Toward mechanical manipulations of cell membranes and membrane proteins using an atomic force microscope: an invited review.

abstract：:Neural stem cells (NSCs) have widely been used in the treatment of human neurological disorders as cell therapy via intracerebral or intraventricular infusion. However, the migration mechanism required for NSCs homing and recruitment remains to be elucidated. Recently, SDF-1/CXCR4 axis was shown to be responsible for ...

journal_title：Cell biochemistry and biophysics

authors： Xue L,Wang J,Wang W,Yang Z,Hu Z,Hu M,Ding P

更新日期：2014-12-01 00:00:00

abstract：:Mechanical loading is known to promote osteocyte survival, whereas glucocorticoid treatment results in osteocyte apoptosis. Here, we report that BMP-7, which was secreted by osteocyte in response to mechanical loading, exerts anti-apoptotic effect against dexamethasone-induced apoptosis of osteocytes. We further show ...

journal_title：Cell biochemistry and biophysics

authors： Wang Z,Guo J

更新日期：2013-11-01 00:00:00

abstract：:Slow inactivation in voltage-gated sodium channels is a biophysical process that governs the availability of sodium channels over extended periods of time. Slow inactivation, therefore, plays an important role in controlling membrane excitability, firing properties, and spike frequency adaptation. Defective slow inact...

journal_title：Cell biochemistry and biophysics

authors： Vilin YY,Ruben PC

更新日期：2001-01-01 00:00:00

abstract：:Human copper transporter 1 (hCTR1) is the major high affinity copper influx transporter in mammalian cells that also mediates uptake of the cancer chemotherapeutic agent cisplatin. A low resolution structure of hCTR1 determined by cryoelectron microscopy was recently published. Several protein structure simulation tec...

journal_title：Cell biochemistry and biophysics

authors： Tsigelny IF,Sharikov Y,Greenberg JP,Miller MA,Kouznetsova VL,Larson CA,Howell SB

更新日期：2012-07-01 00:00:00

abstract：:The aim of this study is to examine the efficacy of alprostadil liposomal preparation in the treatment of blue toe syndrome. As many as 32 patients with blue toe syndrome were randomized into the test group and a control group. Patients out of the test group were treated with alprostadil liposomal preparation, while t...

journal_title：Cell biochemistry and biophysics

authors： Xi HL,Li R,Tian ZL,Feng S,Jia GL

更新日期：2015-05-01 00:00:00

abstract：:Rotaviruses are one of the worldwide leading causes of gastroenteritis in children under 5 yr old. The rotavirus nonstructural NSP5 is a phosphoprotein implicated in viroplasms formation, whereas NSP6 could have a possible regulatory role of NSP5. It has been reported that N- and C-termini of NSP5 are important for th...

journal_title：Cell biochemistry and biophysics

authors： Samaniego-Hernández M,De León-Rodriguez A,Aparicio-Fabre R,Arias-Ortiz C,Barba de la Rosa AP

更新日期：2006-01-01 00:00:00

abstract：:The airways in asthma and COPD are characterized by an increase in airway smooth muscle (ASM) mass and bronchial vascular changes associated with increased expression of pro-angiogenic growth factors, such as fibroblast growth factors (FGF-1 and FGF-2) and vascular endothelial growth factor (VEGF). We investigated the...

journal_title：Cell biochemistry and biophysics

authors： Willems-Widyastuti A,Vanaudenaerde BM,Vos R,Dilisen E,Verleden SE,De Vleeschauwer SI,Vaneylen A,Mooi WJ,de Boer WI,Sharma HS,Verleden GM

更新日期：2013-11-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8, has been associated with the development of Kaposi's sarcoma, pleural effusion lymphoma, and multicentric Castleman's disease. KSHV is a double-stranded DNA virus that has been classified as a gammaherpesvirus. The viral genome is appro...

journal_title：Cell biochemistry and biophysics

authors： Damania B

更新日期：2004-01-01 00:00:00

abstract：:Spectral karyotyping is a novel technique for chromosome analysis that has been developed based on the approach of the fluorescence in situ hybridization technique. Spectral karyotyping makes it feasible to diagnose a variety of diseases, because of its technology in painting each of the 24 human chromosomes with diff...

journal_title：Cell biochemistry and biophysics

authors： Imataka G,Arisaka O

更新日期：2012-01-01 00:00:00

abstract：:Hip fracture is a kind of osteoporotic fractures in elderly patients. Its important monitoring indicator is to measure bone mineral density (BMD) using DXA. The stress characteristics and material distribution in different parts of the bones can be well simulated by three-dimensional finite element analysis. Our previ...

journal_title：Cell biochemistry and biophysics

authors： Lin ZL,Li PF,Pang ZH,Zheng XH,Huang F,Xu HH,Li QL

更新日期：2015-11-01 00:00:00

abstract：:Osteosarcoma (OS) is the leading primary malignant bone tumor in children and young adults. It is response for a high mortality rate. Nowadays, few researches have been performed on sorafenib against OS and no tools are available to guide the use of sorafenib in the OS treatment. In this study, we aim to investigate t...

journal_title：Cell biochemistry and biophysics

authors： Mei J,Zhu X,Wang Z,Wang Z

更新日期：2014-05-01 00:00:00

abstract：:It has been long known that the oncogenic extracellular environment plays an indispensable role in developing and nurturing cancer cell progression and in resistance to standard treatments. However, by how much the biophysical components of tumour extracellular environment contribute to these processes is uncertain. I...

journal_title：Cell biochemistry and biophysics

authors： Sarwar M,Sykes PH,Chitcholtan K,Evans JJ

更新日期：2021-01-12 00:00:00

abstract：:The study analyzed how enteral ecoimmunonutrition, which comprises probiotics, glutamine, fish oil, and Enteral Nutritional Suspension (TPF), can impact on the enteral permeability and serum Ghrelin activity in severe cerebral stroke patients with lung infection. Among 190 severe cerebral stroke patients with toleranc...

journal_title：Cell biochemistry and biophysics

authors： Xu XD,Shao F

更新日期：2015-01-01 00:00:00

abstract：:Tissue restoration is the process whereby multiple damaged cell types are replaced to restore the histoarchitecture and function to the tissue. Several theories have been proposed to explain the phenomenon of tissue restoration in amphibians and in animals belonging to higher orders. These theories include dedifferent...

journal_title：Cell biochemistry and biophysics

authors： Young HE,Duplaa C,Romero-Ramos M,Chesselet MF,Vourc'h P,Yost MJ,Ericson K,Terracio L,Asahara T,Masuda H,Tamura-Ninomiya S,Detmer K,Bray RA,Steele TA,Hixson D,el-Kalay M,Tobin BW,Russ RD,Horst MN,Floyd JA,Henson NL

更新日期：2004-01-01 00:00:00

abstract：:There are over 10,000 C2H2-type zinc finger (ZF) domains distributed among more than 1,000 ZF proteins in the human genome. These domains are frequently observed to be involved in sequence-specific DNA binding, and uncharacterized domains are typically assumed to facilitate DNA interactions. However, some ZFs also fac...

journal_title：Cell biochemistry and biophysics

authors： Brayer KJ,Kulshreshtha S,Segal DJ

更新日期：2008-01-01 00:00:00

abstract：:The objective of this study is to observe the adult growth hormone level in postoperative pituitary tumor patients of multi-centers, and explore the change of hypophyseal hormones in postoperative pituitary tumor patients. Sixty patients with pituitary tumor admitted during March, 2011-March, 2012 were selected. Posto...

journal_title：Cell biochemistry and biophysics

authors： Cheng JM,Gu JW,Kuang YQ,Ma Y,Xia X,Yang T,Lu M,He WQ,Sun ZY,Zhang YC

更新日期：2015-03-01 00:00:00

abstract：:Despite the improvements in chemotherapy, about 60 % of acute myeloid leukemia (AML) remission patients still relapse. Leukemic stem cells (LSCs) are the main causes for the relapse and refractory. T cell immunoglobulin mucin-3 (TIM-3), a specific surface molecule expressed on LSCs in most types of AML, is a candidate...

journal_title：Cell biochemistry and biophysics

authors： Gao L,Yu S,Zhang X

更新日期：2014-09-01 00:00:00

abstract：:We have studied the mechanisms of NaCl transport in the mammalian proximal tubule. Studies of isolated brush-border membrane vesicles confirmed the presence of Na+-H+ exchange and identified Cl(-)-formate and Cl(-)-oxalate exchangers as possible mechanisms of uphill Cl- entry. We found that formate and oxalate each st...

journal_title：Cell biochemistry and biophysics

authors： Aronson PS

更新日期：2002-01-01 00:00:00

abstract：:We have previously shown that plasma membrane calcium ATPase (PMCA) pump activity is affected by the membrane protein concentration (Vanagas et al., Biochim Biophys Acta 1768:1641-1644, 2007). The results of this study provided evidence for the involvement of the actin cytoskeleton. In this study, we explored the rela...

journal_title：Cell biochemistry and biophysics

authors： Vanagas L,de La Fuente MC,Dalghi M,Ferreira-Gomes M,Rossi RC,Strehler EE,Mangialavori IC,Rossi JP

更新日期：2013-05-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is the primary pathway responsible for the recognition and degradation of misfolded, damaged, or tightly regulated proteins in addition to performing essential roles in DNA repair, cell cycle regulation, cell migration, and the immune response. While traditional biochemical techni...

journal_title：Cell biochemistry and biophysics

authors： Melvin AT,Woss GS,Park JH,Waters ML,Allbritton NL

更新日期：2013-09-01 00:00:00

abstract：:Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare form of primary liver cancer (PLC). It is difficult to make a correct preoperative diagnosis of cHCC-CC because of the lack of special features of the disease. We here present a case of a 68-year-old man who presented with fluctuant fever, ch...

journal_title：Cell biochemistry and biophysics

authors： E C,Xie Y,Yang Y,Ji D,Li W,Zhang X

更新日期：2014-05-01 00:00:00

abstract：:Patients with myocardial ischemic diseases or who are undergoing one of various heart treatments, such as open heart surgery, coronary artery bypass grafting, percutaneous coronary artery intervention or drug thrombolysis, face myocardial ischemia-reperfusion injury (MIRI). However, no effective treatment is currently...

journal_title：Cell biochemistry and biophysics

authors： Zhang C,He M,Ni L,He K,Su K,Deng Y,Li Y,Xia H

更新日期：2020-09-01 00:00:00

abstract：:We investigated theoretically and experimentally the Ca2+-contraction coupling in rat tracheal smooth muscle. [Ca2+]i, isometric contraction and myosin light chain (MLC) phosphorylation were measured in response to 1 mM carbachol. Theoretical modeling consisted in coupling a model of Ca2+-dependent MLC kinase (MLCK) a...

journal_title：Cell biochemistry and biophysics

authors： Mbikou P,Fajmut A,Brumen M,Roux E

更新日期：2006-01-01 00:00:00

abstract：:Nutritional changes can affect either the assembly or disassembly of yeast peroxisomes. In the past decade, insights regarding the molecular mechanisms of peroxisome assembly have been gained chiefly through the cloning of the PEX genes obtained by complementation of corresponding pex mutants in several yeast strains ...

journal_title：Cell biochemistry and biophysics

authors： Sakai Y,Subramani S

更新日期：2000-01-01 00:00:00

abstract：:To reveal protective role of the new Mn(II) complexes with Nicotinyl-L-Tyrosinate and Nicotinyl-L-Tryptophanate Schiff Bases against ionizing radiation. The DNA of the rats liver was isolated on 7, 14, and 30 days after X-ray irradiation. The differences between the DNA of irradiated rats and rats pre-treated with Mn(...

journal_title：Cell biochemistry and biophysics

authors： Karapetyan NH,Malakyan MH,Bajinyan SA,Torosyan AL,Grigoryan IE,Haroutiunian SG

更新日期：2013-01-01 00:00:00

abstract：:Non-esterified fatty acids (NEFAs) act as signaling molecules involved in regulating genes expression to modulate lipid metabolism. However, the regulation mechanism of NEFAs on lipid metabolism in dairy cows is unclear. The AMP-activated protein kinase (AMPK) signaling pathway plays a key role in regulating hepatic l...

journal_title：Cell biochemistry and biophysics

authors： Li X,Li X,Chen H,Lei L,Liu J,Guan Y,Liu Z,Zhang L,Yang W,Zhao C,Fu S,Li P,Liu G,Wang Z

更新日期：2013-01-01 00:00:00

abstract：:A rapid and sensitive liquid chromatography-tandem mass spectrometry assay (LC-MS/MS) with electrospray ionization was developed and validated for the quantitative determination of the concentration of methotrexate (MTX) enantiomers in intracellular and extracellular fluids of HepG2 cells. The analytes were extracted ...

journal_title：Cell biochemistry and biophysics

authors： Wang R,Guo L,Xie H,Zhang J,Li X,Li W,Wang J,Wu X,Jia Z

更新日期：2013-01-01 00:00:00

abstract：:To investigate the protective effect of secretory receptor for advanced glycation endproducts (sRAGE) on the fetal development using rat model of gestational diabetes mellitus (GDM). The model of pregnant rats with intrauterine hyperglycemia was established by intraperitoneal injection of 25 mg/kg streptozotocin (STZ)...

journal_title：Cell biochemistry and biophysics

authors： Tang X,Qin Q,Xie X,He P

更新日期：2015-03-01 00:00:00

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:Depression is a common emotional disorder associated with increased risk of suicide and rate of disability. In this double-blinded control study, we tested the efficacy of modified electroconvulsive therapy (MECT) in patients with treatment resistant depression (TRD) using the Hamilton Depression Rating Scale for Depr...

journal_title：Cell biochemistry and biophysics

authors： Lin Z,He H,Zhang C,Wang Z,Jiang M,Li Q,Lan X,Zhang M,Huang X

更新日期：2015-04-01 00:00:00