The protective effect of mitochondrial ATP-sensitive K+ channel opener, nicorandil, combined with Na+/Ca2+ exchange blocker KB-R7943 on myocardial ischemia-reperfusion injury in rat.

abstract：:Human salivary aldehyde dehydrogenase (hsALDH) enzyme appears to be the first line of defense in the body against exogenous toxic aldehydes. However till date much work has not been done on this important member of the ALDH family. In this study, we have purified hsALDH to homogeneity by diethylaminoethyl-cellulose (D...

journal_title：Cell biochemistry and biophysics

authors： Alam MF,Laskar AA,Choudhary HH,Younus H

更新日期：2016-09-01 00:00:00

abstract：:The calcium channel gamma subunits comprise an eight-member protein family that share a common topology consisting of four transmembrane domains and intracellular N- and C-termini. Although the first gamma subunit was identified as an auxiliary subunit of a voltage-dependent calcium channel, a review of phylogenetic, ...

journal_title：Cell biochemistry and biophysics

authors： Chen RS,Deng TC,Garcia T,Sellers ZM,Best PM

更新日期：2007-01-01 00:00:00

abstract：:Insulin increases glucose uptake and metabolism in skeletal muscle by signal transduction via protein phosphorylation cascades. Insulin action on signal transduction is impaired in skeletal muscle from Type 2 diabetic subjects, underscoring the contribution of molecular defects to the insulin resistant phenotype. This...

journal_title：Cell biochemistry and biophysics

authors： Karlsson HK,Zierath JR

更新日期：2007-01-01 00:00:00

abstract：:This study aims to explore the safety and efficacy of intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) in elderly (≥80 years old) acute ischemic stroke (AIS) patients. The clinical data of patients who were treated in Tianjin Huanhu Hospital from June 2012 to November 2013 were retr...

journal_title：Cell biochemistry and biophysics

authors： Chen Y,Li CH,Wang YX,Zhang CH,Dong Z,Zhang FF,Wang JH,Zhang PL

更新日期：2015-07-01 00:00:00

abstract：:Early events in individual hepatocytes of rat activated by adrenaline (10(-6)M) and phenylephrine (10(-5)M) have been investigated by quantitative image microfluorometry and microspectrofluorometry. Cationic DiOC2 and anionic SqSC4 probes have been used for image analysis and transmembrane potential (ΔΨ p) estimation ...

journal_title：Cell biochemistry and biophysics

authors： Kavok NS,Malyukina MY,Borovoy IA,Obukchova EN,Klimov SA

更新日期：2013-11-01 00:00:00

abstract：:To examine the antiproliferative effect of the combination of docetaxel and sorafenib, applied to the representative non-small cell lung cancer cell line A549 cells either wild type or with acquired resistance to docetaxel (A549/D). The aim of this study is to evaluate the synergistic effect of combination treatment o...

journal_title：Cell biochemistry and biophysics

authors： He X,Zhang T

更新日期：2014-03-01 00:00:00

abstract：:In 1903, George Hulett explained how solute alters water in an aqueous solution to lower the vapor pressure of its water. Hulett also explained how the same altered water causes osmosis and osmotic pressure when the solution is separated from liquid water by a membrane permeable to the water only. Hulett recognized th...

journal_title：Cell biochemistry and biophysics

authors： Hammel HT,Schlegel WM

更新日期：2005-01-01 00:00:00

abstract：:In this study, our aim was to assess the coronary flow reserve (CFR) by performing the adenosine stress (99m)Tc-MIBI single-photon computed tomographic (SPECT) myocardial perfusion imaging in patients with hypertension. 47 hypertensive patients with normal coronary angiography were divided into 2 groups, defined by th...

journal_title：Cell biochemistry and biophysics

authors： Fu Q,Zhang Q,Lu W,Wang Y,Huang Y,Wang Y,Wu Q,Lu C

更新日期：2015-11-01 00:00:00

abstract：:In the present study, the changes of the regulatory T cells (Treg) expression, endotoxin translocation, and the relationships in intestinal lymph nodes were investigated in porcine sepsis induced by severe burns. Flow cytometry, western blot, and Tachypleus amebocyte lysate were applied to study after the burn injury ...

journal_title：Cell biochemistry and biophysics

authors： Zu H,Li Q,Huang P

更新日期：2014-12-01 00:00:00

abstract：:Spectral karyotyping is a novel technique for chromosome analysis that has been developed based on the approach of the fluorescence in situ hybridization technique. Spectral karyotyping makes it feasible to diagnose a variety of diseases, because of its technology in painting each of the 24 human chromosomes with diff...

journal_title：Cell biochemistry and biophysics

authors： Imataka G,Arisaka O

更新日期：2012-01-01 00:00:00

abstract：:Ecto-mesenchymal stem cells (EMSCs) originate from the cranial neural crest and participate in the formation of tooth, salivary, and muscle in early development stage. The transplantation of EMSCs, a potential source of myoblast stem cell, might improve muscle regeneration. The purpose of this study was to explore whe...

journal_title：Cell biochemistry and biophysics

authors： Nie X,Xing Y,Deng M,Gang L,Liu R,Zhang Y,Wen X

更新日期：2014-09-01 00:00:00

abstract：:Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds. This study was designed to evaluate the cardioprotec...

journal_title：Cell biochemistry and biophysics

authors： Adluri RS,Thirunavukkarasu M,Zhan L,Maulik N,Svennevig K,Bagchi M,Maulik G

更新日期：2013-11-01 00:00:00

abstract：:Bioactive materials present important micro-environmental cues that induce specific intracellular signaling responses which ultimately determine cell behavior. For example, vascular endothelial cells on a normal vessel wall resist inflammation and thrombosis, but the same cells seeded on an artificial vascular graft o...

journal_title：Cell biochemistry and biophysics

authors： Caplan MR,Shah MM

更新日期：2009-01-01 00:00:00

abstract：:The aim of the study was to investigate the influence of radiotherapy on IL-2 and IL-6 secretions of mucous epithelial cells of small intestine and the inhibition effect of deproteinized calf blood extractive (DCBE, also known as Actovegin in trade name) on apoptosis of mucous epithelial cells of small intestine. 50 w...

journal_title：Cell biochemistry and biophysics

authors： Liu B,Li X,Ai F,Wang T,Chen Y,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:This study describes clinical experience and curative effect of radiophotographically controlled nasointestinal intubation in the treatment of small intestine arrangement in recurrent postoperative adhesive ileus. A 300-cm-long nasointestinal tube was installed into the jejunum through the nasal cavity under radiophot...

journal_title：Cell biochemistry and biophysics

authors： Li RH,Li DC,Lv XP,Quan B

更新日期：2015-06-01 00:00:00

abstract：:Insulin, the major secreted product of the beta-cells of the islets of Langerhans, is initially synthesized as a precursor (preproinsulin), from which the mature hormone is excised by a series of proteolytic cleavages. This review provides a personal narrative of some of the key research projects leading to the identi...

journal_title：Cell biochemistry and biophysics

authors： Davidson HW

更新日期：2004-01-01 00:00:00

abstract：:Herpes simplex virus (HSV) is one of the most common viruses infecting humans and animals. Cellular adhesion is increased in HSV and plays a role in pathogenesis of inflammatory response during this viral infection. In our study, we studied a potential role of glycyrrhizin in disrupting cellular adhesion in HSV. We is...

journal_title：Cell biochemistry and biophysics

authors： Huang W,Chen X,Li Q,Li P,Zhao G,Xu M,Xie P

更新日期：2012-01-01 00:00:00

abstract：:Molecular dynamics simulations, binding free energy calculations, principle component analysis (PCA), and residue interaction network analysis were employed in order to investigate the molecular mechanism of M184I single mutation which played pivotal role in making the HIV-1 reverse transcriptase (RT) totally resistan...

journal_title：Cell biochemistry and biophysics

authors： Moonsamy S,Bhakat S,Walker RC,Soliman ME

更新日期：2016-03-01 00:00:00

abstract：:The precise regulation of both the magnitude and the duration of Janus kinase (JAK) catalytic activity is essential for the cytokine orchestration of many biological processes, and the dysregulation of JAK activity has pathological implications. Immunosuppressive disease states, such as X-linked severe combined immuno...

journal_title：Cell biochemistry and biophysics

authors： Duhé RJ,Wang LH,Farrar WL

更新日期：2001-01-01 00:00:00

abstract：:There are over 10,000 C2H2-type zinc finger (ZF) domains distributed among more than 1,000 ZF proteins in the human genome. These domains are frequently observed to be involved in sequence-specific DNA binding, and uncharacterized domains are typically assumed to facilitate DNA interactions. However, some ZFs also fac...

journal_title：Cell biochemistry and biophysics

authors： Brayer KJ,Kulshreshtha S,Segal DJ

更新日期：2008-01-01 00:00:00

abstract：:H5N1 is a subtype of the influenza A virus that can cause disease in humans and many other animal species. Oseltamivir (Tamiflu) is a potent and selective antiviral drug employed to fight the flu virus in infected individuals by inhibiting neuraminidase (NA), a flu protein responsible for the release and spread of the...

journal_title：Cell biochemistry and biophysics

authors： Karthick V,Ramanathan K

更新日期：2014-03-01 00:00:00

abstract：:Currently, autologous bone marrow-derived stem cell is one of the most innovative areas of stem cells research. Previous studies on animal models of nervous system diseases have shown that these cells have a good effect on nervous system disorders. The alternative treatment with stem cells for the nervous system disea...

journal_title：Cell biochemistry and biophysics

authors： Ren C,Geng RL,Ge W,Liu XY,Chen H,Wan MR,Geng DQ

更新日期：2014-05-01 00:00:00

abstract：:Hip fracture is a kind of osteoporotic fractures in elderly patients. Its important monitoring indicator is to measure bone mineral density (BMD) using DXA. The stress characteristics and material distribution in different parts of the bones can be well simulated by three-dimensional finite element analysis. Our previ...

journal_title：Cell biochemistry and biophysics

authors： Lin ZL,Li PF,Pang ZH,Zheng XH,Huang F,Xu HH,Li QL

更新日期：2015-11-01 00:00:00

abstract：:Reactive oxygen species (ROS) are involved in a variety of biological phenomena, such as mutation, carcinogenesis, inflammation, aging, development, and signal transduction. Intracellular generation of ROS might lead to the activation of redox signaling or oxidative stress. Nonetheless, it is difficult to estimate whe...

journal_title：Cell biochemistry and biophysics

authors： Martinovich GG,Martinovich IV,Cherenkevich SN,Sauer H

更新日期：2010-11-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is a member of the pterin family that has a core structure of pyrazino-2,3-d-pyrimidine rings. Because BH4 is an essential cofactor for the biosynthesis of nitric oxide (a major vasodilator), there is growing interest in BH4 biochemistry in endothelial cells (the cells that line blood vessels...

journal_title：Cell biochemistry and biophysics

authors： Shi W,Meininger CJ,Haynes TE,Hatakeyama K,Wu G

更新日期：2004-01-01 00:00:00

abstract：:Diabetic cardiomyopathy is a leading cause of morbidity and mortality, and Insulin2 mutant (Ins2+/-) Akita is a genetic mice model of diabetes relevant to humans. Dicer, miRNAs, and inflammatory cytokines are associated with heart failure. However, the differential expression of miRNAs, dicer, and inflammatory molecul...

journal_title：Cell biochemistry and biophysics

authors： Chavali V,Tyagi SC,Mishra PK

更新日期：2014-01-01 00:00:00

abstract：:Intensive treatment for newborns with trisomy 13 is controversial because of their lethal prognosis. We report the better life prognosis of patients with trisomy 13 who received intensive treatment. At our hospital, we provided an intensive management to such patients including resuscitation and surgical procedures as...

journal_title：Cell biochemistry and biophysics

authors： Tsukada K,Imataka G,Suzumura H,Arisaka O

更新日期：2012-07-01 00:00:00

abstract：:The aim of the present work is to evaluate the effect of caffeine, the world's most popular psychoactive drug, on the electric activity of the rat's brain that exposed to extremely low-frequency magnetic field (ELF-MF), during 15 days. The obtained results showed that administration of caffeine in a group of rats by d...

journal_title：Cell biochemistry and biophysics

authors： El Gohary MI,Salama AA,El Saeid AA,El Sayed TM,Kotb HSh

更新日期：2013-01-01 00:00:00

abstract：:One nanosecond molecular dynamic (MD) simulation of anti-hen egg white lysozyme (HEL) antibody HyHEL63 (HH63) complexed with HEL reveals rigid and flexible regions of the HH63 binding site. Fifty conformations, extracted from the MD trajectory at regular time intervals were superimposed on HH63-HEL X-ray crystal struc...

journal_title：Cell biochemistry and biophysics

authors： Sinha N,Smith-Gill SJ

更新日期：2005-01-01 00:00:00

abstract：:We wished to study the efficacy and safety of the retrograde ligation of short hepatic veins (SHVs) and the right hepatic vein (HV) through the retrohepatic tunnel in patients who underwent hemihepatectomy due to large hepatic carcinoma in the right lobe of the liver. Right hemihepatectomy was performed in 23 patients...

journal_title：Cell biochemistry and biophysics

authors： Qin Q,Wang L,Li H,Li A,Ouyang J,Xie S,Liang Z

更新日期：2012-01-01 00:00:00