Impact analysis of autoantibody level and NR2 antibody level in neuropsychiatric SLE treated by methylprednisolone combined with MTX and DXM intrathecal injection.

abstract：:Anions enter from the cytoplasm into the channel pore of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel not via a central pathway but via a single lateral portal or fenestration. High Cl- conductance is dependent on electrostatic attraction of cytoplasmic Cl- ions by four positively charged...

journal_title：Cell biochemistry and biophysics

authors： Linsdell P,Negoda A,Cowley EA,El Hiani Y

更新日期：2020-03-01 00:00:00

abstract：:Previous studies have shown that A. lumbricoides extracts capture sialic acid (SA) from human red blood cells (RBC). The aim of this work was to study hemorheological alterations in vitro caused by parasite larvae. The biorheological action of three larva concentrates of first and second larval stage on group O erythr...

journal_title：Cell biochemistry and biophysics

authors： de León PP,Del Balzo G,Riquelme B

更新日期：2013-03-01 00:00:00

abstract：:Recent advances in the use of the atomic force microscope (AFM) for manipulating cell membranes and membrane proteins are reviewed. Early pioneering work on measurements of the magnitude of the force required to create indentations with defined depth on their surfaces and to separate interacting pairs of avidin-biotin...

journal_title：Cell biochemistry and biophysics

authors： Ikai A,Afrin R

更新日期：2003-01-01 00:00:00

abstract：:The state of crosslinking of microfilaments and the state of myosin-driven contraction are the main determinants of the mechanical properties of the cell cortex underneath the membrane, which is significant for the mechanism of shaping cells. Therefore, any change in the contractile state of the actomyosin network wou...

journal_title：Cell biochemistry and biophysics

authors： Karl I,Bereiter-Hahn J

更新日期：1998-01-01 00:00:00

abstract：:Ezrin is overexpressed in a variety of neoplastic cells and is involved in the later stages of tumor progression and metastasis. The present study investigated the expression and functional significance of ezrin in human brain astrocytoma. Ezrin expression was examined in specimens from healthy human brains (10 autops...

journal_title：Cell biochemistry and biophysics

authors： Mao J,Yuan XR,Xu SS,Jiang XC,Zhao XT

更新日期：2013-01-01 00:00:00

abstract：:Synaptic glutamate receptors play a prominent role in the excitatory neurotransmission in the vertebrate central nervous system. Although elucidation of the functional properties of glutamate receptors using electrophysiologic analyses has yielded important information, methodological and technological limitations hav...

journal_title：Cell biochemistry and biophysics

authors： Vaithianathan T,Manivannan K,Kleene R,Bahr BA,Dey MP,Dityatev A,Suppiramaniam V

更新日期：2005-01-01 00:00:00

abstract：:Dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN) is a cellular receptor for hepatitis C virus for the binding of viral envelope glycoprotein E2. Interaction of DC-SIGN with the E2 may evoke cellular signal transduction implicated in viral pathogenesis. We developed a cell model ...

journal_title：Cell biochemistry and biophysics

authors： Chen QL,Zhu SY,Bian ZQ,Zhao LJ,Cao J,Pan W,Qi ZT

更新日期：2010-01-01 00:00:00

abstract：:The objective of this study is to observe the adult growth hormone level in postoperative pituitary tumor patients of multi-centers, and explore the change of hypophyseal hormones in postoperative pituitary tumor patients. Sixty patients with pituitary tumor admitted during March, 2011-March, 2012 were selected. Posto...

journal_title：Cell biochemistry and biophysics

authors： Cheng JM,Gu JW,Kuang YQ,Ma Y,Xia X,Yang T,Lu M,He WQ,Sun ZY,Zhang YC

更新日期：2015-03-01 00:00:00

abstract：:The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we ...

journal_title：Cell biochemistry and biophysics

authors： Gopalakrishnan C,Kamaraj B,Purohit R

更新日期：2014-12-01 00:00:00

abstract：:Although As2O3 (ATO) has been recommended as the front-line agent for treatment of acute promyelocytic leukemia (APL), particularly for relapsed or refractory APL, it has been associated with profound toxicity. Icariin is a natural compound with activity against a variety of cancers. This study was designed to investi...

journal_title：Cell biochemistry and biophysics

authors： Wang Z,Zhang H,Dai L,Song T,Li P,Liu Y,Wang L

更新日期：2015-09-01 00:00:00

abstract：:Calmodulin (CaM) binds to the FERM domain of 80 kDa erythrocyte protein 4.1R (R30) independently of Ca(2+) but, paradoxically, regulates R30 binding to transmembrane proteins in a Ca(2+)-dependent manner. We have previously mapped a Ca(2+)-independent CaM-binding site, pep11 (A(264)KKLWKVCVEHHTFFR), in 4.1R FERM domai...

journal_title：Cell biochemistry and biophysics

authors： Nunomura W,Isozumi N,Nakamura S,Jinbo Y,Ohki S,Kidokoro S,Wakui H,Takakuwa Y

更新日期：2014-05-01 00:00:00

abstract：:Chloride intracellular channel 1 (CLIC1) is a sensor of oxidative stress in endothelial cells (EC). However, the mechanism by which CLIC1 mediate the regulation of endothelial dysfunction has not been established. In this study, overexpressed CLIC1 impaired the ability of the vascular cells to resist oxidative damage ...

journal_title：Cell biochemistry and biophysics

authors： Lu D,Le Y,Ding J,Dou X,Mao W,Zhu J

更新日期：2021-01-11 00:00:00

abstract：:The simultaneous determination of adhesion and deformability parameters of erythrocytes was carried out through a microfluidic device, which uses an inverted optical microscope with new image acquisition and analysis technologies. Also, an update of the models describing erythrocyte adhesion and deformation was propos...

journal_title：Cell biochemistry and biophysics

authors： Londero CM,Riquelme BD

更新日期：2020-11-07 00:00:00

abstract：:Pro-domain of a cysteine cathepsin contains a highly conserved Ex2Rx2Fx2Nx3Ix3N (ERFNIN) motif. The zymogen structure of cathepsins revealed that the Arg(R) residue of the motif is a central residue of a salt-bridge/H-bond network, stabilizing the scaffold of the pro-domain. Importance of the arginine is also demonstr...

journal_title：Cell biochemistry and biophysics

authors： Aich P,Biswas S

更新日期：2018-06-01 00:00:00

abstract：:A rapid and sensitive liquid chromatography-tandem mass spectrometry assay (LC-MS/MS) with electrospray ionization was developed and validated for the quantitative determination of the concentration of methotrexate (MTX) enantiomers in intracellular and extracellular fluids of HepG2 cells. The analytes were extracted ...

journal_title：Cell biochemistry and biophysics

authors： Wang R,Guo L,Xie H,Zhang J,Li X,Li W,Wang J,Wu X,Jia Z

更新日期：2013-01-01 00:00:00

abstract：:It has been long known that the oncogenic extracellular environment plays an indispensable role in developing and nurturing cancer cell progression and in resistance to standard treatments. However, by how much the biophysical components of tumour extracellular environment contribute to these processes is uncertain. I...

journal_title：Cell biochemistry and biophysics

authors： Sarwar M,Sykes PH,Chitcholtan K,Evans JJ

更新日期：2021-01-12 00:00:00

abstract：:Skin fibrosis is one of the major features of scleroderma. WNT/β-catenin signaling is associated with the progression of skin fibrosis. In this study, we aimed to determine the effect of icaritin (IT), a natural compound, on scleroderma-related skin fibrosis and its mechanisms. We found that IT could reduce the expres...

journal_title：Cell biochemistry and biophysics

authors： Li M,Liu Q,He S,Kong X,Lin J,Huang Y,Wu W,Wu J

更新日期：2020-10-30 00:00:00

abstract：:Structural organization of the cytoplasm by compartmentation is a well established fact for the eukaryotic cell. In prokaryotes, compartmentation is less obvious. Most prokaryotes do not need intracytoplasmic membranes to maintain their vital functions. This review, especially dealing with prokaryotes, will point out ...

journal_title：Cell biochemistry and biophysics

authors： Hoppert M,Mayer F

更新日期：1999-01-01 00:00:00

abstract：:Cellular responses to external signals often reflect alterations in gene expression. The activation of cell surface hormone or growth factor receptors upon the binding of appropriate ligands mobilizes signal transduction cascades that can ultimately impact the activity of defined sets of transcription factors. The int...

journal_title：Cell biochemistry and biophysics

authors： DeFranco DB

更新日期：1999-01-01 00:00:00

abstract：:To investigate the effects of the HDMX polymorphism on sarcoma risk. Relevant studies were identified by searching the PubMed, Embase, and Web of Science databases. Data were extracted by two independent investigators. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated using a fixed-effects model to...

journal_title：Cell biochemistry and biophysics

authors： Xu H,Zhou P,Ti Y,Jia F

更新日期：2014-12-01 00:00:00

abstract：:To assess the image quality of monochromatic imaging from spectral CT in patients with Budd-Chiari syndrome (BCS), fifty patients with BCS underwent spectral CT to generate conventional 140 kVp polychromatic images (group A) and monochromatic images, with energy levels from 40 to 80, 40 + 70, and 50 + 70 keV fusion im...

journal_title：Cell biochemistry and biophysics

authors： Su L,Dong J,Sun Q,Liu J,Lv P,Hu L,Yan L,Gao J

更新日期：2014-11-01 00:00:00

abstract：:Tissue restoration is the process whereby multiple damaged cell types are replaced to restore the histoarchitecture and function to the tissue. Several theories have been proposed to explain the phenomenon of tissue restoration in amphibians and in animals belonging to higher orders. These theories include dedifferent...

journal_title：Cell biochemistry and biophysics

authors： Young HE,Duplaa C,Romero-Ramos M,Chesselet MF,Vourc'h P,Yost MJ,Ericson K,Terracio L,Asahara T,Masuda H,Tamura-Ninomiya S,Detmer K,Bray RA,Steele TA,Hixson D,el-Kalay M,Tobin BW,Russ RD,Horst MN,Floyd JA,Henson NL

更新日期：2004-01-01 00:00:00

abstract：:A simple analytical approximation to an inhomogeneously-broadened dispersion signal is proposed and tested with resonance lines broadened by unresolved hyperfine structure. Spectral parameters may be rapidly and accurately extracted using a nonlinear least-squares fitting algorithm. Combining the new approximation to ...

journal_title：Cell biochemistry and biophysics

authors： Bales BL

更新日期：2017-06-01 00:00:00

abstract：:Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds. This study was designed to evaluate the cardioprotec...

journal_title：Cell biochemistry and biophysics

authors： Adluri RS,Thirunavukkarasu M,Zhan L,Maulik N,Svennevig K,Bagchi M,Maulik G

更新日期：2013-11-01 00:00:00

abstract：:Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

journal_title：Cell biochemistry and biophysics

authors： Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

更新日期：2014-09-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) has been known to enhance the growth of normal hepatocytes, but also to inhibit the growth of neoplastic cells. This article examines the involvement of HGF in the hepatocarcinogenesis caused by peroxisome proliferators (PPs). Up to 78 wk after male F-344 rats were orally given (4-chloro...

journal_title：Cell biochemistry and biophysics

authors： Suga T,Motoki Y,Tamura H,Watanabe T

更新日期：2000-01-01 00:00:00

abstract：:Molecular dynamics simulations, binding free energy calculations, principle component analysis (PCA), and residue interaction network analysis were employed in order to investigate the molecular mechanism of M184I single mutation which played pivotal role in making the HIV-1 reverse transcriptase (RT) totally resistan...

journal_title：Cell biochemistry and biophysics

authors： Moonsamy S,Bhakat S,Walker RC,Soliman ME

更新日期：2016-03-01 00:00:00

abstract：:Escherichia coli has four hydrogenases (Hyd), three genes of which are encoded by the hya, hyb, and hyc operons. The proton-reducing and hydrogen-oxidizing activities of Hyd-2 (hyb) were analyzed in whole cells grown to stationary phase and cell extracts, respectively, during glycerol fermentation using novel double m...

journal_title：Cell biochemistry and biophysics

authors： Trchounian K,Soboh B,Sawers RG,Trchounian A

更新日期：2013-05-01 00:00:00

abstract：:We have examined the association of insulin receptors (IR) and downstream signaling molecules with membrane microdomains in rat basophilic leukemia (RBL-2H3) cells following treatment with insulin or tris(2-pyridinecarbxylato)chromium(III) (Cr(pic)(3)). Single-particle tracking demonstrated that individual IR on these...

journal_title：Cell biochemistry and biophysics

authors： Al-Qatati A,Winter PW,Wolf-Ringwall AL,Chatterjee PB,Van Orden AK,Crans DC,Roess DA,Barisas BG

更新日期：2012-04-01 00:00:00

abstract：:To explore therapeutic effects and underlying mechanism of Salubrinal combined with Ulinastatin (UTI) on acute Paraquat (PQ) poisoning. Four hundred rats were randomly allocated into UTI group, SAL group, SAL + UTI and control group according to random number table with 100 rats in each group. Acute PQ poisoning model...

journal_title：Cell biochemistry and biophysics

authors： Guo H,Jiang C,Sun X

更新日期：2014-12-01 00:00:00