Simultaneous Determination of Human Erythrocyte Deformability and Adhesion Energy: A Novel Approach Using a Microfluidic Chamber and the "Glass Effect".

abstract：:Although aggressive therapeutic regimen has been applied in the treatment of Glioblastoma (GBM), the prognosis of patients with GBM remains poor. Preclinical studies have demonstrated the efficacy of Suntinib in GBM both in vitro and in vivo. In this study, we showed that the cytotoxicity was enhanced by transfection ...

journal_title：Cell biochemistry and biophysics

authors： Liu H,Liu Z,Jiang B,Huo L,Liu J,Lu J

更新日期：2015-06-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of tumor necrosis factor-alpha (TNF-α) inhibitor-infliximab on ankylosing spondylitis (AS) patients and detect the serum level of HLA-B27 and PDCD-1 before and after TNF inhibitor treatment. 138 patients at active stage of AS were treated with infliximab; serum was coll...

journal_title：Cell biochemistry and biophysics

authors： Chen X,Zhou X,Li X,Tang J,Hu X,Wang J,Xu C

更新日期：2014-11-01 00:00:00

abstract：:Resveratrol (RSV) is known for its antioxidant properties; however, this compound has been proposed to have cytotoxic and pro-oxidant effects depending on its concentration and time of exposure. We previously reported the cell cycle arrest effect of low doses of RSV in GRX cells, an activated hepatic stellate cell mod...

journal_title：Cell biochemistry and biophysics

authors： Martins LA,Coelho BP,Behr G,Pettenuzzo LF,Souza IC,Moreira JC,Borojevic R,Gottfried C,Guma FC

更新日期：2014-03-01 00:00:00

abstract：:To assess the image quality of monochromatic imaging from spectral CT in patients with Budd-Chiari syndrome (BCS), fifty patients with BCS underwent spectral CT to generate conventional 140 kVp polychromatic images (group A) and monochromatic images, with energy levels from 40 to 80, 40 + 70, and 50 + 70 keV fusion im...

journal_title：Cell biochemistry and biophysics

authors： Su L,Dong J,Sun Q,Liu J,Lv P,Hu L,Yan L,Gao J

更新日期：2014-11-01 00:00:00

abstract：:Elevated blood pressure is regarded as an independent risk factor for cardiovascular diseases and diabetes. We examined the relation between hematocrit and pre-hypertension as well as the effect of sex, obesity, fasting glucose, and lipids in Chinese adults. The study samples were from a community-based health examina...

journal_title：Cell biochemistry and biophysics

authors： Liu X,Liang J,Qiu Q,Zhu Y,Sun Y,Ying P,Teng F,Wang Y,Qi L

更新日期：2015-03-01 00:00:00

abstract：:Endothelin-1 (ET-1) is a potent endogenously derived vasoconstrictor, which increases pulmonary hypertension via stimulation of [Ca2+]i level in pulmonary artery smooth muscle cells (PASMCs). In this communication, we sought to investigate the mechanism by which ET-1 causes stimulation of Ca2+ concentration in caveola...

journal_title：Cell biochemistry and biophysics

authors： Sarkar J,Chakraborti T,Pramanik PK,Ghosh P,Mandal A,Chakraborti S

更新日期：2020-10-23 00:00:00

abstract：:Mechanics of cancer cells are directly linked to their metastatic potential, or ability to produce a secondary tumor at a distant site. Metastatic cells survive in the circulatory system in a non-adherent state, and can squeeze through barriers in the body. Such considerable structural changes in cells rely on rapid r...

journal_title：Cell biochemistry and biophysics

authors： Gal N,Weihs D

更新日期：2012-07-01 00:00:00

abstract：:Red blood cell (RBC) adhesion to vessel wall endothelium is a potent catalyst of vascular occlusion and occurs in oxidative stress states such as hemoglobinopathies and cardiovascular conditions. These are often treated with vitamin E (VitE), a "classic" antioxidant. In this study, we examined the effects of VitE on R...

journal_title：Cell biochemistry and biophysics

authors： Koshkaryev A,Barshtein G,Yedgar S

更新日期：2010-04-01 00:00:00

abstract：:A number of case-control studies have been conducted to investigate the relationship between the ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms and risk of coronary heart disease (CHD). However, the results have been inconclusive. The purpose of the present study is to investigate whether this polymorp...

journal_title：Cell biochemistry and biophysics

authors： Liu N,Hou M,Ren W,Cao J,Wu H,Zhou W

更新日期：2015-01-01 00:00:00

abstract：:Curcumin possesses anti-cancer effects. In the current study, we tested the effect of curcumin on cell proliferation, viability, apoptosis, cell cycle phases, and activation of the PI3K/Akt pathway in the renal cell carcinoma (RCC) cell line RCC-949. We observed that cell proliferation and viability were markedly inhi...

journal_title：Cell biochemistry and biophysics

authors： Zhang H,Xu W,Li B,Zhang K,Wu Y,Xu H,Wang J,Zhang J,Fan R,Wei J

更新日期：2015-12-01 00:00:00

abstract：:Rotaviruses are one of the worldwide leading causes of gastroenteritis in children under 5 yr old. The rotavirus nonstructural NSP5 is a phosphoprotein implicated in viroplasms formation, whereas NSP6 could have a possible regulatory role of NSP5. It has been reported that N- and C-termini of NSP5 are important for th...

journal_title：Cell biochemistry and biophysics

authors： Samaniego-Hernández M,De León-Rodriguez A,Aparicio-Fabre R,Arias-Ortiz C,Barba de la Rosa AP

更新日期：2006-01-01 00:00:00

abstract：:The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. To clarify the function of peroxisomal and cytosolic Thiolase Is, the site-directed mutation leading ...

journal_title：Cell biochemistry and biophysics

authors： Ueda M,Kanayama N,Tanaka A

更新日期：2000-01-01 00:00:00

abstract：:STAT3 pathway plays an important role in the growth of diffuse large B-cell lymphoma (DLBCL) cells. Here we investigated the antitumor activity of Quercetin, a flavonoid compound, in combination with rituximab in DLBCL cell lines in vitro. We found that Quercetin synergistically enhanced rituximab-induced growth inhib...

journal_title：Cell biochemistry and biophysics

authors： Li X,Wang X,Zhang M,Li A,Sun Z,Yu Q

更新日期：2014-11-01 00:00:00

abstract：:The aim of the study was to investigate changes in the plasma antioxidative activity and in lipid peroxidation after administration of endothelin-1 (ET-1) and endothelin receptor blockers and additionally, to estimate blood pressure. The study was performed on male Wistar rats (n = 6 per group) divided into 4 groups w...

journal_title：Cell biochemistry and biophysics

authors： Kleniewska P,Kowalczyk A,Ciesla W,Goraca A

更新日期：2015-04-01 00:00:00

abstract：:To investigate if the 12-lead resting electrocardiogram (ECG) is a predictor of left ventricular (LV) functional recovery after revascularization of chronic total coronary artery occlusions (CTO). Revascularization was performed in 58 CTO patients who had impaired regional wall motion. The 12-lead resting ECG was used...

journal_title：Cell biochemistry and biophysics

authors： Yue W,Wang G,Zhang X,Chen B,Wang X,Huangfu F,Jia R

更新日期：2014-09-01 00:00:00

abstract：:To investigate the protective effect of secretory receptor for advanced glycation endproducts (sRAGE) on the fetal development using rat model of gestational diabetes mellitus (GDM). The model of pregnant rats with intrauterine hyperglycemia was established by intraperitoneal injection of 25 mg/kg streptozotocin (STZ)...

journal_title：Cell biochemistry and biophysics

authors： Tang X,Qin Q,Xie X,He P

更新日期：2015-03-01 00:00:00

abstract：:Bioactive materials present important micro-environmental cues that induce specific intracellular signaling responses which ultimately determine cell behavior. For example, vascular endothelial cells on a normal vessel wall resist inflammation and thrombosis, but the same cells seeded on an artificial vascular graft o...

journal_title：Cell biochemistry and biophysics

authors： Caplan MR,Shah MM

更新日期：2009-01-01 00:00:00

abstract：:Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

journal_title：Cell biochemistry and biophysics

authors： Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

更新日期：2009-01-01 00:00:00

abstract：:The aim of the present work is to evaluate the effect of caffeine, the world's most popular psychoactive drug, on the electric activity of the rat's brain that exposed to extremely low-frequency magnetic field (ELF-MF), during 15 days. The obtained results showed that administration of caffeine in a group of rats by d...

journal_title：Cell biochemistry and biophysics

authors： El Gohary MI,Salama AA,El Saeid AA,El Sayed TM,Kotb HSh

更新日期：2013-01-01 00:00:00

abstract：:The study's objective was to evaluate the applicability of different endovascular methods for treatment of refractory type of Budd-Chiari syndrome (BCS) under specific scenarios frequently encountered in patients. The treatment methods were evaluated in 197 patients with the following four types of refractory BCS: les...

journal_title：Cell biochemistry and biophysics

authors： Gao Y,Chen S,Yu C

更新日期：2011-11-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) has been known to enhance the growth of normal hepatocytes, but also to inhibit the growth of neoplastic cells. This article examines the involvement of HGF in the hepatocarcinogenesis caused by peroxisome proliferators (PPs). Up to 78 wk after male F-344 rats were orally given (4-chloro...

journal_title：Cell biochemistry and biophysics

authors： Suga T,Motoki Y,Tamura H,Watanabe T

更新日期：2000-01-01 00:00:00

abstract：:A method is presented to separate rabbit cardiac ventricular myosin isoenzymes (V(1), V(2), V(3)), which are large and important contractile proteins. This polyacrylamide gel electrophoresis--using a slab minigel format--does not involve preparation of an acrylamide gradient or denaturing conditions. The isoenzyme mig...

journal_title：Cell biochemistry and biophysics

authors： Garcia Pomblum SC,Pomblum VJ,Gams E,Reiser PJ,Schipke JD

更新日期：2003-01-01 00:00:00

abstract：:To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

journal_title：Cell biochemistry and biophysics

authors： Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

更新日期：2014-06-01 00:00:00

abstract：:In previous work, decolorization of malachite green (MG) was studied in Aspergillus niger in the presence and absence of calcium chloride stress. Decolorization took place within 24 h, and a signal transduction process that initiated MG decolorization was suggested to be involved. In the present study, further investi...

journal_title：Cell biochemistry and biophysics

authors： Gomaa OM,Selim NS,Linz JE

更新日期：2013-01-01 00:00:00

abstract：:Myocardium viability in ischemic heart failure (HF) may affect the effect of cardiac resynchronization therapy (CRT). We hypothesized that longitudinal strain of 2D-STE, which reflects myocardium viability, can predict the response to CRT in patients with ischemic HF. 2D-STE was performed in 42 patients with HF, 1 wee...

journal_title：Cell biochemistry and biophysics

authors： Ma CY,Liu S,Yang J,Tang L,Zhang LM,Li N,Yu B

更新日期：2014-09-01 00:00:00

abstract：:In this study, the anti-proliferative effect of physcion, an anthraquinone derivative isolated and characterized from both terrestrial and marine sources, against human gastric cancer SGC-7901 cells was investigated and the underlying mechanisms were explored. Physcion reduced SGC-7901 cell viability in a dose- and ti...

journal_title：Cell biochemistry and biophysics

authors： Xiong Y,Ren L,Wang Z,Hu Z,Zhou Y

更新日期：2015-11-01 00:00:00

abstract：:The authors studied the nuclear magnetic resonance films and the expression of MMP-1 and TIMP-1 in disk specimens' of patients who had undergone operations for lumbar disk herniation. Forty-one lumbar disk patients were evaluated imaging for degenerative changes and their disk specimens immunohistochemical expression ...

journal_title：Cell biochemistry and biophysics

authors： Xu H,Mei Q,He J,Liu G,Zhao J,Xu B

更新日期：2014-07-01 00:00:00

abstract：:There are over 10,000 C2H2-type zinc finger (ZF) domains distributed among more than 1,000 ZF proteins in the human genome. These domains are frequently observed to be involved in sequence-specific DNA binding, and uncharacterized domains are typically assumed to facilitate DNA interactions. However, some ZFs also fac...

journal_title：Cell biochemistry and biophysics

authors： Brayer KJ,Kulshreshtha S,Segal DJ

更新日期：2008-01-01 00:00:00

abstract：:The airways in asthma and COPD are characterized by an increase in airway smooth muscle (ASM) mass and bronchial vascular changes associated with increased expression of pro-angiogenic growth factors, such as fibroblast growth factors (FGF-1 and FGF-2) and vascular endothelial growth factor (VEGF). We investigated the...

journal_title：Cell biochemistry and biophysics

authors： Willems-Widyastuti A,Vanaudenaerde BM,Vos R,Dilisen E,Verleden SE,De Vleeschauwer SI,Vaneylen A,Mooi WJ,de Boer WI,Sharma HS,Verleden GM

更新日期：2013-11-01 00:00:00

abstract：:The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy. Sixty-four adult male rats, weighing from 180 to 200 g, were randomly divided into four groups: ten in normal group, ten in sham group, 44 in model group established by inducing...

journal_title：Cell biochemistry and biophysics

authors： Yang F,Liu Z,Wang Y,Li Z,Yu H,Wang Q

更新日期：2014-12-01 00:00:00