Intracellular mechanics and activity of breast cancer cells correlate with metastatic potential.

abstract：:We have studied the mechanisms of NaCl transport in the mammalian proximal tubule. Studies of isolated brush-border membrane vesicles confirmed the presence of Na+-H+ exchange and identified Cl(-)-formate and Cl(-)-oxalate exchangers as possible mechanisms of uphill Cl- entry. We found that formate and oxalate each st...

journal_title：Cell biochemistry and biophysics

authors： Aronson PS

更新日期：2002-01-01 00:00:00

abstract：:Our objective was to explore the effects of miR-92a and miR-126 on myocardial apoptosis in mouse ischemia-reperfusion model and further investigate the underlying mechanisms. Eighteen Kunming mice were selected and randomly divided into sham operation group and ischemia-reperfusion group with nine mice in each group. ...

journal_title：Cell biochemistry and biophysics

authors： Jiang C,Ji N,Luo G,Ni S,Zong J,Chen Z,Bao D,Gong X,Fu T

更新日期：2014-12-01 00:00:00

abstract：:Synaptic glutamate receptors play a prominent role in the excitatory neurotransmission in the vertebrate central nervous system. Although elucidation of the functional properties of glutamate receptors using electrophysiologic analyses has yielded important information, methodological and technological limitations hav...

journal_title：Cell biochemistry and biophysics

authors： Vaithianathan T,Manivannan K,Kleene R,Bahr BA,Dey MP,Dityatev A,Suppiramaniam V

更新日期：2005-01-01 00:00:00

abstract：:The functions of membrane proteins are highly dependent on their phospholipid environment. In this article, we have used a hydrophobic photolabeling method to study the noncovalent interactions between plasma membrane calcium pump (PMCA) and surrounding phospholipids. With this approach, we determined (1) the number o...

journal_title：Cell biochemistry and biophysics

authors： Villamil Giraldo AM,Castello PR,González Flecha FL,Delfino JM,Rossi JP

更新日期：2006-01-01 00:00:00

abstract：:To investigate the effects of the HDMX polymorphism on sarcoma risk. Relevant studies were identified by searching the PubMed, Embase, and Web of Science databases. Data were extracted by two independent investigators. Odds ratios (ORs) and 95 % confidence intervals (CIs) were calculated using a fixed-effects model to...

journal_title：Cell biochemistry and biophysics

authors： Xu H,Zhou P,Ti Y,Jia F

更新日期：2014-12-01 00:00:00

abstract：:A rapid capillary electrophoresis method using carboxymethyl-β-cyclodextrin (CM-β-CD) as chiral selector was developed and validated for the enantiomeric purity determination of levamlodipine besylate bulk drug. Several parameters for were optimized for a satisfactory enantioresolution, including pH of background elec...

journal_title：Cell biochemistry and biophysics

authors： Qi Y,Zhang X

更新日期：2014-12-01 00:00:00

abstract：:Anions enter from the cytoplasm into the channel pore of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel not via a central pathway but via a single lateral portal or fenestration. High Cl- conductance is dependent on electrostatic attraction of cytoplasmic Cl- ions by four positively charged...

journal_title：Cell biochemistry and biophysics

authors： Linsdell P,Negoda A,Cowley EA,El Hiani Y

更新日期：2020-03-01 00:00:00

abstract：:Escherichia coli has four hydrogenases (Hyd), three genes of which are encoded by the hya, hyb, and hyc operons. The proton-reducing and hydrogen-oxidizing activities of Hyd-2 (hyb) were analyzed in whole cells grown to stationary phase and cell extracts, respectively, during glycerol fermentation using novel double m...

journal_title：Cell biochemistry and biophysics

authors： Trchounian K,Soboh B,Sawers RG,Trchounian A

更新日期：2013-05-01 00:00:00

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:Cadmium (Cd) is a potent toxic element used in several industries and in the process contaminates air, soil, and water. Exposure of Saccharomyces cerevisiae to Cd increases the major phospholipids, and profound increase was observed in phosphatidylethanolamine (PE). In yeast, there are four different pathways contribu...

journal_title：Cell biochemistry and biophysics

authors： Muthukumar K,Nachiappan V

更新日期：2013-01-01 00:00:00

abstract：:Depression is a common emotional disorder associated with increased risk of suicide and rate of disability. In this double-blinded control study, we tested the efficacy of modified electroconvulsive therapy (MECT) in patients with treatment resistant depression (TRD) using the Hamilton Depression Rating Scale for Depr...

journal_title：Cell biochemistry and biophysics

authors： Lin Z,He H,Zhang C,Wang Z,Jiang M,Li Q,Lan X,Zhang M,Huang X

更新日期：2015-04-01 00:00:00

abstract：:The role of bone morphogenetic protein 4 (BMP4) in gliomas is not clear. We hypothesized that BMP4 inhibits proliferation in the brain glioma cell line U251 through a signaling pathway involving BMP4 and the mothers against decapentaplegic homolog 4 (SMAD4) protein. We exposed U251 cells to Adriamycin (1 g) for 48 h; ...

journal_title：Cell biochemistry and biophysics

authors： Liu B,Tian D,Yi W,Wu L,Cai Q,Dong H,Shen H,Ji B,Wang L,Zhang S,Ruan D,Chen Q

更新日期：2010-11-01 00:00:00

abstract：:Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

journal_title：Cell biochemistry and biophysics

authors： Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

更新日期：2009-01-01 00:00:00

abstract：:Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

journal_title：Cell biochemistry and biophysics

authors： Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

更新日期：2014-09-01 00:00:00

abstract：:Leptin is a protein hormone which plays a critical role in the regulation of both body-weight through reducing food intake and stimulating energy expenditure. Several polymorphisms in leptin gene (LEP), which encodes for leptin, have been described. However, its association with obesity is still controversial. Therefo...

journal_title：Cell biochemistry and biophysics

authors： Sahin DS,Tumer C,Demir C,Celik MM,Celik M,Ucar E,Gunesacar R

更新日期：2013-03-01 00:00:00

abstract：:Zirconia-based ceramics is widely used in dentistry. Different compositions of ceramics have different features. Our self-renovated ceramics become more machinable without scarifying its dental restoration properties after adjusting ratio of lanthanum phosphate (LaPO4)/yttrium oxide (Y2O3). In order to evaluate its sa...

journal_title：Cell biochemistry and biophysics

authors： Hua N,Zhu H,Zhuang J,Chen L

更新日期：2014-12-01 00:00:00

abstract：:The objective of this study was to assess the clinical and histopathological relationship between pulmonary fibrosis and type 1 diabetes. We examined clinical pulmonary function parameters and transbronchial lung biopsies to assess associated histopathological changes in 12 type 1 diabetic patients presenting with dys...

journal_title：Cell biochemistry and biophysics

authors： Hu Y,Ma Z,Guo Z,Zhao F,Wang Y,Cai L,Yang J

更新日期：2014-11-01 00:00:00

abstract：:Insulin, the major secreted product of the beta-cells of the islets of Langerhans, is initially synthesized as a precursor (preproinsulin), from which the mature hormone is excised by a series of proteolytic cleavages. This review provides a personal narrative of some of the key research projects leading to the identi...

journal_title：Cell biochemistry and biophysics

authors： Davidson HW

更新日期：2004-01-01 00:00:00

abstract：:Fibroblasts can be reprogrammed by ectopic expression of reprogramming factors to yield induced pluripotent stem (iPS) cells that are capable of transdifferentiating into diverse types of somatic cell lines. In this study, we examined if functional cardiomyocytes (CMs) can be produced from mouse cardiac fibroblasts (C...

journal_title：Cell biochemistry and biophysics

authors： Jiang B,Dong H,Li Q,Yu Y,Zhang Z,Zhang Y,Wang G,Zhang Z

更新日期：2013-06-01 00:00:00

abstract：:Mutations of the retinoblastoma tumor suppressor, pRb, or its cyclin-cyclin-dependent kinase (CDK) regulatory kinases or CDK inhibitors, allows unrestrained E2F activity, leading to unregulated cell cycle progression. However, overexpression of E2F-1 also sensitizes cells to apoptosis, suggesting that targeting this p...

journal_title：Cell biochemistry and biophysics

authors： Nip J,Hiebert SW

更新日期：2000-01-01 00:00:00

abstract：:cDNAs encoding two PDE-3 or cyclic GMP-inhibited (cGI) cyclic nucleotide phosphodiesterase (PDE) isoforms, RPDE-3B (RcGIP1) and HPDE-3A (HcGIP2), were cloned from rat (R) adipose tissue and human (H) heart cDNA libraries. Deletion and N- and C-terminal truncation mutants were expressed in Escherichia coli in order to ...

journal_title：Cell biochemistry and biophysics

authors： He R,Komas N,Ekholm D,Murata T,Taira M,Hockman S,Degerman E,Manganiello VC

更新日期：1998-01-01 00:00:00

abstract：:Pro-domain of a cysteine cathepsin contains a highly conserved Ex2Rx2Fx2Nx3Ix3N (ERFNIN) motif. The zymogen structure of cathepsins revealed that the Arg(R) residue of the motif is a central residue of a salt-bridge/H-bond network, stabilizing the scaffold of the pro-domain. Importance of the arginine is also demonstr...

journal_title：Cell biochemistry and biophysics

authors： Aich P,Biswas S

更新日期：2018-06-01 00:00:00

abstract：:Behcet's disease (BD) accompanied by intestinal involvement is called intestinal BD. Although recent studies have attained positive feedback with the administration of anti-TNF-α agents in patients with BD, only a few reports on the study of etanercept in intestinal BD have been found. In this study, 35 cases of intes...

journal_title：Cell biochemistry and biophysics

authors： Ma D,Zhang CJ,Wang RP,Wang L,Yang H

更新日期：2014-07-01 00:00:00

abstract：:This study describes clinical experience and curative effect of radiophotographically controlled nasointestinal intubation in the treatment of small intestine arrangement in recurrent postoperative adhesive ileus. A 300-cm-long nasointestinal tube was installed into the jejunum through the nasal cavity under radiophot...

journal_title：Cell biochemistry and biophysics

authors： Li RH,Li DC,Lv XP,Quan B

更新日期：2015-06-01 00:00:00

abstract：:The objective of this study is to investigate the roles of acteoside (ACT) in cells with oxygen-glucose deprivation and reoxygenation (OGD/R)-induced injury and the underlying mechanisms. The differentially expressed genes (DEGs) in rats with middle cerebral artery occlusion were identified using GSE61616 data set. Ky...

journal_title：Cell biochemistry and biophysics

authors： Wu W,Wu G,Cao D

更新日期：2021-01-13 00:00:00

abstract：:Establishment of a detection platform for glioblastoma-dendritic cell (DC) vaccine preparation and to determine the efficacy of the vaccine in a clinical trial. Autologous glioblastoma-DC vaccine was prepared from a glioblast specimen procured from surgical resection. The specimen was used to enrich the vaccine with p...

journal_title：Cell biochemistry and biophysics

authors： Jie X,Hua L,Jiang W,Feng F,Feng G,Hua Z

更新日期：2012-01-01 00:00:00

abstract：:The study analyzed how enteral ecoimmunonutrition, which comprises probiotics, glutamine, fish oil, and Enteral Nutritional Suspension (TPF), can impact on the enteral permeability and serum Ghrelin activity in severe cerebral stroke patients with lung infection. Among 190 severe cerebral stroke patients with toleranc...

journal_title：Cell biochemistry and biophysics

authors： Xu XD,Shao F

更新日期：2015-01-01 00:00:00

abstract：:Myocardium viability in ischemic heart failure (HF) may affect the effect of cardiac resynchronization therapy (CRT). We hypothesized that longitudinal strain of 2D-STE, which reflects myocardium viability, can predict the response to CRT in patients with ischemic HF. 2D-STE was performed in 42 patients with HF, 1 wee...

journal_title：Cell biochemistry and biophysics

authors： Ma CY,Liu S,Yang J,Tang L,Zhang LM,Li N,Yu B

更新日期：2014-09-01 00:00:00

abstract：:Recent studies designed to assess the relationship between aortic compliance and heterogeneity of heart electrical activity has shown that hypertrophy aggravates repolarization disturbances in the myocardium. Numerous mechanisms of electrical instability and inhomogeneity associated with left ventricular hypertrophy a...

journal_title：Cell biochemistry and biophysics

authors： Gao C,Yang D

更新日期：2014-07-01 00:00:00

abstract：:Despite the improvements in chemotherapy, about 60 % of acute myeloid leukemia (AML) remission patients still relapse. Leukemic stem cells (LSCs) are the main causes for the relapse and refractory. T cell immunoglobulin mucin-3 (TIM-3), a specific surface molecule expressed on LSCs in most types of AML, is a candidate...

journal_title：Cell biochemistry and biophysics

authors： Gao L,Yu S,Zhang X

更新日期：2014-09-01 00:00:00