Curcumin Promotes Cell Cycle Arrest and Inhibits Survival of Human Renal Cancer Cells by Negative Modulation of the PI3K/AKT Signaling Pathway.

abstract：:Epithelial ovarian cancer (EOC) is the second leading cause of death from gynecological malignancies worldwide. Enhancer of zeste homology 2 (EZH2), participating in gene expression silencing by trimethylating histone 3 lysine 27 (H3K27me3), is often up-regulated in EOC. ARHI, an imprinted tumor-suppressor gene, is ma...

journal_title：Cell biochemistry and biophysics

authors： Fu Y,Chen J,Pang B,Li C,Zhao J,Shen K

更新日期：2015-01-01 00:00:00

abstract：:Structural organization of the cytoplasm by compartmentation is a well established fact for the eukaryotic cell. In prokaryotes, compartmentation is less obvious. Most prokaryotes do not need intracytoplasmic membranes to maintain their vital functions. This review, especially dealing with prokaryotes, will point out ...

journal_title：Cell biochemistry and biophysics

authors： Hoppert M,Mayer F

更新日期：1999-01-01 00:00:00

abstract：:Human copper transporter 1 (hCTR1) is the major high affinity copper influx transporter in mammalian cells that also mediates uptake of the cancer chemotherapeutic agent cisplatin. A low resolution structure of hCTR1 determined by cryoelectron microscopy was recently published. Several protein structure simulation tec...

journal_title：Cell biochemistry and biophysics

authors： Tsigelny IF,Sharikov Y,Greenberg JP,Miller MA,Kouznetsova VL,Larson CA,Howell SB

更新日期：2012-07-01 00:00:00

abstract：:A simple analytical approximation to an inhomogeneously-broadened dispersion signal is proposed and tested with resonance lines broadened by unresolved hyperfine structure. Spectral parameters may be rapidly and accurately extracted using a nonlinear least-squares fitting algorithm. Combining the new approximation to ...

journal_title：Cell biochemistry and biophysics

authors： Bales BL

更新日期：2017-06-01 00:00:00

abstract：:Non-esterified fatty acids (NEFAs) act as signaling molecules involved in regulating genes expression to modulate lipid metabolism. However, the regulation mechanism of NEFAs on lipid metabolism in dairy cows is unclear. The AMP-activated protein kinase (AMPK) signaling pathway plays a key role in regulating hepatic l...

journal_title：Cell biochemistry and biophysics

authors： Li X,Li X,Chen H,Lei L,Liu J,Guan Y,Liu Z,Zhang L,Yang W,Zhao C,Fu S,Li P,Liu G,Wang Z

更新日期：2013-01-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is the primary pathway responsible for the recognition and degradation of misfolded, damaged, or tightly regulated proteins in addition to performing essential roles in DNA repair, cell cycle regulation, cell migration, and the immune response. While traditional biochemical techni...

journal_title：Cell biochemistry and biophysics

authors： Melvin AT,Woss GS,Park JH,Waters ML,Allbritton NL

更新日期：2013-09-01 00:00:00

abstract：:We identified significantly higher expression of the genes glycogen debranching enzyme 6 (AGL), enolase 1 (ENOSF1), ectonucleotide pyrophosphatase 2 (ENPP2_1), glutathione S-transferase 3 (GSTM3_3) and mannosidase (MAN2B2) from human left cerebrums versus chimpanzees. Yet the distinct low- and high-expression AGL, ENO...

journal_title：Cell biochemistry and biophysics

authors： Sun L,Wang L,Jiang M,Huang J,Lin H

更新日期：2011-12-01 00:00:00

abstract：:Establishment of a detection platform for glioblastoma-dendritic cell (DC) vaccine preparation and to determine the efficacy of the vaccine in a clinical trial. Autologous glioblastoma-DC vaccine was prepared from a glioblast specimen procured from surgical resection. The specimen was used to enrich the vaccine with p...

journal_title：Cell biochemistry and biophysics

authors： Jie X,Hua L,Jiang W,Feng F,Feng G,Hua Z

更新日期：2012-01-01 00:00:00

abstract：:Several single nucleotide polymorphisms (SNPs) within the CTLA-4 gene and elevated serum levels of soluble CTLA-4 (sCTLA-4) have been associated with autoimmunity including rheumatoid arthritis (RA). In this case-control study, we evaluated the relationship between the -319C/T (rs5742909) and CT60 G/A (rs3087243) SNPs...

journal_title：Cell biochemistry and biophysics

authors： Torres-Carrillo N,Ontiveros-Mercado H,Torres-Carrillo NM,Parra-Rojas I,Rangel-Villalobos H,Ramírez-Dueñas MG,Gutiérrez-Ureña SR,Valle Y,Muñoz-Valle JF

更新日期：2013-01-01 00:00:00

abstract：:A sensitive and reliable ultra-pressure liquid chromatography with tandem mass spectrometry (UPLC-MS) was developed and validated for simultaneous quantification of six main bioactive components, i.e., calycosin-7-O-β-D-glucoside, ononin, calycosin, formononetin, astragaloside IV, and astragaloside II in rat plasma af...

journal_title：Cell biochemistry and biophysics

authors： Liu XH,Zhao JB,Guo L,Yang YL,Hu F,Zhu RJ,Feng SL

更新日期：2014-09-01 00:00:00

abstract：:Severe acute pancreatitis (SAP) is a common acute abdominal disease. This study was designed to investigate the preventive effects of curcumin on SAP and its possible mechanism of action. We observed increased volume of ascites, serum AMY, IL-6, and TNF-α levels, and expression of TLR-4 and NF-κB mRNA and protein in a...

journal_title：Cell biochemistry and biophysics

authors： Zhong K

更新日期：2015-09-01 00:00:00

abstract：:A rapid and sensitive liquid chromatography-tandem mass spectrometry assay (LC-MS/MS) with electrospray ionization was developed and validated for the quantitative determination of the concentration of methotrexate (MTX) enantiomers in intracellular and extracellular fluids of HepG2 cells. The analytes were extracted ...

journal_title：Cell biochemistry and biophysics

authors： Wang R,Guo L,Xie H,Zhang J,Li X,Li W,Wang J,Wu X,Jia Z

更新日期：2013-01-01 00:00:00

abstract：:The purpose of this study was to investigate the incidence and risk factors of infections associated with totally implantable venous-access ports (TIVAPs) in our hospital. From April 2007 through November 2013, a total of 1,026 patients with TIVAP were included in this study. We retrospectively analyzed the incidence ...

journal_title：Cell biochemistry and biophysics

authors： Ji L,Yang J,Miao J,Shao Q,Cao Y,Li H

更新日期：2015-05-01 00:00:00

abstract：:Calcium channel blockers have been used in the treatment of coronary artery spasm for many years. However, there is insufficient knowledge about their application to treat atrioventricular block caused by coronary spasm. Clinical data of five patients who were diagnosed with coronary spasm caused by atrioventricular b...

journal_title：Cell biochemistry and biophysics

authors： Gao B,Zhang Z,Qian J,Cao C,Hua X,Chu M,He X,Zeng H

更新日期：2015-06-01 00:00:00

abstract：:This study is aimed to investigate the efficacy and underlying the mechanism of propofol in treatment of ischemia reperfusion (IR)-induced lung injury in rats, providing a novel insight of therapeutic strategy for IR-induced lung injury. 120 healthy SD rats were selected and randomly divided into sham operation group,...

journal_title：Cell biochemistry and biophysics

authors： Yang P,Yang N,Zhang X,Xu X

更新日期：2014-12-01 00:00:00

abstract：:A number of case-control studies have been conducted to investigate the relationship between the ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms and risk of coronary heart disease (CHD). However, the results have been inconclusive. The purpose of the present study is to investigate whether this polymorp...

journal_title：Cell biochemistry and biophysics

authors： Liu N,Hou M,Ren W,Cao J,Wu H,Zhou W

更新日期：2015-01-01 00:00:00

abstract：:Promotion of apoptosis (which is frequently dependent on functional p53) is thought to be critical for the effectiveness of chemotherapy or radiotherapy. Studies in this as well as other laboratories have demonstrated that breast tumor cells are relatively refractory to apoptosis in response to modalities that induce ...

journal_title：Cell biochemistry and biophysics

authors： Gewirtz DA,Sundaram S,Magnet KJ

更新日期：2000-01-01 00:00:00

abstract：:There is an emergent need for improving the microsurgical technique of variant arterial anastomosis to reduce the often seen surgery-related complications. We describe in this article our experience in improving this technique, in 73 living donor liver grafts (64 right lobes, 9 left lobes) in patients with end-stage l...

journal_title：Cell biochemistry and biophysics

authors： Liang Y,Ye S,Shi X,Ji W,Duan W,Luo Y,Dong J

更新日期：2013-03-01 00:00:00

abstract：:Calmodulin (CaM) binds to the FERM domain of 80 kDa erythrocyte protein 4.1R (R30) independently of Ca(2+) but, paradoxically, regulates R30 binding to transmembrane proteins in a Ca(2+)-dependent manner. We have previously mapped a Ca(2+)-independent CaM-binding site, pep11 (A(264)KKLWKVCVEHHTFFR), in 4.1R FERM domai...

journal_title：Cell biochemistry and biophysics

authors： Nunomura W,Isozumi N,Nakamura S,Jinbo Y,Ohki S,Kidokoro S,Wakui H,Takakuwa Y

更新日期：2014-05-01 00:00:00

abstract：:In previous work, decolorization of malachite green (MG) was studied in Aspergillus niger in the presence and absence of calcium chloride stress. Decolorization took place within 24 h, and a signal transduction process that initiated MG decolorization was suggested to be involved. In the present study, further investi...

journal_title：Cell biochemistry and biophysics

authors： Gomaa OM,Selim NS,Linz JE

更新日期：2013-01-01 00:00:00

abstract：:P2Y receptors are classified as P2 purinergic receptors that belong to the superfamily of G-protein coupled receptors. They are distinguishable from P1 (adenosine) receptors in that they bind adenine and/or uracil nucleotide triphosphates or diphosphates depending on the subtype. Over the past decade, P2Y receptors ha...

journal_title：Cell biochemistry and biophysics

authors： Lee SY,O'Grady SM

更新日期：2003-01-01 00:00:00

abstract：:Right ventricular hypertrophy and failure are prominent features in cyanotic congenital heart disease, tetralogy of Fallot (TF). Patients with TF require primary cardiac surgery at a very young age. To gain insight into the underlying molecular mechanisms of right ventricular hypertrophy and to identify gene(s) involv...

journal_title：Cell biochemistry and biophysics

authors： Sharma HS,Peters TH,Moorhouse MJ,van der Spek PJ,Bogers AJ

更新日期：2006-01-01 00:00:00

abstract：:Curcumin is a yellow-orange dye widely used as a spice, food coloring and food preservative. It also exhibits a broad range of therapeutic effects against different disorders such as cancer, diabetes, or neurodegenerative diseases. As a compound insoluble in water curcumin accumulates in cell membranes and due to this...

journal_title：Cell biochemistry and biophysics

authors： Duda M,Cygan K,Wisniewska-Becker A

更新日期：2020-06-01 00:00:00

abstract：:We performed a meta-analysis to compare therapeutic outcome/safety of drug-eluting stent (DES) and conventional in-stent restenosis (ISR) treatments. We browsed through large volume of clinical data by searching MEDLINE, EMBASE, Cochrane central register of controlled trials, and EBSCO databases. In this study, 11 ran...

journal_title：Cell biochemistry and biophysics

authors： Sun Y,Li L,Su Q,Lu Y

更新日期：2014-01-01 00:00:00

abstract：:Recent studies have shown that endothelial progenitor cells (EPCs) participated in angiogenic effects of nicotine and nicotine dose dependently increased the functional activity of early EPCs. The effects of nicotine on late EPCs remain to be determined. Therefore, we investigated whether nicotine had influences on th...

journal_title：Cell biochemistry and biophysics

authors： Yu M,Li Z,Shu Z,Liu Q,Sun J,Tan X

更新日期：2014-11-01 00:00:00

abstract：:Red blood cell (RBC) adhesion to vessel wall endothelium is a potent catalyst of vascular occlusion and occurs in oxidative stress states such as hemoglobinopathies and cardiovascular conditions. These are often treated with vitamin E (VitE), a "classic" antioxidant. In this study, we examined the effects of VitE on R...

journal_title：Cell biochemistry and biophysics

authors： Koshkaryev A,Barshtein G,Yedgar S

更新日期：2010-04-01 00:00:00

abstract：:A quality control method of highly diluted and potentized homeopathic remedies is important for curing patients applying homeopathic therapy. Lenger detected photons in highly potentized homeopathic remedies by delayed luminescence. The photons of Argentum metallicum 100MK and Cantharis 100MK magnetically bound to the...

journal_title：Cell biochemistry and biophysics

authors： Lenger K,Bajpai RP,Spielmann M

更新日期：2014-03-01 00:00:00

abstract：:Far from now are the days when investigators raced to identify the proteolytic system responsible for the degradation of their favorite protein. Nowadays, it is well accepted that a given protein can be degraded by different systems depending on factors such as cell type, cellular conditions, or functionality of each ...

journal_title：Cell biochemistry and biophysics

authors： Park C,Cuervo AM

更新日期：2013-09-01 00:00:00

abstract：:Many macrophage functions are modulated by fatty acids (FAs), including cytokine release, such as tumor necrosis factor-α (TNF-α). TNF-α is of great interest due to its role in the inflammation process observed in several diseases such as rheumatoid arthritis, atherosclerosis, and obesity. However, the mechanisms by w...

journal_title：Cell biochemistry and biophysics

authors： de Lima-Salgado TM,Alba-Loureiro TC,do Nascimento CS,Nunes MT,Curi R

更新日期：2011-03-01 00:00:00

abstract：:The aim of the study was to evaluate the clinical efficacy of hydrogen sulfide (H2S) treatment on the endothelin-induced cardiac hypertrophy. Sixty-four adult male rats, weighing from 180 to 200 g, were randomly divided into four groups: ten in normal group, ten in sham group, 44 in model group established by inducing...

journal_title：Cell biochemistry and biophysics

authors： Yang F,Liu Z,Wang Y,Li Z,Yu H,Wang Q

更新日期：2014-12-01 00:00:00