Expression and functional significance of ezrin in human brain astrocytoma.

abstract：:The functions of membrane proteins are highly dependent on their phospholipid environment. In this article, we have used a hydrophobic photolabeling method to study the noncovalent interactions between plasma membrane calcium pump (PMCA) and surrounding phospholipids. With this approach, we determined (1) the number o...

journal_title：Cell biochemistry and biophysics

authors： Villamil Giraldo AM,Castello PR,González Flecha FL,Delfino JM,Rossi JP

更新日期：2006-01-01 00:00:00

abstract：:The umami taste receptor is a heterodimer composed of two members of the T1R taste receptor family: T1R1 and T1R3. The homology models of the ligand binding domains of the human umami receptor have been constructed based on crystallographic structures of the taste receptor of the central nervous system. Furthermore, t...

journal_title：Cell biochemistry and biophysics

authors： Dang Y,Gao X,Xie A,Wu X,Ma F

更新日期：2014-12-01 00:00:00

abstract：:Cyclic ADP-ribose (cADPR) is a cyclic metabolite of NAD+ synthesised in cells and tissues expressing ADP-ribosyl cyclases. Although it was first discovered in sea-urchin egg extracts as a potent calcium mobilizing agent, subsequent studies have indicated that it may have a widespread action in the activation of calciu...

journal_title：Cell biochemistry and biophysics

authors： Galione A,Cui Y,Empson R,Iino S,Wilson H,Terrar D

更新日期：1998-01-01 00:00:00

abstract：:To study the protective effect of mitochondrial ATP-sensitive K(+) channel (mitoK(ATP) channel) opener, nicorandil, combined with Na(+)/Ca(2+) exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in isolated rat hearts; the isolated rat heart was perfused by modified Langendorff device, after 15-min bal...

journal_title：Cell biochemistry and biophysics

authors： Jia D

更新日期：2011-07-01 00:00:00

abstract：:A fast-track clinical pathway is designed to streamline patient care delivery and maximize cost effectiveness. It has decreased postoperative length of stay (LOS) and hospital charges for many surgical procedures. However, data on clinical pathways after liver surgery are sparse. This study examined whether use of a f...

journal_title：Cell biochemistry and biophysics

authors： Lin DX,Li X,Ye QW,Lin F,Li LL,Zhang QY

更新日期：2011-11-01 00:00:00

abstract：:To facilitate drug development for lung delivery, it is highly demanding to establish appropriate airway epithelial cell models as transport barriers to evaluate pharmacokinetic profiles of drug molecules. Besides the cancer-derived cell lines, as the primary cell model, normal human bronchial epithelial (NHBE) cells ...

journal_title：Cell biochemistry and biophysics

authors： Min KA,Rosania GR,Shin MC

更新日期：2016-06-01 00:00:00

abstract：:The number of fatalities and economic losses caused by the Ebola virus infection across the planet culminated in the havoc that occurred between August and November 2014. However, little is known about the molecular protein profile of this devastating virus. This work represents a thorough bioinformatics analysis of t...

journal_title：Cell biochemistry and biophysics

authors： Polanco C,Samaniego Mendoza JL,Buhse T,Uversky VN,Bañuelos Chao IP,Bañuelos Cedano MA,Tavera FM,Tavera DM,Falconi M,Ponce de León AV

更新日期：2018-09-01 00:00:00

abstract：:The state of crosslinking of microfilaments and the state of myosin-driven contraction are the main determinants of the mechanical properties of the cell cortex underneath the membrane, which is significant for the mechanism of shaping cells. Therefore, any change in the contractile state of the actomyosin network wou...

journal_title：Cell biochemistry and biophysics

authors： Karl I,Bereiter-Hahn J

更新日期：1998-01-01 00:00:00

abstract：:Early events in individual hepatocytes of rat activated by adrenaline (10(-6)M) and phenylephrine (10(-5)M) have been investigated by quantitative image microfluorometry and microspectrofluorometry. Cationic DiOC2 and anionic SqSC4 probes have been used for image analysis and transmembrane potential (ΔΨ p) estimation ...

journal_title：Cell biochemistry and biophysics

authors： Kavok NS,Malyukina MY,Borovoy IA,Obukchova EN,Klimov SA

更新日期：2013-11-01 00:00:00

abstract：:Synaptic glutamate receptors play a prominent role in the excitatory neurotransmission in the vertebrate central nervous system. Although elucidation of the functional properties of glutamate receptors using electrophysiologic analyses has yielded important information, methodological and technological limitations hav...

journal_title：Cell biochemistry and biophysics

authors： Vaithianathan T,Manivannan K,Kleene R,Bahr BA,Dey MP,Dityatev A,Suppiramaniam V

更新日期：2005-01-01 00:00:00

abstract：:Resveratrol (RSV) is known for its antioxidant properties; however, this compound has been proposed to have cytotoxic and pro-oxidant effects depending on its concentration and time of exposure. We previously reported the cell cycle arrest effect of low doses of RSV in GRX cells, an activated hepatic stellate cell mod...

journal_title：Cell biochemistry and biophysics

authors： Martins LA,Coelho BP,Behr G,Pettenuzzo LF,Souza IC,Moreira JC,Borojevic R,Gottfried C,Guma FC

更新日期：2014-03-01 00:00:00

abstract：:The objective of this study was to evaluate the protective effect of recombinant human brain natriuretic peptide (rhBNP) on endotoxin-induced acute kidney injury (AKI) in canine model of septic shock and its potential mechanisms. Dogs with endotoxin-induced septic shock were subjected to intravenous infusion of saline...

journal_title：Cell biochemistry and biophysics

authors： Li N,Jin HX,Song Z,Bai CZ,Cui Y,Gao Y

更新日期：2014-11-01 00:00:00

abstract：:Semaphorin4D (Sema4D) belongs to Semaphorins family and is secreted and membrane-bound protein. Its function on angiogenesis and axon regeneration makes it an ideal therapeutic target for spinal cord injury (SCI). Here we examined Sema4D expression profile by real-time PCR and western blot and found Sema4D was upregul...

journal_title：Cell biochemistry and biophysics

authors： Zhang HL,Wang J,Tang L

更新日期：2014-04-01 00:00:00

abstract：:Pro-domain of a cysteine cathepsin contains a highly conserved Ex2Rx2Fx2Nx3Ix3N (ERFNIN) motif. The zymogen structure of cathepsins revealed that the Arg(R) residue of the motif is a central residue of a salt-bridge/H-bond network, stabilizing the scaffold of the pro-domain. Importance of the arginine is also demonstr...

journal_title：Cell biochemistry and biophysics

authors： Aich P,Biswas S

更新日期：2018-06-01 00:00:00

abstract：:A quality control method of highly diluted and potentized homeopathic remedies is important for curing patients applying homeopathic therapy. Lenger detected photons in highly potentized homeopathic remedies by delayed luminescence. The photons of Argentum metallicum 100MK and Cantharis 100MK magnetically bound to the...

journal_title：Cell biochemistry and biophysics

authors： Lenger K,Bajpai RP,Spielmann M

更新日期：2014-03-01 00:00:00

abstract：:To examine the antiproliferative effect of the combination of docetaxel and sorafenib, applied to the representative non-small cell lung cancer cell line A549 cells either wild type or with acquired resistance to docetaxel (A549/D). The aim of this study is to evaluate the synergistic effect of combination treatment o...

journal_title：Cell biochemistry and biophysics

authors： He X,Zhang T

更新日期：2014-03-01 00:00:00

abstract：:Either the role of the adaptive immune system or the interaction between innate and adaptive immune systems in familial Mediterranean fever (FMF) is not clear so far. So, we planned to search for the interaction between the innate and adaptive immune systems in the pathogenesis of FMF by investigating polymorphism for...

journal_title：Cell biochemistry and biophysics

authors： Gunesacar R,Erken E,Dinkci S

更新日期：2013-03-01 00:00:00

abstract：:Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

journal_title：Cell biochemistry and biophysics

authors： Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

更新日期：2014-09-01 00:00:00

abstract：:Diabetic cardiomyopathy is a leading cause of morbidity and mortality, and Insulin2 mutant (Ins2+/-) Akita is a genetic mice model of diabetes relevant to humans. Dicer, miRNAs, and inflammatory cytokines are associated with heart failure. However, the differential expression of miRNAs, dicer, and inflammatory molecul...

journal_title：Cell biochemistry and biophysics

authors： Chavali V,Tyagi SC,Mishra PK

更新日期：2014-01-01 00:00:00

abstract：:The aim is to study the anticancer effect of CXCR4 gene knockdown by CXCR4-siRNA in nude mice model of ovarian cancer. Injecti the SW626 tumor cells which had been transfected by vectors to make nude mouse model of ovarian cancer. The model mice were divided into interference group, negative control group, and blank c...

journal_title：Cell biochemistry and biophysics

authors： Liu W,Wang Y,Wang H,Wang A

更新日期：2014-12-01 00:00:00

abstract：:cDNAs encoding two PDE-3 or cyclic GMP-inhibited (cGI) cyclic nucleotide phosphodiesterase (PDE) isoforms, RPDE-3B (RcGIP1) and HPDE-3A (HcGIP2), were cloned from rat (R) adipose tissue and human (H) heart cDNA libraries. Deletion and N- and C-terminal truncation mutants were expressed in Escherichia coli in order to ...

journal_title：Cell biochemistry and biophysics

authors： He R,Komas N,Ekholm D,Murata T,Taira M,Hockman S,Degerman E,Manganiello VC

更新日期：1998-01-01 00:00:00

abstract：:A new intraoperative cisplatin administration method for patients with locally advanced gastric cancer (AGC) and without peritoneal metastasis, fibrin-sealant-delivered cisplatin chemotherapy, was reported, and its safety, pharmacokinetics, and efficacy were compared with cisplatin hyperthermic intraperitoneal perfusi...

journal_title：Cell biochemistry and biophysics

authors： Huang O,Lu X,Xu X,Shi Y

更新日期：2015-03-01 00:00:00

abstract：:Herpes simplex virus (HSV) is one of the most common viruses infecting humans and animals. Cellular adhesion is increased in HSV and plays a role in pathogenesis of inflammatory response during this viral infection. In our study, we studied a potential role of glycyrrhizin in disrupting cellular adhesion in HSV. We is...

journal_title：Cell biochemistry and biophysics

authors： Huang W,Chen X,Li Q,Li P,Zhao G,Xu M,Xie P

更新日期：2012-01-01 00:00:00

abstract：:In 1903, George Hulett explained how solute alters water in an aqueous solution to lower the vapor pressure of its water. Hulett also explained how the same altered water causes osmosis and osmotic pressure when the solution is separated from liquid water by a membrane permeable to the water only. Hulett recognized th...

journal_title：Cell biochemistry and biophysics

authors： Hammel HT,Schlegel WM

更新日期：2005-01-01 00:00:00

abstract：:Red blood cell (RBC) adhesion to vessel wall endothelium is a potent catalyst of vascular occlusion and occurs in oxidative stress states such as hemoglobinopathies and cardiovascular conditions. These are often treated with vitamin E (VitE), a "classic" antioxidant. In this study, we examined the effects of VitE on R...

journal_title：Cell biochemistry and biophysics

authors： Koshkaryev A,Barshtein G,Yedgar S

更新日期：2010-04-01 00:00:00

abstract：:Our objective is to investigate the promoting effect of hypoxic preconditioning combined with microbubble (MB)-mediated ultrasound (US) on the SDF-1/CXCR4 expression and the migration ability of mesenchymal stem cells (MSCs). Based on the uniform design, the parameters of MB-mediated US, such as the total treatment ti...

journal_title：Cell biochemistry and biophysics

authors： Li L,Wu S,Li P,Zhuo L,Gao Y,Xu Y

更新日期：2015-12-01 00:00:00

abstract：:The three-dimensional structure of the saccharopine reductase enzyme from the budding yeast Saccharomyces cerevisiae was determined to 1.7-A resolution in the apo form by using molecular replacement. The enzyme monomer consists of three domains: domain I is a variant of the Rossmann fold, domain II folds into a alpha/...

journal_title：Cell biochemistry and biophysics

authors： Andi B,Cook PF,West AH

更新日期：2006-01-01 00:00:00

abstract：:Intensive treatment for newborns with trisomy 13 is controversial because of their lethal prognosis. We report the better life prognosis of patients with trisomy 13 who received intensive treatment. At our hospital, we provided an intensive management to such patients including resuscitation and surgical procedures as...

journal_title：Cell biochemistry and biophysics

authors： Tsukada K,Imataka G,Suzumura H,Arisaka O

更新日期：2012-07-01 00:00:00

abstract：:The objective is to explore the clinical curative effects of methylprednisolone combined with MTX and DXM intrathecal injection in treating neuropsychiatric systemic lupus erythematosus (NPSLE) and its effects on autoantibody level and anti-N-methyl-D-aspartate receptor subtype NR2a/2b antibody (anti-NR2 antibody) lev...

journal_title：Cell biochemistry and biophysics

authors： Wang J,Zhao Y,Zhang J,Lei H,Zhu G,Fu B

更新日期：2014-11-01 00:00:00

abstract：:To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

journal_title：Cell biochemistry and biophysics

authors： Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

更新日期：2014-06-01 00:00:00