Selective autophagy: talking with the UPS.

Abstract:

:Far from now are the days when investigators raced to identify the proteolytic system responsible for the degradation of their favorite protein. Nowadays, it is well accepted that a given protein can be degraded by different systems depending on factors such as cell type, cellular conditions, or functionality of each proteolytic pathway. The realization of this sharing of substrates among pathways has also helped to unveil deeper levels of communication among the different proteolytic systems. Thus, cells often respond to blockage of one degradative mechanism by upregulating any of the other available pathways. In addition, effectors and regulators of one proteolytic system can be degraded by a different proteolytic pathway that exerts, in this way, a regulatory function. In this mini review, we describe the different levels of cross-talk among autophagic pathways and the ubiquitin/proteasome system. We also provide examples of how this proteolytic communication is used for compensatory purposes in different pathological conditions and discuss the possible therapeutic potential of targeting the modulators of the cross-talk among proteolytic pathways.

journal_name

Cell Biochem Biophys

authors

Park C,Cuervo AM

doi

10.1007/s12013-013-9623-7

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

3-13

issue

1

eissn

1085-9195

issn

1559-0283

journal_volume

67

pub_type

杂志文章,评审
  • Single channel recordings from synaptosomal AMPA receptors.

    abstract::Synaptic glutamate receptors play a prominent role in the excitatory neurotransmission in the vertebrate central nervous system. Although elucidation of the functional properties of glutamate receptors using electrophysiologic analyses has yielded important information, methodological and technological limitations hav...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:42:1:075

    authors: Vaithianathan T,Manivannan K,Kleene R,Bahr BA,Dey MP,Dityatev A,Suppiramaniam V

    更新日期:2005-01-01 00:00:00

  • Better prognosis in newborns with trisomy 13 who received intensive treatments: a retrospective study of 16 patients.

    abstract::Intensive treatment for newborns with trisomy 13 is controversial because of their lethal prognosis. We report the better life prognosis of patients with trisomy 13 who received intensive treatment. At our hospital, we provided an intensive management to such patients including resuscitation and surgical procedures as...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9355-0

    authors: Tsukada K,Imataka G,Suzumura H,Arisaka O

    更新日期:2012-07-01 00:00:00

  • Structural adaptation in adult rabbit ventricular myocytes: influence of dynamic physical interaction with fibroblasts.

    abstract::The mechanism of induction of cardiomyocyte (CM) dedifferentiation, as seen in chronic hibernating myocardium, is largely unknown. Recently, a cellular model was proposed consisting of long-term cocultures of adult rabbit CMs and cardiac fibroblasts in which typical structural characteristics of hibernation-like dedif...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:44:1:119

    authors: Driesen RB,Verheyen FK,Dispersyn GD,Thoné F,Lenders MH,Ramaekers FC,Borgers M

    更新日期:2006-01-01 00:00:00

  • Advantages, Disadvantages, and Trend of Integrative Medicine in the Treatment of Heart Failure.

    abstract::Integrative medicine therapy using traditional Chinese medicine (TCM) combined with western medicine has shown some advantages in treating heart failure (HF), such as holistic concept; multi-target treatment; dialectical logic; personalized therapy; formulae compatibility; and reduction of side effects of western medi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s12013-014-0466-7

    authors: Zhang P

    更新日期:2015-06-01 00:00:00

  • Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer.

    abstract::The phosphatidylinositol 3-kinase/AKT (PI3K/AKT) pathway plays a critical role in human cancer. We determined the expression patterns of class I PI3K catalytic subunits and evaluated their importance in the development or progression of colorectal cancer (CRC). For this purpose, expression of class I PI3K isoforms was...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9257-6

    authors: Cui B,Tao J,Yang Y

    更新日期:2012-01-01 00:00:00

  • Ecto-mesenchymal stem cells from facial process: potential for muscle regeneration.

    abstract::Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-9964-x

    authors: Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

    更新日期:2014-09-01 00:00:00

  • Effects of Curcumin on Lipid Membranes: an EPR Spin-label Study.

    abstract::Curcumin is a yellow-orange dye widely used as a spice, food coloring and food preservative. It also exhibits a broad range of therapeutic effects against different disorders such as cancer, diabetes, or neurodegenerative diseases. As a compound insoluble in water curcumin accumulates in cell membranes and due to this...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-020-00906-5

    authors: Duda M,Cygan K,Wisniewska-Becker A

    更新日期:2020-06-01 00:00:00

  • An all-atom model of the structure of human copper transporter 1.

    abstract::Human copper transporter 1 (hCTR1) is the major high affinity copper influx transporter in mammalian cells that also mediates uptake of the cancer chemotherapeutic agent cisplatin. A low resolution structure of hCTR1 determined by cryoelectron microscopy was recently published. Several protein structure simulation tec...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9358-x

    authors: Tsigelny IF,Sharikov Y,Greenberg JP,Miller MA,Kouznetsova VL,Larson CA,Howell SB

    更新日期:2012-07-01 00:00:00

  • Correlation of matrix metalloproteinases-1 and tissue inhibitor of metalloproteinases-1 with patient age and grade of lumbar disk herniation.

    abstract::The authors studied the nuclear magnetic resonance films and the expression of MMP-1 and TIMP-1 in disk specimens' of patients who had undergone operations for lumbar disk herniation. Forty-one lumbar disk patients were evaluated imaging for degenerative changes and their disk specimens immunohistochemical expression ...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-9815-9

    authors: Xu H,Mei Q,He J,Liu G,Zhao J,Xu B

    更新日期:2014-07-01 00:00:00

  • Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells.

    abstract::Tetrahydrobiopterin (BH4) is a member of the pterin family that has a core structure of pyrazino-2,3-d-pyrimidine rings. Because BH4 is an essential cofactor for the biosynthesis of nitric oxide (a major vasodilator), there is growing interest in BH4 biochemistry in endothelial cells (the cells that line blood vessels...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/CBB:41:3:415

    authors: Shi W,Meininger CJ,Haynes TE,Hatakeyama K,Wu G

    更新日期:2004-01-01 00:00:00

  • Experiences of microsurgical reconstruction for variant hepatic artery in living donor liver transplantation.

    abstract::There is an emergent need for improving the microsurgical technique of variant arterial anastomosis to reduce the often seen surgery-related complications. We describe in this article our experience in improving this technique, in 73 living donor liver grafts (64 right lobes, 9 left lobes) in patients with end-stage l...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9421-7

    authors: Liang Y,Ye S,Shi X,Ji W,Duan W,Luo Y,Dong J

    更新日期:2013-03-01 00:00:00

  • Implementation of a fast-track clinical pathway decreases postoperative length of stay and hospital charges for liver resection.

    abstract::A fast-track clinical pathway is designed to streamline patient care delivery and maximize cost effectiveness. It has decreased postoperative length of stay (LOS) and hospital charges for many surgical procedures. However, data on clinical pathways after liver surgery are sparse. This study examined whether use of a f...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-011-9203-7

    authors: Lin DX,Li X,Ye QW,Lin F,Li LL,Zhang QY

    更新日期:2011-11-01 00:00:00

  • Effect of miR-21 on renal fibrosis by regulating MMP-9 and TIMP1 in kk-ay diabetic nephropathy mice.

    abstract::MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression i...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9539-2

    authors: Wang J,Gao Y,Ma M,Li M,Zou D,Yang J,Zhu Z,Zhao X

    更新日期:2013-11-01 00:00:00

  • Surfactin induces apoptosis and G(2)/M arrest in human breast cancer MCF-7 cells through cell cycle factor regulation.

    abstract::Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-009-9065-4

    authors: Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

    更新日期:2009-01-01 00:00:00

  • Anti-proliferative Effect of Physcion on Human Gastric Cell Line via Inducing ROS-Dependent Apoptosis.

    abstract::In this study, the anti-proliferative effect of physcion, an anthraquinone derivative isolated and characterized from both terrestrial and marine sources, against human gastric cancer SGC-7901 cells was investigated and the underlying mechanisms were explored. Physcion reduced SGC-7901 cell viability in a dose- and ti...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-015-0674-9

    authors: Xiong Y,Ren L,Wang Z,Hu Z,Zhou Y

    更新日期:2015-11-01 00:00:00

  • Posterior fossa decompression combined with resection of the cerebellomedullary fissure membrane and expansile duraplasty: a radical and rational surgical treatment for Arnold-Chiari type I malformation.

    abstract::This study aims to introduce a new surgical procedure for the treatment of Arnold-Chiari type I malformation (ACM-1) and to compare its effectiveness with the techniques described in previous studies. We performed the following procedures: foramen magnum decompression combined with the removal of both the atlanto-occi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0135-x

    authors: Liang CJ,Dong QJ,Xing YH,Shan M,Wen LX,Qiang ZY,Ping ZQ,Tao PZ,Ping HX

    更新日期:2014-12-01 00:00:00

  • A possible role of Aspergillus niger mitochondrial cytochrome c in malachite green reduction under calcium chloride stress.

    abstract::In previous work, decolorization of malachite green (MG) was studied in Aspergillus niger in the presence and absence of calcium chloride stress. Decolorization took place within 24 h, and a signal transduction process that initiated MG decolorization was suggested to be involved. In the present study, further investi...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9661-1

    authors: Gomaa OM,Selim NS,Linz JE

    更新日期:2013-01-01 00:00:00

  • Comparative evaluation of two laparoscopic procedures for treating common bile duct stones.

    abstract::Cholesystolithiasis is often associated with common bile duct stones (CBDS). In order to assess the choice of surgery in terms of effectiveness and complications in the treatment of CBDS, we have compared three surgical procedures, viz., laparoscopic choledocholithotomy T-tube drainage (LCH-TD), laparoscopic cholecyst...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-010-9127-7

    authors: Gu AD,Li XN,Guo KX,Ma ZT

    更新日期:2011-04-01 00:00:00

  • Phosphatidylethanolamine from phosphatidylserine decarboxylase2 is essential for autophagy under cadmium stress in Saccharomyces cerevisiae.

    abstract::Cadmium (Cd) is a potent toxic element used in several industries and in the process contaminates air, soil, and water. Exposure of Saccharomyces cerevisiae to Cd increases the major phospholipids, and profound increase was observed in phosphatidylethanolamine (PE). In yeast, there are four different pathways contribu...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9667-8

    authors: Muthukumar K,Nachiappan V

    更新日期:2013-01-01 00:00:00

  • Redox buffer capacity of the cell: theoretical and experimental approach.

    abstract::Reactive oxygen species (ROS) are involved in a variety of biological phenomena, such as mutation, carcinogenesis, inflammation, aging, development, and signal transduction. Intracellular generation of ROS might lead to the activation of redox signaling or oxidative stress. Nonetheless, it is difficult to estimate whe...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-010-9090-3

    authors: Martinovich GG,Martinovich IV,Cherenkevich SN,Sauer H

    更新日期:2010-11-01 00:00:00

  • Mitochondrial P-glycoprotein ATPase contributes to insecticide resistance in the cotton bollworm, Helicoverpa armigera (Noctuidae: Lepidoptera).

    abstract::Cotton bollworm, Helicoverpa armigera, is one of the most damaging polyphagous pests worldwide, which has developed high levels of resistance to commonly applied insecticides. Mitochondrial P-glycoprotein (Pgp) was detected in the insecticide-resistant strain of H. armigera using C219 antibodies, and its possible role...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-9969-5

    authors: Akbar SM,Aurade RM,Sharma HC,Sreeramulu K

    更新日期:2014-09-01 00:00:00

  • Hypoxic Preconditioning Combined with Microbubble-Mediated Ultrasound Effect on MSCs Promote SDF-1/CXCR4 Expression and its Migration Ability: An In Vitro Study.

    abstract::Our objective is to investigate the promoting effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US) on the SDF-1/CXCR4 expression and the migration ability of mesenchymal stem cells (MSCs). Based on the uniform design, the parameters of MB-mediated US, such as the total treatment ti...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-015-0698-1

    authors: Li L,Wu S,Li P,Zhuo L,Gao Y,Xu Y

    更新日期:2015-12-01 00:00:00

  • Jak2 tyrosine kinase: a true jak of all trades?

    abstract::Discovered roughly 10 yr ago, Jak2 tyrosine kinase has emerged as a critical molecule in mammalian development, physiology, and disease. Here, we review the early history of Jak2 and its role in health and disease. We will also review its critical role in mediating cytokine-dependent signal transduction. Additionally,...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,评审

    doi:10.1385/cbb:41:2:207

    authors: Sandberg EM,Wallace TA,Godeny MD,VonDerLinden D,Sayeski PP

    更新日期:2004-01-01 00:00:00

  • Comparison of the Outcomes of Two Operational Methods Used for the Fixation of Calcaneal Fracture.

    abstract::This study was aimed to compare the outcomes of two operational methods used for the fixation of calcaneal fracture, the open reduction using a plate and the minimally invasive cannulated screw fixations. Thus, we attempted to find out as to which of these fixation regimens was therapeutically superior by assessing im...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12013-014-0436-0

    authors: Wang Q,Li X,Sun Y,Yan L,Xiong C,Wang J

    更新日期:2015-05-01 00:00:00

  • Theoretical and experimental investigation of calcium-contraction coupling in airway smooth muscle.

    abstract::We investigated theoretically and experimentally the Ca2+-contraction coupling in rat tracheal smooth muscle. [Ca2+]i, isometric contraction and myosin light chain (MLC) phosphorylation were measured in response to 1 mM carbachol. Theoretical modeling consisted in coupling a model of Ca2+-dependent MLC kinase (MLCK) a...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1385/CBB:46:3:233

    authors: Mbikou P,Fajmut A,Brumen M,Roux E

    更新日期:2006-01-01 00:00:00

  • Analysis of volatile organic compounds liberated and metabolised by human umbilical vein endothelial cells (HUVEC) in vitro.

    abstract::Gas chromatography with mass spectrometric detection combined with head-space needle trap extraction as the pre-concentration technique was applied to identify and quantify volatile organic compounds released or metabolised by human umbilical vein endothelial cells. Amongst the consumed species there were eight aldehy...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0201-4

    authors: Mochalski P,Theurl M,Sponring A,Unterkofler K,Kirchmair R,Amann A

    更新日期:2015-01-01 00:00:00

  • Influence of amino acids Shiff bases on irradiated DNA stability in vivo.

    abstract::To reveal protective role of the new Mn(II) complexes with Nicotinyl-L-Tyrosinate and Nicotinyl-L-Tryptophanate Schiff Bases against ionizing radiation. The DNA of the rats liver was isolated on 7, 14, and 30 days after X-ray irradiation. The differences between the DNA of irradiated rats and rats pre-treated with Mn(...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-013-9617-5

    authors: Karapetyan NH,Malakyan MH,Bajinyan SA,Torosyan AL,Grigoryan IE,Haroutiunian SG

    更新日期:2013-01-01 00:00:00

  • The significance and mechanism of propofol on treatment of ischemia reperfusion induced lung injury in rats.

    abstract::This study is aimed to investigate the efficacy and underlying the mechanism of propofol in treatment of ischemia reperfusion (IR)-induced lung injury in rats, providing a novel insight of therapeutic strategy for IR-induced lung injury. 120 healthy SD rats were selected and randomly divided into sham operation group,...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0088-0

    authors: Yang P,Yang N,Zhang X,Xu X

    更新日期:2014-12-01 00:00:00

  • Contribution of hydrogenase 2 to stationary phase H2 production by Escherichia coli during fermentation of glycerol.

    abstract::Escherichia coli has four hydrogenases (Hyd), three genes of which are encoded by the hya, hyb, and hyc operons. The proton-reducing and hydrogen-oxidizing activities of Hyd-2 (hyb) were analyzed in whole cells grown to stationary phase and cell extracts, respectively, during glycerol fermentation using novel double m...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-012-9458-7

    authors: Trchounian K,Soboh B,Sawers RG,Trchounian A

    更新日期:2013-05-01 00:00:00

  • Impact analysis of autoantibody level and NR2 antibody level in neuropsychiatric SLE treated by methylprednisolone combined with MTX and DXM intrathecal injection.

    abstract::The objective is to explore the clinical curative effects of methylprednisolone combined with MTX and DXM intrathecal injection in treating neuropsychiatric systemic lupus erythematosus (NPSLE) and its effects on autoantibody level and anti-N-methyl-D-aspartate receptor subtype NR2a/2b antibody (anti-NR2 antibody) lev...

    journal_title:Cell biochemistry and biophysics

    pub_type: 杂志文章

    doi:10.1007/s12013-014-0010-9

    authors: Wang J,Zhao Y,Zhang J,Lei H,Zhu G,Fu B

    更新日期:2014-11-01 00:00:00