Acquisition of ³He ventilation images, ADC, T₂* and B₁ maps in a single scan with compressed sensing.

abstract：:The parameters that characterize the intricate water diffusion in tumors may serve to reveal their distinct pathology. Specifically, the application of diffusion magnetic resonance imaging (MRI) can aid in characterizing breast cancer, as well as monitoring response to therapy. We present here a non-invasive, quantita...

journal_title：NMR in biomedicine

authors： Paran Y,Bendel P,Margalit R,Degani H

更新日期：2004-06-01 00:00:00

abstract：:The purpose of this work was to assess the reproducibility of percentage of ventilated lung volume (PV) measured from hyperpolarized (HP) (3)He and (1)H anatomical images acquired in the same breath-hold when compared with PV measured from (3)He and (1)H images from separate breath-holds. Volumetric (3)He ventilation ...

journal_title：NMR in biomedicine

authors： Horn FC,Tahir BA,Stewart NJ,Collier GJ,Norquay G,Leung G,Ireland RH,Parra-Robles J,Marshall H,Wild JM

更新日期：2014-12-01 00:00:00

abstract：:Cerebral ischemia provokes tissue damage by two major patho-physiological mechanisms. Direct cell necrosis is induced by diminished access of neurons and glia to essential nutrients such as glucose and oxygen leading to energy failure. A second factor of cellular loss is related to the activation of immune-competent c...

journal_title：NMR in biomedicine

authors： Rausch M,Baumann D,Neubacher U,Rudin M

更新日期：2002-06-01 00:00:00

abstract：:Signal of lung parenchymal tissue from the living rat and mouse lung was detected at 4.7 T with a good signal-to-noise ratio and motion-suppressed artifacts using a short TE gradient-echo sequence. Neither cardiac nor respiratory gating were applied, and animals respired freely during data collection. Mean T(2)* relax...

journal_title：NMR in biomedicine

authors： Beckmann N,Tigani B,Mazzoni L,Fozard JR

更新日期：2001-08-01 00:00:00

abstract：:This paper compares two spectral processing methods for obtaining quantitative measures from in vivo prostate spectra, evaluates their effectiveness, and discusses the necessary modifications for accurate results. A frequency domain analysis (FDA) method based on peak integration was compared with a time domain fittin...

journal_title：NMR in biomedicine

authors： Pels P,Ozturk-Isik E,Swanson MG,Vanhamme L,Kurhanewicz J,Nelson SJ,Van Huffel S

更新日期：2006-04-01 00:00:00

abstract：:The development and implementation of novel MRI pulse sequences remains challenging and laborious. Gradient waveforms are typically designed using a combination of analytical and ad hoc methods to construct each gradient waveform axis independently. This strategy makes coding the pulse sequence complicated, in additio...

journal_title：NMR in biomedicine

authors： Middione MJ,Loecher M,Moulin K,Ennis DB

更新日期：2020-12-01 00:00:00

abstract：:Management of brain tumours in children would benefit from improved non-invasive diagnosis, characterisation and prognostic biomarkers. Metabolite profiles derived from in-vivo MRS have been shown to provide such information. Studies indicate that using optimum a priori information on metabolite contents in the constr...

journal_title：NMR in biomedicine

authors： Davies NP,Wilson M,Natarajan K,Sun Y,MacPherson L,Brundler MA,Arvanitis TN,Grundy RG,Peet AC

更新日期：2010-01-01 00:00:00

abstract：:The transverse relaxation rates R2 and R2* were measured at 3 T in the substantia nigra of the midbrain of adult normal human controls. The relaxation rate arising from magnetic inhomogeneities, R2', was calculated from the relationship R2* = R2 + R2'. No significant differences were found for any parameters between l...

journal_title：NMR in biomedicine

authors： Helpern JA,Ordidge RJ,Gorell JM,Deniau JC,Welch KM

更新日期：1995-02-01 00:00:00

abstract：:The purpose of the present study was to characterize the metabolic profile of the visual cortex in streptozotocin-induced Type 1 diabetic rats by means of in vivo proton MRS. Several metabolite concentration ratios in the visual cortex were calculated. In addition, postmortem histologic analyses for retinal ganglion c...

journal_title：NMR in biomedicine

authors： Li S,Wang X,Yang J,Lei H,Wang X,Xiang Y

更新日期：2017-11-01 00:00:00

abstract：:This study investigated the association between the total choline (tCho) concentration and the clinical characteristics and biomarker status of breast cancer. Sixty-two patients with breast cancer, 1.5  cm or larger in size on MR images, were studied. The tCho concentration was correlated with the MRI features, contra...

journal_title：NMR in biomedicine

authors： Chen JH,Mehta RS,Baek HM,Nie K,Liu H,Lin MQ,Yu HJ,Nalcioglu O,Su MY

更新日期：2011-04-01 00:00:00

abstract：:Resolution enhancement for glutamate (Glu), glutamine (Gln) and glutathione (GSH) in the human brain by TE-optimized point-resolved spectroscopy (PRESS) at 7 T is reported. Sub-TE dependences of the multiplets of Glu, Gln, GSH, γ-aminobutyric acid (GABA) and N-acetylaspartate (NAA) at 2.2-2.6 ppm were investigated wit...

journal_title：NMR in biomedicine

authors： Choi C,Dimitrov IE,Douglas D,Patel A,Kaiser LG,Amezcua CA,Maher EA

更新日期：2010-11-01 00:00:00

abstract：:The elimination of so-called background fields is an essential step in phase MRI and quantitative susceptibility mapping (QSM). Background fields, which are caused by sources outside the region of interest (ROI), are often one to two orders of magnitude stronger than tissue-related field variations from within the ROI...

journal_title：NMR in biomedicine

authors： Schweser F,Robinson SD,de Rochefort L,Li W,Bredies K

更新日期：2017-04-01 00:00:00

abstract：:The main aim of this study was to employ high-resolution MRI to investigate the spatiotemporal development of pathological features associated with contusive spinal cord injury (SCI) in mice. Experimental mice were subjected to either sham surgery or moderate contusive SCI. A 16.4-T small-animal MR system was employed...

journal_title：NMR in biomedicine

authors： Blomster LV,Cowin GJ,Kurniawan ND,Ruitenberg MJ

更新日期：2013-02-01 00:00:00

abstract：:In this study we aimed to assess the effects of continuous formalin fixation on diffusion and relaxation metrics of the ex vivo porcine heart at 7 T. Magnetic resonance imaging was performed on eight piglet hearts using a 7 T whole body system. Hearts were measured fresh within 3 hours of cardiac arrest followed by im...

journal_title：NMR in biomedicine

authors： Lohr D,Terekhov M,Veit F,Schreiber LM

更新日期：2020-07-01 00:00:00

abstract：:Following the development of parallel imaging, parallel transmission describes the use of multiple RF transmit coils. Parallel transmission can be applied to improve RF excitation, in particular, multidimensional, spatially selective RF excitation. For instance, parallel transmission is able to shorten spatially selec...

journal_title：NMR in biomedicine

authors： Katscher U,Börnert P

更新日期：2006-05-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) in pregnancy is commonly undertaken in the left lateral tilt (LLT) position to prevent inferior vena cava (IVC) compression and supine hypotensive events, although this may be suboptimal for image quality. The supine position may also have an adverse effect on fetal well-being. The spi...

journal_title：NMR in biomedicine

authors： Hughes EJ,Price AN,McCabe L,Hiscocks S,Waite L,Green E,Hutter J,Pegoretti K,Cordero-Grande L,Edwards DA,Hajnal JV,Rutherford MA

更新日期：2021-01-21 00:00:00

abstract：:Citicoline supplementation has been used to ameliorate memory disturbances in older people and those with Alzheimer's disease. This study used MRS to characterize the effects of citicoline on high-energy phosphate metabolites and constituents of membrane synthesis in the frontal lobe. Phosphorus ((31)P) metabolite dat...

journal_title：NMR in biomedicine

authors： Silveri MM,Dikan J,Ross AJ,Jensen JE,Kamiya T,Kawada Y,Renshaw PF,Yurgelun-Todd DA

更新日期：2008-11-01 00:00:00

abstract：:Phosphorus-31 magnetic resonance spectroscopy ((31)P-MRS) has gained much interest in schizophrenia research in recent years since it allows the non-invasive measurement of high-energy phosphates and phospholipids in vivo. However, until now only differences in metabolite concentrations between certain brain areas of ...

journal_title：NMR in biomedicine

authors： Riehemann S,Volz HP,Wenda B,Hübner G,Rössger G,Rzanny R,Sauer H

更新日期：1999-12-01 00:00:00

abstract：:With a fixed time to acquire a magnetic resonance (MR) image, time can be spent to acquire better spatial resolution with decrease in signal-to-noise ratio (SNR) or decreased resolution with increase in SNR. This resolution/SNR tradeoff at fixed time has been investigated by a visual rater study using images of ex viv...

journal_title：NMR in biomedicine

authors： Kale SC,Chen XJ,Henkelman RM

更新日期：2009-06-01 00:00:00

abstract：:Central obesity is the hallmark of a number of non-inheritable disorders. The advent of imaging techniques such as MRI has allowed for a fast and accurate assessment of body fat content and distribution. However, image analysis continues to be one of the major obstacles to the use of MRI in large-scale studies. In thi...

journal_title：NMR in biomedicine

authors： Borga M,Thomas EL,Romu T,Rosander J,Fitzpatrick J,Dahlqvist Leinhard O,Bell JD

更新日期：2015-12-01 00:00:00

abstract：:The potential use of 13C multilabeled substrates has been studied in biological applications using in vivo and in vitro proton and 13C NMR spectroscopy. In 13C NMR spectroscopy, multilabeled compounds allow the simultaneous observation of several nuclei or increase distinctly the signal to noise ratio due to a higher ...

journal_title：NMR in biomedicine

authors： Künnecke B,Cerdan S

更新日期：1989-12-01 00:00:00

abstract：:Development and evaluation of new anticancer drugs are expedited when minimally invasive biomarkers of pharmacokinetic and pharmacodynamic behaviour are available. Gene-directed enzyme prodrug therapy (GDEPT) is a suicide gene therapy in which the anticancer drug is activated in the tumor by an exogenous enzyme previo...

journal_title：NMR in biomedicine

authors： Mancini L,Davies L,Friedlos F,Falck-Miniotis M,Dzik-Jurasz AS,Springer CJ,Leach MO,Payne GS

更新日期：2009-06-01 00:00:00

abstract：:Electric properties tomography (EPT) derives the patient's electric properties, i.e. conductivity and permittivity, using standard magnetic resonance (MR) systems and standard MR sequences. Thus, EPT does not apply externally mounted electrodes, currents or radiofrequency (RF) probes, as is the case in competing techn...

journal_title：NMR in biomedicine

authors： Katscher U,van den Berg CAT

更新日期：2017-08-01 00:00:00

abstract：:A current limitation of MR spectroscopic imaging of multiple skeletal muscles is prolonged scan duration. A significant reduction in the total scan duration using the echo-planar correlated spectroscopic imaging (EP-COSI) sequence was accomplished using two bipolar readout trains with different phase-encoded echoes fo...

journal_title：NMR in biomedicine

authors： Furuyama JK,Nagarajan R,Roberts CK,Lee CC,Hahn TJ,Thomas MA

更新日期：2014-10-01 00:00:00

abstract：:The dependence of apparent diffusion coefficients (ADCs) of molecules in biological tissues on an acquisition-specific timescale is a powerful mechanism for studying tissue microstructure. Unlike water, metabolites are confined mainly to intracellular compartments, thus providing higher specificity to tissue microstru...

journal_title：NMR in biomedicine

authors： Branzoli F,Ercan E,Webb A,Ronen I

更新日期：2014-05-01 00:00:00

abstract：:In vitro (1)H MRS of human bile has shown potential in the diagnosis of various hepatopancreatobiliary (HPB) diseases. Previously, in vivo (1)H MRS of human bile in gallbladder using a 1.5 T scanner demonstrated the possibility of quantification of choline-containing phospholipids (chol-PLs). However, other lipid comp...

journal_title：NMR in biomedicine

authors： Mohajeri S,Ijare OB,Bezabeh T,King SB,Thomas MA,Minuk G,Lipschitz J,Kirkpatrick I,Smith M,Smith IC

更新日期：2014-10-01 00:00:00

abstract：:Glucose metabolism in control and estrogen stimulated rat uteri was investigated using 13C NMR spectroscopy. By employing an NMR adapted perifusion system, and developing protocols and methods based on the application of [1-13C]glucose labeling, it was possible to measure, with a temporal resolution of 10 min, the kin...

journal_title：NMR in biomedicine

authors： Shinkarenko L,Kaye AM,Degani H

更新日期：1994-08-01 00:00:00

abstract：:In this study, metabolic changes in the 79A/C3H, ME7/VM, ME7/C3H, 87V/VM and 22A/SV scrapie mouse models were investigated during the clinical phase of the disease, using in vitro proton nuclear magnetic resonance spectroscopy. N-acetyl-aspartate was found to be significantly reduced in infected mice of the ME7/ C3H (...

journal_title：NMR in biomedicine

authors： Chung YL,Williams A,Chong A,Hope J,Williams SC,Bell JD

更新日期：1996-12-01 00:00:00

abstract：:The goal of the study was to establish early hyperpolarized (HP) 13 C MRI metabolic and perfusion changes that predict effective high-intensity focused ultrasound (HIFU) ablation and lead to improved adjuvant treatment of partially treated regions. To accomplish this a combined HP dual-agent (13 C pyruvate and 13 C ur...

journal_title：NMR in biomedicine

authors： Lee JE,Diederich CJ,Bok R,Sriram R,Santos RD,Noworolski SM,Salgaonkar VA,Adams MS,Vigneron DB,Kurhanewicz J

更新日期：2019-10-01 00:00:00

abstract：:Quantitative analysis of extracts from two Ehrlich ascites tumour cell lines (Lettre cells) by 19F NMR in vitro demonstrated that one Lettre cell line (designated LLM) metabolized 30-50% less 5-fluorouracil to 5-fluoronucleotides when compared to the other cell line (designated LHM). HPLC analysis of these cellular ex...

journal_title：NMR in biomedicine

authors： McSheehy PM,Maxwell RJ,Griffiths JR

更新日期：1991-12-01 00:00:00