On the analysis of large-scale genomic structures.

abstract：:A number of case-control studies have been conducted to investigate the relationship between the ATP-binding cassette transporter A1 (ABCA1) gene polymorphisms and risk of coronary heart disease (CHD). However, the results have been inconclusive. The purpose of the present study is to investigate whether this polymorp...

journal_title：Cell biochemistry and biophysics

authors： Liu N,Hou M,Ren W,Cao J,Wu H,Zhou W

更新日期：2015-01-01 00:00:00

abstract：:Danggui Sini decoction (DSD), a famous Chinese medicine, has been used therapeutically in various diseases. In this study, we tried to investigate whether and how DSD could ameliorate myelosuppression in an animal model, in which myelosuppression is induced by cyclophosphamide treatment. The myelosuppression model was...

journal_title：Cell biochemistry and biophysics

authors： Chen QQ,Han X,Wang WM,Zhao L,Chen A

更新日期：2015-03-01 00:00:00

abstract：:The aim of this study was to analyze the relationship between oolong tea drinking and bone mineral density in postmenopausal Han Chinese women, while living and diet habits, fertility, disease elements and other baseline conditions were controlled. One group included 124 cases who routinely drank oolong tea, and the o...

journal_title：Cell biochemistry and biophysics

authors： Wang G,Liu G,Zhao H,Zhang F,Li S,Chen Y,Zhang Z

更新日期：2014-11-01 00:00:00

abstract：:We identified significantly higher expression of the genes glycogen debranching enzyme 6 (AGL), enolase 1 (ENOSF1), ectonucleotide pyrophosphatase 2 (ENPP2_1), glutathione S-transferase 3 (GSTM3_3) and mannosidase (MAN2B2) from human left cerebrums versus chimpanzees. Yet the distinct low- and high-expression AGL, ENO...

journal_title：Cell biochemistry and biophysics

authors： Sun L,Wang L,Jiang M,Huang J,Lin H

更新日期：2011-12-01 00:00:00

abstract：:The prevalence of cardiovascular disease (CVD) is increasing dramatically especially in developing countries like India. CVD is a leading cause of morbidity and mortality. There has been a growing awareness of the role of nutrients in the prevention of CVD. One specific recommendation in the battle against CVD is the ...

journal_title：Cell biochemistry and biophysics

authors： Cao Y,Lu L,Liang J,Liu M,Li X,Sun R,Zheng Y,Zhang P

更新日期：2015-05-01 00:00:00

abstract：:Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is a rare form of primary liver cancer (PLC). It is difficult to make a correct preoperative diagnosis of cHCC-CC because of the lack of special features of the disease. We here present a case of a 68-year-old man who presented with fluctuant fever, ch...

journal_title：Cell biochemistry and biophysics

authors： E C,Xie Y,Yang Y,Ji D,Li W,Zhang X

更新日期：2014-05-01 00:00:00

abstract：:Early events in individual hepatocytes of rat activated by adrenaline (10(-6)M) and phenylephrine (10(-5)M) have been investigated by quantitative image microfluorometry and microspectrofluorometry. Cationic DiOC2 and anionic SqSC4 probes have been used for image analysis and transmembrane potential (ΔΨ p) estimation ...

journal_title：Cell biochemistry and biophysics

authors： Kavok NS,Malyukina MY,Borovoy IA,Obukchova EN,Klimov SA

更新日期：2013-11-01 00:00:00

abstract：:The objective of this study was to assess the clinical and histopathological relationship between pulmonary fibrosis and type 1 diabetes. We examined clinical pulmonary function parameters and transbronchial lung biopsies to assess associated histopathological changes in 12 type 1 diabetic patients presenting with dys...

journal_title：Cell biochemistry and biophysics

authors： Hu Y,Ma Z,Guo Z,Zhao F,Wang Y,Cai L,Yang J

更新日期：2014-11-01 00:00:00

abstract：:Recent studies have shown that endothelial progenitor cells (EPCs) participated in angiogenic effects of nicotine and nicotine dose dependently increased the functional activity of early EPCs. The effects of nicotine on late EPCs remain to be determined. Therefore, we investigated whether nicotine had influences on th...

journal_title：Cell biochemistry and biophysics

authors： Yu M,Li Z,Shu Z,Liu Q,Sun J,Tan X

更新日期：2014-11-01 00:00:00

abstract：:Osteoclast is the only cell that can degrade bone tissue in vivo. Recent studies have shown the important role of cytoskeleton dynamics in osteolysis and the formation of podosome belt in osteoclasts. This process is regulated by the dynamic microtubule (MT) network. We treated osteoclast precursor cells Raw264.7 with...

journal_title：Cell biochemistry and biophysics

authors： Ti Y,Zhou L,Wang R,Zhao J

更新日期：2015-03-01 00:00:00

abstract：:We have examined the association of insulin receptors (IR) and downstream signaling molecules with membrane microdomains in rat basophilic leukemia (RBL-2H3) cells following treatment with insulin or tris(2-pyridinecarbxylato)chromium(III) (Cr(pic)(3)). Single-particle tracking demonstrated that individual IR on these...

journal_title：Cell biochemistry and biophysics

authors： Al-Qatati A,Winter PW,Wolf-Ringwall AL,Chatterjee PB,Van Orden AK,Crans DC,Roess DA,Barisas BG

更新日期：2012-04-01 00:00:00

abstract：:Curcumin is a yellow-orange dye widely used as a spice, food coloring and food preservative. It also exhibits a broad range of therapeutic effects against different disorders such as cancer, diabetes, or neurodegenerative diseases. As a compound insoluble in water curcumin accumulates in cell membranes and due to this...

journal_title：Cell biochemistry and biophysics

authors： Duda M,Cygan K,Wisniewska-Becker A

更新日期：2020-06-01 00:00:00

abstract：:Mutations of the retinoblastoma tumor suppressor, pRb, or its cyclin-cyclin-dependent kinase (CDK) regulatory kinases or CDK inhibitors, allows unrestrained E2F activity, leading to unregulated cell cycle progression. However, overexpression of E2F-1 also sensitizes cells to apoptosis, suggesting that targeting this p...

journal_title：Cell biochemistry and biophysics

authors： Nip J,Hiebert SW

更新日期：2000-01-01 00:00:00

abstract：:Nano-drug delivery systems have proven to be an efficient formulation tool to overcome the challenges with current antibiotics therapy and resistance. A series of pH-responsive lipid molecules were designed and synthesized for future liposomal formulation as a nano-drug delivery system for vancomycin at the infection ...

journal_title：Cell biochemistry and biophysics

authors： Ahmed S,Vepuri SB,Jadhav M,Kalhapure RS,Govender T

更新日期：2018-06-01 00:00:00

abstract：:Promotion of apoptosis (which is frequently dependent on functional p53) is thought to be critical for the effectiveness of chemotherapy or radiotherapy. Studies in this as well as other laboratories have demonstrated that breast tumor cells are relatively refractory to apoptosis in response to modalities that induce ...

journal_title：Cell biochemistry and biophysics

authors： Gewirtz DA,Sundaram S,Magnet KJ

更新日期：2000-01-01 00:00:00

abstract：:To facilitate drug development for lung delivery, it is highly demanding to establish appropriate airway epithelial cell models as transport barriers to evaluate pharmacokinetic profiles of drug molecules. Besides the cancer-derived cell lines, as the primary cell model, normal human bronchial epithelial (NHBE) cells ...

journal_title：Cell biochemistry and biophysics

authors： Min KA,Rosania GR,Shin MC

更新日期：2016-06-01 00:00:00

abstract：:To quantify myocardial glucose metabolism by (18)F-FDG PET/CT in patients that have coronary heart disease (CHD) according to traditional Chinese medicine classification. Ninety patients with CHD were enrolled and were categorized into three groups. All patients underwent PET-CT examination for (18)F-FDG uptake quanti...

journal_title：Cell biochemistry and biophysics

authors： Tan YY,Liu DF,Zhu F,Ding XM,Wang GM

更新日期：2015-07-01 00:00:00

abstract：:Proper administration of antithrombotic and antiplatelet drugs after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS) and renal insufficiency is a challenging task. In this study, we utilized Fondaparinux and Tirofiban (either separately or combined) to treat post-PCI patients wi...

journal_title：Cell biochemistry and biophysics

authors： Changjiang H,Jian Q,Yuan Z,Liang Y,Puqing L,Xiaolong G

更新日期：2015-12-01 00:00:00

abstract：:Zirconia-based ceramics is widely used in dentistry. Different compositions of ceramics have different features. Our self-renovated ceramics become more machinable without scarifying its dental restoration properties after adjusting ratio of lanthanum phosphate (LaPO4)/yttrium oxide (Y2O3). In order to evaluate its sa...

journal_title：Cell biochemistry and biophysics

authors： Hua N,Zhu H,Zhuang J,Chen L

更新日期：2014-12-01 00:00:00

abstract：:Semaphorin4D (Sema4D) belongs to Semaphorins family and is secreted and membrane-bound protein. Its function on angiogenesis and axon regeneration makes it an ideal therapeutic target for spinal cord injury (SCI). Here we examined Sema4D expression profile by real-time PCR and western blot and found Sema4D was upregul...

journal_title：Cell biochemistry and biophysics

authors： Zhang HL,Wang J,Tang L

更新日期：2014-04-01 00:00:00

abstract：:Structural organization of the cytoplasm by compartmentation is a well established fact for the eukaryotic cell. In prokaryotes, compartmentation is less obvious. Most prokaryotes do not need intracytoplasmic membranes to maintain their vital functions. This review, especially dealing with prokaryotes, will point out ...

journal_title：Cell biochemistry and biophysics

authors： Hoppert M,Mayer F

更新日期：1999-01-01 00:00:00

abstract：:Peroxisomal and mitochondrial carnitine acetyltransferase (CAT; EC 2.3.1.7) isozymes are synthesized from the first and second ATG codons of the open reading frame of one gene, Candida tropicalis CAT. Primer extension analysis and RNase protection assay revealed that the peroxisomal CAT, initiating at the second AUG c...

journal_title：Cell biochemistry and biophysics

authors： Tanaka A,Ueda M

更新日期：2000-01-01 00:00:00

abstract：:The elimination of viral covalently closed circular DNA (cccDNA) from the nucleus of infected hepatocytes is an obstacle to achieving sustained viral clearance during antiviral therapy of chronic hepatitis B virus (HBV) infection. The aim of our study was to determine whether treatment with siRNA is able to suppress v...

journal_title：Cell biochemistry and biophysics

authors： Li G,Jiang G,Lu J,Chen S,Cui L,Jiao J,Wang Y

更新日期：2014-07-01 00:00:00

abstract：:The umami taste receptor is a heterodimer composed of two members of the T1R taste receptor family: T1R1 and T1R3. The homology models of the ligand binding domains of the human umami receptor have been constructed based on crystallographic structures of the taste receptor of the central nervous system. Furthermore, t...

journal_title：Cell biochemistry and biophysics

authors： Dang Y,Gao X,Xie A,Wu X,Ma F

更新日期：2014-12-01 00:00:00

abstract：:MicroRNAs (miRs) play important roles in initiation and progression of many pathologic processes. However, the roles of miRs in diabetic nephropathy remain unclear. This study was to determine whether miR-21 was involved in diabetic nephropathy and to explore the relationship between miR-21 and MMP9/TIMP1 expression i...

journal_title：Cell biochemistry and biophysics

authors： Wang J,Gao Y,Ma M,Li M,Zou D,Yang J,Zhu Z,Zhao X

更新日期：2013-11-01 00:00:00

abstract：:The possibility that binuclear dinitrosyl iron complexes with glutathione and cysteine (DNIC-GSН and B-DNIC-Cys) have a strong cytotoxic effect on the growth of endometrioid tumours (EMT) in rats with surgically induced experimental endometriosis established in our previous studies has been supported with experimental...

journal_title：Cell biochemistry and biophysics

authors： Burgovа EN,Khristidis YI,Kurkov AV,Mikoyan VD,Shekhter AB,Adamyan LV,Timashev PS,Vanin AF

更新日期：2019-03-01 00:00:00

abstract：:To explore the proteomic changes of placental trophoblastic cells in preeclampsia-eclampsia (PE), placental trophoblastic cells from normally pregnant women and women with hypertension during gestational period were prepared by laser capture microdissection (LCM), and proteins isolated from these cells were subjected ...

journal_title：Cell biochemistry and biophysics

authors： Ma K,Jin H,Hu R,Xiong Y,Zhou S,Ting P,Cheng Y,Yang Y,Yang P,Li X

更新日期：2014-06-01 00:00:00

abstract：:A quality control method of highly diluted and potentized homeopathic remedies is important for curing patients applying homeopathic therapy. Lenger detected photons in highly potentized homeopathic remedies by delayed luminescence. The photons of Argentum metallicum 100MK and Cantharis 100MK magnetically bound to the...

journal_title：Cell biochemistry and biophysics

authors： Lenger K,Bajpai RP,Spielmann M

更新日期：2014-03-01 00:00:00

abstract：:Tetrahydrobiopterin (BH4) is a member of the pterin family that has a core structure of pyrazino-2,3-d-pyrimidine rings. Because BH4 is an essential cofactor for the biosynthesis of nitric oxide (a major vasodilator), there is growing interest in BH4 biochemistry in endothelial cells (the cells that line blood vessels...

journal_title：Cell biochemistry and biophysics

authors： Shi W,Meininger CJ,Haynes TE,Hatakeyama K,Wu G

更新日期：2004-01-01 00:00:00

abstract：:The overview demonstrates how the use of only one physico-chemical approach, viz., the electron paramagnetic resonance method, allowed detection and identification of dinitrosyl iron complexes with thiol-containing ligands in various animal and bacterial cells. These complexes are formed in biological objects in the p...

journal_title：Cell biochemistry and biophysics

authors： Vanin AF

更新日期：2018-06-01 00:00:00