Electrical inhomogeneity in left ventricular hypertrophy.

Abstract:

:Recent studies designed to assess the relationship between aortic compliance and heterogeneity of heart electrical activity has shown that hypertrophy aggravates repolarization disturbances in the myocardium. Numerous mechanisms of electrical instability and inhomogeneity associated with left ventricular hypertrophy are now under investigation. Most of the studies have been found to be focused on ventricular Gradient, QT dispersion, amplitudes of isointegral maps during ventricular repolarization, abnormally low-QRST areas, dispersion of the QT interval, and spatial QRS-T(angle). These studies point to marked repolarization abnormalities in left ventricular hypertrophy and the dispersion of the QT interval as a valuable index for inhomogeneity of repolarization and the subsequent heart rate variability. The heart rate-corrected QT dispersion and QT apex dispersion seem to be significantly longer in the patients with left ventricular hypertrophy than in normal individuals. The review study has also identified QRST isointegral map as a valuable technique in assessment of the electro-cardiac events in LVH.

journal_name

Cell Biochem Biophys

authors

Gao C,Yang D

doi

10.1007/s12013-014-9850-6

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

399-404

issue

3

eissn

1085-9195

issn

1559-0283

journal_volume

69

pub_type

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