Identification of diffuse and focal brain lesions by clinical magnetic resonance spectroscopy.

Abstract:

:The purpose of this paper is to facilitate the comparison of magnetic resonance (MR) spectra acquired from unknown brain lesions with published spectra in order to help identify unknown lesions in clinical settings. The paper includes lists of references for published MR spectra of various brain diseases, including pyogenic abscesses, encephalitis (herpes simplex, Rasmussen's and subacute sclerosing panencephalitis), neurocysticercosis, tuberculoma, cysts (arachnoid, epidermoid and hydatid), acute disseminated encephalomyelitis (ADEM), adrenoleukodystrophy (ALD), Alexander disease, Canavan's disease, Krabbe disease (globoid cell leukodystrophy), Leigh's disease, megalencephalic leukoencephalopathy with cysts, metachromatic leukodystrophy (MLD), Pelizaeus-Merzbacher disease, Zellweger syndrome, HIV-associated lesions [cryptococcus, lymphoma, toxoplasmosis and progressive multifocal leukoencephalopathy (PML)], hydrocephalus and tuberous sclerosis. Each list includes information on the echo time(s) (TE) of the published spectra, whether a control spectrum is shown, whether the corresponding image and voxel position are shown and the patient ages if known. The references are listed in the approximate order of usefulness, based on spectral quality, number of spectra, range of echo times and whether the voxel positions are shown. Spectra of Zellweger syndrome, cryptococcal infection, toxoplasmosis and lymphoma are included, along with a spectrum showing propanediol (propylene glycol).

journal_name

NMR Biomed

journal_title

NMR in biomedicine

authors

Kingsley PB,Shah TC,Woldenberg R

doi

10.1002/nbm.1039

subject

Has Abstract

pub_date

2006-06-01 00:00:00

pages

435-62

issue

4

eissn

0952-3480

issn

1099-1492

journal_volume

19

pub_type

杂志文章,评审
  • 13C NMR spectroscopic analysis of phospholipid metabolism in adrenal chromaffin cells.

    abstract::Phosphatidylcholine (PC) metabolism in bovine adrenal chromaffin cells has been studied in vivo with 100 MHz 13C NMR spectroscopy. The incorporation of 13[CH3]choline was examined in cells embedded in 1% agarose strands and perfused at 37 degrees C. The pattern of 13C NMR spectroscopy. The incorporation of [13CH3]chol...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1940040304

    authors: Rivera CJ,Plishker GA,Morrisett JD,Moore J,Percy AK

    更新日期:1991-06-01 00:00:00

  • Diffusion-weighted MRI measurements on stroke patients reveal water-exchange mechanisms in sub-acute ischaemic lesions.

    abstract::The aim of this study was to investigate the diffusion time dependence of signal-versus-b curves obtained from diffusion-weighted magnetic resonance imaging (DW-MRI) of sub-acute ischaemic lesions in stroke patients. In this case series study, 16 patients with sub-acute ischaemic stroke were examined with DW-MRI using...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1376

    authors: Lätt J,Nilsson M,van Westen D,Wirestam R,Ståhlberg F,Brockstedt S

    更新日期:2009-07-01 00:00:00

  • Lactate efflux and the neuroenergetic basis of brain function.

    abstract::In the unstimulated brain energy is primarily supplied by the oxidation of glucose. However the oxygen-to-glucose index (OGI), which is the ratio of metabolic rates of oxygen to glucose, CMR(O2)/CMR(glc), diverges from the theoretical value of 6 as activity is increased. In vivo measurements of brain lactate show its ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.741

    authors: Shulman RG,Hyder F,Rothman DL

    更新日期:2001-11-01 00:00:00

  • Inferring microstructural features and the physiological state of tissues from diffusion-weighted images.

    abstract::We review several methods that have been developed to infer microstructural and physiological information about isotropic and anisotropic tissues from diffusion weighted images (DWIs). These include Diffusion Imaging (DI), Diffusion Tensor Imaging (DTI), isotropically weighted imaging, and q-space imaging. Just as DI ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审

    doi:10.1002/nbm.1940080707

    authors: Basser PJ

    更新日期:1995-11-01 00:00:00

  • 1 H NMRS of carnosine combined with 31 P NMRS to better characterize skeletal muscle pH dysregulation in Duchenne muscular dystrophy.

    abstract::In recent years, quantitative nuclear magnetic resonance imaging and spectroscopy (NMRI and NMRS) have been used more systematically as outcome measures in natural history and clinical trial studies for Duchenne muscular dystrophy (DMD). Whereas most of these studies have emphasized the evaluation of the fat fraction ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3839

    authors: Reyngoudt H,Turk S,Carlier PG

    更新日期:2018-01-01 00:00:00

  • Temporal scaling properties and spatial synchronization of spontaneous blood oxygenation level-dependent (BOLD) signal fluctuations in rat sensorimotor network at different levels of isoflurane anesthesia.

    abstract::Spontaneous fluctuations in the blood oxygenation level-dependent (BOLD) MRI signal during the resting state are increasingly being studied in healthy and diseased brain in humans and animal models. Yet, the relationship between functional brain status and the characteristics of spontaneous BOLD fluctuations remains p...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1556

    authors: Wang K,van Meer MP,van der Marel K,van der Toorn A,Xu L,Liu Y,Viergever MA,Jiang T,Dijkhuizen RM

    更新日期:2011-01-01 00:00:00

  • In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO.

    abstract::Cerebral ischemia provokes tissue damage by two major patho-physiological mechanisms. Direct cell necrosis is induced by diminished access of neurons and glia to essential nutrients such as glucose and oxygen leading to energy failure. A second factor of cellular loss is related to the activation of immune-competent c...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.770

    authors: Rausch M,Baumann D,Neubacher U,Rudin M

    更新日期:2002-06-01 00:00:00

  • Dynamic nuclear polarization polarizer for sterile use intent.

    abstract::A novel polarizer based on the dissolution-dynamic nuclear polarization (DNP) method has been designed, built and tested. The polarizer differs from those previously described by being designed with sterile use intent and being compatible with clinical use. The main features are: (1) an integral, disposable fluid path...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1682

    authors: Ardenkjaer-Larsen JH,Leach AM,Clarke N,Urbahn J,Anderson D,Skloss TW

    更新日期:2011-10-01 00:00:00

  • In vivo characterization of fatty acids in human adipose tissue using natural abundance 1H decoupled 13C MRS at 1.5 T: clinical applications to dietary therapy.

    abstract::Natural abundance proton-decoupled (13)C magnetic resonance spectroscopy was used to establish the in vivo lipid composition of normal adipose tissue and the corresponding effects of altered lipid diets. Experiments were performed on a standard 1.5 T clinical MR scanner using a double-tuned (1)H-(13)C coil. Peaks from...

    journal_title:NMR in biomedicine

    pub_type: 临床试验,杂志文章

    doi:10.1002/nbm.824

    authors: Hwang JH,Bluml S,Leaf A,Ross BD

    更新日期:2003-05-01 00:00:00

  • Transrectal ultrasound-guided biopsy of prostate voxels identified as suspicious of malignancy on three-dimensional (1)H MR spectroscopic imaging in patients with abnormal digital rectal examination or raised prostate specific antigen level of 4-10 ng/ml.

    abstract::Results of the evaluation of transrectal ultrasound (TRUS) guided needle biopsy of voxels identified as suspicious of malignancy on magnetic resonance spectroscopic imaging (MRSI) in a large cohort of men (n = 83) with abnormal digital rectal examination (DRE) [prostate specific antigen (PSA) 0-4 ng/ml] or PSA less th...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1083

    authors: Kumar V,Jagannathan NR,Kumar R,Thulkar S,Gupta SD,Hemal AK,Gupta NP

    更新日期:2007-02-01 00:00:00

  • Accelerated high-frame-rate mouse heart cine-MRI using compressed sensing reconstruction.

    abstract::We introduce a new protocol to obtain very high-frame-rate cinematographic (Cine) MRI movies of the beating mouse heart within a reasonable measurement time. The method is based on a self-gated accelerated fast low-angle shot (FLASH) acquisition and compressed sensing reconstruction. Key to our approach is that we exp...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.2883

    authors: Motaal AG,Coolen BF,Abdurrachim D,Castro RM,Prompers JJ,Florack LM,Nicolay K,Strijkers GJ

    更新日期:2013-04-01 00:00:00

  • Structure or Exchange? On the Feasibility of Chemical Exchange Detection with Balanced Steady-State Free Precession in Tissue - An In Vitro Study.

    abstract::Balanced steady-state free precession imaging has recently been suggested for chemical exchange detection (bSSFPX). The objective of this work is to investigate the contributions of microstructural, chemical shift and chemical exchange effects to the asymmetry of the bSSFP profile at field strengths of 3 T and 9.4 T. ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4200

    authors: Heule R,Deshmane A,Zaiss M,Herz K,Ehses P,Scheffler K

    更新日期:2020-03-01 00:00:00

  • Single echo acquisition MRI using RF encoding.

    abstract::Encoding of spatial information in magnetic resonance imaging is conventionally accomplished by using magnetic field gradients. During gradient encoding, the position in k-space is determined by a time-integral of the gradient field, resulting in a limitation in imaging speed due to either gradient power or secondary ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1399

    authors: Wright SM,McDougall MP

    更新日期:2009-11-01 00:00:00

  • Measurement of creatine kinase reaction rate in human brain using magnetization transfer image-selected in vivo spectroscopy (MT-ISIS) and a volume ³¹P/¹H radiofrequency coil in a clinical 3-T MRI system.

    abstract::High-energy phosphate metabolism, which allows the synthesis and regeneration of adenosine triphosphate (ATP), is a vital process for neuronal survival and activity. In particular, creatine kinase (CK) serves as an energy reservoir for the rapid buffering of ATP levels. Altered CK enzyme activity, reflecting compromis...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1636

    authors: Jeong EK,Sung YH,Kim SE,Zuo C,Shi X,Mellon EA,Renshaw PF

    更新日期:2011-08-01 00:00:00

  • Phosphorus MR spectroscopy in the treatment of human extremity sarcomas.

    abstract::The application of 31P MR spectroscopy in the characterization and treatment of malignant human extremity tumors is reviewed and placed in the perspective of results obtained in murine sarcomas. Despite the now widespread acquisition of gradient localized spectral maps, the low spatial resolution that can be achieved ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1099-1492(1998110)11:7<341::aid-nbm5

    authors: Sijens PE

    更新日期:1998-11-01 00:00:00

  • Analysis of parametric histogram from dynamic contrast-enhanced MRI: application in evaluating brain tumor response to radiotherapy.

    abstract::Dynamic contrast-enhanced MRI (DCE MRI) has been used to study tumor response to treatment for many years. In this study, the modified full width at half-maximum (mFWHM), calculated from the wash-in slope histogram, is proposed as a parameter for the evaluation of changes in tumor heterogeneity which respond to radiot...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.2882

    authors: Peng SL,Chen CF,Liu HL,Lui CC,Huang YJ,Lee TH,Chang CC,Wang FN

    更新日期:2013-04-01 00:00:00

  • Time-domain semi-parametric estimation based on a metabolite basis set.

    abstract::A novel and fast time-domain quantitation algorithm--quantitation based on semi-parametric quantum estimation (QUEST)--invoking optimal prior knowledge is proposed and tested. This nonlinear least-squares algorithm fits a time-domain model function, made up from a basis set of quantum-mechanically simulated whole-meta...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.895

    authors: Ratiney H,Sdika M,Coenradie Y,Cavassila S,van Ormondt D,Graveron-Demilly D

    更新日期:2005-02-01 00:00:00

  • Novel corrective equations for complete estimation of human tissue lipids after their partial destruction by perchloric acid pre-treatment: high-resolution (1)H-NMR-based study.

    abstract::Owing to the small quantity of tissue available in human biopsy specimens, aqueous and lipid components often have to be determined in the same tissue sample. Perchloric acid (PCA) used for the extraction of aqueous metabolites has a deleterious effect on lipid components; the severity of the damage is not known. In t...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1159

    authors: Srivastava NK,Pradhan S,Mittal B,Kumar R,Pandey CM,Gowda GA

    更新日期:2008-02-01 00:00:00

  • Detection of endogenous iron deposits in the injured mouse spinal cord through high-resolution ex vivo and in vivo MRI.

    abstract::The main aim of this study was to employ high-resolution MRI to investigate the spatiotemporal development of pathological features associated with contusive spinal cord injury (SCI) in mice. Experimental mice were subjected to either sham surgery or moderate contusive SCI. A 16.4-T small-animal MR system was employed...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.2829

    authors: Blomster LV,Cowin GJ,Kurniawan ND,Ruitenberg MJ

    更新日期:2013-02-01 00:00:00

  • Cerebral blood volume MRI with intravascular superparamagnetic iron oxide nanoparticles.

    abstract::The cerebral blood volume (CBV) is a crucial physiological indicator of tissue viability and vascular reactivity. Thus, noninvasive CBV mapping has been of great interest. For this, ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles, including monocrystalline iron oxide nanoparticles, can be used as long-ha...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审

    doi:10.1002/nbm.2885

    authors: Kim SG,Harel N,Jin T,Kim T,Lee P,Zhao F

    更新日期:2013-08-01 00:00:00

  • In vivo detection of d-amino acid oxidase with hyperpolarized d-[1-13 C]alanine.

    abstract::d-amino acid oxidase (DAO) is a peroxisomal enzyme that catalyzes the oxidative deamination of several neutral and basic d-amino acids to their corresponding α-keto acids. In most mammalian species studied, high DAO activity is found in the kidney, liver, brain and polymorphonuclear leukocytes, and its main function i...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4303

    authors: Radaelli A,Gruetter R,Yoshihara HAI

    更新日期:2020-07-01 00:00:00

  • A method to extract three-dimensional objects from three-dimensional NMR image data.

    abstract::A method to extract shapes of bubble polyhedra from three-dimensional nuclear magnetic resonance image data of foam has been developed. The method consists of four steps: first, to compute series of maximum intensity projection images from the three-dimensional NMR image data of foam to visualize the network structure...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-1492(199701)10:1<13::aid-nbm443

    authors: Kashiwagi K,Kose K

    更新日期:1997-01-01 00:00:00

  • NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold.

    abstract::One of the major goals of hyperpolarized-gas MR imaging has been to obtain (129)Xe dissolved-phase images in humans. Since the dissolved-phase signal is much weaker than the gas-phase signal, highly optimized MR pulse sequences are required to obtain adequate images during a single breath-hold. In particular, a solid ...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/1099-1492(200006)13:4<220::aid-nbm638>3.0.

    authors: Ruppert K,Brookeman JR,Hagspiel KD,Driehuys B,Mugler JP 3rd

    更新日期:2000-06-01 00:00:00

  • Gadolinium and dysprosium chelates of DTPA-amide-dextran: synthesis, 1H NMR relaxivity, and induced 23Na NMR shift.

    abstract::In this study the conjugated macromolecular ligand, diethylenetriaminepentaacetic acid (DTPA)-amide-dextran, was synthesized by attaching DTPA to the dextran macromolecule (M(r) approximately 6000) by a covalent amide bond. Subsequently, DTPA-amide-dextran was complexed with either of the two lanthanide metal ions dys...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1940080404

    authors: Chu WJ,Elgavish GA

    更新日期:1995-06-01 00:00:00

  • Electric properties tomography: Biochemical, physical and technical background, evaluation and clinical applications.

    abstract::Electric properties tomography (EPT) derives the patient's electric properties, i.e. conductivity and permittivity, using standard magnetic resonance (MR) systems and standard MR sequences. Thus, EPT does not apply externally mounted electrodes, currents or radiofrequency (RF) probes, as is the case in competing techn...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章,评审

    doi:10.1002/nbm.3729

    authors: Katscher U,van den Berg CAT

    更新日期:2017-08-01 00:00:00

  • Assessment of cortical damage in early multiple sclerosis with quantitative T2 relaxometry.

    abstract::T2 relaxation time is a quantitative MRI in vivo surrogate of cerebral tissue damage in multiple sclerosis (MS) patients. Cortical T2 prolongation is a known feature in later disease stages, but has not been demonstrated in the cortical normal appearing gray matter (NAGM) in early MS. This study centers on the quantit...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3486

    authors: Gracien RM,Reitz SC,Hof SM,Fleischer V,Zimmermann H,Droby A,Steinmetz H,Zipp F,Deichmann R,Klein JC

    更新日期:2016-04-01 00:00:00

  • Pharmacological FMRI in the development of new analgesic compounds.

    abstract::Chronic pain is a major problem for the individual and for society. Despite a range of drugs being available to treat chronic pain, only inadequate pain relief can be achieved for many patients. There is therefore a need for the development of new analgesic compounds. The assessment of pain depends to date entirely on...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1076

    authors: Schweinhardt P,Bountra C,Tracey I

    更新日期:2006-10-01 00:00:00

  • Hemispheric asymmetry in cerebrovascular reactivity of the human primary motor cortex: an in vivo study at 7 T.

    abstract::Current functional MRI (fMRI) approaches assess underlying neuronal activity through monitoring the related local variations in cerebral blood oxygenation, blood volume and blood flow. This vascular response is likely to vary across brain regions and across individuals, depending on the composition of the local vascul...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.3282

    authors: Driver ID,Andoh J,Blockley NP,Francis ST,Gowland PA,Paus T

    更新日期:2015-05-01 00:00:00

  • 1H NMR spin-echo spectroscopy of human erythrocytes. Transformation of exogenous compounds.

    abstract::1H NMR spin-echo spectroscopy has been used to study the metabolism of exogenous compounds in human erythrocytes. The non-invasive nature of the technique and the continuous monitoring makes it ideal to investigate both the conversion of substrates and the occurrence and the nature of the products. Hydrolysis rates ma...

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.1940030603

    authors: Skibsted U,Hansen PE

    更新日期:1990-12-01 00:00:00

  • Noninvasive in situ proton MRS in muscle tissue and bone marrow as a novel approach to identify previous freezing in a completely thawed cadaver.

    abstract::The temporary or permanent storage of human bodies in freezers following a homicide is a documented method for criminal disposal of human corpses. In these cases, the detection of characteristics which indicate that a thawed cadaver or body part was previously frozen provides crucial information for forensic casework....

    journal_title:NMR in biomedicine

    pub_type: 杂志文章

    doi:10.1002/nbm.4220

    authors: Gascho D,Richter H,Karampinos DC,Heimer J,Schaerli S,Thali MJ,Zoelch N

    更新日期:2020-02-01 00:00:00