Influence of topoisomerase II inhibitors and ionizing radiation on growth arrest and cell death pathways in the breast tumor cell.

abstract：:The remarkable ability of living cells to sense, process, and respond to mechanical stimuli in their environment depends on the rapid and efficient interconversion of mechanical and chemical energy at specific times and places within the cell. For example, application of force to cells leads to conformational changes ...

journal_title：Cell biochemistry and biophysics

authors： Lele TP,Kumar S

更新日期：2007-01-01 00:00:00

abstract：:To explore therapeutic effects and underlying mechanism of Salubrinal combined with Ulinastatin (UTI) on acute Paraquat (PQ) poisoning. Four hundred rats were randomly allocated into UTI group, SAL group, SAL + UTI and control group according to random number table with 100 rats in each group. Acute PQ poisoning model...

journal_title：Cell biochemistry and biophysics

authors： Guo H,Jiang C,Sun X

更新日期：2014-12-01 00:00:00

abstract：:Circumstantial evidence frequently implicates oxygen-derived free radicals and oxidative stress as mediators of myocardial ischemia/reperfusion (I/R) injury. Therefore, external supplementation of natural antioxidants plays a main role as cardioprotective compounds. This study was designed to evaluate the cardioprotec...

journal_title：Cell biochemistry and biophysics

authors： Adluri RS,Thirunavukkarasu M,Zhan L,Maulik N,Svennevig K,Bagchi M,Maulik G

更新日期：2013-11-01 00:00:00

abstract：:Surfactin, purified from Bacillus subtilis natto TK-1, inhibited proliferation of human breast cancer MCF-7 cells in a dose- and time-dependent manner, with IC(50) at 24, 48, and 72 h of 82.6, 27.3, and 14.8 microM, respectively. Surfactin-induced cell death was considered to be apoptotic by observing the typical apop...

journal_title：Cell biochemistry and biophysics

authors： Cao X,Wang AH,Jiao RZ,Wang CL,Mao DZ,Yan L,Zeng B

更新日期：2009-01-01 00:00:00

abstract：:The umami taste receptor is a heterodimer composed of two members of the T1R taste receptor family: T1R1 and T1R3. The homology models of the ligand binding domains of the human umami receptor have been constructed based on crystallographic structures of the taste receptor of the central nervous system. Furthermore, t...

journal_title：Cell biochemistry and biophysics

authors： Dang Y,Gao X,Xie A,Wu X,Ma F

更新日期：2014-12-01 00:00:00

abstract：:Tissue restoration is the process whereby multiple damaged cell types are replaced to restore the histoarchitecture and function to the tissue. Several theories have been proposed to explain the phenomenon of tissue restoration in amphibians and in animals belonging to higher orders. These theories include dedifferent...

journal_title：Cell biochemistry and biophysics

authors： Young HE,Duplaa C,Romero-Ramos M,Chesselet MF,Vourc'h P,Yost MJ,Ericson K,Terracio L,Asahara T,Masuda H,Tamura-Ninomiya S,Detmer K,Bray RA,Steele TA,Hixson D,el-Kalay M,Tobin BW,Russ RD,Horst MN,Floyd JA,Henson NL

更新日期：2004-01-01 00:00:00

abstract：:Hepatocyte growth factor (HGF) has been known to enhance the growth of normal hepatocytes, but also to inhibit the growth of neoplastic cells. This article examines the involvement of HGF in the hepatocarcinogenesis caused by peroxisome proliferators (PPs). Up to 78 wk after male F-344 rats were orally given (4-chloro...

journal_title：Cell biochemistry and biophysics

authors： Suga T,Motoki Y,Tamura H,Watanabe T

更新日期：2000-01-01 00:00:00

abstract：:Escherichia coli has four hydrogenases (Hyd), three genes of which are encoded by the hya, hyb, and hyc operons. The proton-reducing and hydrogen-oxidizing activities of Hyd-2 (hyb) were analyzed in whole cells grown to stationary phase and cell extracts, respectively, during glycerol fermentation using novel double m...

journal_title：Cell biochemistry and biophysics

authors： Trchounian K,Soboh B,Sawers RG,Trchounian A

更新日期：2013-05-01 00:00:00

abstract：:A quality control method of highly diluted and potentized homeopathic remedies is important for curing patients applying homeopathic therapy. Lenger detected photons in highly potentized homeopathic remedies by delayed luminescence. The photons of Argentum metallicum 100MK and Cantharis 100MK magnetically bound to the...

journal_title：Cell biochemistry and biophysics

authors： Lenger K,Bajpai RP,Spielmann M

更新日期：2014-03-01 00:00:00

abstract：:By using a functional approach of reconstituting detergent-solubilized membrane proteins into liposomes and following their function in patch-clamp experiments, we identified a novel mechanosensitive (MS) channel in the thermophilic cell wall-less archaeon Thermoplasma volcanium. Sodium dodecyl sulfate polyacrylamide ...

journal_title：Cell biochemistry and biophysics

authors： Kloda A,Martinac B

更新日期：2001-01-01 00:00:00

abstract：:The CEP genes play a pivotal role in the replication of the cell. CEP family proteins form the major constituents of the centrosome and play a prominent role in centriole biogenesis and in cell replication. Alteration in CEP genes will result in disruption of cell cycle that may in turn cause cancer. In our study, we ...

journal_title：Cell biochemistry and biophysics

authors： Gopalakrishnan C,Kamaraj B,Purohit R

更新日期：2014-12-01 00:00:00

abstract：:Danggui Sini decoction (DSD), a famous Chinese medicine, has been used therapeutically in various diseases. In this study, we tried to investigate whether and how DSD could ameliorate myelosuppression in an animal model, in which myelosuppression is induced by cyclophosphamide treatment. The myelosuppression model was...

journal_title：Cell biochemistry and biophysics

authors： Chen QQ,Han X,Wang WM,Zhao L,Chen A

更新日期：2015-03-01 00:00:00

abstract：:3-Iodothyronamine (T1AM) is regarded as a hormone-like substance thanks to its endogenous nature, its interaction with specific receptors trace amine-associated receptor 1 and its biological effects. We characterized T1AM transport and conversion in an in vitro culture of H9c2 murine cells, after a T1AM bolus injectio...

journal_title：Cell biochemistry and biophysics

authors： Orsi G,Ghelardoni S,Saba A,Zucchi R,Vozzi G

更新日期：2014-01-01 00:00:00

abstract：:The ubiquitous Na+/H+ exchanger NHE1 is regulated by protein phosphorylation events, but the mechanisms involved are incompletely understood. We recently cloned NHE1 from the red blood cells of the winter flounder, Pleuronectes americanus (paNHE1), and demonstrated its activation by osmotic cell shrinkage, beta-adrene...

journal_title：Cell biochemistry and biophysics

authors： Holt ME,King SA,Cala PM,Pedersen SF

更新日期：2006-01-01 00:00:00

abstract：:This study is aimed to investigate the efficacy and underlying the mechanism of propofol in treatment of ischemia reperfusion (IR)-induced lung injury in rats, providing a novel insight of therapeutic strategy for IR-induced lung injury. 120 healthy SD rats were selected and randomly divided into sham operation group,...

journal_title：Cell biochemistry and biophysics

authors： Yang P,Yang N,Zhang X,Xu X

更新日期：2014-12-01 00:00:00

abstract：:The aim of this study was to investigate characteristic CT manifestations of the group of ovarian thecoma-fibroma. 24 patients (26 lesions) presenting with the ovarian thecoma-fibroma were analyzed retrospectively, and the diagnosis were confirmed by pathology after surgery. Our findings included: 22 patients were uni...

journal_title：Cell biochemistry and biophysics

authors： Zhang Z,Wu Y,Gao J

更新日期：2015-03-01 00:00:00

abstract：:Cotton bollworm, Helicoverpa armigera, is one of the most damaging polyphagous pests worldwide, which has developed high levels of resistance to commonly applied insecticides. Mitochondrial P-glycoprotein (Pgp) was detected in the insecticide-resistant strain of H. armigera using C219 antibodies, and its possible role...

journal_title：Cell biochemistry and biophysics

authors： Akbar SM,Aurade RM,Sharma HC,Sreeramulu K

更新日期：2014-09-01 00:00:00

abstract：:It has been long known that the oncogenic extracellular environment plays an indispensable role in developing and nurturing cancer cell progression and in resistance to standard treatments. However, by how much the biophysical components of tumour extracellular environment contribute to these processes is uncertain. I...

journal_title：Cell biochemistry and biophysics

authors： Sarwar M,Sykes PH,Chitcholtan K,Evans JJ

更新日期：2021-01-12 00:00:00

abstract：:The purpose of this study was to investigate the incidence and risk factors of infections associated with totally implantable venous-access ports (TIVAPs) in our hospital. From April 2007 through November 2013, a total of 1,026 patients with TIVAP were included in this study. We retrospectively analyzed the incidence ...

journal_title：Cell biochemistry and biophysics

authors： Ji L,Yang J,Miao J,Shao Q,Cao Y,Li H

更新日期：2015-05-01 00:00:00

abstract：:A rapid capillary electrophoresis method using carboxymethyl-β-cyclodextrin (CM-β-CD) as chiral selector was developed and validated for the enantiomeric purity determination of levamlodipine besylate bulk drug. Several parameters for were optimized for a satisfactory enantioresolution, including pH of background elec...

journal_title：Cell biochemistry and biophysics

authors： Qi Y,Zhang X

更新日期：2014-12-01 00:00:00

abstract：:Red blood cell (RBC) adhesion to vessel wall endothelium is a potent catalyst of vascular occlusion and occurs in oxidative stress states such as hemoglobinopathies and cardiovascular conditions. These are often treated with vitamin E (VitE), a "classic" antioxidant. In this study, we examined the effects of VitE on R...

journal_title：Cell biochemistry and biophysics

authors： Koshkaryev A,Barshtein G,Yedgar S

更新日期：2010-04-01 00:00:00

abstract：:The aim is to study the anticancer effect of CXCR4 gene knockdown by CXCR4-siRNA in nude mice model of ovarian cancer. Injecti the SW626 tumor cells which had been transfected by vectors to make nude mouse model of ovarian cancer. The model mice were divided into interference group, negative control group, and blank c...

journal_title：Cell biochemistry and biophysics

authors： Liu W,Wang Y,Wang H,Wang A

更新日期：2014-12-01 00:00:00

abstract：:The ubiquitin-proteasome system (UPS) is the primary pathway responsible for the recognition and degradation of misfolded, damaged, or tightly regulated proteins in addition to performing essential roles in DNA repair, cell cycle regulation, cell migration, and the immune response. While traditional biochemical techni...

journal_title：Cell biochemistry and biophysics

authors： Melvin AT,Woss GS,Park JH,Waters ML,Allbritton NL

更新日期：2013-09-01 00:00:00

abstract：:The calcium channel gamma subunits comprise an eight-member protein family that share a common topology consisting of four transmembrane domains and intracellular N- and C-termini. Although the first gamma subunit was identified as an auxiliary subunit of a voltage-dependent calcium channel, a review of phylogenetic, ...

journal_title：Cell biochemistry and biophysics

authors： Chen RS,Deng TC,Garcia T,Sellers ZM,Best PM

更新日期：2007-01-01 00:00:00

abstract：:Mutations of the retinoblastoma tumor suppressor, pRb, or its cyclin-cyclin-dependent kinase (CDK) regulatory kinases or CDK inhibitors, allows unrestrained E2F activity, leading to unregulated cell cycle progression. However, overexpression of E2F-1 also sensitizes cells to apoptosis, suggesting that targeting this p...

journal_title：Cell biochemistry and biophysics

authors： Nip J,Hiebert SW

更新日期：2000-01-01 00:00:00

abstract：:To evaluate the correlation between CT perfusion parameters and tumor angiogenesis, expression of VEGF is implanted in VX2 lung tumor. VX2 tumor cells were injected in 15 healthy New Zealand rabbits. After 20 days, tumors with diameter over 7 mm were scanned with 16 row spiral CT. Using Software Perfusion 3, blood flo...

journal_title：Cell biochemistry and biophysics

authors： Ling S,Deng D,Mo Y,Zhang X,Guan X,Wei Q

更新日期：2014-09-01 00:00:00

abstract：:The aim of the study was to investigate the influence of radiotherapy on IL-2 and IL-6 secretions of mucous epithelial cells of small intestine and the inhibition effect of deproteinized calf blood extractive (DCBE, also known as Actovegin in trade name) on apoptosis of mucous epithelial cells of small intestine. 50 w...

journal_title：Cell biochemistry and biophysics

authors： Liu B,Li X,Ai F,Wang T,Chen Y,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:Behcet's disease (BD) accompanied by intestinal involvement is called intestinal BD. Although recent studies have attained positive feedback with the administration of anti-TNF-α agents in patients with BD, only a few reports on the study of etanercept in intestinal BD have been found. In this study, 35 cases of intes...

journal_title：Cell biochemistry and biophysics

authors： Ma D,Zhang CJ,Wang RP,Wang L,Yang H

更新日期：2014-07-01 00:00:00

abstract：:The n-alkane-assimilating diploid yeast, Candida tropicalis, possesses two acetoacetyl-CoA thiolase (Thiolase I) isozymes encoded by one allele: peroxisomal and cytosolic Thiolase Is encoded by both CT-T1A and CT-T1B. To clarify the function of peroxisomal and cytosolic Thiolase Is, the site-directed mutation leading ...

journal_title：Cell biochemistry and biophysics

authors： Ueda M,Kanayama N,Tanaka A

更新日期：2000-01-01 00:00:00

abstract：:To assess the image quality of monochromatic imaging from spectral CT in patients with Budd-Chiari syndrome (BCS), fifty patients with BCS underwent spectral CT to generate conventional 140 kVp polychromatic images (group A) and monochromatic images, with energy levels from 40 to 80, 40 + 70, and 50 + 70 keV fusion im...

journal_title：Cell biochemistry and biophysics

authors： Su L,Dong J,Sun Q,Liu J,Lv P,Hu L,Yan L,Gao J

更新日期：2014-11-01 00:00:00