marrow water T2 relaxation time.

    abstract::The aim of this study was to investigate physiological variations of the water T2 relaxation time in vertebral bone marrow with respect to age, body mass index (BMI), sex and proton density fat fraction (PDFF) based on single-voxel magnetic resonance spectroscopy (MRS) at 3 T. Multi-TE single-voxel STEAM MRS data of a...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4439

    authors: Ruschke S,Syväri J,Dieckmeyer M,Junker D,Makowski MR,Baum T,Karampinos DC

    更新日期:2020-11-17 00:00:00

  • Investigating the regional effect of the chemical shift displacement artefact on the J-modulated lactate signal at ultra high-field.

    abstract::The present work aims to show the applicability of an analytical model for the optimisation of the STEAM sequence timing parameters for lactate detection at ultra high-field. The effects of the chemical shift displacement artefact on the J-modulated signal for a weakly-coupled spin system were considered in the three ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4440

    authors: Fernandes CC,Lanz B,Chen C,Morris PG,Salmon CG

    更新日期:2020-11-02 00:00:00

  • A formalism to investigate the optimal transmit efficiency in radiofrequency shimming.

    abstract::Transmit efficiency specifies the amplitude of the magnetic resonance excitation field produced over a region of interest with respect to the radiofrequency (RF) power deposited in the sample. This metric is highly important at ultra-high field magnetic resonance imaging (≥7 T), where excitation inhomogeneities and el...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4383

    authors: Georgakis IP,Polimeridis AG,Lattanzi R

    更新日期:2020-11-01 00:00:00

  • Myocardial T1 mapping using SMART1 Map and MOLLI mapping in asymptomatic patients with recent extracardiac sarcoidosis.

    abstract:INTRODUCTION:Sarcoidosis is a systemic granulomatous disease affecting in particular the respiratory tract. Cardiac magnetic resonance (CMR), including a measurement of T1 relaxation time, could potentially detect early stadia of sarcoidosis of the heart. The study aims to assess T1 mapping in the detection of early ca...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4388

    authors: Panovský R,Doubková M,Holeček T,Máchal J,Feitová V,Masárová L,Opatřil L,Mojica-Pisciotti ML,Kincl V

    更新日期:2020-11-01 00:00:00

  • Pulmonary pyruvate metabolism as an index of inflammation and injury in a rat model of acute respiratory distress syndrome.

    abstract::Increased pulmonary lactate production is correlated with severity of lung injury and outcome in acute respiratory distress syndrome (ARDS) patients. This study was conducted to investigate the relative contributions of inflammation and hypoxia to the lung's metabolic shift to glycolysis in an experimental animal mode...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4380

    authors: Pourfathi M,Xin Y,Rosalino M,Cereda M,Kadlecek S,Duncan I,Profka H,Hamedani H,Siddiqui S,Ruppert K,Chatterjee S,Rizi RR

    更新日期:2020-11-01 00:00:00

  • Rapid MR relaxometry using deep learning: An overview of current techniques and emerging trends.

    abstract::Quantitative mapping of MR tissue parameters such as the spin-lattice relaxation time (T1 ), the spin-spin relaxation time (T2 ), and the spin-lattice relaxation in the rotating frame (T1ρ ), referred to as MR relaxometry in general, has demonstrated improved assessment in a wide range of clinical applications. Compar...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4416

    authors: Feng L,Ma D,Liu F

    更新日期:2020-10-15 00:00:00

  • The influence of obesity on cerebral blood flow in young adults using arterial spin labeling MRI.

    abstract::Obesity causes damage to several organs, including the brain. Recent studies have been focusing on understanding the mechanisms through which obesity affects brain structure and function using neuroimaging techniques. A functional biomarker, such as cerebral blood flow (CBF), is a powerful tool that can be used to exp...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4375

    authors: Peng SL,Chen CM

    更新日期:2020-10-01 00:00:00

  • 3D free-breathing cardiac magnetic resonance fingerprinting.

    abstract:PURPOSE:To develop a novel respiratory motion compensated three-dimensional (3D) cardiac magnetic resonance fingerprinting (cMRF) approach for whole-heart myocardial T1 and T2 mapping from a free-breathing scan. METHODS:Two-dimensional (2D) cMRF has been recently proposed for simultaneous, co-registered T1 and T2 mapp...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4370

    authors: Cruz G,Jaubert O,Qi H,Bustin A,Milotta G,Schneider T,Koken P,Doneva M,Botnar RM,Prieto C

    更新日期:2020-10-01 00:00:00

  • A semi-LASER, single-voxel spectroscopic sequence with a minimal echo time of 20.1 ms in the human brain at 3 T.

    abstract::An optimized semi-LASER sequence that is capable of acquiring artefact-free data with an echo time (TE) of 20.1 ms on a standard clinical 3 T MR system was developed. Simulations were performed to determine the optimal TEs that minimize the expected Cramér-Rao lower bound (CRLB) as proxy for quantification accuracy of...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4324

    authors: Landheer K,Gajdošík M,Juchem C

    更新日期:2020-09-01 00:00:00

  • In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-13 C]alanine.

    abstract::d-amino acid oxidase (DAO) is a peroxisomal enzyme that catalyzes the oxidative deamination of several neutral and basic d-amino acids to their corresponding α-keto acids. In most mammalian species studied, high DAO activity is found in the kidney, liver, brain and polymorphonuclear leukocytes, and its main function i...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4303

    authors: Radaelli A,Gruetter R,Yoshihara HAI

    更新日期:2020-07-01 00:00:00

  • Longitudinal assessment of tissue properties and cardiac diffusion metrics of the ex vivo porcine heart at 7 T: Impact of continuous tissue fixation using formalin.

    abstract::In this study we aimed to assess the effects of continuous formalin fixation on diffusion and relaxation metrics of the ex vivo porcine heart at 7 T. Magnetic resonance imaging was performed on eight piglet hearts using a 7 T whole body system. Hearts were measured fresh within 3 hours of cardiac arrest followed by im...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4298

    authors: Lohr D,Terekhov M,Veit F,Schreiber LM

    更新日期:2020-07-01 00:00:00

  • Dynamic 2D and 3D mapping of hyperpolarized pyruvate to lactate conversion in vivo with efficient multi-echo balanced steady-state free precession at 3 T.

    abstract::The aim of this study was to acquire the transient MRI signal of hyperpolarized tracers and their metabolites efficiently, for which specialized imaging sequences are required. In this work, a multi-echo balanced steady-state free precession (me-bSSFP) sequence with Iterative Decomposition with Echo Asymmetry and Leas...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4291

    authors: Müller CA,Hundshammer C,Braeuer M,Skinner JG,Berner S,Leupold J,Düwel S,Nekolla SG,Månsson S,Hansen AE,von Elverfeldt D,Ardenkjaer-Larsen JH,Schilling F,Schwaiger M,Hennig J,Hövener JB

    更新日期:2020-06-01 00:00:00

  • Pattern recognition analysis of directional intravoxel incoherent motion MRI in ischemic rodent brains.

    abstract::This study aimed to demonstrate a reliable automatic segmentation method for independently separating reduced diffusion and decreased perfusion areas in ischemic stroke brains using constrained nonnegative matrix factorization (cNMF) pattern recognition in directional intravoxel incoherent motion MRI (IVIM-MRI). First...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4268

    authors: Jang M,Jin S,Kang M,Han S,Cho H

    更新日期:2020-05-01 00:00:00

  • T1ρ magnetic resonance fingerprinting.

    abstract::T1ρ relaxation imaging is a quantitative imaging technique that has been used to assess cartilage integrity, liver fibrosis, tumors, cardiac infarction, and Alzheimer's disease. T1 , T2 , and T1ρ relaxation time constants have each demonstrated different degrees of sensitivity to several markers of fibrosis and inflam...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4284

    authors: Wyatt CR,Barbara TM,Guimaraes AR

    更新日期:2020-05-01 00:00:00

  • Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1-13 C]pyruvate.

    abstract::Hyperpolarised [1-13 C]pyruvate MRI has shown promise in monitoring therapeutic efficacy in a number of cancers including glioma. In this study, we assessed the pyruvate response to the lentiviral suicide gene therapy of herpes simplex virus-1 thymidine kinase with the prodrug ganciclovir (HSV-TK/GCV) in C6 rat glioma...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4250

    authors: Nivajärvi R,Olsson V,Hyppönen V,Bowen S,Leinonen HM,Lesch HP,Ardenkjaer-Larsen JH,Gröhn OHJ,Ylä-Herttuala S,Kettunen MI

    更新日期:2020-04-01 00:00:00

  • Detection of myocardial medium-chain fatty acid oxidation and tricarboxylic acid cycle activity with hyperpolarized [1-13 C]octanoate.

    abstract::Under normal conditions, the heart mainly relies on fatty acid oxidation to meet its energy needs. Changes in myocardial fuel preference are noted in the diseased and failing heart. The magnetic resonance signal enhancement provided by spin hyperpolarization allows the metabolism of substrates labeled with carbon-13 t...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4243

    authors: Yoshihara HAI,Bastiaansen JAM,Karlsson M,Lerche MH,Comment A,Schwitter J

    更新日期:2020-03-01 00:00:00

  • Short- and long-term reproducibility of BOLD signal change induced by breath-holding at 1.5 and 3 T.

    abstract::Cerebrovascular reactivity (CVR) can give insight into the cerebrovascular function. CVR can be estimated by measuring a blood-oxygen-level-dependent (BOLD) response combined with breath-holding (BH). The reproducibility of this technique has been addressed and existing studies have focused on short-term reproducibili...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4195

    authors: Peng SL,Yang HC,Chen CM,Shih CT

    更新日期:2020-03-01 00:00:00

  • Structure or Exchange? On the Feasibility of Chemical Exchange Detection with Balanced Steady-State Free Precession in Tissue - An In Vitro Study.

    abstract::Balanced steady-state free precession imaging has recently been suggested for chemical exchange detection (bSSFPX). The objective of this work is to investigate the contributions of microstructural, chemical shift and chemical exchange effects to the asymmetry of the bSSFP profile at field strengths of 3 T and 9.4 T. ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4200

    authors: Heule R,Deshmane A,Zaiss M,Herz K,Ehses P,Scheffler K

    更新日期:2020-03-01 00:00:00

  • Noninvasive in situ proton MRS in muscle tissue and bone marrow as a novel approach to identify previous freezing in a completely thawed cadaver.

    abstract::The temporary or permanent storage of human bodies in freezers following a homicide is a documented method for criminal disposal of human corpses. In these cases, the detection of characteristics which indicate that a thawed cadaver or body part was previously frozen provides crucial information for forensic casework....

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4220

    authors: Gascho D,Richter H,Karampinos DC,Heimer J,Schaerli S,Thali MJ,Zoelch N

    更新日期:2020-02-01 00:00:00

  • Dynamic contrast-enhanced MRI model selection for predicting tumor aggressiveness in papillary thyroid cancers.

    abstract::The purpose of this study was to identify the optimal tracer kinetic model from T1 -weighted dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data and evaluate whether parameters estimated from the optimal model predict tumor aggressiveness determined from histopathology in patients with papillary thyroi...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4166

    authors: Paudyal R,Lu Y,Hatzoglou V,Moreira A,Stambuk HE,Oh JH,Cunanan KM,Aramburu Nunez D,Mazaheri Y,Gonen M,Ho A,Fagin JA,Wong RJ,Shaha A,Tuttle RM,Shukla-Dave A

    更新日期:2020-01-01 00:00:00

  • Evaluating the feasibility of creatine-weighted CEST MRI in human brain at 7 T using a Z-spectral fitting approach.

    abstract::The current study aims to evaluate the feasibility of creatine (Cr) chemical exchange saturation transfer (CEST)-weighted MRI at 7 T in the human brain by optimizing the saturation pulse parameters and computing contrast using a Z-spectral fitting approach. The Cr-weighted (Cr-w) CEST contrast was computed from phanto...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4176

    authors: Singh A,Debnath A,Cai K,Bagga P,Haris M,Hariharan H,Reddy R

    更新日期:2019-12-01 00:00:00

  • Estimation of cellular-interstitial water exchange in dynamic contrast enhanced MRI using two flip angles.

    abstract:PURPOSE:To investigate the feasibility of using multiple flip angles in dynamic contrast enhanced (DCE) MRI to reduce the uncertainty in estimation of intracellular water lifetime (τi ). METHODS:Numerical simulation studies were conducted to assess the uncertainty in estimation of τi using dynamic contrast enhanced MR...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4135

    authors: Zhang J,Kim SG

    更新日期:2019-11-01 00:00:00

  • Lactate infusion increases brain energy content during euglycemia but not hypoglycemia in healthy men.

    abstract::A special characteristic of the brain is the usage of lactate as alternative fuel instead of glucose to preserve its energy homeostasis. This physiological function is valid for sufficient cerebral glucose supply, as well as presumably during hypoglycemia, given that exogenous lactate infusion suppresses hormonal coun...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/nbm.4167

    authors: Richter J,Rabe D,Duysen K,Melchert UH,Oltmanns KM

    更新日期:2019-11-01 00:00:00

  • Assessing high-intensity focused ultrasound treatment of prostate cancer with hyperpolarized 13 C dual-agent imaging of metabolism and perfusion.

    abstract::The goal of the study was to establish early hyperpolarized (HP) 13 C MRI metabolic and perfusion changes that predict effective high-intensity focused ultrasound (HIFU) ablation and lead to improved adjuvant treatment of partially treated regions. To accomplish this a combined HP dual-agent (13 C pyruvate and 13 C ur...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3962

    authors: Lee JE,Diederich CJ,Bok R,Sriram R,Santos RD,Noworolski SM,Salgaonkar VA,Adams MS,Vigneron DB,Kurhanewicz J

    更新日期:2019-10-01 00:00:00

  • Mapping the human brainstem: Brain nuclei and fiber tracts at 3 T and 7 T.

    abstract::Structural high-resolution imaging of the brainstem can be of high importance in clinical practice. However, ultra-high field magnetic resonance imaging (MRI) is still restricted in use due to limited availability. Therefore, quantitative MRI techniques (quantitative susceptibility mapping [QSM], relaxation measuremen...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4118

    authors: Straub S,Knowles BR,Flassbeck S,Steiger R,Ladd ME,Gizewski ER

    更新日期:2019-09-01 00:00:00

  • The role of iron and myelin in orientation dependent R2 * of white matter.

    abstract::Brain myelin and iron content are important parameters in neurodegenerative diseases such as multiple sclerosis (MS). Both myelin and iron content influence the brain's R2* relaxation rate. However, their quantification based on R2* maps requires a realistic tissue model that can be fitted to the measured data. In str...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4092

    authors: Kor D,Birkl C,Ropele S,Doucette J,Xu T,Wiggermann V,Hernández-Torres E,Hametner S,Rauscher A

    更新日期:2019-07-01 00:00:00

  • Magnetic resonance elastography of skeletal muscle deep tissue injury.

    abstract::The current state-of-the-art diagnosis method for deep tissue injury in muscle, a subcategory of pressure ulcers, is palpation. It is recognized that deep tissue injury is frequently preceded by altered biomechanical properties. A quantitative understanding of the changes in biomechanical properties preceding and duri...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4087

    authors: Nelissen JL,Sinkus R,Nicolay K,Nederveen AJ,Oomens CWJ,Strijkers GJ

    更新日期:2019-06-01 00:00:00

  • A review of diffusion MRI of typical white matter development from early childhood to young adulthood.

    abstract::Understanding typical, healthy brain development provides a baseline from which to detect and characterize brain anomalies associated with various neurological or psychiatric disorders and diseases. Diffusion MRI is well suited to study white matter development, as it can virtually extract individual tracts and yield ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审

    doi:10.1002/nbm.3778

    authors: Lebel C,Treit S,Beaulieu C

    更新日期:2019-04-01 00:00:00

  • Glucagon infusion alters the hyperpolarized 13 C-urea renal hemodynamic signature.

    abstract::Renal urea handling is central to the urine concentrating mechanism, and as such the ability to image urea transport in the kidney is an important potential imaging biomarker for renal functional assessment. Glucagon levels associated with changes in dietary protein intake have been shown to influence renal urea handl...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4028

    authors: Qi H,Mariager CØ,Nielsen PM,Schroeder M,Lindhardt J,Nørregaard R,Klein JD,Sands JM,Laustsen C

    更新日期:2019-01-01 00:00:00

  • High-resolution echo-planar spectroscopic imaging at ultra-high field.

    abstract::MR spectroscopic imaging (MRSI) at ultra-high field (≥7 T) benefits from improved sensitivity that allows the detection of low-concentration metabolites in the brain. However, optimized acquisition techniques are required to overcome inherent limitations of MRSI at ultra-high field. This work describes an optimized me...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3950

    authors: Coello E,Noeske R,Burns BL,Gordon JW,Jakary A,Menze B,Haase A,Larson PEZ,Li Y,Schulte RF

    更新日期:2018-11-01 00:00:00

  • Spring-damper equivalents of the fractional, poroelastic, and poroviscoelastic models for elastography.

    abstract::In MR elastography, it is common to use an elastic model for the tissue's response in order to interpret the results properly. More complex models, such as viscoelastic, fractional viscoelastic, poroelastic, or poroviscoelastic ones, are also used. These models appear at first sight to be very different, but here it i...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3854

    authors: Holm S

    更新日期:2018-10-01 00:00:00

  • Intragastric balloon therapy leads to normalization of brain magnetic resonance spectroscopic markers of diabetes in morbidly obese patients.

    abstract::Elevated brain myo-inositol (m-Ins) concentration (a putative marker of neuroinflammation) has been reported in patients suffering from type 2 diabetes mellitus (T2DM). Obesity alone and T2DM have been found to be associated with a lower concentration of N-acetyloaspartate and N-acetylaspartylglutamate (tNAA, a marker...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3957

    authors: Gazdzinski SP,Gaździńska AP,Orzeł J,Redlisz-Redlicki G,Pietruszka M,Mojkowska A,Pacho RA,Wylezol M

    更新日期:2018-09-01 00:00:00

  • Dynamic multivoxel-localized 31 P MRS during plantar flexion exercise with variable knee angle.

    abstract::Exercise studies investigating the metabolic response of calf muscles using 31 P MRS are usually performed with a single knee angle. However, during natural movement, the distribution of workload between the main contributors to force, gastrocnemius and soleus is influenced by the knee angle. Hence, it is of interest ...

    journal_title:NMR in biomedicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/nbm.3905

    authors: Niess F,Fiedler GB,Schmid AI,Laistler E,Frass-Kriegl R,Wolzt M,Moser E,Meyerspeer M

    更新日期:2018-06-01 00:00:00

  • Neonatal hyperglycemia alters the neurochemical profile, dendritic arborization and gene expression in the developing rat hippocampus.

    abstract::Hyperglycemia (blood glucose concentration >150 mg/dL) is common in extremely low gestational age newborns (ELGANs; birth at <28 week gestation). Hyperglycemia increases the risk of brain injury in the neonatal period. The long-term effects are not well understood. In adult rats, hyperglycemia alters hippocampal energ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3910

    authors: Rao R,Nashawaty M,Fatima S,Ennis K,Tkac I

    更新日期:2018-05-01 00:00:00

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