Cell contraction caused by microtubule disruption is accompanied by shape changes and an increased elasticity measured by scanning acoustic microscopy.

abstract：:Escherichia coli has four hydrogenases (Hyd), three genes of which are encoded by the hya, hyb, and hyc operons. The proton-reducing and hydrogen-oxidizing activities of Hyd-2 (hyb) were analyzed in whole cells grown to stationary phase and cell extracts, respectively, during glycerol fermentation using novel double m...

journal_title：Cell biochemistry and biophysics

authors： Trchounian K,Soboh B,Sawers RG,Trchounian A

更新日期：2013-05-01 00:00:00

abstract：:The simultaneous determination of adhesion and deformability parameters of erythrocytes was carried out through a microfluidic device, which uses an inverted optical microscope with new image acquisition and analysis technologies. Also, an update of the models describing erythrocyte adhesion and deformation was propos...

journal_title：Cell biochemistry and biophysics

authors： Londero CM,Riquelme BD

更新日期：2020-11-07 00:00:00

abstract：:Human copper transporter 1 (hCTR1) is the major high affinity copper influx transporter in mammalian cells that also mediates uptake of the cancer chemotherapeutic agent cisplatin. A low resolution structure of hCTR1 determined by cryoelectron microscopy was recently published. Several protein structure simulation tec...

journal_title：Cell biochemistry and biophysics

authors： Tsigelny IF,Sharikov Y,Greenberg JP,Miller MA,Kouznetsova VL,Larson CA,Howell SB

更新日期：2012-07-01 00:00:00

abstract：:A rapid and sensitive liquid chromatography-tandem mass spectrometry assay (LC-MS/MS) with electrospray ionization was developed and validated for the quantitative determination of the concentration of methotrexate (MTX) enantiomers in intracellular and extracellular fluids of HepG2 cells. The analytes were extracted ...

journal_title：Cell biochemistry and biophysics

authors： Wang R,Guo L,Xie H,Zhang J,Li X,Li W,Wang J,Wu X,Jia Z

更新日期：2013-01-01 00:00:00

abstract：:Spectral karyotyping is a novel technique for chromosome analysis that has been developed based on the approach of the fluorescence in situ hybridization technique. Spectral karyotyping makes it feasible to diagnose a variety of diseases, because of its technology in painting each of the 24 human chromosomes with diff...

journal_title：Cell biochemistry and biophysics

authors： Imataka G,Arisaka O

更新日期：2012-01-01 00:00:00

abstract：:Epidemiologic and experimental studies suggest that dietary fatty acids influence the development and progression of breast cancer. However, no clear data are present in literature that could demonstrate how n - 3 PUFA can interfere with breast cancer growth. It is suggested that these fatty acids might change the str...

journal_title：Cell biochemistry and biophysics

authors： Corsetto PA,Cremona A,Montorfano G,Jovenitti IE,Orsini F,Arosio P,Rizzo AM

更新日期：2012-09-01 00:00:00

abstract：:Neural stem cells (NSCs) have widely been used in the treatment of human neurological disorders as cell therapy via intracerebral or intraventricular infusion. However, the migration mechanism required for NSCs homing and recruitment remains to be elucidated. Recently, SDF-1/CXCR4 axis was shown to be responsible for ...

journal_title：Cell biochemistry and biophysics

authors： Xue L,Wang J,Wang W,Yang Z,Hu Z,Hu M,Ding P

更新日期：2014-12-01 00:00:00

abstract：:Elevated blood pressure is regarded as an independent risk factor for cardiovascular diseases and diabetes. We examined the relation between hematocrit and pre-hypertension as well as the effect of sex, obesity, fasting glucose, and lipids in Chinese adults. The study samples were from a community-based health examina...

journal_title：Cell biochemistry and biophysics

authors： Liu X,Liang J,Qiu Q,Zhu Y,Sun Y,Ying P,Teng F,Wang Y,Qi L

更新日期：2015-03-01 00:00:00

abstract：:The present study aimed at detecting DNA damage and fragmentation as well as histone acetylation depending on oxidative stress caused by CCl4 intoxication. Also, the protective role of N-acetyl cysteine, a precursor for GSH, in DNA damage is investigated. Sixty rats were used in this study. In order to induce liver to...

journal_title：Cell biochemistry and biophysics

authors： Aksit H,Bildik A

更新日期：2014-11-01 00:00:00

abstract：:The mechanism of induction of cardiomyocyte (CM) dedifferentiation, as seen in chronic hibernating myocardium, is largely unknown. Recently, a cellular model was proposed consisting of long-term cocultures of adult rabbit CMs and cardiac fibroblasts in which typical structural characteristics of hibernation-like dedif...

journal_title：Cell biochemistry and biophysics

authors： Driesen RB,Verheyen FK,Dispersyn GD,Thoné F,Lenders MH,Ramaekers FC,Borgers M

更新日期：2006-01-01 00:00:00

abstract：:Our objective is to investigate the promoting effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US) on the SDF-1/CXCR4 expression and the migration ability of mesenchymal stem cells (MSCs). Based on the uniform design, the parameters of MB-mediated US, such as the total treatment ti...

journal_title：Cell biochemistry and biophysics

authors： Li L,Wu S,Li P,Zhuo L,Gao Y,Xu Y

更新日期：2015-12-01 00:00:00

abstract：:Mechanical loading is known to promote osteocyte survival, whereas glucocorticoid treatment results in osteocyte apoptosis. Here, we report that BMP-7, which was secreted by osteocyte in response to mechanical loading, exerts anti-apoptotic effect against dexamethasone-induced apoptosis of osteocytes. We further show ...

journal_title：Cell biochemistry and biophysics

authors： Wang Z,Guo J

更新日期：2013-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) is one of the most common viruses infecting humans and animals. Cellular adhesion is increased in HSV and plays a role in pathogenesis of inflammatory response during this viral infection. In our study, we studied a potential role of glycyrrhizin in disrupting cellular adhesion in HSV. We is...

journal_title：Cell biochemistry and biophysics

authors： Huang W,Chen X,Li Q,Li P,Zhao G,Xu M,Xie P

更新日期：2012-01-01 00:00:00

abstract：:Apoptosis of endothelial cells related to homocysteine (Hcy) has been reported in several studies. In this study, we evaluated whether reactive oxygen species (ROS)-producing signaling pathways contribute to Hcy-induced apoptosis induction, with specific emphasis on NADPH oxidases. Human umbilical vein endothelial cel...

journal_title：Cell biochemistry and biophysics

authors： Sipkens JA,Hahn N,van den Brand CS,Meischl C,Cillessen SA,Smith DE,Juffermans LJ,Musters RJ,Roos D,Jakobs C,Blom HJ,Smulders YM,Krijnen PA,Stehouwer CD,Rauwerda JA,van Hinsbergh VW,Niessen HW

更新日期：2013-11-01 00:00:00

abstract：:The purpose of the study is to evaluate the effectiveness and safety of transarterial chemoembolization (TACE) with pingyangmycin-lipiodol emulsion for the treatment of symptomatic giant hepatic haemangioma. Four hospitals (The Second Hospital of Shandong University, Qilu Hospital of Shandong University, Shandong Prov...

journal_title：Cell biochemistry and biophysics

authors： Li Y,Jia Y,Li S,Wang W,Wang Z,Wang Y,Liu B,Wang W,Chang H,Li Z

更新日期：2015-11-01 00:00:00

abstract：:We investigated theoretically and experimentally the Ca2+-contraction coupling in rat tracheal smooth muscle. [Ca2+]i, isometric contraction and myosin light chain (MLC) phosphorylation were measured in response to 1 mM carbachol. Theoretical modeling consisted in coupling a model of Ca2+-dependent MLC kinase (MLCK) a...

journal_title：Cell biochemistry and biophysics

authors： Mbikou P,Fajmut A,Brumen M,Roux E

更新日期：2006-01-01 00:00:00

abstract：:Semaphorin4D (Sema4D) belongs to Semaphorins family and is secreted and membrane-bound protein. Its function on angiogenesis and axon regeneration makes it an ideal therapeutic target for spinal cord injury (SCI). Here we examined Sema4D expression profile by real-time PCR and western blot and found Sema4D was upregul...

journal_title：Cell biochemistry and biophysics

authors： Zhang HL,Wang J,Tang L

更新日期：2014-04-01 00:00:00

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:We aimed to understand the molecular mechanism underlying the incidence of Oxaliplatin resistance in colorectal cancer. The Oxaliplatin-resistant (OR) HT29 colorectal cell line was established by long-term exposure to Oxaliplatin. Cell viability and proliferation were determined by the 3-(4,5-dimethyl thiazol-2-yl)-2,...

journal_title：Cell biochemistry and biophysics

authors： Zhao Z,Zhang G,Li W

更新日期：2020-12-01 00:00:00

abstract：:To investigate if the 12-lead resting electrocardiogram (ECG) is a predictor of left ventricular (LV) functional recovery after revascularization of chronic total coronary artery occlusions (CTO). Revascularization was performed in 58 CTO patients who had impaired regional wall motion. The 12-lead resting ECG was used...

journal_title：Cell biochemistry and biophysics

authors： Yue W,Wang G,Zhang X,Chen B,Wang X,Huangfu F,Jia R

更新日期：2014-09-01 00:00:00

abstract：:The objective of this study was to analyze the enhancement patterns at dynamic gadolinium-enhanced T1-weighted MR imaging in patients of Hepatocellular Carcinoma (HCC) with associated Budd-Chiari syndrome (BCS). The MR imaging findings in 10 patients of HCC with associated BCS were compared to those of 32 other patien...

journal_title：Cell biochemistry and biophysics

authors： Yang C,Xu K,Zheng J,Ma P,Hu C,Li S,Rong Y,Lu X,Zhang Q,Zu M,Hua R,Zhang L

更新日期：2014-09-01 00:00:00

abstract：:By using a functional approach of reconstituting detergent-solubilized membrane proteins into liposomes and following their function in patch-clamp experiments, we identified a novel mechanosensitive (MS) channel in the thermophilic cell wall-less archaeon Thermoplasma volcanium. Sodium dodecyl sulfate polyacrylamide ...

journal_title：Cell biochemistry and biophysics

authors： Kloda A,Martinac B

更新日期：2001-01-01 00:00:00

abstract：:H5N1 is a subtype of the influenza A virus that can cause disease in humans and many other animal species. Oseltamivir (Tamiflu) is a potent and selective antiviral drug employed to fight the flu virus in infected individuals by inhibiting neuraminidase (NA), a flu protein responsible for the release and spread of the...

journal_title：Cell biochemistry and biophysics

authors： Karthick V,Ramanathan K

更新日期：2014-03-01 00:00:00

abstract：:This study explored the effect of a first aid model employing two nurses on the efficient rescue operation time and the efficient resuscitation time for major burn patients. A two-nurse model of first aid was designed for major burn patients. The model includes a division of labor between the first aid nurses and the ...

journal_title：Cell biochemistry and biophysics

authors： Wu W,Shi K,Jin Z,Liu S,Cai D,Zhao J,Chi C,Yu J

更新日期：2015-03-01 00:00:00

abstract：:The remarkable ability of living cells to sense, process, and respond to mechanical stimuli in their environment depends on the rapid and efficient interconversion of mechanical and chemical energy at specific times and places within the cell. For example, application of force to cells leads to conformational changes ...

journal_title：Cell biochemistry and biophysics

authors： Lele TP,Kumar S

更新日期：2007-01-01 00:00:00

abstract：:A number of case-control studies have been conducted to investigate the relationship between the ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms and risk of coronary heart disease (CHD). However, the results have been inconclusive. The purpose of the present study is to investigate whether this polymorp...

journal_title：Cell biochemistry and biophysics

authors： Liu N,Hou M,Ren W,Cao J,Wu H,Zhou W

更新日期：2015-01-01 00:00:00

abstract：:Many of the structural domains involved in Ca2+ channel (CACN) inactivation are also involved in determining their sensitivity to antagonist inhibition. We hypothesize that differences in inactivation properties and their structural determinants may suggest candidate domains as targets for the development of novel, se...

journal_title：Cell biochemistry and biophysics

authors： Cox RH,Kathrins M

更新日期：2006-01-01 00:00:00

abstract：:Although As2O3 (ATO) has been recommended as the front-line agent for treatment of acute promyelocytic leukemia (APL), particularly for relapsed or refractory APL, it has been associated with profound toxicity. Icariin is a natural compound with activity against a variety of cancers. This study was designed to investi...

journal_title：Cell biochemistry and biophysics

authors： Wang Z,Zhang H,Dai L,Song T,Li P,Liu Y,Wang L

更新日期：2015-09-01 00:00:00

abstract：:Objective of this article is to construct and characterize a three-layered small-caliber, artificial vascular stent. The outer layer of the stent consisted of small intestine submucosa (SIS), the middle layer was the polydioxanone (PDS) vascular stents, and the inner layer. The SIS and PDS were attached with 8-0 PDS t...

journal_title：Cell biochemistry and biophysics

authors： You Q,Wang F,Duan L,Du X,Xiao M,Shen Z

更新日期：2010-05-01 00:00:00

abstract：:We performed a meta-analysis to compare therapeutic outcome/safety of drug-eluting stent (DES) and conventional in-stent restenosis (ISR) treatments. We browsed through large volume of clinical data by searching MEDLINE, EMBASE, Cochrane central register of controlled trials, and EBSCO databases. In this study, 11 ran...

journal_title：Cell biochemistry and biophysics

authors： Sun Y,Li L,Su Q,Lu Y

更新日期：2014-01-01 00:00:00