Mechanical induction of BMP-7 in osteocyte blocks glucocorticoid-induced apoptosis through PI3K/AKT/GSK3β pathway.

abstract：:The objective of this study was to evaluate the protective effect of recombinant human brain natriuretic peptide (rhBNP) on endotoxin-induced acute kidney injury (AKI) in canine model of septic shock and its potential mechanisms. Dogs with endotoxin-induced septic shock were subjected to intravenous infusion of saline...

journal_title：Cell biochemistry and biophysics

authors： Li N,Jin HX,Song Z,Bai CZ,Cui Y,Gao Y

更新日期：2014-11-01 00:00:00

abstract：:Anions enter from the cytoplasm into the channel pore of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel not via a central pathway but via a single lateral portal or fenestration. High Cl- conductance is dependent on electrostatic attraction of cytoplasmic Cl- ions by four positively charged...

journal_title：Cell biochemistry and biophysics

authors： Linsdell P,Negoda A,Cowley EA,El Hiani Y

更新日期：2020-03-01 00:00:00

abstract：:Olfactory ensheathing cells (OECs) are of great interest for regenerative purposes since they are believed to aid axonal growth. With the view set on the strategies to achieve reconnection between neuronal structures, it is of great importance to characterize the behaviour of these cells on long thread-like structures...

journal_title：Cell biochemistry and biophysics

authors： Pérez-Garnés M,Martínez-Ramos C,Barcia JA,Escobar Ivirico JL,Gómez-Pinedo U,Vallés-Lluch A,Monleón Pradas M

更新日期：2013-01-01 00:00:00

abstract：:Curcumin possesses anti-cancer effects. In the current study, we tested the effect of curcumin on cell proliferation, viability, apoptosis, cell cycle phases, and activation of the PI3K/Akt pathway in the renal cell carcinoma (RCC) cell line RCC-949. We observed that cell proliferation and viability were markedly inhi...

journal_title：Cell biochemistry and biophysics

authors： Zhang H,Xu W,Li B,Zhang K,Wu Y,Xu H,Wang J,Zhang J,Fan R,Wei J

更新日期：2015-12-01 00:00:00

abstract：:Establishment of a detection platform for glioblastoma-dendritic cell (DC) vaccine preparation and to determine the efficacy of the vaccine in a clinical trial. Autologous glioblastoma-DC vaccine was prepared from a glioblast specimen procured from surgical resection. The specimen was used to enrich the vaccine with p...

journal_title：Cell biochemistry and biophysics

authors： Jie X,Hua L,Jiang W,Feng F,Feng G,Hua Z

更新日期：2012-01-01 00:00:00

abstract：:A fast-track clinical pathway is designed to streamline patient care delivery and maximize cost effectiveness. It has decreased postoperative length of stay (LOS) and hospital charges for many surgical procedures. However, data on clinical pathways after liver surgery are sparse. This study examined whether use of a f...

journal_title：Cell biochemistry and biophysics

authors： Lin DX,Li X,Ye QW,Lin F,Li LL,Zhang QY

更新日期：2011-11-01 00:00:00

abstract：:We aimed to understand the molecular mechanism underlying the incidence of Oxaliplatin resistance in colorectal cancer. The Oxaliplatin-resistant (OR) HT29 colorectal cell line was established by long-term exposure to Oxaliplatin. Cell viability and proliferation were determined by the 3-(4,5-dimethyl thiazol-2-yl)-2,...

journal_title：Cell biochemistry and biophysics

authors： Zhao Z,Zhang G,Li W

更新日期：2020-12-01 00:00:00

abstract：:Mechanics of cancer cells are directly linked to their metastatic potential, or ability to produce a secondary tumor at a distant site. Metastatic cells survive in the circulatory system in a non-adherent state, and can squeeze through barriers in the body. Such considerable structural changes in cells rely on rapid r...

journal_title：Cell biochemistry and biophysics

authors： Gal N,Weihs D

更新日期：2012-07-01 00:00:00

abstract：:Cotton bollworm, Helicoverpa armigera, is one of the most damaging polyphagous pests worldwide, which has developed high levels of resistance to commonly applied insecticides. Mitochondrial P-glycoprotein (Pgp) was detected in the insecticide-resistant strain of H. armigera using C219 antibodies, and its possible role...

journal_title：Cell biochemistry and biophysics

authors： Akbar SM,Aurade RM,Sharma HC,Sreeramulu K

更新日期：2014-09-01 00:00:00

abstract：:Many of the structural domains involved in Ca2+ channel (CACN) inactivation are also involved in determining their sensitivity to antagonist inhibition. We hypothesize that differences in inactivation properties and their structural determinants may suggest candidate domains as targets for the development of novel, se...

journal_title：Cell biochemistry and biophysics

authors： Cox RH,Kathrins M

更新日期：2006-01-01 00:00:00

abstract：:Herpes simplex virus (HSV) is one of the most common viruses infecting humans and animals. Cellular adhesion is increased in HSV and plays a role in pathogenesis of inflammatory response during this viral infection. In our study, we studied a potential role of glycyrrhizin in disrupting cellular adhesion in HSV. We is...

journal_title：Cell biochemistry and biophysics

authors： Huang W,Chen X,Li Q,Li P,Zhao G,Xu M,Xie P

更新日期：2012-01-01 00:00:00

abstract：:To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

journal_title：Cell biochemistry and biophysics

authors： Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

更新日期：2014-06-01 00:00:00

abstract：:The possibility that binuclear dinitrosyl iron complexes with glutathione and cysteine (DNIC-GSН and B-DNIC-Cys) have a strong cytotoxic effect on the growth of endometrioid tumours (EMT) in rats with surgically induced experimental endometriosis established in our previous studies has been supported with experimental...

journal_title：Cell biochemistry and biophysics

authors： Burgovа EN,Khristidis YI,Kurkov AV,Mikoyan VD,Shekhter AB,Adamyan LV,Timashev PS,Vanin AF

更新日期：2019-03-01 00:00:00

abstract：:The dynamic micromechanical and structural properties of single human red blood cells are studied using a combination of dual trap optical tweezers and confocal Raman spectroscopy. Such a combination permits us to show a direct relationship between the rheological properties and chemical structure conformation. The fr...

journal_title：Cell biochemistry and biophysics

authors： Raj S,Wojdyla M,Petrov D

更新日期：2013-04-01 00:00:00

abstract：:Structural organization of the cytoplasm by compartmentation is a well established fact for the eukaryotic cell. In prokaryotes, compartmentation is less obvious. Most prokaryotes do not need intracytoplasmic membranes to maintain their vital functions. This review, especially dealing with prokaryotes, will point out ...

journal_title：Cell biochemistry and biophysics

authors： Hoppert M,Mayer F

更新日期：1999-01-01 00:00:00

abstract：:Myocardium viability in ischemic heart failure (HF) may affect the effect of cardiac resynchronization therapy (CRT). We hypothesized that longitudinal strain of 2D-STE, which reflects myocardium viability, can predict the response to CRT in patients with ischemic HF. 2D-STE was performed in 42 patients with HF, 1 wee...

journal_title：Cell biochemistry and biophysics

authors： Ma CY,Liu S,Yang J,Tang L,Zhang LM,Li N,Yu B

更新日期：2014-09-01 00:00:00

abstract：:To investigate the effects of the HDMX polymorphism on sarcoma risk. Relevant studies were identified by searching the PubMed, Embase, and Web of Science databases. Data were extracted by two independent investigators. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated using a fixed-effects model to...

journal_title：Cell biochemistry and biophysics

authors： Xu H,Zhou P,Ti Y,Jia F

更新日期：2014-12-01 00:00:00

abstract：:Semaphorin4D (Sema4D) belongs to Semaphorins family and is secreted and membrane-bound protein. Its function on angiogenesis and axon regeneration makes it an ideal therapeutic target for spinal cord injury (SCI). Here we examined Sema4D expression profile by real-time PCR and western blot and found Sema4D was upregul...

journal_title：Cell biochemistry and biophysics

authors： Zhang HL,Wang J,Tang L

更新日期：2014-04-01 00:00:00

abstract：:We investigated theoretically and experimentally the Ca2+-contraction coupling in rat tracheal smooth muscle. [Ca2+]i, isometric contraction and myosin light chain (MLC) phosphorylation were measured in response to 1 mM carbachol. Theoretical modeling consisted in coupling a model of Ca2+-dependent MLC kinase (MLCK) a...

journal_title：Cell biochemistry and biophysics

authors： Mbikou P,Fajmut A,Brumen M,Roux E

更新日期：2006-01-01 00:00:00

abstract：:Cellular responses to external signals often reflect alterations in gene expression. The activation of cell surface hormone or growth factor receptors upon the binding of appropriate ligands mobilizes signal transduction cascades that can ultimately impact the activity of defined sets of transcription factors. The int...

journal_title：Cell biochemistry and biophysics

authors： DeFranco DB

更新日期：1999-01-01 00:00:00

abstract：:Peroxisomal and mitochondrial carnitine acetyltransferase (CAT; EC 2.3.1.7) isozymes are synthesized from the first and second ATG codons of the open reading frame of one gene, Candida tropicalis CAT. Primer extension analysis and RNase protection assay revealed that the peroxisomal CAT, initiating at the second AUG c...

journal_title：Cell biochemistry and biophysics

authors： Tanaka A,Ueda M

更新日期：2000-01-01 00:00:00

abstract：:The bis-retinoid N-retinyl-N-retinylidene ethanolamine (A2E) is formed as a byproduct of visual cycle in retinal pigment epithelium (RPE). It contributes to golden-yellow fluorescence of the age pigment lipofuscin, which accumulates in RPE. Lipofuscin can generate a variety of reactive oxygen species (ROS) upon blue-l...

journal_title：Cell biochemistry and biophysics

authors： Furso J,Zadlo A,Szewczyk G,Sarna TJ

更新日期：2020-12-01 00:00:00

abstract：:The functions of membrane proteins are highly dependent on their phospholipid environment. In this article, we have used a hydrophobic photolabeling method to study the noncovalent interactions between plasma membrane calcium pump (PMCA) and surrounding phospholipids. With this approach, we determined (1) the number o...

journal_title：Cell biochemistry and biophysics

authors： Villamil Giraldo AM,Castello PR,González Flecha FL,Delfino JM,Rossi JP

更新日期：2006-01-01 00:00:00

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:The aim of this study was to analyze the clinicopathologic significance of ERα protein that localized in the cell cytoplasm and/or cell membrane of human breast cancer and explore what kind of protein that the cytoplasm/membrane ERα belongs to. ERα expressions in 61 cases of breast cancer are detected by immunohistoch...

journal_title：Cell biochemistry and biophysics

authors： Li L,Wang Q,Lv X,Sha L,Qin H,Wang L,Li L

更新日期：2015-01-01 00:00:00

abstract：:The objective of this study was to analyze the enhancement patterns at dynamic gadolinium-enhanced T1-weighted MR imaging in patients of Hepatocellular Carcinoma (HCC) with associated Budd-Chiari syndrome (BCS). The MR imaging findings in 10 patients of HCC with associated BCS were compared to those of 32 other patien...

journal_title：Cell biochemistry and biophysics

authors： Yang C,Xu K,Zheng J,Ma P,Hu C,Li S,Rong Y,Lu X,Zhang Q,Zu M,Hua R,Zhang L

更新日期：2014-09-01 00:00:00

abstract：:Proper administration of antithrombotic and antiplatelet drugs after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) and renal insufficiency is a challenging task. In this study, we utilized Fondaparinux and Tirofiban (either separately or combined) to treat post-PCI patients wi...

journal_title：Cell biochemistry and biophysics

authors： Changjiang H,Jian Q,Yuan Z,Liang Y,Puqing L,Xiaolong G

更新日期：2015-12-01 00:00:00

abstract：:Gastrointestinal stromal tumors (GISTs) are defined as spindle cell and/or epithelioid tumors originated from interstitial Cajal cells or precursors in the digestive tract. This study was conducted to identify genes differing in expression between the gastric tumors and the adjacent non-cancerous mucosas in patients w...

journal_title：Cell biochemistry and biophysics

authors： Kou Y,Zhao Y,Bao C,Wang Q

更新日期：2015-06-01 00:00:00

abstract：:Curcumin is a yellow-orange dye widely used as a spice, food coloring and food preservative. It also exhibits a broad range of therapeutic effects against different disorders such as cancer, diabetes, or neurodegenerative diseases. As a compound insoluble in water curcumin accumulates in cell membranes and due to this...

journal_title：Cell biochemistry and biophysics

authors： Duda M,Cygan K,Wisniewska-Becker A

更新日期：2020-06-01 00:00:00

abstract：:The prevalence of cardiovascular disease (CVD) is increasing dramatically especially in developing countries like India. CVD is a leading cause of morbidity and mortality. There has been a growing awareness of the role of nutrients in the prevention of CVD. One specific recommendation in the battle against CVD is the ...

journal_title：Cell biochemistry and biophysics

authors： Cao Y,Lu L,Liang J,Liu M,Li X,Sun R,Zheng Y,Zhang P

更新日期：2015-05-01 00:00:00