Effects of Phyllanthus sellowianus Müll Arg. extracts on the rheological properties of human erythrocytes.

abstract：:Severe acute pancreatitis (SAP) is a common acute abdominal disease. This study was designed to investigate the preventive effects of curcumin on SAP and its possible mechanism of action. We observed increased volume of ascites, serum AMY, IL-6, and TNF-α levels, and expression of TLR-4 and NF-κB mRNA and protein in a...

journal_title：Cell biochemistry and biophysics

authors： Zhong K

更新日期：2015-09-01 00:00:00

abstract：:Na,K-ATPase (EC 3.6.1.37, Na,K-ATPase) is a fundamental vital membrane transport and receptor system which, after biosynthesis, is exported to the plasma membrane in inside-out vesicles. Na,K-ATPase can be extracted form the natural membrane and inserted into artificially formed phosphatidylcholine vesicles (liposomes...

journal_title：Cell biochemistry and biophysics

authors： Anner BM,Volet B

更新日期：1999-01-01 00:00:00

abstract：:Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds. This study was designed to evaluate the cardioprotec...

journal_title：Cell biochemistry and biophysics

authors： Adluri RS,Thirunavukkarasu M,Zhan L,Maulik N,Svennevig K,Bagchi M,Maulik G

更新日期：2013-11-01 00:00:00

abstract：:Diabetic cardiomyopathy is a leading cause of morbidity and mortality, and Insulin2 mutant (Ins2+/-) Akita is a genetic mice model of diabetes relevant to humans. Dicer, miRNAs, and inflammatory cytokines are associated with heart failure. However, the differential expression of miRNAs, dicer, and inflammatory molecul...

journal_title：Cell biochemistry and biophysics

authors： Chavali V,Tyagi SC,Mishra PK

更新日期：2014-01-01 00:00:00

abstract：:Skin fibrosis is one of the major features of scleroderma. WNT/β-catenin signaling is associated with the progression of skin fibrosis. In this study, we aimed to determine the effect of icaritin (IT), a natural compound, on scleroderma-related skin fibrosis and its mechanisms. We found that IT could reduce the expres...

journal_title：Cell biochemistry and biophysics

authors： Li M,Liu Q,He S,Kong X,Lin J,Huang Y,Wu W,Wu J

更新日期：2020-10-30 00:00:00

abstract：:The calcium channel gamma subunits comprise an eight-member protein family that share a common topology consisting of four transmembrane domains and intracellular N- and C-termini. Although the first gamma subunit was identified as an auxiliary subunit of a voltage-dependent calcium channel, a review of phylogenetic, ...

journal_title：Cell biochemistry and biophysics

authors： Chen RS,Deng TC,Garcia T,Sellers ZM,Best PM

更新日期：2007-01-01 00:00:00

abstract：:Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare form of primary liver cancer (PLC). It is difficult to make a correct preoperative diagnosis of cHCC-CC because of the lack of special features of the disease. We here present a case of a 68-year-old man who presented with fluctuant fever, ch...

journal_title：Cell biochemistry and biophysics

authors： E C,Xie Y,Yang Y,Ji D,Li W,Zhang X

更新日期：2014-05-01 00:00:00

abstract：:Ezrin is overexpressed in a variety of neoplastic cells and is involved in the later stages of tumor progression and metastasis. The present study investigated the expression and functional significance of ezrin in human brain astrocytoma. Ezrin expression was examined in specimens from healthy human brains (10 autops...

journal_title：Cell biochemistry and biophysics

authors： Mao J,Yuan XR,Xu SS,Jiang XC,Zhao XT

更新日期：2013-01-01 00:00:00

abstract：:Bortezomib is effective in the therapy of multiple myeloma (MM), but causes infections that are different from those associated with conventional chemotherapy. It is important to identify the risk factors that facilitate infections associated with bortezomib therapy. In the present report, we sought to (1) define the ...

journal_title：Cell biochemistry and biophysics

authors： Li J,Li Y,Huang B,Zheng D,Chen M,Zhou Z

更新日期：2015-01-01 00:00:00

abstract：:A recently developed method for surface modification, layer-by-layer (LbL) assembly, has been applied to silicone, and its ability to encourage endothelial cell growth and control cell growth patterns has been examined. The surfaces studied consisted of a precursor, with alternating cationic polyethyleneimine (PEI) an...

journal_title：Cell biochemistry and biophysics

authors： Ai H,Lvov YM,Mills DK,Jennings M,Alexander JS,Jones SA

更新日期：2003-01-01 00:00:00

abstract：:Mutations of the retinoblastoma tumor suppressor, pRb, or its cyclin-cyclin-dependent kinase (CDK) regulatory kinases or CDK inhibitors, allows unrestrained E2F activity, leading to unregulated cell cycle progression. However, overexpression of E2F-1 also sensitizes cells to apoptosis, suggesting that targeting this p...

journal_title：Cell biochemistry and biophysics

authors： Nip J,Hiebert SW

更新日期：2000-01-01 00:00:00

abstract：:Nano-drug delivery systems have proven to be an efficient formulation tool to overcome the challenges with current antibiotics therapy and resistance. A series of pH-responsive lipid molecules were designed and synthesized for future liposomal formulation as a nano-drug delivery system for vancomycin at the infection ...

journal_title：Cell biochemistry and biophysics

authors： Ahmed S,Vepuri SB,Jadhav M,Kalhapure RS,Govender T

更新日期：2018-06-01 00:00:00

abstract：:MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression i...

journal_title：Cell biochemistry and biophysics

authors： Wang J,Gao Y,Ma M,Li M,Zou D,Yang J,Zhu Z,Zhao X

更新日期：2013-11-01 00:00:00

abstract：:Apoptosis of endothelial cells related to homocysteine (Hcy) has been reported in several studies. In this study, we evaluated whether reactive oxygen species (ROS)-producing signaling pathways contribute to Hcy-induced apoptosis induction, with specific emphasis on NADPH oxidases. Human umbilical vein endothelial cel...

journal_title：Cell biochemistry and biophysics

authors： Sipkens JA,Hahn N,van den Brand CS,Meischl C,Cillessen SA,Smith DE,Juffermans LJ,Musters RJ,Roos D,Jakobs C,Blom HJ,Smulders YM,Krijnen PA,Stehouwer CD,Rauwerda JA,van Hinsbergh VW,Niessen HW

更新日期：2013-11-01 00:00:00

abstract：:Our objective is to investigate the promoting effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US) on the SDF-1/CXCR4 expression and the migration ability of mesenchymal stem cells (MSCs). Based on the uniform design, the parameters of MB-mediated US, such as the total treatment ti...

journal_title：Cell biochemistry and biophysics

authors： Li L,Wu S,Li P,Zhuo L,Gao Y,Xu Y

更新日期：2015-12-01 00:00:00

abstract：:The remarkable ability of living cells to sense, process, and respond to mechanical stimuli in their environment depends on the rapid and efficient interconversion of mechanical and chemical energy at specific times and places within the cell. For example, application of force to cells leads to conformational changes ...

journal_title：Cell biochemistry and biophysics

authors： Lele TP,Kumar S

更新日期：2007-01-01 00:00:00

abstract：:To evaluate the correlation between CT perfusion parameters and tumor angiogenesis, expression of VEGF is implanted in VX2 lung tumor. VX2 tumor cells were injected in 15 healthy New Zealand rabbits. After 20 days, tumors with diameter over 7 mm were scanned with 16 row spiral CT. Using Software Perfusion 3, blood flo...

journal_title：Cell biochemistry and biophysics

authors： Ling S,Deng D,Mo Y,Zhang X,Guan X,Wei Q

更新日期：2014-09-01 00:00:00

abstract：:Human salivary aldehyde dehydrogenase (hsALDH) enzyme appears to be the first line of defense in the body against exogenous toxic aldehydes. However till date much work has not been done on this important member of the ALDH family. In this study, we have purified hsALDH to homogeneity by diethylaminoethyl-cellulose (D...

journal_title：Cell biochemistry and biophysics

authors： Alam MF,Laskar AA,Choudhary HH,Younus H

更新日期：2016-09-01 00:00:00

abstract：:The mechanism of induction of cardiomyocyte (CM) dedifferentiation, as seen in chronic hibernating myocardium, is largely unknown. Recently, a cellular model was proposed consisting of long-term cocultures of adult rabbit CMs and cardiac fibroblasts in which typical structural characteristics of hibernation-like dedif...

journal_title：Cell biochemistry and biophysics

authors： Driesen RB,Verheyen FK,Dispersyn GD,Thoné F,Lenders MH,Ramaekers FC,Borgers M

更新日期：2006-01-01 00:00:00

abstract：:There is an emergent need for improving the microsurgical technique of variant arterial anastomosis to reduce the often seen surgery-related complications. We describe in this article our experience in improving this technique, in 73 living donor liver grafts (64 right lobes, 9 left lobes) in patients with end-stage l...

journal_title：Cell biochemistry and biophysics

authors： Liang Y,Ye S,Shi X,Ji W,Duan W,Luo Y,Dong J

更新日期：2013-03-01 00:00:00

abstract：:The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we ...

journal_title：Cell biochemistry and biophysics

authors： Gopalakrishnan C,Kamaraj B,Purohit R

更新日期：2014-12-01 00:00:00

abstract：:Hip fracture is a kind of osteoporotic fractures in elderly patients. Its important monitoring indicator is to measure bone mineral density (BMD) using DXA. The stress characteristics and material distribution in different parts of the bones can be well simulated by three-dimensional finite element analysis. Our previ...

journal_title：Cell biochemistry and biophysics

authors： Lin ZL,Li PF,Pang ZH,Zheng XH,Huang F,Xu HH,Li QL

更新日期：2015-11-01 00:00:00

abstract：:Although aggressive therapeutic regimen has been applied in the treatment of Glioblastoma (GBM), the prognosis of patients with GBM remains poor. Preclinical studies have demonstrated the efficacy of Suntinib in GBM both in vitro and in vivo. In this study, we showed that the cytotoxicity was enhanced by transfection ...

journal_title：Cell biochemistry and biophysics

authors： Liu H,Liu Z,Jiang B,Huo L,Liu J,Lu J

更新日期：2015-06-01 00:00:00

abstract：:Curcumin possesses anti-cancer effects. In the current study, we tested the effect of curcumin on cell proliferation, viability, apoptosis, cell cycle phases, and activation of the PI3K/Akt pathway in the renal cell carcinoma (RCC) cell line RCC-949. We observed that cell proliferation and viability were markedly inhi...

journal_title：Cell biochemistry and biophysics

authors： Zhang H,Xu W,Li B,Zhang K,Wu Y,Xu H,Wang J,Zhang J,Fan R,Wei J

更新日期：2015-12-01 00:00:00

abstract：:Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

journal_title：Cell biochemistry and biophysics

authors： Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

更新日期：2009-01-01 00:00:00

abstract：:The objective of this study is to investigate the roles of acteoside (ACT) in cells with oxygen-glucose deprivation and reoxygenation (OGD/R)-induced injury and the underlying mechanisms. The differentially expressed genes (DEGs) in rats with middle cerebral artery occlusion were identified using GSE61616 data set. Ky...

journal_title：Cell biochemistry and biophysics

authors： Wu W,Wu G,Cao D

更新日期：2021-01-13 00:00:00

abstract：:The ubiquitous Na+/H+ exchanger NHE1 is regulated by protein phosphorylation events, but the mechanisms involved are incompletely understood. We recently cloned NHE1 from the red blood cells of the winter flounder, Pleuronectes americanus (paNHE1), and demonstrated its activation by osmotic cell shrinkage, beta-adrene...

journal_title：Cell biochemistry and biophysics

authors： Holt ME,King SA,Cala PM,Pedersen SF

更新日期：2006-01-01 00:00:00

abstract：:The precise regulation of both the magnitude and the duration of Janus kinase (JAK) catalytic activity is essential for the cytokine orchestration of many biological processes, and the dysregulation of JAK activity has pathological implications. Immunosuppressive disease states, such as X-linked severe combined immuno...

journal_title：Cell biochemistry and biophysics

authors： Duhé RJ,Wang LH,Farrar WL

更新日期：2001-01-01 00:00:00

abstract：:Our objective was to explore the effects of miR-92a and miR-126 on myocardial apoptosis in mouse ischemia-reperfusion model and further investigate the underlying mechanisms. Eighteen Kunming mice were selected and randomly divided into sham operation group and ischemia-reperfusion group with nine mice in each group. ...

journal_title：Cell biochemistry and biophysics

authors： Jiang C,Ji N,Luo G,Ni S,Zong J,Chen Z,Bao D,Gong X,Fu T

更新日期：2014-12-01 00:00:00

abstract：:Anions enter from the cytoplasm into the channel pore of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel not via a central pathway but via a single lateral portal or fenestration. High Cl- conductance is dependent on electrostatic attraction of cytoplasmic Cl- ions by four positively charged...

journal_title：Cell biochemistry and biophysics

authors： Linsdell P,Negoda A,Cowley EA,El Hiani Y

更新日期：2020-03-01 00:00:00